Abnormalities in Resting-State Functional Connectivity in Early Human Immunodeficiency Virus Infection

Brain Connectivity

Volumn 1, Issue 3, 2011, Pages 207-217

  Wang, Xue ^a   Foryt, Paul ^a,b   Ochs, Renee ^a   Chung, Jae Hoon ^a,b   wu, Ying ^c   Parrish, Todd ^a   Ragin, Ann B ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Northwestern University   (United States)

^c University Health System   (United States)

Author keywords

early HIV infection; lateral occipital cortex network; resting state functional connectivity

Indexed keywords

EID: 84872502378     PISSN: 21580014     EISSN: 21580022     Source Type: Journal    
DOI: 10.1089/brain.2011.0016     Document Type: Article

References (71)

1. Abou-Elseoud A, Starck T, Remes J, Nikkinen J, Tervonen O, Kiviniemi V. 2010. The effect of model order selection in group PICA. Hum Brain Mapp 31:1207-1216.
2. Ances B.M., Sisti D, Vaida F, Liang C.L., Leontiev O, Perthen J.E., et al. 2009. Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain. Neurology 73:702-708.
3. Antinori A, Arendt G, Becker J.T., Brew B.J., Byrd D.A., Cherner M, et al. 2007. Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69:1789-1799.
4. Beckmann C, Mackay C, Filippini N, Smith S. 2009. Group comparison of resting-state fMRI data using multi-subject ICA and dual regression. FMRIB Centre, Department of Clinical Neurology, University of Oxford, Oxford, United Kingdom. Available at: http://fsl.fmrib.ox.ac.uk/analysis/dualreg/dualreg_poster.pdf Last accessed Sep. 1, 2011.
5. Beckmann C.F., DeLuca M, Devlin J.T., Smith SM. 2005. Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc B Biol Sci 360:1001-1013.
6. Benton A.L., Hamsher KD. 1976. Multilingual Aphasia Examination. University of Iowa, Iowa City.
7. Biswal B, Yetkin F.Z., Haughton V.M., Hyde JS. 1995. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34:537-541.
8. Biswal B.B., Mennes M, Zuo X.N., Gohel S, Kelly C, Smith S.M., et al. 2010. Toward discovery science of human brain function. Proc Natl Acad Sci USA 107:4734-4739.
9. Bruce-Keller A.J., Chauhan A, Dimayuga F.O., Gee J, Keller J.N., Nath A. 2003. Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain. J Neurosci 23:8417-8422.
10. Buckner RL. 2010. Human functional connectivity: new tools, unresolved questions. Proc Natl Acad Sci USA 107:10769-10770.
11. Caspers S, Eickhoff S.B., Geyer S, Scheperjans F, Mohlberg H, Zilles K, et al. 2008. The human inferior parietal lobule in stereotaxic space. Brain Struct Funct 212:481-495.
12. Chen Y, An H, Zhu H, Stone T, Smith J.K., Hall C, et al. 2009. White matter abnormalities revealed by diffusion tensor imaging in non-demented and demented HIV+ patients. Neuroimage 47:1154-1162.
13. Chiang M-C, Dutton R.A., Hayashi K.M., Lopez O.L., Aizenstein H.J., Toga A.W., et al. 2007. 3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometry. Neuroimage 34:44-60.
14. Chiodi F, Albert J, Olausson E, Norkrans G, Hagberg L, Sonnerborg A, et al. 1988. Isolation frequency of human immunodeficiency virus from cerebrospinal fluid and blood of patients with varying severity of HIV infection. AIDS Res Hum Retroviruses 4:351-358.
15. Chiodi F, Fenyo EM. 1991. Neurotropism of human immunodeficiency virus. Brain Pathol 1:185-191.
16. Cole D.M., Smith S.M., Beckmann CF. 2010. Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Front Syst Neurosci 4:8.
17. Cysique L.A., Maruff P, Brew BJ. 2004. Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus-infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: a combined study of two cohorts. J Neurovirol 10:350-357.
18. Damoiseaux J, Greicius M. 2009. Greater than the sum of its parts: a review of studies combining structural connectivity and resting-state functional connectivity. Brain Struct Funct 213:525-533.
19. Davis L.E., Hjelle B.L., Miller V.E., Palmer D.L., Llewellyn A.L., Merlin T.L., et al. 1992. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 42:1736-1739.
20. Ellis R, Langford D, Masliah E. 2007. HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci 8:33-44.
21. Ellis R.J., Calero P, Stockin MD. 2009. HIV infection and the central nervous system: a primer. Neuropsychol Rev 19:144-151.
22. Ellis R.J., Deutsch R, Heaton R.K., Marcotte T.D., McCutchan J.A., Nelson J.A., et al. 1997. Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group. Arch Neurol 54:416-424.
