Earth's magnetic field enabled scalar coupling relaxation of 13C nuclei bound to fast-relaxing quadrupolar 14N in amide groups

Journal of Magnetic Resonance

Volumn 227, Issue , 2013, Pages 35-38

  Chiavazza, Enrico ^a,b   Kubala, Eugen ^a,c   Gringeri, Concetta V ^a,d   Düwel, Stephan ^a,d   Durst, Markus ^a,d   Schulte, Rolf F ^a   Menzel, Marion I ^a  

^a GE GLOBAL RESEARCH   (Germany)

^b UNIVERSITY OF TURIN   (Italy)

^c JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

13C MR Spectroscopy; Dissolution DNP; Hyperpolarization; Nuclear spin relaxation; Scalar coupling; Spin lattice relaxation time

Indexed keywords

DISSOLUTION DNP; HYPERPOLARIZATION; MR SPECTROSCOPY; NUCLEAR SPIN RELAXATION; SCALAR COUPLING;

AMINO ACIDS; MAGNETIC FIELDS; MAGNETIC RESONANCE SPECTROSCOPY; SCANNING; SPIN-LATTICE RELAXATION;

AMIDES;

AMIDE; CARBON; NITROGEN;

ARTICLE; ASTRONOMY; CHEMISTRY; MAGNETIC FIELD; MAGNETOMETRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIATION EXPOSURE;

AMIDES; CARBON ISOTOPES; EARTH (PLANET); MAGNETIC FIELDS; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETOMETRY; NITROGEN;

EID: 84872771848     PISSN: 10907807     EISSN: 10960856     Source Type: Journal    
DOI: 10.1016/j.jmr.2012.11.016     Document Type: Article

References (18)

1. K. Golman, R. in't Zandt, and M. Thaning Real-time metabolic imaging Proc. Natl. Acad. Sci. USA 103 2006 11270 11275
2. 13C-labelled bicarbonate Nature 453 2008 940 943
3. F. Kurdzesau, B. van den Brandt, A. Comment, P. Hautle, S. Jannin, J.J. van der Klink, and J.A. Konter Dynamic nuclear polarization of small labelled molecules in frozen water-alcohol solutions J. Phys. D: Appl. Phys. 41 2008 155506 155516
4. 129Xe Chem. Phys. Lett. 182 1991 538 540
5. C.R. Bowers, and D.P. Weitekamp Parahydrogen and synthesis allow dramatically enhanced nuclear alignment J. Am. Chem. Soc. 109 1987 5541 5542
6. A. Abragam, and M. Goldman Principles of dynamic nuclear polarization Rep. Prog. Phys. 41 1978 395 467
7. J.H. Ardenkjaer-Larsen, S. Machon, and H. Johannesson Dynamic nuclear polarization with trityls at 1.2 K Appl. Magn. Reson. 34 2008 509 522
8. J.H. Ardenkjaer-Larsen, B. Fridlund, A. Gram, G. Hansson, L. Hansson, M.H. Lerche, R. Servin, M. Thaning, and K. Golman Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR Proc. Natl. Acad. Sci. U. S. A. 100 2003 10158 10163
9. 13C magnetic resonance spectroscopy Magn. Res. Med. 66 2011 505 519
10. K. Golman, J.H. Ardenkjær-Larsen, J.S. Petersson, S. Mansson, and I. Leunbach Molecular imaging with endogenous substances Proc. Natl. Acad. Sci. U. S. A. 10 2003 10435 10439
11. 13C magnetic resonance imaging Am. J. Physiol. Renal. Physiol. 302 2012 1658 1662
12. D.M. Wilson, K.R. Keshari, P.E.Z. Larson, A.P. Chen, S. Hua, M. van Criekinge, R. Bok, S.J. Nelson, V. Macdonald, D.B. Vigneron, and J. Kurhanewicz Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo J. Magn. Res. 205 2010 141 147
13. 13C]pyruvate Proc. Int. Soc. Magn. Reson. Med. 19 2011 652
14. 13C and methods for sensitivity enhancement Pure Appl. Chem. 32 1972 51 66
15. L. Lumata, A.K. Jindal, M.E. Merritt, C.R. Malloy, A.D. Sherry, and Z. Kovacs DNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal J. Am. Chem. Soc. 133 2011 8673 8680
16. P. Mielville, S. Jannin, and G. Bodenhausen Relaxometry of insensitive nuclei: optimizing dissolution dynamic nuclear polarization J. Magn. Res. 210 2011 137 140
17. 14N relaxations in aggregated and nonaggregated choline phospholipids J. Am. Chem. Soc. 103 1981 1238
18. H. Allouche-Arnon, A.K. Grant, E. Vinogradov, X. Wang, R.E. Lenkinski, A. Gamliel, R. Nalbandian, L. Frydman, J.M. Gomori, C.M. Barzilay, and R. Katz-Brull In vivo studies on a hyperpolarized choline contrast agent: design and implementation of a new biomarker Proc. Int. Soc. Magn. Reson. Med. 18 2010 4524