Herpesvirus infections and allergic sensitization in children of families with anthroposophic and non-anthroposophic lifestyle - the ALADDIN birth cohort

Pediatric Allergy and Immunology

Volumn 24, Issue 1, 2013, Pages 61-65

  Hesla, Helena Marell ^a   Gutzeit, Cindy ^a   Stenius, Fredrik ^a   Scheynius, Annika ^a   Dahl, Helena ^b   Linde, Annika ^b   Alm, Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Swedish Institute for Communicable Disease Control   (Sweden)

Author keywords

Anthroposophy; Cytomegalovirus; Epstein Barr virus; HHV6; HHV7; IgE; Infants; Lifestyle; Sensitization; Viral infections

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G;

ALLERGIC DISEASE; ARTICLE; BIRTH; BLOOD SAMPLING; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; EPSTEIN BARR VIRUS; FEMALE; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; INFANT; LIFESTYLE MODIFICATION; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SEROLOGY; SEROPREVALENCE;

ANTHROPOSOPHY; ANTIBODIES, VIRAL; CHILD, PRESCHOOL; COHORT STUDIES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HERPESVIRUS 6, HUMAN; HERPESVIRUS 7, HUMAN; HUMANS; HYPERSENSITIVITY; INFANT; LIFE STYLE; MALE; SEROEPIDEMIOLOGIC STUDIES;

EID: 84872652431     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/pai.12030     Document Type: Article

References (19)

1. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G. Atopy in children of families with an anthroposophic lifestyle. Lancet 1999: 353: 1485-8.
2. Ege MJ, Mayer M, Normand AC, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011: 364: 701-9.
3. Floistrup H, Swartz J, Bergstrom A, et al. Allergic disease and sensitization in Steiner school children. J Allergy Clin Immunol 2006: 117: 59-66.
4. Alfven T, Braun-Fahrlander C, Brunekreef B, et al. Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle-the PARSIFAL study. Allergy 2006: 61: 414-21.
5. von Mutius E. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: farm lifestyles and the hygiene hypothesis. Clin Exp Immunol 2010: 160: 130-5.
6. Nilsson C, Linde A, Montgomery SM, et al. Does early EBV infection protect against IgE sensitization? J Allergy Clin Immunol 2005: 116: 438-44.
7. Veiga RV, Cunha SS, Dattoli VC, et al. Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study. BMC Pulm Med 2011: 11: 24.
8. Calvani M, Alessandri C, Paolone G, Rosengard L, Di Caro A, De Franco D. Correlation between Epstein Barr virus antibodies, serum IgE and atopic disease. Pediatr Allergy Immunol 1997: 8: 91-6.
9. Saghafian-Hedengren S, Sverremark-Ekstrom E, Linde A, Lilja G, Nilsson C. Early-life EBV infection protects against persistent IgE sensitization. J Allergy Clin Immunol 2010: 125: 433-8.
10. Nordstrom I, Rudin A, Adlerberth I, et al. Infection of infants with human herpesvirus type 6 may be associated with reduced allergic sensitization and T-helper type 2 development. Clin Exp Allergy 2010: 40: 882-90.
11. Ward KN. The natural history and laboratory diagnosis of human herpesviruses-6 and -7 infections in the immunocompetent. J Clin Virol 2005: 32: 183-93.
12. Takeuchi K, Tanaka-Taya K, Kazuyama Y, et al. Prevalence of Epstein-Barr virus in Japan: trends and future prediction. Pathol Int 2006: 56: 112-6.
13. Staras SAS, Flanders WD, Dollard SC, Pass RF, McGowan JE Jr, Cannon MJ. Cytomegalovirus seroprevalence and childhood sources of infection: a population-based study among pre-adolescents in the United States. J Clin Virol 2008: 43: 266-71.
14. Stenius F, Swartz J, Lilja G, et al. Lifestyle factors and sensitization in children - the ALADDIN birth cohort. Allergy 2011: 66: 1330-8.
15. Stenius F, Swartz J, Lindblad F, et al. Low salivary cortisol levels in infants of families with an anthroposophic lifestyle. Psychoneuroendocrinology 2010: 35: 1431-7.
16. Linde A, Andersson J, Lundgren G, Wahren B. Subclass reactivity to Epstein-Barr virus capsid antigen in primary and reactivated EBV infections. J Med Virol 1987: 21: 109-21.
17. Linde A, Fridell E, Dahl H, Andersson J, Biberfeld P, Wahren B. Effect of primary Epstein-Barr virus infection on human herpesvirus 6, cytomegalovirus, and measles virus immunoglobulin G titers. J Clin Microbiol 1990: 28: 211-5.
18. Zerr DM, Meier AS, Selke SS, et al. A population-based study of primary human herpesvirus 6 infection. N Engl J Med 2005: 352: 768-76.
19. Morris MC, Edmunds WJ, Hesketh LM, et al. Sero-epidemiological patterns of Epstein-Barr and herpes simplex (HSV-1 and HSV-2) viruses in England and Wales. J Med Virol 2002: 67: 522-7.