Aprepitant: A novel neurokinin-1 receptor/substance P antagonist as antipruritic therapy in cutaneous T-Cell lymphoma

Journal of the American Academy of Dermatology

Volumn 67, Issue 5, 2012, Pages e198-e199

  Ladizinski, Barry ^a   Bazakas, Andrea ^a   Olsen, Elise A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA2B INTERFERON; ANTIPRURITIC AGENT; APREPITANT; MORPHOLINE DERIVATIVE; NEUROKININ 1 RECEPTOR; ONDANSETRON; RECOMBINANT PROTEIN; SUBSTANCE P;

AGED; CASE REPORT; CUTANEOUS T CELL LYMPHOMA; DRUG ANTAGONISM; DRUG COMBINATION; FEMALE; HUMAN; LETTER; PAIN ASSESSMENT;

AGED; ANTIPRURITICS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INTERFERON-ALPHA; LYMPHOMA, T-CELL, CUTANEOUS; MORPHOLINES; ONDANSETRON; PAIN MEASUREMENT; RECEPTORS, NEUROKININ-1; RECOMBINANT PROTEINS; SUBSTANCE P;

EID: 84872682007     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2012.02.008     Document Type: Article

References (5)

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2. Horwitz SM, Olsen EA, Duvic M, Porcu P, Kim YH. Review of the treatment of mycosis fungoides and Sézary syndrome: A stagebased approach. J Natl Compr Canc Netw 2008;6:436-42
3. Hargreaves R, Ferreira JC, Hughes D, Brands J, Hale J, Mattson B, et al. Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapyinduced nausea and vomiting. Ann N Y Acad Sci 2011;1222: 40-8
4. Vincenzi B, Tonini G, Santini D. Aprepitant for erlotinib-induced pruritus. N Engl J Med 2010;363:397-8
5. Booken N, Heck M, Nicolay JP, Klemke CD, Goerdt S, Utikal J. Oral aprepitant in the therapy of refractory pruritus in erythrodermic cutaneous T-cell lymphoma. Br J Dermatol 2011;164:665-7.