Small hepatocellular carcinomas: Ultrasonography guided percutaneous radiofrequency ablation

Abdominal Imaging

Volumn 38, Issue 1, 2013, Pages 98-111

  Kim, Young Jun ^a   Lee, Min Woo ^b   Park, Hee Sun ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Artificial ascites; Contrast enhanced ultrasonography; Fusion imaging; Hepatocellular carcinoma; Radiofrequency ablation; Ultrasonography

Indexed keywords

ECHO CONTRAST MEDIUM; PERFLUBUTANE; PERFLUTREN; SONOVUE;

ASCITES; CANCER GROWTH; CANCER PATIENT; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; ECHOGRAPHY; FEASIBILITY STUDY; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; REVIEW; THREE DIMENSIONAL IMAGING;

CARCINOMA, HEPATOCELLULAR; CATHETER ABLATION; CONTRAST MEDIA; DISEASE PROGRESSION; HUMANS; LIVER NEOPLASMS; POSTOPERATIVE COMPLICATIONS; RISK FACTORS; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 84872677077     PISSN: 09428925     EISSN: 14320509     Source Type: Journal    
DOI: 10.1007/s00261-012-9883-5     Document Type: Review

References (87)

1. Ferlay J, Shin HR, Bray F, et al. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127:2893-2917
2. Bruix J, Sherman M (2011) Management of hepatocellular carcinoma: an update. Hepatology 53:1020-1022
3. Cho YK, Kim JK, Kim WT, Chung JW (2010) Hepatic resection versus radiofrequency ablation for very early stage hepatocellular carcinoma: a Markov model analysis. Hepatology 51:1284-1290
4. Livraghi T, Meloni F, Di Stasi M, et al. (2007) Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis: is resection still the treatment of choice? Hepatology 47:82-89 (Pubitemid 351171044)
5. Goldberg SN, Grassi CJ, Cardella JF, et al. (2005) Image-guided tumor ablation: standardization of terminology and reporting criteria. Radiology 235:728-739 (Pubitemid 40695866)
6. Mulier S, Ni Y, Jamart J, et al. (2005) Local recurrence after hepatic radiofrequency coagulation: multivariate meta-analysis and review of contributing factors. Ann Surg 242:158-171 (Pubitemid 41033431)
7. Lee MW, Kim YJ, Park HS, et al. (2010) Targeted sonography for small hepatocellular carcinoma discovered by CT or MRI: factors affecting sonographic detection. AJR Am J Roentgenol 194:W396-W400
8. Kim JE, Kim YS, Rhim H, et al. (2011) Outcomes of patients with hepatocellular carcinoma referred for percutaneous radiofrequency ablation at a tertiary center: analysis focused on the feasibility with the use of ultrasonography guidance. Eur J Radiol 79:e80-e84
9. Rhim H, Lee MH, Kim YS, et al. (2008) Planning sonography to assess the feasibility of percutaneous radiofrequency ablation of hepatocellular carcinomas. AJR Am J Roentgenol 190:1324-1330 (Pubitemid 351684908)
10. Brillet PY, Paradis V, Brancatelli G, et al. (2006) Percutaneous radiofrequency ablation for hepatocellular carcinoma before liver transplantation: a prospective study with histopathologic comparison. AJR Am J Roentgenol 186:S296-S305 (Pubitemid 46114734)
11. Fontana RJ, Hamidullah H, Nghiem H, et al. (2002) Percutaneous radiofrequency thermal ablation of hepatocellular carcinoma: a safe and effective bridge to liver transplantation. Liver Transpl 8:1165-1174 (Pubitemid 35469879)
12. Lu DS, Yu NC, Raman SS, et al. (2005) Percutaneous radiofrequency ablation of hepatocellular carcinoma as a bridge to liver transplantation. Hepatology 41:1130-1137 (Pubitemid 40593921)
13. Mazzaferro V, Battiston C, Perrone S, et al. (2004) Radiofrequency ablation of small hepatocellular carcinoma in cirrhotic patients awaiting liver transplantation: a prospective study. Ann Surg 240:900-909 (Pubitemid 39425785)
14. Pompili M, Mirante VG, Rondinara G, et al. (2005) Percutaneous ablation procedures in cirrhotic patients with hepatocellular carcinoma submitted to liver transplantation: assessment of efficacy at explant analysis and of safety for tumor recurrence. Liver Transpl 11:1117-1126 (Pubitemid 41341763)
