Uterine transplantation-a real possibility? the Indianapolis consensus

Human Reproduction

Volumn 28, Issue 2, 2013, Pages 288-291

  Del Priore, Giuseppe ^a   Saso, Srdjan ^b   Meslin, Eric M ^c   Tzakis, Andreas ^d   Brännström, Mats ^e   Clarke, Alex ^f   Vianna, Rodrigo ^a   Sawyer, Renata ^c   Richard Smith, J ^g  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c INDIANA UNIVERSITY   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g QUEEN CHARLOTTE S AND CHELSEA HOSPITAL   (United Kingdom)

Author keywords

female infertility; transplantation; uterus

Indexed keywords

ABSOLUTE UTERINE FACTOR INFERTILITY; ADOPTION; BENEFICENCE; CRYOPRESERVATION; EMBRYO; FEMALE INFERTILITY; GRAFT RECIPIENT; HUMAN; HYSTERECTOMY; INFERTILITY THERAPY; INFORMED CONSENT; JUSTICE; MEDICAL ETHICS; MEDICAL EXPERT; MEDICAL HISTORY; MULTICENTER STUDY (TOPIC); NONHUMAN; OOCYTE; ORGAN TRANSPLANTATION; PATIENT SAFETY; PATIENT SATISFACTION; PATIENT SELECTION; PERSONAL AUTONOMY; PREGNANCY; PSYCHOLOGIC ASSESSMENT; REVIEW; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK FACTOR; SURGICAL TECHNIQUE; TERM BIRTH; UNITED STATES; UTERUS; UTERUS BLEEDING; UTERUS DISEASE; UTERUS MALFORMATION; UTERUS SURGERY; UTERUS TRANSPLANTATION;

EID: 84872584792     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des406     Document Type: Review

References (17)

1. Armenti VT. Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation. Clin Transpl 2010; 65-85.
2. Beauchamp TL, Childress JF. Principles of Biomedical Ethics, 6th edn. New York: Oxford University Press, 2006.
3. Brannstrom M, Wranning CA, Altchek A. Experimental Uterus Transplantation. Hum Reprod Update 2010;16: 329-345.
4. Brannstrom M, Diaz-Garcia C, Hanafy A, Olausson M, Tzakis A. Uterus transplantation: animal research and human possibilities. Fertil Steril 2012;97: 1269-1276.
5. Coscia LA, Constantinescu S, Moritz MJ, Frank AM, Ramirez CB, Maley WR, Doria C, McGrory CH, Daz-Garca C, Akhi SN, Wallin A, Pellicer A, Brannstrom M. First report on fertility after allogeneic uterus transplantation. Acta Obstet Gynecol Scand 2010; 89: 1491-1494.
6. Eraslan S, Hamernik RJ, Hardy JD. Replantation of uterus and ovaries in dogs, with successful pregnancy. Arch Surg 1966;92: 9-12.
7. Fageeh W, Raffa H, Jabbad H, Marzouki A. Transplantation of the human uterus. Int J Gynaecol Obstet 2002;76: 245-251.
8. Lefkowitz A, Edwards M, Balayla J. The Montreal criteria for the ethical feasibility of uterine transplantation. Transpl Int 2012; 25: 439-447.
9. Mihara M, Kisu I, Hara H, Iida T, Araki J, Shim T, Narushima M, Yamamoto T, Moriguchi H, Kato Y et al. Uterine autotransplantation in cynomolgus macaques: the first case of pregnancy and delivery. Hum Reprod 2012;27: 2332-2340.
10. Milliez J. Uterine transplantation FIGO Committee for the Ethical Aspects of Human Reproduction and Women's Health. Int J Gynaecol Obstet 2009;106: 270.
11. Moore FD. Ethical problems special to surgery: surgical teaching, surgical innovation, and the surgeon in managed care. Arch Surg 2000;135: 14-16.
12. Nair A, Stega J, Smith JR, Del Priore G. Uterus transplant. Evidence and ethics. Ann NY Acad Sci 2008;1127: 83-91.
13. Pomahac B, Pribaz J, Eriksson E, Bueno EM, Diaz-Siso JR, Rybicki FJ, Annino DJ, Orgill D, Caterson EJ, Caterson SA et al. Three patients with full facial transplantation. N Engl J Med 2012;366: 715-722.
14. Ramirez ER, Ramirez Nessetti DK, Nessetti MB, Khatamee M, Wolfson MR, Shaffer TH, Ramirez VZ, Ramirez HA. Pregnancy and outcome of uterine allotransplantation and assisted reproduction in sheep. J Minim Invasive Gynecol 2011;18: 238-245.
15. Smith JR, Boyle DC, Corless DJ, Ungar L, Lawson AD, Del Priore G, McCall JM, Lindsay I, Bridges JE. Abdominal radical trachelectomy: a new surgical technique for the conservative management of cervical carcinoma. Br J Obstet Gynaecol 1997;104: 1196-1200.
16. Vianna R, Kubal C, Mangus R, Fridell J, Tector J. Intestinal and multivisceral transplantation at Indiana University: 6 years' experience with 100 cases. Clin Transpl 2009;219-228.
17. Wranning CA, Akhi SN, Diaz-Garcia C, Brannstrom M. Pregnancy after syngeneic uterus transplantation and spontaneous mating in the rat. Hum Reprod 2011;26: 553-558.