Mechanical and suboptimal pharmacologic prophylaxis and delayed mobilization but not morbid obesity are associated with venous thromboembolism after total knee arthroplasty: A case-control study

Journal of Hospital Medicine

Volumn 7, Issue 9, 2012, Pages 665-671

  Sadeghi, Banafsheh ^a   Romano, Patrick S ^a   Maynard, Gregory ^b   Strater, Amy L ^c   Hensley, Laurie ^c   Cerese, Julie ^c   White, Richard H ^a  

^a School of Medicine   (United States)

^b Division of Hospital Medicine   (United States)

^c University HealthSystem Consortium   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENOXAPARIN; FONDAPARINUX; LOW MOLECULAR WEIGHT HEPARIN; WARFARIN;

ADULT; ARTICLE; BODY MASS; CASE CONTROL STUDY; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOBILIZATION; MORBID OBESITY; PRIORITY JOURNAL; PROPHYLAXIS; RISK FACTOR; TEACHING HOSPITAL; TOTAL KNEE REPLACEMENT; VENOUS THROMBOEMBOLISM;

AGE FACTORS; AGED; ANTICOAGULANTS; ARTHROPLASTY, REPLACEMENT, KNEE; CASE-CONTROL STUDIES; FEMALE; HEPARIN, LOW-MOLECULAR-WEIGHT; HOSPITALS, TEACHING; HUMANS; MALE; MECHANICAL THROMBOLYSIS; MIDDLE AGED; OBESITY, MORBID; POSTOPERATIVE COMPLICATIONS; RISK FACTORS; SEX FACTORS; TIME FACTORS; VENOUS THROMBOEMBOLISM; WALKING; WARFARIN;

EID: 84872420174     PISSN: 15535592     EISSN: 15535606     Source Type: Journal    
DOI: 10.1002/jhm.1962     Document Type: Article

References (43)

