Analysis, occurrence and fate of commonly used pharmaceuticals and hormones in the Buyukcekmece Watershed, Turkey

Chemosphere

Volumn 90, Issue 6, 2013, Pages 2004-2012

  Aydin, Egemen ^a   Talinli, Ilhan ^a  

^a ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Environmental analysis; Hormones; Pharmaceuticals; Surface water; Tandem mass spectrometry; Ultra performance liquid chromatography

Indexed keywords

DRUG PRODUCTS; ENDOCRINOLOGY; HORMONES; LAKES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; POTABLE WATER; SURFACE WATERS;

DRINKING WATER SOURCES; ENVIRONMENTAL ANALYSIS; LIMIT OF QUANTIFICATIONS; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; SOLID-PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TRIPLE QUADRUPOLE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTIBIOTICS;

AMOXICILLIN; ANTIBIOTIC AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CAFFEINE; CENTRAL STIMULANT AGENT; CIPROFLOXACIN; DICLOFENAC; DRINKING WATER; ERYTHROMYCIN; ESTRADIOL; ESTRIOL; ESTRONE; ETHINYLESTRADIOL; HORMONE; IBUPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROPRANOLOL; SULFAMETHOXAZOLE; SURFACE WATER;

ANTIBIOTICS; DRUG; HORMONE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; POLLUTION MONITORING; SURFACE WATER; WATERSHED;

ADSORPTION; ARTICLE; LAKE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PHYSICAL CHEMISTRY; QUADRUPOLE MASS SPECTROMETRY; RIVER; SEASONAL VARIATION; SOLID PHASE EXTRACTION; TURKEY (REPUBLIC); ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WASTE WATER; WATER POLLUTION; WATER SAMPLING; WATERSHED;

BUYUKCEKMECE LAKE; ISTANBUL [TURKEY]; TURKEY;

EID: 84872678828     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.10.074     Document Type: Article

References (51)

