메뉴 건너뛰기




Volumn 108, Issue 1, 2013, Pages 139-148

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients

Author keywords

Androgen receptor; biomarker; phosphorylation; prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; CYCLIN DEPENDENT KINASE 1; ROSCOVITINE;

EID: 84872587781     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.480     Document Type: Article
Times cited : (49)

References (30)
  • 1
    • 0025120244 scopus 로고
    • Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
    • Anderson NG, Maller JL, Tonks NK, Sturgill TW (1990) Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343: 651-653.
    • (1990) Nature , vol.343 , pp. 651-653
    • Anderson, N.G.1    Maller, J.L.2    Tonks, N.K.3    Sturgill, T.W.4
  • 2
    • 0037447330 scopus 로고    scopus 로고
    • Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells
    • Bakin RE, Gioeli D, Sikes RA, Bissonette EA, Weber MJ (2003) Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. Cancer Res 63: 1981-1989.
    • (2003) Cancer Res , vol.63 , pp. 1981-1989
    • Bakin, R.E.1    Gioeli, D.2    Sikes, R.A.3    Bissonette, E.A.4    Weber, M.J.5
  • 3
    • 0037310753 scopus 로고    scopus 로고
    • The response of extracellular signal-regulated kinase (ERK) to androgen-induced proliferation in the androgen-sensitive prostate cancer cell line
    • Bell WC, Myers RB, Hosein TO, Oelschlager DK, Grizzle WE (2003) The response of extracellular signal-regulated kinase (ERK) to androgen-induced proliferation in the androgen-sensitive prostate cancer cell line, LNCaP. Biotech Histochem 78: 11-16.
    • (2003) LNCaP. Biotech Histochem , vol.78 , pp. 11-16
    • Bell, W.C.1    Myers, R.B.2    Hosein, T.O.3    Oelschlager, D.K.4    Grizzle, W.E.5
  • 4
    • 0032539993 scopus 로고    scopus 로고
    • Forskolin-induced dephosphorylation of the androgen receptor impairs ligand binding
    • Blok LJ, de Ruiter PE, Brinkmann AO (1998) Forskolin-induced dephosphorylation of the androgen receptor impairs ligand binding. Biochemistry 37: 3850-3857.
    • (1998) Biochemistry , vol.37 , pp. 3850-3857
    • Blok, L.J.1    De Ruiter, P.E.2    Brinkmann, A.O.3
  • 5
    • 84863245741 scopus 로고    scopus 로고
    • Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation
    • Chen S, Gulla S, Cai C, Balk SP (2012) Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation. J Biol Chem 287(11): 8571-8583.
    • (2012) J Biol Chem , vol.287 , Issue.11 , pp. 8571-8583
    • Chen, S.1    Gulla, S.2    Cai, C.3    Balk, S.P.4
  • 6
    • 33750452673 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1
    • Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP (2006) Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Nat Acad Sci USA 103: 15969-15974.
    • (2006) Proc Nat Acad Sci USA , vol.103 , pp. 15969-15974
    • Chen, S.1    Xu, Y.2    Yuan, X.3    Bubley, G.J.4    Balk, S.P.5
  • 7
    • 79551581840 scopus 로고    scopus 로고
    • The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process
    • Chymkowitch P, Le May N, Charneau P, Compe E, Egly JM (2011) The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process. EMBO J 30(3): 468-479.
    • (2011) EMBO J , vol.30 , Issue.3 , pp. 468-479
    • Chymkowitch, P.1    Le May, N.2    Charneau, P.3    Compe, E.4    Egly, J.M.5
  • 8
    • 33846002787 scopus 로고    scopus 로고
    • Variation in the definition of biochemical recurrence in patients treated for localized prostate cancer: The American Urological Association Prostate Guidelines for Localized Prostate Cancer Update Panel report and recommendations for a standard in the reporting of surgical outcomes