15. Pulvirenti A, Garbagnati F, Regalia E, et al. (2001) Experience with radiofrequency ablation of small hepatocellular carcinomas before liver transplantation. Transpl Proc 33:1516-1517 (Pubitemid 32237955)
16. Rodriguez-Sanjuan JC, Gonzalez F, Juanco C, et al. (2008) Radiological and pathological assessment of hepatocellular carcinoma response to radiofrequency. A study on removed liver after transplantation. World J Surg 32:1489-1494
17. Lin SM, Lin CJ, Lin CC, et al. (2005) Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less. Gut 54:1151-1156 (Pubitemid 41025911)
18. Shibata T, Isoda H, Hirokawa Y, et al. (2009) Small hepatocellular carcinoma: is radiofrequency ablation combined with transcatheter arterial chemoembolization more effective than radiofrequency ablation alone for treatment? Radiology 252:905-913
19. Shiina S, Teratani T, Obi S, et al. (2005) A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma. Gastroenterology 129:122-130 (Pubitemid 41002049)
20. Cho YK, Kim Y, Rhim H (2009) Pitfalls in the radiological and pathological correlation of tumour response rates of hepatocellular carcinoma following radiofrequency ablation. J Clin Pathol 62:1071-1073
21. Goldberg SN, Gazelle GS, Compton CC, et al. (2000) Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation. Cancer 88:2452-2463 (Pubitemid 30331950)
22. Morimoto M, Sugimori K, Shirato K, et al. (2002) Treatment of hepatocellular carcinoma with radiofrequency ablation: radiologic-histologic correlation during follow-up periods. Hepatology 35:1467-1475 (Pubitemid 34966901)
23. Coad JE, Kosari K, Humar A, Sielaff TD (2003) Radiofrequency ablation causes 'thermal fixation' of hepatocellular carcinoma: a post-liver transplant histopathologic study. Clin Transplant 17:377-384 (Pubitemid 36958201)
24. Martin AP, Goldstein RM, Dempster J, et al. (2006) Radiofrequency thermal ablation of hepatocellular carcinoma before liver transplantation - a clinical and histological examination. Clin Transplant 20:695-705 (Pubitemid 44712269)
25. Netto GJ, Altrabulsi B, Katabi N, et al. (2006) Radio-frequency ablation of hepatocellular carcinoma before liver transplantation: a histologic and 'TUNEL' study. Liver Int 26:746-751 (Pubitemid 43983893)
26. Giorgio A, Di Sarno A, De Stefano G, et al. (2011) Percutaneous radiofrequency ablation of hepatocellular carcinoma compared to percutaneous ethanol injection in treatment of cirrhotic patients: an Italian randomized controlled trial. Anticancer Res 31:2291-2295
27. Xia F, Lai EC, Lau WY, et al. (2012) High serum hyaluronic acid and HBV viral load are main prognostic factors of local recurrence after complete radiofrequency ablation of hepatitis B-related small hepatocellular carcinoma. Ann Surg Oncol 19(4):1284-1291
28. Kim YS, Rhim H, Cho OK, et al. (2006) Intrahepatic recurrence after percutaneous radiofrequency ablation of hepatocellular carcinoma: analysis of the pattern and risk factors. Eur J Radiol 59:432-441 (Pubitemid 44301741)
29. Kudo M (2010) Radiofrequency ablation for hepatocellular carcinoma: updated review in 2010. Oncology 78:113-124
30. Nakazawa T, Kokubu S, Shibuya A, et al. (2007) Radiofrequency ablation of hepatocellular carcinoma: correlation between local tumor progression after ablation and ablative margin. AJR Am J Roentgenol 188:480-488 (Pubitemid 46170753)
31. Okusaka T, Okada S, Ueno H, et al. (2002) Satellite lesions in patients with small hepatocellular carcinoma with reference to clinicopathologic features. Cancer 95:1931-1937 (Pubitemid 35222173)
32. Choi D, Lim HK, Rhim H, et al. (2007) Percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma as a first-line treatment: long-term results and prognostic factors in a large single-institution series. Eur Radiol 17:684-692
33. Hasegawa K, Makuuchi M, Takayama T, et al. (2008) Surgical resection vs. percutaneous ablation for hepatocellular carcinoma: a preliminary report of the Japanese nationwide survey. J Hepatol 49:589-594
