A new quantitative method to determine the uptake of SPIONs in animal tissue and its application to determine the quantity of nanoparticles in the liver and lung of Balb-c mice exposed to the SPIONs

Journal of Biomedical Nanotechnology

Volumn 9, Issue 1, 2013, Pages 142-145

  Zysler, R D ^a   Lima, E ^a   Mansilla, M Vasquez ^a   Troiani, H E ^a   Pisciotti, M L Mojica ^a   Gurman, P ^b   Lamagna, A ^b   Colombo, L ^c  

^a CENTRO ATÓMICO BARILOCHE   (Argentina)

^b CENTRO ATÓMICO CONSTITUYENTES   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Magnetic Nanoparticles; SPIONs Quantification; Superparamagnetism

Indexed keywords

BIOLOGICAL ORGANS; MAGNETITE; MAGNETITE NANOPARTICLES; MAMMALS; METAL IONS; NANOMAGNETICS; TISSUE;

ANIMAL TISSUE; BALB/C MICE; EXPOSED TO; ITS APPLICATIONS; LUNG TISSUE; MAGNETIZATION MEASUREMENTS; QUANTITATIVE METHOD; SPION QUANTIFICATION; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; TISSUE SAMPLES;

SUPERPARAMAGNETISM;

MAGNETITE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER; LUNG; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; QUANTITATIVE ANALYSIS;

EID: 84872410921     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1467     Document Type: Article

References (9)

1. J. Riemer, H. H. Hoepken, H. Czerwinska, S. R. Robinson, and R. Dringen, Colorimetric ferrozine-based assay for the quantization of iron in culture cells. Anal. Biochem. 331, 370 (2004).
2. J. A. Frank, H. Kalish, S. A. Anderson, E. K. Jordan, E. Pawelczyk, and A. S. Arbab, Color transformation and fluorescence of Prussian blue positive cells: Implications for histological verification of cells labeled with superparamagnetic iron oxide nanoparticles. Mol. Imaging 3, 212 (2007).
3. A. Stroh, C. Faber, T. Neuberger, P. Lorenz, K. Sieland, P. M. Jakob, A. Webb, H. Pilgrimm, R. Schober, E. E. Pohl, and C. Zimmer, In vivo detection limits of magnetically labeled embryonic stem cells in the rat brain using high-field (17.6 T) magnetic resonance imaging. Neuro Image 24, 635 (2005).
4. B. Chertok, A. J. Cole, A. E. David, and V. V. Yang, Comparison of electron spin resonance spectroscopy and plasma inductively-coupled plasma optical emission spectroscopy for biodistribution analysis of iron oxide nanoparticles. Mol. Pharmaceutics 7, 375 (2010).
5. A. Bjørnerud, L. O. Johansson, K. Briley-Saebø, and H. K. Ahlström, Assessment of T 1 and T 2 effects in vivo and ex vivo using iron oxide nanoparticles in steady state-dependence in blood volume and water exchange. Magn. Reson. Med. 47, 461 (2002).
6. L. F. Gamarra, A. J. da Costa-Filho, J. B. Mamani, R. de Cassia Ruiz, L. F Pavon, T. T. Sibov, E. D. Vieira, A. C. Silva, W. M. Pontuschka, and E. Amaro, Jr, Ferromagnetic resonance for the quantification of superparamagnetic iron oxide nanoparticles in biological materials. Int. J. Nanomedicine 5, 203 (2010).
7. S. Sun, H. Zeng, D. B. Robinson, S. Raoux, P. M. Rice, S. X. Wang, and G. Li, Monodisperse MFe2O4 (M = Fe, Co, Mn) nanoparticles. J. Am. Chem. Soc. 126, 273 (2004).
8. J. M. Vargas and R. D. Zysler, Tailoring the size in colloidal iron oxide magnetic nanoparticles. Nanotechnol. 16, 1474 (2005).
9. R. Hergt, R. Hiergeist, I. Hilger, W. A. Kaiser, Y. Lapatnikov, S. Margel, and U. Richter, Tailoring the size in colloidal iron oxide magnetic nanoparticles. J. Magn. Magn. Mater. 270, 345 (2004).