Extraction efficacy, stability assessment and seasonal variation of bioactive 'gymnemagenin' in Gymnema sylvestre

Industrial Crops and Products

Volumn 44, Issue , 2013, Pages 572-576

  Manika, N ^a   Singh, Suman ^a   Verma, R K ^a   Bagchi, G D ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

Author keywords

Extraction; Gymnema sylvestre; Gymnemagenin; Seasonal variation; Stability

Indexed keywords

ACID BASE; ANNUAL CYCLE; ANTIDIABETIC ACTIVITY; DRIED LEAVES; DRYING METHODS; EXTRACTION PROCEDURE; GYMNEMA SYLVESTRE; GYMNEMAGENIN; HEALTH BENEFITS; LIGHT CONDITIONS; MEDICINAL PLANTS; NATURAL SOURCES; SEASONAL VARIATION; SOLVENT SELECTION; STABILITY ASSESSMENT; VALORISATION;

CONVERGENCE OF NUMERICAL METHODS; EXTRACTION; PLANT EXTRACTS; POLYSTYRENES; QUALITY ASSURANCE; SOLVENTS;

SYSTEM STABILITY;

ANNUAL CYCLE; BIOACTIVITY; DISEASE TREATMENT; ETHNOBOTANY; HARVESTING; HERB; HYDROLYSIS; LEAF; LIGHT AVAILABILITY; MEDICINAL PLANT; SEASONAL VARIATION;

APOCYNACEAE; GYMNEMA SYLVESTRE;

EID: 84872487970     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2012.09.020     Document Type: Article

References (20)

1. Baskaran K., Kizar A.B., Radha S.K., Shanmugasundaram E.R. Antidiabetic effects of leaf extract from Gymnema sylvestre in non-insulin dependent diabetes mellitus patients. J. Ethnopharmacol. 1990, 30(3):295-300.
2. Carmen W.H. A review of modern sample-preparation techniques for the extraction and analysis of medicinal plants. Anal. Bioanal. Chem. 2002, 373:23-30.
3. Khanna V.G., Kannabiran K., Rajakumar G., Rahuman A.A., Santhoshkumar T. Biolarvicidal compound gymnemagenol isolated from leaf extract of miracle fruit plant, Gymnema sylvestre (Retz) Schult against malaria and filariasis vectors. Parasitol. Res. 2011, 109:1373-1386.
4. Komalavalli N., Rao M.V. In vitro micropropagation of Gymnema sylvestre - a multipurpose medicinal plant. Plant Cell Tiss. Org. Cult. 2000, 61:97-105.
5. Kundu P.K., Chatterjee P.S. Meta analysis of diabecon tablets: efficacy and safety outcomes from 15 clinical trials in diabetes mellitus. Indian J. Clin. Pract. 2010, 20(9):653-659.
6. Malik J.K., Manvi F.V., Alagawadi K.R., Noolvi M. Evaluation of anti-inflammatory activity of Gymnema sylvestre leaves extract in rats. Int. J. Green Pharm. 2008, 2(2):114-115.
7. Masayuki, Toshiyuki Y.M., Masashi K., Yuhao L., Nubotoshi M., Johji Y., Hisash M. Medicinal foodstuffs. (IX1). The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R.Br. (Asclepiadaceae): structures of gymneomosides A and B. Chem. Pharm. Bull. 1997, 45:1671-1676.
8. Mitra S.K., Gopumadhavan S., Muralidhar T.S., Anturlikar S.D., Sujatha M.B. Effect of D-400 herbomineral preparation on lipid profile glycated haemoglobin and glucose tolerance in streptozotocin induced diabetes in rats. Indian J. Exp. Biol. 1995, 33:798-800.
9. Ohmori R., Iwamoto T., Tago M., Takeo T., Unno T., Itakura H. Antioxidant activity of various teas against free radicals and LDL oxidation. Lipids 2005, 40(8):849-853.
10. Omidbaigi R. Effects of sowing method and harvest time on the production of valerian (Valeriana officinalis) and its active substances. Seed Plant J. 1998, 14(1):24-31.
11. Pasha C., Sayeed S., Ali S., Khan Z. Anti salmonella activity of selected medicinal plants. Turk. J. Biol. 2009, 33:59-64.
12. Puratchimani V., Jha S. Standardization of Gymnema sylvestre R.Br. with reference to gymnemagenin by high-performance thin-layer chromatography. Phytochem. Anal. 2004, 15:164-166.
13. Rachh P.R., Rachh M.R., Soniwala M.M., Joshi V.D., Suthar A.P. Effect of Gymnema leaf extracts on UV induced damage on Salmonella typhi. Asian J. Biol. Sci. 2010, 3(1):28-33.
14. Saneja A., Sharma C., Aneja K.R., Pahwa R. Gymnema Sylvestre (Gurmar): a review. Der Pharm. Lett. 2010, 2(1):275-284.
15. Satdive R.K., Abhilash P., Fulzele D.P. Antimicrobial activity of Gymnema sylvestre leaf extract. Fitoterapia 2003, 74(7):699-701.
16. Shanmugasundaram E.R., Rajeswari G., Baskaran K., Rajesh K.B.R., Radha S.K., Kizar A.B. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J. Ethnopharmacol. 1990, 30(3):281-294.
17. Singh A.K., Prahalad S. Evaluation of clinical efficacy of ayurslim on bodyweight, body mass index, lipid profile and skin fold thickness: a phase IV clinical trial. The Antiseptic 2008, 105(5):241-243.
18. Singh R.D., Gopichand Meena R.L., Sharma B., Singh B., Kaul V.K., Ahuja P.S. Seasonal variation of bioactive components in Valeriana jatamansi from Himachal Pradesh, India. Ind. Crops Prod. 2010, 32:292-296.
19. Trivedi P.D., Pundarikshudu K., Shah K. A validated reverse phase liquid chromatographic method for quantification of gymnemagenin in the Gymnema sylvestre R.Br. leaf samples, extract and market formulation. Int. J. Appl. Sci. Eng. 2011, 9(1):25-31.
20. Yoshikawa K., Arihara S., Matsuura K. A new type of antisweet principles occurring in Gymnema sylvestre. Tetrahedron Lett. 1991, 32(6):789-792.