34. Hiraoka A, Horiike N, Yamashita Y, et al. (2008) Efficacy of radiofrequency ablation therapy compared to surgical resection in 164 patients in Japan with single hepatocellular carcinoma smaller than 3 cm, along with report of complications. Hepatogastroenterology 55:2171-2174
35. Yun WK, Choi MS, Choi D, et al. (2010) Superior long-term outcomes after surgery in Child-Pugh class a patients with single small hepatocellular carcinoma compared to radiofrequency ablation. Hep Intl 5:722-729
36. Abu-Hilal M, Primrose JN, Casaril A, et al. (2008) Surgical resection versus radiofrequency ablation in the treatment of small unifocal hepatocellular carcinoma. J Gastrointest Surg 12:1521-1526
37. Chen MS, Li JQ, Zheng Y, et al. (2006) A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg 243:321-328 (Pubitemid 43327762)
38. Hong SN, Lee SY, Choi MS, et al. (2005) Comparing the outcomes of radiofrequency ablation and surgery in patients with a single small hepatocellular carcinoma and well-preserved hepatic function. J Clin Gastroenterol 39:247-252 (Pubitemid 40283963)
39. Huang J, Yan L, Cheng Z, et al. (2010) A randomized trial comparing radiofrequency ablation and surgical resection for HCC conforming to the Milan criteria. Ann Surg 252:903-912
40. Lupo L, Panzera P, Giannelli G, et al. (2007) Single hepatocellular carcinoma ranging from 3 to 5 cm: radiofrequency ablation or resection? HPB (Oxf) 9:429-434 (Pubitemid 350215037)
41. Montorsi M, Santambrogio R, Bianchi P, et al. (2005) Survival and recurrences after hepatic resection or radiofrequency for hepatocellular carcinoma in cirrhotic patients: a multivariate analysis. J Gastrointest Surg 9:62-67 (discussion 67-68) (Pubitemid 40037873)
42. Bennett GL, Krinsky GA, Abitbol RJ, et al. (2002) Sonographic detection of hepatocellular carcinoma and dysplastic nodules in cirrhosis: correlation of pretransplantation sonography and liver explant pathology in 200 patients. AJR Am J Roentgenol 179:75-80 (Pubitemid 34694814)
43. Kim CK, Lim JH, Lee WJ (2001) Detection of hepatocellular carcinomas and dysplastic nodules in cirrhotic liver: accuracy of ultrasonography in transplant patients. J Ultrasound Med 20:99-104
44. Liu WC, Lim JH, Park CK, et al. (2003) Poor sensitivity of sonography in detection of hepatocellular carcinoma in advanced liver cirrhosis: accuracy of pretransplantation sonography in 118 patients. Eur Radiol 13:1693-1698 (Pubitemid 36869365)
45. Rode A, Bancel B, Douek P, et al. (2001) Small nodule detection in cirrhotic livers: evaluation with US, spiral CT, and MRI and correlation with pathologic examination of explanted liver. J Comput Assist Tomogr 25:327-336 (Pubitemid 32440782)
46. Yu NC, Chaudhari V, Raman SS, et al. (2011) CT and MRI improve detection of hepatocellular carcinoma, compared with ultrasound alone, in patients with cirrhosis. Clin Gastroenterol Hepatol 9:161-167
47. Koda M, Ueki M, Maeda N, Murawaki Y (2003) Diaphragmatic perforation and hernia after hepatic radiofrequency ablation. AJR Am J Roentgenol 180:1561-1562 (Pubitemid 36687085)
48. Rhim H (2005) Complications of radiofrequency ablation in hepatocellular carcinoma. Abdom Imaging 30:409-418 (Pubitemid 41176118)
49. Rhim H, Lim HK (2009) Radiofrequency ablation for hepatocellular carcinoma abutting the diaphragm: the value of artificial ascites. Abdom Imaging 34:371-380
50. Wood TF, Rose DM, Chung M, et al. (2000) Radiofrequency ablation of 231 unresectable hepatic tumors: indications, limitations, and complications. Ann Surg Oncol 7:593-600
51. Moumouh A, Hannequin J, Chagneau C, et al. (2005) A tamponade leading to death after radiofrequency ablation of hepatocellular carcinoma. Eur Radiol 15:234-237
52. Hinshaw JL, Laeseke PF, Winter TC III, et al. (2006) Radiofrequency ablation of peripheral liver tumors: intraperitoneal 5% dextrose in water decreases postprocedural pain. AJR Am J Roentgenol 186:S306-S310 (Pubitemid 46114735)
