The gracilis myocutaneous free flap in swine: An advantageous preclinical model for vascularized composite allograft transplantation research

Microsurgery

Volumn 33, Issue 1, 2013, Pages 51-55

  Leto Barone, Angelo A ^a   Leonard, David A ^a   Torabi, Radbeh ^a   Mallard, Christopher ^a   Glor, Taylor ^a   Scalea, Joseph R ^a   Randolph, Mark A ^a   Sachs, David H ^a   Cetrulo, Curtis L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOTRANSPLANTATION; ANIMAL TISSUE; ARTICLE; CAROTID ARTERY; END TO END ANASTOMOSIS; FASCIA; GRACILIS FLAP; GRACILIS MUSCLE; INTERNAL JUGULAR VEIN; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS TISSUE; SWINE; VASCULARIZED COMPOSITE ALLOTRANSPLANTATION; VEIN BLOOD FLOW;

ANASTOMOSIS, SURGICAL; ANIMALS; CAROTID ARTERY, COMMON; FEMORAL ARTERY; FEMORAL VEIN; FREE TISSUE FLAPS; GRAFT SURVIVAL; JUGULAR VEINS; MODELS, ANIMAL; MUSCLE, SKELETAL; SKIN TRANSPLANTATION; SWINE; TRANSPLANTATION, HOMOLOGOUS;

EID: 84872684110     PISSN: 07381085     EISSN: 10982752     Source Type: Journal    
DOI: 10.1002/micr.21997     Document Type: Article

References (25)

1. Swearingen B, Ravindra K, Xu H, Wu S, Breidenbach WC, Ildstad ST,. Science of composite tissue allotransplantation. Transplantation 2008; 86: 627-635.
2. Wu S, Xu H, Ravindra K, Ildstad ST,. Composite tissue allotransplantation: Past, present and future-The history and expanding applications of CTA as a new frontier in transplantation. Transplant Proc 2009; 41: 463-465.
3. Ravindra KV, Wu S, Bozulic L, Xu H, Breidenbach WC, Ildstad ST,. Composite tissue transplantation: A rapidly advancing field. Transplant Proc 2008; 40: 1237-1248.
4. Dubernard JM, Lengele B, Morelon E, Testelin S, Badet L, Moure C, Beziat JL, Dakpe S, Kanitakis J, D'Hauthuille C, El Jaafari A, Petruzzo P, Lefrancois N, Taha F, Sirigu A, Di Marco G, Carmi E, Bachmann D, Cremades S, Giraux P, Burloux G, Hequet O, Parquet N, Frances C, Michallet M, Martin X, Devauchelle B,. Outcomes 18 months after the first human partial face transplantation. N Engl J Med 2007; 357: 2451-2460.
5. Strome M,. Human laryngeal transplantation: Considerations and implications. Microsurgery 2000; 20: 372-374.
6. Siemionow M, Klimczak A,. Advances in the development of experimental composite tissue transplantation models. Transpl Int 2010; 23: 2-13.
7. Adamson LA, Huang WC, Breidenbach WC, Rahhal D, Xu H, Huang Y, Pidwell DJ, Wei FC, Tobin G, Ildstad ST,. A modified model of hindlimb osteomyocutaneous flap for the study of tolerance to composite tissue allografts. Microsurgery 2007; 27: 630-636.
8. Lee WP, Rubin JP, Cober S, Ierino F, Randolph MA, Sachs DH,. Use of swine model in transplantation of vascularized skeletal tissue allografts. Transplant Proc 1998; 30: 2743-2745.
9. Ren X, Shirbacheh MV, Ustuner ET, Zdichavsky M, Edelstein J, Maldonado C, Breidenbach WC, Frank J, Tobin GR, Jones JW, Barker JH,. Osteomyocutaneous flap as a preclinical composite tissue allograft: Swine model. Microsurgery 2000; 20: 143-149.
10. Kuo YR, Sacks JM, Lee WP, Wu WS, Kueh NS, Yao SF, Chiang YC,. Porcine heterotopic composite tissue allograft transplantation using a large animal model for preclinical studies. Chang Gung Med J 2006; 29: 268-274.
11. Hewitt CW, Ramsamooj R, Patel MP, Yazdi B, Achauer BM, Black KS,. Development of stable mixed T cell chimerism and transplantation tolerance without immune modulation in recipients of vascularized bone marrow allografts. Transplantation 1990; 50: 766-772.
12. Hettiaratchy S, Melendy E, Randolph MA, Coburn RC, Neville DM Jr, Sachs DH, Huang CA, Lee WP,. Tolerance to composite tissue allografts across a major histocompatibility barrier in miniature swine. Transplantation 2004; 77: 514-521.
13. Haughey BH, Panje WR,. A porcine model for multiple musculocutaneous flaps. Laryngoscope 1989; 99: 204-212.
14. Haughey BH, Panje WR,. The porcine gracilis musculocutaneous flap model. Plast Reconstr Surg 1989; 83: 395-396.
15. Sachs DH, Leight G, Cone J, Schwartz S, Stuart L, Rosenberg S,. Transplantation in miniature swine. I. Fixation of the major histocompatibility complex. Transplantation 1976; 22: 559-567.
16. Buncke HJ,. Free flap surgery-Scope and techniques. Scand J Plast Reconstr Surg Suppl 1982; 19: 81-93.
17. Kulahci Y, Klimczak A, Madajka M, Altuntas S, Siemionow M,. Long-term survival of composite hemiface/mandible/tongue allografts correlates with multilineage chimerism development in the lymphoid and myeloid compartments of recipients. Transplantation 2010; 90: 843-852.
18. Siemionow M, Izycki D, Ozer K, Ozmen S, Klimczak A,. Role of thymus in operational tolerance induction in limb allograft transplant model. Transplantation 2006; 81: 1568-1576.
19. Ozer K, Oke R, Gurunluoglu R, Zielinski M, Izycki D, Prajapati R, Siemionow M,. Induction of tolerance to hind limb allografts in rats receiving cyclosporine A and antilymphocyte serum: Effect of duration of the treatment. Transplantation 2003; 75: 31-36.
20. Mundinger GS, Kelamis JA, Kim SH, Magarakis M, Jones LS, Ha JS, Rodriguez ED,. Tunneled superficial inferior epigastric artery (SIEA) myocutaneous/vascularized femur chimeric flaps: A model to study the role of vascularized bone marrow in composite allografts. Microsurgery. 2012; 32: 128-135.
21. Siemionow M, Ozturk C,. An update on facial transplantation cases performed between 2005 and 2010. Plast Reconstr Surg 2011; 128: 707e-720e.
22. Siemionow MZ, Zor F, Gordon CR,. Face, upper extremity, and concomitant transplantation: Potential concerns and challenges ahead. Plast Reconstr Surg 2010; 126: 308-315.
23. Gordon CR, Zor F, Siemionow M,. Skin area quantification in preparation for concomitant upper extremity and face transplantation: A cadaver study and literature review. Transplantation 2011; 91: 1050-1056.
24. Horner BM, Randolph MA, Duran-Struuck R, Hirsh EL, Ferguson KK, Teague AG, Butler PE, Huang CA,. Induction of tolerance to an allogeneic skin flap transplant in a preclinical large animal model. Transplant Proc 2009; 41: 539-541.
25. Lineaweaver WC, Buncke HJ,. Complications of free flap transfers. Hand Clin 1986; 2: 347-351.