The combination of stem cell factor and granulocyte-colony stimulating factor for chronic stroke treatment in aged animals

Experimental and Translational Stroke Medicine

Volumn 4, Issue 1, 2012, Pages

  Piao, Chun Shu ^a   Gonzalez Toledo, Maria E ^a   Gu, Xi ^a   Zhao, Li Ru ^a,b  

^a Louisiana State University Health Sciences Center at Shreveport   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Chronic stroke; Elderly; G CSF; Hematopoietic growth factor; SCF; Treatment

Indexed keywords

RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT STEM CELL FACTOR;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CHEMISTRY; BRAIN CORTEX; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CHRONIC STROKE; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FLOW CYTOMETRY; FUNCTIONAL STATUS; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL MOBILIZATION; TREATMENT OUTCOME;

EID: 84872744906     PISSN: None     EISSN: 20407378     Source Type: Journal    
DOI: 10.1186/2040-7378-4-25     Document Type: Article

References (38)

1. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, et al. Heart Disease and Stroke Statistics-2012 Update: A Report From the American Heart Association. Circulation 2012, 125:e2-e200.
2. Hill MD, Hachinski V. Stroke treatment: time is brain. Lancet 1998, 352:SIII10-4.
3. Pfefferkorn T, Rosenberg GA. Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion. Stroke 2003, 34:2025-2030. 10.1161/01.STR.0000083051.93319.28, 12855824.
4. Warlow C, Sudlow C, Dennis M, Wardlaw J, Sandercock P. Stroke. Lancet 2003, 362:1211-1224. 10.1016/S0140-6736(03)14544-8, 14568745.
5. Welte K, Platzer E, Lu L, Gabrilove JL, Levi E, Mertelsmann R, Moore MA. Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor. Proc Natl Acad Sci USA 1985, 82:1526-1530. 10.1073/pnas.82.5.1526, 397296, 3871951.
6. Zsebo KM, Wypych J, McNiece IK, Lu HS, Smith KA, Karkare SB, et al. Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium. Cell 1990, 63:195-201. 10.1016/0092-8674(90)90300-4, 2208278.
7. Duarte RF, Frank DA. The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF): molecular basis and clinical relevance. Leuk Lymphoma 2002, 43:1179-1187. 10.1080/10428190290026231, 12152985.
8. Hirata T, Morii E, Morimoto M, Kasugai T, Tsujimura T, Hirota S, Kanakura Y, Nomura S, Kitamura Y. Stem cell factor induces outgrowth of c-kit-positive neurites and supports the survival of c-kit- positive neurons in dorsal root ganglia of mouse embryos. Development 1993, 119:49-56.
9. Hirata T, Kasugai T, Morii E, Hirota S, Nomura S, Fujisawa H, Kitamura Y. Characterization of c-kit- positive neurons in the dorsal root ganglion of mouse. Brain Res Dev Brain Res 1995, 85:201-211.
10. Katafuchi T, Li AJ, Hirota S, Kitamura Y, Hori T. Impairment of spatial learning and hippocampal synaptic potentiation in c-kit mutant rats. Learn Mem 2000, 7:383-392. 10.1101/lm.33900, 311355, 11112797.
11. Motro B, Wojtowicz JM, Bernstein A, van der Kooy D. Steel mutant mice are deficient in hippocampal learning but not long-term potentiation. Proc Natl Acad Sci USA 1996, 93:1808-1813. 10.1073/pnas.93.5.1808, 39863, 8700840.
12. Diederich K, Sevimli S, Dörr H, Kösters E, Hoppen M, Lewejohann L, et al. The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice. J Neurosci 2009, 2009(29):11572-11581.
13. Zhao LR, Berra HH, Duan WM, Singhal S, Mehta J, Apkarian AV, Kessler JA. Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats. Stroke 2007, 38:2804-2811. 10.1161/STROKEAHA.107.486217, 17761920.
14. Udenfriend S, Bumpus FM, Foster HL, et al. Spontaneously hypertensive rats: guidelines for breeding, care, and use. Hypertensive mechanisms 1982, 781-801. Stuttgart: Schattauer Verlag, Rascher W, Clough D, Ganten D.
15. National Research Council Mammalian Models for Research on Aging 1981, 48. Washington DC: National academy press, National Research Council.
16. Knox CA, Yates RD, Chen I. Brain aging in normotensive and hypertensive strains of rats. II. Ultrastructural changes in neurons and glia. Acta Neuropathol 1980, 52:7-15.
17. Vogel RW, Ewers M, Ross C, Gould TJ, Woodruff-Pak DS. Age-related impairment in the 250- millisecond delay eyeblink classical conditioning procedure in C57BL/6 mice. Learn Mem 2002, 9:321-336. 10.1101/lm.50902, 187122, 12359840.
18. Williams WM, Stadtman ER, Moskovitz J. Ageing and exposure to oxidative stress in vivo differentially affect cellular levels of PrP in mouse cerebral microvessels and brain parenchyma. Neuropathol Appl Neurobiol 2004, 30:161-168. 10.1111/j.1365-2990.2003.00523.x, 15043713.