1. Bendz D., Paxeus N.A., Ginn T.R., Loge F.J. Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Hoje River in Sweden. J. Hazard. Mater. 2005, 122:195-204.
2. Birkett J.W., Lester J.N. Endocrine Disrupters in Wastewater and Sludge Treatment Processes 2003, Lewis Pub, Boca Raton.
3. Birkett D.J., Miners J.O. Caffeine renal clearance and urine caffeine concentrations during steady-state dosing - implications for monitoring caffeine intake during sports-events. Br. J. Clin. Pharmacol. 1991, 31:405-408.
4. Bougie D., Aster R. Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen. Blood 2001, 97:3846-3850.
5. Castiglioni S., Bagnati R., Calamari D., Fanelli R., Zuccato E. A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters. J. Chromatogr. A 2005, 1092:206-215.
6. Conley J.M., Symes S.J., Kindelberger S.A., Richards S.A. Rapid liquid chromatography-tandem mass spectrometry method for the determination of a broad mixture of pharmaceuticals in surface water. J. Chromatogr. A 2008, 1185:206-215.
7. Daneshvar A., Svanfelt J., Kronberg L., Prevost M., Weyhenmeyer G.A. Seasonal variations in the occurrence and fate of basic and neutral pharmaceuticals in a Swedish river-lake system. Chemosphere 2010, 80:301-309.
8. Deshpande A.D., Baheti K.G., Chatterjee N.R. Degradation of β-lactam antibiotics. Curr. Sci. 2004, 87:1684-1695.
9. European Environment Agency, 2010. Pharmaceuticals in the Environment - Result of an EEA Workshop - EEA. Luxembourg.
10. Feitosa-Felizzola J., Chiron S. Occurrence and distribution of selected antibiotics in a small Mediterranean stream (Arc River, Southern France). J. Hydrol. 2009, 364:50-57.
11. Fernandez C., Gonzalez-Doncel M., Pro J., Carbonell G., Tarazona J.V. Occurrence of pharmaceutically active compounds in surface waters of the Henares-Jarama-Tajo river system (Madrid, Spain) and a potential risk characterization. Sci. Total Environ. 2010, 408:543-551.
12. Golet E.M., Alder A.C., Hartmann A., Ternes T.A., Giger W. Trace determination of fluoroquinolone antibacterial agents in solid-phase extraction urban wastewater by and liquid chromatography with fluorescence detection. Anal. Chem. 2001, 73:3632-3638.
13. Gracia-Lor E., Sancho J.V., Hernandez F. Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2011, 1218:2264-2275.
14. Gracia-Lor E., Sancho J.V., Serrano R., Hernandez F. Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia. Chemosphere 2012, 87:453-462.
15. Gros M., Petrovic M., Barcelo D. Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters. Talanta 2006, 70:678-690.
16. Gros M., Petrovic M., Barcelo D. Tracing pharmaceutical residues of different therapeutic classes in environmental waters by using liquid chromatography/quadrupole-linear ion trap mass spectrometry and automated library searching. Anal. Chem. 2009, 81:898-912.
17. Guo Y.C., Krasner S.W. Occurrence of primidone, carbamazepine, caffeine, and precursors for n-nitrosodimethylamine in drinking water sources impacted by wastewater. J. Am. Water Resour. Assoc. 2009, 45:58-67.
18. Halling-Sorensen B., Nielsen S.N., Lanzky P.F., Ingerslev F., Lutzhoft H.C.H., Jorgensen S.E. Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere 1998, 36:357-394.
19. Hernando M.D., Heath E., Petrovic M., Barcelo D. Trace-level determination of pharmaceutical residues by LC-MS/MS in natural and treated waters. A pilot-survey study. Anal. Bioanal. Chem. 2006, 385:985-991.
20. Hilton M.J., Thomas K.V. Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 2003, 1015:129-141.
21. Huggett D.B., Brooks B.W., Peterson B., Foran C.M., Schlenk D. Toxicity of select beta adrenergic receptor-blocking pharmaceuticals (B-blockers) on aquatic organisms. Arch. Environ. Contam. Toxicol. 2002, 43:229-235.
22. Jelic A., Gros M., Ginebreda A., Cespedes-Sanchez R., Ventura F., Petrovic M., Barcelo D. Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment. Water Res. 2011, 45:1165-1176.
23. Jjemba P.K. Excretion and ecotoxicity of pharmaceutical and personal care products in the environment. Ecotoxicol. Environ. Saf. 2006, 63:113-130.
24. Johnson A.C., Williams R.J. A model to estimate influent and effluent concentrations of estradiol, estrone, and ethinylestradiol at sewage treatment works. Environ. Sci. Technol. 2004, 38:3649-3658.
25. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. The effect of signal suppression and mobile phase composition on the simultaneous analysis of multiple classes of acidic/neutral pharmaceuticals and personal care products in surface water by solid-phase extraction and ultra performance liquid chromatography-negative electrospray tandem mass spectrometry. Talanta 2008, 74:1299-1312.
26. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra performance liquid chromatography-electrospray tandem mass spectrometry. Anal. Bioanal. Chem. 2008, 391:1293-1308.
27. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water Res. 2008, 42:3498-3518.
28. Kim S.D., Cho J., Kim I.S., Vanderford B.J., Snyder S.A. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res. 2007, 41:1013-1021.
29. Kleywegt S., Pileggi V., Yang P., Hao C., Zhao X., Rocks C., Thach S., Cheung P., Whitehead B. Pharmaceuticals, hormones and bisphenol A in untreated source and finished drinking water in Ontario, Canada - and treatment efficiency. Sci. Total Environ. 2011, 409:1481-1488.
30. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 2002, 36:1202-1211.
31. Kummerer K. Antibiotics in the aquatic environment - a review - Part II. Chemosphere 2009, 75:435-441.
32. Kuster M., Jose Lopez de Alda M., Dolores Hernando M., Petrovic M., Martin-Alonso J., Barcelo D. Analysis and occurrence of pharmaceuticals, estrogens, progestogens and polar pesticides in sewage treatment plant effluents, river water and drinking water in the Llobregat river basin (Barcelona, Spain). J. Hydrol. 2008, 358:112-123.
33. Mavronikola C., Demetriou M., Hapeshi E., Partassides D., Michael C., Mantzavinos D., Kassinos D. Mineralisation of the antibiotic amoxicillin in pure and surface waters by artificial UVA- and sunlight-induced fenton oxidation. J. Chem. Technol. Biotechnol. 2009, 84:1211-1217.
34. Pailler J.Y., Krein A., Pfister L., Hoffmann L., Guignard C. Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg. Sci. Total Environ. 2009, 407:4736-4743.
35. Routledge E.J., Sumpter J.P. Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen. Environ. Toxicol. Chem. 1996, 15:241-248.
36. Schlusener M.P., Bester K. Determination of steroid hormones, hormone conjugates and macrolide antibiotics in influents and effluents of sewage treatment plants utilising high-performance liquid chromatography/tandem mass spectrometry with electrospray and atmospheric pressure chemical ionisation. Rapid Commun. Mass Spectrom. 2005, 19:3269-3278.
37. Seifrtova M., Pena A., Lino C.M., Solich P. Determination of fluoroquinolone antibiotics in hospital and municipal wastewaters in Coimbra by liquid chromatography with a monolithic column and fluorescence detection. Anal. Bioanal. Chem. 2008, 391:799-805.
38. Sim W.J., Lee J.W., Oh J.E. Occurrence and fate of pharmaceuticals in wastewater treatment plants and rivers in Korea. Environ. Pollut. 2010, 158:1938-1947.
39. Sumpter J.P. Feminized responses in fish to environmental estrogens. Toxicol. Lett. 1995, 82-3:737-742.
40. Sumpter J.P., Jobling S. Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect. 1995, 103:173-178.
41. Ternes T.A. Human Pharmaceuticals, Hormones and Fragrances : The Challenge of Micropollutants in Urban Water Management 2006, IWA Pub., Seattle, WA.
42. Ternes T.A., Hirsch R. Occurrence and behavior of X-ray contrast media in sewage facilities and the aquatic environment. Environ. Sci. Technol. 2000, 34:2741-2748.
43. Vanderford B.J., Pearson R.A., Rexing D.J., Snyder S.A. Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry. Anal. Chem. 2003, 75:6265-6274.
44. Verlicchi P., Galletti A., Petrovic M., Barcelo D. Hospital effluents as a source of emerging pollutants: an overview of micropollutants and sustainable treatment options. J. Hydrol. 2010, 389:416-428.
45. Vieno N.M., Tuhkanen T., Kronberg L. Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection. J. Chromatogr. A 2006, 1134:101-111.
46. Vulliet E., Cren-Olive C. Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption. Environ. Pollut. 2011, 159:2929-2934.
47. Watkinson A.J., Murby E.J., Kolpin D.W., Costanzo S.D. The occurrence of antibiotics in an urban watershed: From wastewater to drinking water. Sci. Total Environ. 2009, 407:2711-2723.
48. Weigel S., Kallenborn R., Huhnerfuss H. Simultaneous solid-phase extraction of acidic, neutral and basic pharmaceuticals from aqueous samples at ambient (neutral) pH and their determination by gas chromatography-mass spectrometry. J. Chromatogr. A 2004, 1023:183-195.
49. Yamamoto A., Kakutani N., Yamamoto K., Kamiura T., Miyakoda H. Steroid hormone profiles of urban and tidal rivers using LC/MS/MS equipped with electrospray ionization and atmospheric pressure photoionization sources. Environ. Sci. Technol. 2006, 40:4132-4137.
50. Ying G.G., Kookana R.S., Ru Y.J. Occurrence and fate of hormone steroids in the environment. Environ. Int. 2002, 28:545-551.
51. Zuccato E., Castiglioni S., Fanelli R. Identification of the pharmaceuticals for human use contaminating the Italian aquatic environment. J. Hazard. Mater. 2005, 122:205-209.