1. Bjornara BT, Gudmundsen TE, Dahl OE. Frequency and timing of clinical venous thromboembolism after major joint surgery. J Bone Joint Surg Br. 2006; 88( 3): 386-391.
2. Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th ed). Chest. 2008; 133(6 suppl): 381S-453S.
3. Howie C, Hughes H, Watts AC. Venous thromboembolism associated with hip and knee replacement over a ten-year period: a population-based study. J Bone Joint Surg Br. 2005; 87( 12): 1675-1680.
4. Pellegrini VD Jr, Sharrock NE, Paiement GD, Morris R, Warwick DJ. Venous thromboembolic disease after total hip and knee arthroplasty: current perspectives in a regulated environment. Instr Course Lect. 2008; 57: 637-661.
5. Watanabe H, Sekiya H, Kariya Y, Hoshino Y, Sugimoto H, Hayasaka S. The incidence of venous thromboembolism before and after total knee arthroplasty using 16-row multidetector computed tomography. J Arthroplasty. 2011; 26( 8): 1488-1493.
6. White RH, Romano PS, Zhou H, Rodrigo J, Bargar W. Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty. Arch Intern Med. 1998; 158( 14): 1525-1531.
7. Milbrink J, Bergqvist D. The incidence of symptomatic venous thromboembolic events in orthopaedic surgery when using routine thromboprophylaxis. Vasa. 2008; 37( 4): 353-357.
8. White RH, Sadeghi B, Tancredi DJ, et al. How valid is the ICD-9-CM based AHRQ patient safety indicator for postoperative venous thromboembolism? Med Care. 2009; 47( 12): 1237-1243.
9. Department of Health and Human Services, Centers for Medicare & Medicaid Services. Hospital-Acquired Conditions (HAC) in Acute Inpatient Prospective Payment System (IPPS) Hospitals. Available at: http://www.cms.gov/Medicare/Medicare-Fee-for-Service-payment/HospitalAcqCond/downloads/hacfactsheet.pdf. Accessed September 2012.
10. Parvizi J, Kahl L, Dalsey C. Aggressive anticoagulation after TJA: an evaluation of the ACCP guidelines for thromboprophylaxis. J Long Term Eff Med Implants. 2007; 17( 4): 359-365.
11. Eikelboom J, Karthikeyan G, Fagel N, Hirsh J. American Association of Orthopedic Surgeons and American College of Chest Physicians guidelines for venous thromboembolism prevention in hip and knee arthroplasty differ. What are the implications for clinicians and patients? Chest. 2009; 135( 2): 1512-1520.
12. Jämsen E, Varonen M, Huhtala H, et al. Incidence of prosthetic joint infections after primary knee arthroplasty. J Arthroplasty. 2010; 25( 1): 87-92.
13. Lachiewicz PF. Comparison of ACCP and AAOS guidelines for VTE prophylaxis after total hip and total knee arthroplasty. Orthopedics. 2009; 32(12 suppl): 74-78.
14. Sobieraj-Teague M, Eikelboom JW, Hirsh J. How can we reduce disagreement among guidelines for venous thromboembolism prevention? J Thromb Haemost. 2010; 8( 4): 675-677.
15. Limpus A, Chaboyer W, McDonald E, Thalib L. Mechanical thromboprophylaxis in critically ill patients: a systematic review and meta-analysis. Am J Crit Care. 2006; 15( 4): 402-410; quiz/discussion, 411-412.
16. Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th ed). Chest. 2008; 133(6 suppl): 454S-545S.
17. Altintaş F, Gürbüz H, Erdemli B, et al. Venous thromboembolism prophylaxis in major orthopaedic surgery: a multicenter, prospective, observational study. Acta Orthop Traumatol Turc. 2008; 42( 5): 322-327.
18. Namba RS, Paxton L, Fithian DC, Stone ML. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty. 2005; 20(suppl 3): 46-50.
19. White RH, Henderson MC. Risk factors for venous thromboembolism after total hip and knee replacement surgery. Curr Opin Pulm Med. 2002; 8( 5): 365-371.
20. Simone E, Madan A, Tichansky D, Kuhl D, Lee M. Comparison of two low-molecular-weight heparin dosing regimens for patients undergoing laparoscopic bariatric surgery. Surg Endosc. 2008; 22( 11): 2392-2395.
21. Rowan B, Kuhl D, Lee M, Tichansky D, Madan A. Anti-Xa levels in bariatric surgery patients receiving prophylactic enoxaparin. Obes Surg. 2008; 18( 2): 162-166.
22. Samama CM, Ravaud P, Parent F, Barre J, Mertl P, Mismetti P. Epidemiology of venous thromboembolism after lower limb arthroplasty: the FOTO study. J Thromb Haemost. 2007; 5( 12): 2360-2367.
23. White RH, Zhou H, Romano PS. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost. 2003; 90( 3): 446-455.
24. White RH. The epidemiology of venous thromboembolism. Circulation. 2003; 107(23 suppl 1): I4-I8.
25. Falck-Ytter Y, Francis CW, Johanson NA, et al. Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141(2 suppl): e278S-e325S.
26. Blanchard J, Meuwly J-Y, Leyvraz P-F, et al. Prevention of deep-vein thrombosis after total knee replacement: randomised comparison between a low-molecular-weight heparin and mechanical prophylaxis with a foot-pump system. J Bone Joint Surg Br. 1999; 81-B( 4): 654-659.
27. AAOS. Pulmonary Embolism After Knee Arthroscopy: Rare but Serious. American Academy of Orthopaedic Surgeons/American Association of Orthopaedic Surgeons Web site. Available at: http://www6aaosorg/news/pemr/releases/releasecfm?releasenum=9692011.
28. Eikelboom JW, Karthikeyan G, Fagel N, Hirsh J. American Association of Orthopedic Surgeons and American College of Chest Physicians guidelines for venous thromboembolism prevention in hip and knee arthroplasty differ: what are the implications for clinicians and patients? Chest. 2009; 135( 2): 513-520.
29. Premier-A supporting partnership organization of the Surgical Care Improvement Project (SCIP). Premier Inc Web site. Available at: http://www.premierinc.com/safety/topics/scip/. Accessed April 10, 2012.
30. Chandrasekaran S, Ariaretnam SK, Tsung J, Dickison D. Early mobilization after total knee replacement reduces the incidence of deep venous thrombosis. Aust N Z J Surg. 2009; 79( 7-8): 526-529.
31. White RH, Gettner S, Newman JM, Trauner KB, Romano PS. Predictors of rehospitalization for symptomatic venous thromboembolism after total hip arthroplasty. N Engl J Med. 2000; 343( 24): 1758-1764.
32. Barrett J, Baron JA, Losina E, Wright J, Mahomed NN, Katz JN. Bilateral total knee replacement: staging and pulmonary embolism. J Bone Joint Surg Am. 2006; 88( 10): 2146-2151.
33. Kim YH, Kim JS. Incidence and natural history of deep-vein thrombosis after total knee arthroplasty. A prospective, randomised study. J Bone Joint Surg Br. 2002; 84( 4): 566-570.
34. Memtsoudis SG, Gonzalez Della Valle A, Besculides MC, Gaber L, Sculco TP. In-hospital complications and mortality of unilateral, bilateral, and revision TKA: based on an estimate of 4, 159, 661 discharges. Clin Orthop Relat Res. 2008; 466( 11): 2617-2627.
35. Restrepo C, Parvizi J, Dietrich T, Einhorn TA. Safety of simultaneous bilateral total knee arthroplasty. A meta-analysis. J Bone Joint Surg Am. 2007; 89( 6): 1220-1226.
36. Dushey CH, Bornstein LJ, Alexiades MM, Westrich GH. Short-term coagulation complications following total knee arthroplasty: a comparison of patient-reported and surgeon-verified complication rates. J Arthroplasty. 2011 Jan 20.
37. Baser O, Supina D, Sengupta N, Wang L, Kwong L. Clinical and cost outcomes of venous thromboembolism in Medicare patients undergoing total hip replacement or total knee replacement surgery. Curr Med Res Opin. 2011; 27( 2): 423-429.
38. Hagen TP, Vaughan-Sarrazin MS, Cram P. Relation between hospital orthopaedic specialisation and outcomes in patients aged 65 and older: retrospective analysis of US Medicare data. BMJ. 2010; 340: c165.
39. Amin A, Stemkowski S, Lin J, Yang G. Thromboprophylaxis rates in US medical centers: success or failure? J Thromb Haemost. 2007; 5( 8): 1610-1616.
40. Knapp RM. Quality and safety performance in teaching hospitals. Am Surg. 2006; 72( 11): 1051-1054; discussion 1061-1059, 1133-1048.
41. Pardini-Kiely K, Greenlee E, Hopkins J, Szaflarski NL, Tabb K. Improving and sustaining core measure performance through effective accountability of clinical microsystems in an academic medical center. Jt Comm J Qual Patient Saf. 2010; 36( 9): 387-398.
42. Fabi DW, Mohan V, Goldstein WM, Dunn JH, Murphy BP. Unilateral vs bilateral total knee arthroplasty risk factors increasing morbidity. J Arthroplasty. 2011; 26( 5): 668-673.
43. Powell RS, Pulido P, Tuason MS, Colwell CW Jr, Ezzet KA. Bilateral vs unilateral total knee arthroplasty: a patient-based comparison of pain levels and recovery of ambulatory skills. J Arthroplasty. 2006; 21( 5): 642-649.