23. Erhardt E.B., Rachakonda S, Bedrick E.J., Allen E.A., Adali T, Calhoun VD. 2010. Comparison of multi-subject ICA methods for analysis of fMRI data. Hum Brain Mapp [Epub ahead of print]; DOI: 10.1002/hbm.21170
24. Everall I.P., Heaton R.K., Marcotte T.D., Ellis R.J., McCutchan J.A., Atkinson J.H., et al. 1999. Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center. Brain Pathol 9:209-217.
25. Filippini N, MacIntosh B.J., Hough M.G., Goodwin G.M., Frisoni G.B., Smith S.M., et al. 2009. Distinct patterns of brain activity in young carriers of the APOE-Ã4 allele. Proc Natl Acad Sci USA 106:7209-7214.
26. Flowers K.A., Robertson C. 1985. The effect of Parkinson's disease on the ability to maintain a mental set. J Neurol Neurosurg Psychiatry 48:517-529.
27. Friston K.J., Frith C.D., Liddle P.F., Frackowiak RS. 1993. Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab 13:5-14.
28. Goldman L, Ausiello D. 2008. Cecil Medicine, 23rd edition. Philadelphia: Elsevier Saunders.
29. Greicius M. 2008. Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol 21:424-430.
30. Jang J.H., Jung W.H., Choi J.S., Choi C.H., Kang D.H., Shin N.Y., et al. 2011. Reduced prefrontal functional connectivity in the default mode network is related to greater psychopathology in subjects with high genetic loading for schizophrenia. Schizophr Res 127:58-65.
31. Jolles D.D., van Buchem M.A., Crone E.A., Rombouts SA. 2010. A comprehensive study of whole-brain functional connectivity in children and young adults. Cereb Cortex 21:385-391.
32. Klove H. 1963. The Medical Clinics of North America. New York: The Medical Clinics of North America.
33. Lindl K.A., Marks D.R., Kolson D.L., Jordan-Sciutto KL. 2010. HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol 5:294-309.
34. Masliah E, Heaton R.K., Marcotte T.D., Ellis R.J., Wiley C.A., Mallory M, et al. 1997. Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol 42:963-972.
35. McArthur J.C., Brew B.J., Nath A. 2005. Neurological complications of HIV infection. Lancet Neurol 4:543-555.
36. Miller E.N., Satz P, Visscher B. 1991. Computerized and conventional neuropsychological assessment of HIV-1-infected homosexual men. Neurology 41:1608-1616.
37. Mohammadi B, Kollewe K, Samii A, Beckmann C.F., Dengler R, Münte TF. 2011. Changes in resting-state brain networks in writer's cramp. Hum Brain Mapp [Epub ahead of print]; DOI: 10.1002/hbm.21250.
38. Moore D.J., Letendre S.L., Morris S, Umlauf A, Deutsch R, Smith D.M., et al. 2011. Neurocognitive functioning in acute or early HIV infection. J Neurovirol 17:50-57.
39. Moore D.J., Masliah E, Rippeth J.D., Gonzalez R, Carey C.L., Cherner M, et al. 2006. Cortical and subcortical neurodegeneration is associated with HIV neurocognitive impairment. AIDS 20:879-887.
40. Nelson C, Luciana M (eds.) 2008. Handbook of Developmental Cognitive Neuroscience, 2nd edition. Cambridge, MA: MIT Press.
41. Nelson H.E., O'Connell A. 1978. Dementia: the estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex 14:234-244.
42. Orenstein J.M., Meltzer M.S., Phipps T, Gendelman HE. 1988. Cytoplasmic assembly and accumulation of human immunodeficiency virus types 1 and 2 in recombinant human colony-stimulating factor-1-treated human monocytes: an ultrastructural study. J Virol 62:2578-2586.
43. Ragin A.B., Storey P, Cohen B.A., Epstein L.G., Edelman RR. 2004. Whole brain diffusion tensor imaging in HIV-associated cognitive impairment. AJNR Am J Neuroradiol 25:195-200.
44. Ragin A.B., Wu Y, Du H, Ochs R, Epstein L, 2011. Injury to the brain is evident early in HIV infection. 18th Conference on Retroviruses and Opportunistic Infections, Boston, MA.
45. Raichle M.E., MacLeod A.M., Snyder A.Z., Powers W.J., Gusnard D.A., Shulman GL. 2001. A default mode of brain function. Proc Natl Acad Sci USA 98:676-682.
46. Rajagovindan R, Ding M. 2008. Decomposing neural synchrony: toward an explanation for near-zero phase-lag in cortical oscillatory networks. PLoS One 3:e3649.
47. Rey A. 1941. L'examen psychologique dans les cas d'encephalopathie traumatique. Arch Psychol 28:286-340.
48. Robertson K.R., Su Z, Margolis D.M., Krambrink A, Havlir D.V., Evans S, et al. 2011. Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort. Neurology 74:1260-1266.
