Increased amount of bone marrow-derived smooth muscle-like cells and accelerated atherosclerosis in diabetic apoE-deficient mice

Atherosclerosis

Volumn 226, Issue 2, 2013, Pages 341-347

  Fledderus, J O ^a   van Oostrom, O ^a   de Kleijn, D P V ^a,b   den Ouden, K ^a   Penders, A F ^a   Gremmels, H ^a   de Bree, P ^a   Verhaar, M C ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Atherosclerosis; Bone marrow; Diabetes; Smooth muscle like cells

Indexed keywords

APOLIPOPROTEIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL COUNT; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETES MELLITUS; IN VITRO STUDY; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; SMOOTH MUSCLE FIBER; SPLEEN CELL; WHOLE BODY RADIATION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; DIABETES MELLITUS, EXPERIMENTAL; MALE; MICE; MICE, TRANSGENIC; MYOCYTES, SMOOTH MUSCLE; PLAQUE, ATHEROSCLEROTIC;

EID: 84872418884     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.11.017     Document Type: Article

References (30)

1. Preis S.R., Hwang S.J., Coady S., et al. Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005. Circulation 2009, 119:1728-1735.
2. Uusitupa M.I., Niskanen L.K., Siitonen O., Voutilainen E., Pyorala K. 5-year incidence of atherosclerotic vascular disease in relation to general risk factors, insulin level, and abnormalities in lipoprotein composition in non-insulin-dependent diabetic and nondiabetic subjects. Circulation 1990, 82:27-36.
3. Pandolfi A., Grilli A., Cilli C., et al. Phenotype modulation in cultures of vascular smooth muscle cells from diabetic rats: association with increased nitric oxide synthase expression and superoxide anion generation. J Cell Physiol 2003, 196:378-385.
4. Suzuki L.A., Poot M., Gerrity R.G., Bornfeldt K.E. Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis: lack of direct growth-promoting effects of high glucose levels. Diabetes 2001, 50:851-860.
5. Tanaka K., Sata M., Hirata Y., Nagai R. Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries. Circ Res 2003, 93:783-790.
6. Sata M., Saiura A., Kunisato A., et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002, 8:403-409.
7. Shimizu K., Sugiyama S., Aikawa M., et al. Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy. Nat Med 2001, 7:738-741.
8. Albiero M., Menegazzo L., Fadini G.P. Circulating smooth muscle progenitors and atherosclerosis. Trends Cardiovasc Med 2010, 20:133-140.
9. Bentzon J.F., Falk E. Circulating smooth muscle progenitor cells in atherosclerosis and plaque rupture: current perspective and methods of analysis. Vascul Pharmacol 2010, 52:11-20.
10. Bentzon J.F., Weile C., Sondergaard C.S., Hindkjaer J., Kassem M., Falk E. Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice. Arterioscler Thromb Vasc Biol 2006, 26:2696-2702.
11. Hu Y., Davison F., Ludewig B., et al. Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells. Circulation 2002, 106:1834-1839.
12. Iwata H., Manabe I., Fujiu K., et al. Bone marrow-derived cells contribute to vascular inflammation but do not differentiate into smooth muscle cell lineages. Circulation 2010, 122:2048-2057.
13. Daniel J.M., Bielenberg W., Stieger P., Weinert S., Tillmanns H., Sedding D.G. Time-course analysis on the differentiation of bone marrow-derived progenitor cells into smooth muscle cells during neointima formation. Arterioscler Thromb Vasc Biol 2010, 30:1890-1896.
14. Yu H., Stoneman V., Clarke M., et al. Bone marrow-derived smooth muscle-like cells are infrequent in advanced primary atherosclerotic plaques but promote atherosclerosis. Arterioscler Thromb Vasc Biol 2011, 31:1291-1299.
15. Loomans C.J., de Koning E.J., Staal F.J., et al. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 2004, 53:195-199.
16. Fadini G.P., Avogaro A. It is all in the blood: the multifaceted contribution of circulating progenitor cells in diabetic complications. Exp Diabetes Res 2012, 2012:742976.
17. Sugiyama S., Kugiyama K., Nakamura S., et al. Characterization of smooth muscle-like cells in circulating human peripheral blood. Atherosclerosis 2006, 187:351-362.
18. Wang C.H., Lee Y.S., Lin S.J., et al. Surface markers of heterogeneous peripheral blood-derived smooth muscle progenitor cells. Arterioscler Thromb Vasc Biol 2012, 32:1875-1883.
19. van Ark J., Moser J., Lexis C.P., et al. Type 2 diabetes mellitus is associated with an imbalance in circulating endothelial and smooth muscle progenitor cell numbers. Diabetologia 2012, 55:2501-2512.
20. Nguyen T.Q., Chon H., van Nieuwenhoven F.A., Braam B., Verhaar M.C., Goldschmeding R. Myofibroblast progenitor cells are increased in number in patients with type 1 diabetes and express less bone morphogenetic protein 6: a novel clue to adverse tissue remodelling?. Diabetologia 2006, 49:1039-1048.
21. Westerweel P.E., van Velthoven C.T., Nguyen T.Q., et al. Modulation of TGF-β/BMP-6 expression and increased levels of circulating smooth muscle progenitor cells in a type I diabetes mouse model. Cardiovasc Diabetol 2010, 9:55.
22. Zernecke A., Schober A., Bot I., et al. SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells. Circ Res 2005, 96:784-791.
23. Zoll J., Fontaine V., Gourdy P., et al. Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition. Cardiovasc Res 2008, 77:471-480.
24. Fadini G.P., Albiero M., Menegazzo L., de Kreutzenberg S.V., Avogaro A. The increased dipeptidyl peptidase-4 activity is not counteracted by optimized glucose control in type 2 diabetes, but is lower in metformin-treated patients. Diabetes Obes Metab 2012, 14:518-522.
25. Fadini G.P., Tjwa M. A role for TGF-beta in transforming endothelial progenitor cells into neointimal smooth muscle cells. Atherosclerosis 2010, 211:32-35.
26. Imamura H., Ohta T., Tsunetoshi K., et al. Transdifferentiation of bone marrow-derived endothelial progenitor cells into the smooth muscle cell lineage mediated by tansforming growth factor-beta1. Atherosclerosis 2010, 211:114-121.
27. Moonen J.R., Krenning G., Brinker M.G., Koerts J.A., van Luyn M.J., Harmsen M.C. Endothelial progenitor cells give rise to pro-angiogenic smooth muscle-like progeny. Cardiovasc Res 2010, 86:506-515.
28. Peterson M.C. Circulating transforming growth factor beta-1: a partial molecular explanation for associations between hypertension, diabetes, obesity, smoking and human disease involving fibrosis. Med Sci Monit 2005, 11:RA229-RA232.
29. Pham Y., Tu Y., Wu T., et al. Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-beta in a murine diabetic model of atherosclerosis. Diabetologia 2010, 53:170-179.
30. Linton M.F., Atkinson J.B., Fazio S. Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995, 267:1034-1037.