53. Park SY, Tak WY, Jeon SW, et al. (2010) The efficacy of intraperitoneal saline infusion for percutaneous radiofrequency ablation for hepatocellular carcinoma. Eur J Radiol 74:536-540
54. Song I, Rhim H, Lim HK, et al. (2009) Percutaneous radiofrequency ablation of hepatocellular carcinoma abutting the diaphragm and gastrointestinal tracts with the use of artificial ascites: safety and technical efficacy in 143 patients. Eur Radiol 19:2630-2640
55. Kondo Y, Yoshida H, Shiina S, et al. (2006) Artificial ascites technique for percutaneous radiofrequency ablation of liver cancer adjacent to the gastrointestinal tract. Br J Surg 93:1277-1282 (Pubitemid 44547029)
56. Rhim H, Lim HK, Kim YS, Choi D (2008) Percutaneous radiofrequency ablation with artificial ascites for hepatocellular carcinoma in the hepatic dome: initial experience. AJR Am J Roentgenol 190:91-98
57. Kang TW, Rhim H, Lee MW, et al. (2011) Radiofrequency ablation for hepatocellular carcinoma abutting the diaphragm: comparison of effects of thermal protection and therapeutic efficacy. AJR Am J Roentgenol 196:907-913
58. Uehara T, Hirooka M, Ishida K, et al. (2007) Percutaneous ultrasound-guided radiofrequency ablation of hepatocellular carcinoma with artificially induced pleural effusion and ascites. J Gastroenterol 42:306-311 (Pubitemid 46681706)
59. Laeseke PF, Sampson LA, Brace CL, et al. (2006) Unintended thermal injuries from radiofrequency ablation: protection with 5% dextrose in water. AJR Am J Roentgenol 186:S249-S254 (Pubitemid 46114727)
60. Nam SY, Rhim H, Kang TW, et al. (2010) Percutaneous radiofrequency ablation for hepatic tumors abutting the diaphragm: clinical assessment of the heat-sink effect of artificial ascites. AJR Am J Roentgenol 194:W227-W231
61. Kim YS, Rhim H, Choi D, Lim HK (2009) Does artificial ascites induce the heat-sink phenomenon during percutaneous radiofrequency ablation of the hepatic subcapsular area? An in vivo experimental study using a rabbit model. Korean J Radiol 10:43-50
62. Shibata T, Iimuro Y, Ikai I, et al. (2002) Percutaneous radiofrequency ablation therapy after intrathoracic saline solution infusion for liver tumor in the hepatic dome. J Vasc Interv Radiol 13:313-315 (Pubitemid 34226420)
63. Minami Y, Kudo M, Kawasaki T, et al. (2003) Percutaneous ultrasound-guided radiofrequency ablation with artificial pleural effusion for hepatocellular carcinoma in the hepatic dome. J Gastroenterol 38:1066-1070 (Pubitemid 38016367)
64. Koda M, Ueki M, Maeda Y, et al. (2004) Percutaneous sonographically guided radiofrequency ablation with artificial pleural effusion for hepatocellular carcinoma located under the diaphragm. AJR Am J Roentgenol 183:583-588 (Pubitemid 39145300)
65. Andreana L, Kudo M, Hatanaka K, et al. (2010) Contrast-enhanced ultrasound techniques for guiding and assessing response to locoregional treatments for hepatocellular carcinoma. Oncology 78(Suppl 1):68-77
66. Meloni MF, Livraghi T, Filice C, et al. (2006) Radiofrequency ablation of liver tumors: the role of microbubble ultrasound contrast agents. Ultrasound Q 22:41-47 (Pubitemid 44510226)
67. Kim TK, Lee KH, Khalili K, Jang HJ (2011) Hepatocellular nodules in liver cirrhosis: contrast-enhanced ultrasound. Abdom Imaging 36:244-263
68. Minami Y, Kudo M, Kawasaki T, et al. (2004) Treatment of hepatocellular carcinoma with percutaneous radiofrequency ablation: usefulness of contrast harmonic sonography for lesions poorly defined with B-mode sonography. AJR Am J Roentgenol 183:153-156 (Pubitemid 38789029)
69. Min JH, Lee MW, Rhim H, et al. (2011) Recurrent hepatocellular carcinoma after transcatheter arterial chemoembolization: planning sonography for radio frequency ablation. J Ultrasound Med 30:617-624