19. Piao CS, Gonzalez-Toledo ME, Xue YQ, Duan WM, Terao S, Granger DN, Kelley RE, Zhao LR. The role of stem cell factor and granulocyte-colony stimulating factor in brain repair during chronic stroke. J Cereb Blood Flow Metab 2009, 29:759-770. 10.1038/jcbfm.2008.168, 19209180.
20. Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 2002, 174:11-20. 10.1006/exnr.2001.7853, 11869029.
21. Zhao LR, Navalitloha Y, Singhal S, Mehta J, Piao CS, Guo WP, Kessler JA, Groothuis DR. Hematopoietic growth factors pass through the blood-brain barrier in intact rats. Exp Neurol 2007, 204:569-573. 10.1016/j.expneurol.2006.12.001, 3099460, 17307165.
22. Zhao LR, Singhal S, Duan WM, Mehta J, Kessler JA. Brain repair by hematopoietic growth factors in a rat model of stroke. Stroke 2007, 38:2584-2591. 10.1161/STROKEAHA.106.476457, 17656664.
23. Ohlsson AL, Johansson BB. Environment influences functional outcome of cerebral infarction in rats. Stroke 1995, 26:644-649. 10.1161/01.STR.26.4.644, 7709412.
24. De Ryck M, Van Reempts J, Borgers M, Wauquier A, Janssen PA. Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats. Stroke 1989, 20:1383-1390. 10.1161/01.STR.20.10.1383, 2799870.
25. Gurwitz JH, Avorn J. The ambiguous relation between aging and adverse drug reactions. Ann Intern Med 1991, 114:956-966.
26. Turnheim K. Drug dosage in the elderly. Is it rational?. Drugs Aging 1998, 13:357-379. 10.2165/00002512-199813050-00003, 9829164.
27. Johansson BB, Auer LM, Sayama I. Reaction of pial arteries and veins to hypercapnia in hypertensive and normotensive rats. Stroke 1985, 16:320-323. 10.1161/01.STR.16.2.320, 3975971.
28. Johansson BB. Cerebral vascular bed in hypertension and consequences for the brain. Hypertension 1984, 6:III81-III86. 10.1161/01.HYP.6.6_Pt_2.III81, 6519759.
29. Barone FC, Price WJ, White RF, Willette RN, Feuerstein GZ. Genetic hypertension and increased susceptibility to cerebral ischemia. Neurosci Biobehav Rev 1992, 16:219-233. 10.1016/S0149-7634(05)80182-4, 1630732.
30. Coyle P. Different susceptibilities to cerebral infarction in spontaneously hypertensive (SHR) and normotensive Spraque-Dawley rats. Stroke 1986, 17:520-525. 10.1161/01.STR.17.3.520, 3715954.
31. Duverger D, MacKenzie ET. The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age. J Cereb Blood Flow Metab 1988, 8:449-461. 10.1038/jcbfm.1988.86, 2968987.
32. Grabowski M, Nordborg C, Brundin P, Johansson BB. Middle cerebral artery occlusion in the hypertensive and normotensive rat: a study of histopathology and behaviour. J Hypertens 1988, 6:405-411.
33. Stroemer RP, Kent TA, Hulsebosch CE. Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke 1995, 26:2135-2144. 10.1161/01.STR.26.11.2135, 7482662.
34. Zhao LR, Mattsson B, Johansson BB. Environmental influence on brain-derived neurotrophic factor messenger RNA expression after middle cerebral artery occlusion in spontaneously hypertensive rats. Neuroscience 2000, 97:177-184. 10.1016/S0306-4522(00)00023-3, 10771349.
35. Zhao LR, Risedal A, Wojcik A, Hejzlar J, Johansson BB, Kokaia Z. Enriched environment influences brain-derived neurotrophic factor levels in rat forebrain after focal stroke. Neurosci Lett 2001, 305:169-172. 10.1016/S0304-3940(01)01837-7, 11403932.
36. Facon T, Harousseau JL, Maloisel F, Attal M, Odriozola J, Alegre A, Schroyens W, Hulin C, Schots R, Marin P, Guilhot F, Granena A, De Waele M, Pigneux A, Méresse V, Clark P, Reiffers J. Stem cell factor in combination with filgrastim after chemotherapy improves peripheral blood progenitor cell yield and reduces apheresis requirements in multiple myeloma patients: a randomized, controlled trial. Blood 1999, 94:1218-1225.
37. Stiff P, Gingrich R, Luger S, Wyres MR, Brown RA, LeMaistre CF, Perry J, Schenkein DP, List A, Mason JR, Bensinger W, Wheeler C, Freter C, Parker WRL, Emmanouilides C. A randomized phase 2 study of PBPC mobilization by stem cell factor and filgrastim in heavily pretreated patients with Hodgkin's disease or non-Hodgkin's lymphoma. Bone Marrow Transplant 2000, 26:471-481. 10.1038/sj.bmt.1702531, 11019835.
38. To LB, Bashford J, Durrant S, MacMillan J, Schwarer AP, Prince HM, Gibson J, Lewis I, Swart B, Marty J, Rawling T, Ashman L, Charles S, Cohen B. Successful mobilization of peripheral blood stem cells after addition of ancestim (stem cell factor) in patients who had failed a prior mobilization with filgrastim (granulocyte colony-stimulating factor) alone or with chemotherapy plus filgrastim. Bone Marrow Transplant 2003, 31:371-378. 10.1038/sj.bmt.1703860, 12634728.