H2AX and lung cancer: Is it the Ariadne's thread?

DNA Repair

Volumn 12, Issue 2, 2013, Pages 90-91

  Matthaios, D ^a   Bouros, D ^a   Kakolyris, S ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2AX;

CANCER PROGNOSIS; CATALYSIS; DNA DAMAGE; GENE OVEREXPRESSION; HISTONE PHOSPHORYLATION; HUMAN; LETTER; LUNG NON SMALL CELL CANCER; OVERALL SURVIVAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOLID TUMOR;

DNA REPAIR; HISTONES; HUMANS; LUNG NEOPLASMS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84872493359     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.11.003     Document Type: Letter

References (5)

1. American Cancer Society Cancer Facts & Figures 2012.
2. Gorgoulis V.G., Vassiliou L.V., Karakaidos P., et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005, 434:907-913.
3. Matthaios D., Hountis P., Trypsianis G., et al. γ-H2AX as a novel prognostic marker in patients with non-small lung cancer. J. Clin. Oncol. 2012, 30(Suppl.). (abstr. e17553).
4. Postel-Vinay S., Vanhecke E., Olaussen K.A., Lord C.J., Ashwoth A., Soria J.C. The potential of exploiting DNA-repair defects for optimizing lung cancer treatment. Nat. Rev. Clin. Oncol. 2012, 9:144-155.
5. Gazdar A.F. DNA repair and survival in lung cancer-the two faces of Janus. N. Engl. J. Med. 2007, 356:771-773.