70. Kim HJ, Kim TK, Kim PN, et al. (2006) Assessment of the therapeutic response of hepatocellular carcinoma treated with transcatheter arterial chemoembolization: comparison of contrast-enhanced sonography and 3-phase computed tomography. J Ultrasound Med 25:477-486
71. Jang HJ, Kim TK, Burns PN, Wilson SR (2007) Enhancement patterns of hepatocellular carcinoma at contrast-enhanced US: comparison with histologic differentiation. Radiology 244:898-906 (Pubitemid 47292103)
72. Minami Y, Kudo M (2009) Contrast-enhanced harmonic ultrasound imaging in ablation therapy for primary hepatocellular carcinoma. World J Radiol 1:86-91
73. Miyamoto N, Hiramatsu K, Tsuchiya K, et al. (2009) Sonazoid-enhanced sonography for guiding radiofrequency ablation for hepatocellular carcinoma: better tumor visualization by Kupffer-phase imaging and vascular-phase imaging after reinjection. Jpn J Radiol 27:185-193
74. Dill-Macky MJ, Asch M, Burns P, Wilson S (2006) Radiofrequency ablation of hepatocellular carcinoma: predicting success using contrast-enhanced sonography. AJR Am J Roentgenol 186:S287-S295 (Pubitemid 46114733)
75. Vilana R, Bianchi L, Varela M, et al. (2006) Is microbubble-enhanced ultrasonography sufficient for assessment of response to percutaneous treatment in patients with early hepatocellular carcinoma? Eur Radiol 16:2454-2462 (Pubitemid 44649694)
76. Nakai M, Sato M, Sahara S, et al. (2009) Radiofrequency ablation assisted by real-time virtual sonography and CT for hepatocellular carcinoma undetectable by conventional sonography. Cardiovasc Intervent Radiol 32:62-69
77. Minami Y, Chung H, Kudo M, et al. (2008) Radiofrequency ablation of hepatocellular carcinoma: value of virtual CT sonography with magnetic navigation. AJR Am J Roentgenol 190:W335-W341 (Pubitemid 351798535)
78. Kitada T, Murakami T, Kuzushita N, et al. (2008) Effectiveness of real-time virtual sonography-guided radiofrequency ablation treatment for patients with hepatocellular carcinomas. Hepatol Res 38:565-571 (Pubitemid 351622282)
79. Tatsugami F, Matsuki M, Nakai G, et al. (2007) Hepatic computed tomography for simultaneous depiction of hepatocellular carcinoma, intrahepatic portal veins, and hepatic veins in real-time virtual sonography: initial experience. J Ultrasound Med 26:1065-1069 (Pubitemid 47221837)
80. Minami Y, Kudo M, Chung H, et al. (2007) Percutaneous radiofrequency ablation of sonographically unidentifiable liver tumors. Feasibility and usefulness of a novel guiding technique with an integrated system of computed tomography and sonographic images. Oncology 72(Suppl 1):111-116 (Pubitemid 350256674)
81. Hirooka M, Iuchi H, Kumagi T, et al. (2006) Virtual sonographic radiofrequency ablation of hepatocellular carcinoma visualized on CT but not on conventional sonography. AJR Am J Roentgenol 186:S255-S260 (Pubitemid 46114728)
82. Lencioni R, Crocetti L, Pina MC, Cioni D (2009) Percutaneous image-guided radiofrequency ablation of liver tumors. Abdom Imaging 34:547-556
83. Liu FY, Yu XL, Liang P, et al. (2011) Microwave ablation assisted by a real-time virtual navigation system for hepatocellular carcinoma undetectable by conventional ultrasonography. Eur J Radiol. doi: 10.1016/j.ejrad.2011.03.057
84. Kawasoe H, Eguchi Y, Mizuta T, et al. (2007) Radiofrequency ablation with the real-time virtual sonography system for treating hepatocellular carcinoma difficult to detect by ultrasonography. J Clin Biochem Nutr 40:66-72 (Pubitemid 46449690)
85. Buckner CA, Venkatesan A, Locklin JK, Wood BJ (2011) Real-time sonography with electromagnetic tracking navigation for biopsy of a hepatic neoplasm seen only on arterial phase computed tomography. J Ultrasound Med 30:253-256
86. Krucker J, Xu S, Venkatesan A, et al. (2011) Clinical utility of real-time fusion guidance for biopsy and ablation. J Vasc Interv Radiol 22:515-524
87. Wood BJ, Kruecker J, Abi-Jaoudeh N, et al. (2010) Navigation systems for ablation. J Vasc Interv Radiol 21:S257-S263