    • Cookson MS, Aus G, Burnett AL, Canby-Hagino ED, D'Amico AV, Dmochowski RR, Eton DT, Forman JD, Goldenberg SL, Hernandez J, Higano CS, Kraus SR, Moul JW, Tangen C, Thrasher JB, Thompson I (2007) Variation in the definition of biochemical recurrence in patients treated for localized prostate cancer: the American Urological Association Prostate Guidelines for Localized Prostate Cancer Update Panel report and recommendations for a standard in the reporting of surgical outcomes. J Urol 177: 540-545.
    • (2007) J Urol , vol.177 , pp. 540-545
    • Cookson, M.S.1    Aus, G.2    Burnett, A.L.3    Canby-Hagino, E.D.4    D'Amico, A.V.5    Dmochowski, R.R.6    Eton, D.T.7    Forman, J.D.8    Goldenberg, S.L.9    Hernandez, J.10    Higano, C.S.11    Kraus, S.R.12    Moul, J.W.13    Tangen, C.14    Thrasher, J.B.15    Thompson, I.16
  • 9
    • 42249106022 scopus 로고    scopus 로고
    • Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: Potential implications for prostate cancer development and prognosis
    • Diallo JS, Aldejmah A, Mouhim AF, Fahmy MA, Koumakpayi IH, Sircar K, Begin LR, Mes-Masson AM, Saad F (2008) Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: potential implications for prostate cancer development and prognosis. BJU Int 101: 1302-1309.
    • (2008) BJU Int , vol.101 , pp. 1302-1309
    • Diallo, J.S.1    Aldejmah, A.2    Mouhim, A.F.3    Fahmy, M.A.4    Koumakpayi, I.H.5    Sircar, K.6    Begin, L.R.7    Mes-Masson, A.M.8    Saad, F.9
  • 11
    • 0038275924 scopus 로고    scopus 로고
    • Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis
    • Fu Z, Smith PC, Zhang L, Rubin MA, Dunn RL, Yao Z, Keller ET (2003) Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst 95: 878-889.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 878-889
    • Fu, Z.1    Smith, P.C.2    Zhang, L.3    Rubin, M.A.4    Dunn, R.L.5    Yao, Z.6    Keller, E.T.7
  • 13
    • 84857360697 scopus 로고    scopus 로고
    • Post-translational modification of the androgen receptor
    • Gioeli D, Paschal BM (2012) Post-translational modification of the androgen receptor. Mol Cell Endocrinol 352: 70-78.
    • (2012) Mol Cell Endocrinol , vol.352 , pp. 70-78
    • Gioeli, D.1    Paschal, B.M.2
  • 14
    • 0030611850 scopus 로고    scopus 로고
    • The prognostic significance of p34cdc2 and cyclin D1 protein expression in prostate adenocarcinoma
    • Kallakury BV, Sheehan CE, Ambros RA, Fisher HA, Kaufman Jr RP, Ross JS (1997) The prognostic significance of p34cdc2 and cyclin D1 protein expression in prostate adenocarcinoma. Cancer 80: 753-763.
    • (1997) Cancer , vol.80 , pp. 753-763
    • Kallakury, B.V.1    Sheehan, C.E.2    Ambros, R.A.3    Fisher, H.A.4    Kaufman Jr., R.P.5    Ross, J.S.6
  • 16
    • 0028911066 scopus 로고
    • Phosphotryptic peptide analysis of the human androgen receptor: Detection of a hormone-induced phosphopeptide
    • Kuiper GG, Brinkmann AO (1995) Phosphotryptic peptide analysis of the human androgen receptor: detection of a hormone-induced phosphopeptide. Biochemistry 34: 1851-1857.
    • (1995) Biochemistry , vol.34 , pp. 1851-1857
    • Kuiper, G.G.1    Brinkmann, A.O.2
  • 18
    • 81955164170 scopus 로고    scopus 로고
    • Cancer incidence in the United Kingdom: Projections to the year 2030
    • Mistry M, Parkin DM, Ahmad AS, Sasieni P (2011) Cancer incidence in the United Kingdom: projections to the year 2030. Br J Cancer 105: 1795-1803.
    • (2011) Br J Cancer , vol.105 , pp. 1795-1803
    • Mistry, M.1    Parkin, D.M.2    Ahmad, A.S.3    Sasieni, P.4
  • 20
    • 0042622251 scopus 로고    scopus 로고
    • Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