49. Schacker T, Collier A.C., Hughes J, Shea T, Corey L. 1996. Clinical and epidemiologic features of primary HIV infection. [see comment] Ann Intern Med 125:257-264. [erratum appears in Ann Intern Med 1997 Jan 15;126(2):174].
50. Scheperjans F, Palomero-Gallagher N, Grefkes C, Schleicher A, Zilles K. 2005. Transmitter receptors reveal segregation of cortical areas in the human superior parietal cortex: Relations to visual and somatosensory regions. Neuroimage 28:362-379.
51. Schouten E.J., Jahn A, Midiani D, Makombe S.D., Mnthambala A, Chirwa Z, et al. 2011. Prevention of mother-to-child transmission of HIV and the health-related millennium development goals: time for a public health approach. Lancet 378:282-284.
52. Sevigny J.J., Albert S.M., McDermott M.P., McArthur J.C., Sacktor N, Conant K, et al. 2004. Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia. Neurology 63:2084-2090.
53. Sevigny J.J., Albert S.M., McDermott M.P., Schifitto G, McArthur J.C., Sacktor N, et al. 2007. An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection. Arch Neurol 64:97-102.
54. Smith S.M., Fox P.T., Miller K.L., Glahn D.C., Fox P.M., Mackay C.E., et al. 2009. Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci USA 106:13040-13045.
55. Smith S.M., Nichols TE. 2009. Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage 44:83-98.
56. Spreen O, Strauss E. 1998. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary, 2nd ed. New York, NY: Oxford University Press.
57. Stebbins G.T., Smith C.A., Bartt R.E., Kessler H.A., Adeyemi O.M., Martin E, et al. 2007. HIV-associated alterations in normal-appearing white matter: a voxel-wise diffusion tensor imaging study. JAIDS J Acquir Immune Defic Syndr 46:564-573.
58. Stern Y, Andrews H, Pittman J, Sano M, Tatemichi T, Lantigua R, et al. 1992. Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education. Arch Neurol 49:453-460.
59. Tate D, Conley J, Paul R, Coop K, Zhang S, Zhou W, et al. 2010. Quantitative diffusion tensor imaging tractography metrics are associated with cognitive performance among HIV-infected patients. Brain Imaging Behav 4:68-79.
60. Thompson P.M., Dutton R.A., Hayashi K.M., Toga A.W., Lopez O.L., Aizenstein H.J., et al. 2005. Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline. Proc Natl Acad Sci USA 102:15647-15652.
61. Tozzi V, Balestra P, Serraino D, Bellagamba R, Corpolongo A, Piselli P, et al. 2005. Neurocognitive impairment and survival in a cohort of HIV-infected patients treated with HAART. AIDS Res Hum Retroviruses 21:706-713.
62. Wang X, Chen Y, Bressler S.L., Ding M. 2007. Granger causality between multiple interdependent neurobiological time series: blockwise versus pairwise methods. Int J Neural Syst 17:71-78.
63. Wang X, Chen Y, Ding M. 2008. Estimating Granger causality after stimulus onset: a cautionary note. Neuroimage 41:767-776.
64. Wawer M.J., Gray R.H., Sewankambo N.K., Serwadda D, Li X, Laeyendecker O, et al. 2005. Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 191:1403-1409.
65. Wechsler D. 1981. Wechsler Adult Intelligence Scale Revised. New York: The Psychological Corporation.
66. Werner C, Stãcker T, Kellermann T, Wegener H, Schneider F, Shah N, et al. 2010a. Altered amygdala functional connectivity in adult Tourette's syndrome. Eur Arch Psychiatry Clin Neurosci 260:95-99.
67. Werner C.J., Stãcker T, Kellermann T, Bath J, Beldoch M, Schneider F, et al. 2010b. Altered motor network activation and functional connectivity in adult tourette's syndrome. Hum Brain Mapp [Epub ahead of print]; doi: 10.1002/hbm.21175.
68. Woods S, Moore D, Weber E, Grant I. 2009. Cognitive neuropsychology of HIV-associated neurocognitive disorders. Neuropsychol Rev 19:152-168.
69. Zhang Y, Wang X, Bressler S.L., Chen Y, Ding M. 2008. Prestimulus cortical activity is correlated with speed of visuomotor processing. J Cogn Neurosci 20:1915-1925.
70. Zhou J, Greicius M.D., Gennatas E.D., Growdon M.E., Jang J.Y., Rabinovici G.D., et al. 2010. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain 133:1352-1367.
71. Zuo X-N, Kelly C, Adelstein J.S., Klein D.F., Castellanos F.X., Milham MP. 2010. Reliable intrinsic connectivity networks: test-retest evaluation using ICA and dual regression approach. Neuroimage 49:2163-2177.