    • Obenauer JC, Cantley LC, Yaffe MB (2003) Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res 31: 3635-3641.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3635-3641
    • Obenauer, J.C.1    Cantley, L.C.2    Yaffe, M.B.3
  • 21
    • 0032521196 scopus 로고    scopus 로고
    • T-loop deletion of CDC2 from breast cancer tissues eliminates binding to cyclin B1 and cyclin-dependent kinase inhibitor p21
    • Ohta T, Okamoto K, Isohashi F, Shibata K, Fukuda M, Yamaguchi S, Xiong Y (1998) T-loop deletion of CDC2 from breast cancer tissues eliminates binding to cyclin B1 and cyclin-dependent kinase inhibitor p21. Cancer Res 58: 1095-1098.
    • (1998) Cancer Res , vol.58 , pp. 1095-1098
    • Ohta, T.1    Okamoto, K.2    Isohashi, F.3    Shibata, K.4    Fukuda, M.5    Yamaguchi, S.6    Xiong, Y.7
  • 22
    • 51049107084 scopus 로고    scopus 로고
    • Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer
    • Ponguta LA, Gregory CW, French FS, Wilson EM (2008) Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer. J Biol Chem 283: 20989-21001.
    • (2008) J Biol Chem , vol.283 , pp. 20989-21001
    • Ponguta, L.A.1    Gregory, C.W.2    French, F.S.3    Wilson, E.M.4
  • 24
    • 33745184874 scopus 로고    scopus 로고
    • Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: Recommendations of the RTOG-ASTRO Phoenix Consensus Conference
    • Roach 3rd M, Hanks G, Thames Jr. H, Schellhammer P, Shipley WU, Sokol GH, Sandler H (2006) Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys 65: 965-974.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 965-974
    • Roach III, M.1    Hanks, G.2    Thames Jr., H.3    Schellhammer, P.4    Shipley, W.U.5    Sokol, G.H.6    Sandler, H.7
  • 25
    • 67049155478 scopus 로고    scopus 로고
    • Soluble factors derived from stroma activated androgen receptor phosphorylation in human prostate LNCaP cells: Roles of ERK/MAP kinase
    • Shigemura K, Isotani S, Wang R, Fujisawa M, Gotoh A, Marshall FF, Zhau HE, Chung LW (2009) Soluble factors derived from stroma activated androgen receptor phosphorylation in human prostate LNCaP cells: roles of ERK/MAP kinase. Prostate 69: 949-955.
    • (2009) Prostate , vol.69 , pp. 949-955
    • Shigemura, K.1    Isotani, S.2    Wang, R.3    Fujisawa, M.4    Gotoh, A.5    Marshall, F.F.6    Zhau, H.E.7    Chung, L.W.8
  • 26
    • 0034465595 scopus 로고    scopus 로고
    • Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells
    • Tyagi RK, Lavrovsky Y, Ahn SC, Song CS, Chatterjee B, Roy AK (2000) Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells. Mol Endocrinol (Baltimore, MD) 14: 1162-1174.
    • (2000) Mol Endocrinol (Baltimore, MD) , vol.14 , pp. 1162-1174
    • Tyagi, R.K.1    Lavrovsky, Y.2    Ahn, S.C.3    Song, C.S.4    Chatterjee, B.5    Roy, A.K.6
  • 27
    • 0034671668 scopus 로고    scopus 로고
    • HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
    • Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC (2000) HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Res 60: 6841-6845.
    • (2000) Cancer Res , vol.60 , pp. 6841-6845
    • Wen, Y.1    Hu, M.C.2    Makino, K.3    Spohn, B.4    Bartholomeusz, G.5    Yan, D.H.6    Hung, M.C.7
  • 29
    • 0029041681 scopus 로고
    • Identification of three proline-directed phosphorylation sites in the human androgen receptor
    • Zhou ZX, Kemppainen JA, Wilson EM (1995) Identification of three proline-directed phosphorylation sites in the human androgen receptor. Mol Endocrinol Baltimore, MD 9: 605-615.
    • (1995) Mol Endocrinol Baltimore, MD , vol.9 , pp. 605-615
    • Zhou, Z.X.1    Kemppainen, J.A.2    Wilson, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.