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Volumn 226, Issue 2, 2013, Pages 459-465

Proprotein convertase subtilisin-kexin type 9 is elevated in proteinuric subjects: Relationship with lipoprotein response to antiproteinuric treatment

Author keywords

Antiproteinuric treatment; Chronic kidney disease; LDL cholesterol; Non HDL cholesterol; Proprotein convertase subtilisin kexin type 9; Proteinuria

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROCHLOROTHIAZIDE PLUS LISINOPRIL; LIPOPROTEIN; LISINOPRIL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; SERINE PROTEINASE; SODIUM; UNCLASSIFIED DRUG;

EID: 84872409052     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.11.009     Document Type: Article
Times cited : (45)

References (30)
  • 1
    • 0025150632 scopus 로고
    • Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome
    • Joven J., Villabona C., Vilella E., Masana L., Alberti R., Valles M. Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome. N Engl J Med 1990, 323(9):579-584.
    • (1990) N Engl J Med , vol.323 , Issue.9 , pp. 579-584
    • Joven, J.1    Villabona, C.2    Vilella, E.3    Masana, L.4    Alberti, R.5    Valles, M.6
  • 2
    • 0027232278 scopus 로고
    • Role of elevated lecithin: cholesterol acyltransferase and cholesteryl ester transfer protein activities in abnormal lipoproteins from proteinuric patients
    • Dullaart R.P.F., Gansevoort R.T., Dikkeschei B.D., de Zeeuw D., de Jong P.E., Van Tol A. Role of elevated lecithin: cholesterol acyltransferase and cholesteryl ester transfer protein activities in abnormal lipoproteins from proteinuric patients. Kidney Int 1993, 44(1):91-97.
    • (1993) Kidney Int , vol.44 , Issue.1 , pp. 91-97
    • Dullaart, R.P.F.1    Gansevoort, R.T.2    Dikkeschei, B.D.3    de Zeeuw, D.4    de Jong, P.E.5    Van Tol, A.6
  • 3
    • 67649583547 scopus 로고    scopus 로고
    • Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin
    • Krikken J.A., Waanders F., Dallinga-Thie G.M., et al. Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin. Expert Opin Ther Targets 2009, 13(5):497-504.
    • (2009) Expert Opin Ther Targets , vol.13 , Issue.5 , pp. 497-504
    • Krikken, J.A.1    Waanders, F.2    Dallinga-Thie, G.M.3
  • 4
    • 30344465325 scopus 로고    scopus 로고
    • Cellular cholesterol efflux to plasma from proteinuric patients is elevated and remains unaffected by antiproteinuric treatment
    • Vogt L., Laverman G.D., Van Tol A., Groen A.K., Navis G., Dullaart R.P.F. Cellular cholesterol efflux to plasma from proteinuric patients is elevated and remains unaffected by antiproteinuric treatment. Nephrol Dial Transplant 2006, 21(1):101-106.
    • (2006) Nephrol Dial Transplant , vol.21 , Issue.1 , pp. 101-106
    • Vogt, L.1    Laverman, G.D.2    Van Tol, A.3    Groen, A.K.4    Navis, G.5    Dullaart, R.P.F.6
  • 5
    • 78651061813 scopus 로고    scopus 로고
    • Apolipoprotein B/A-I and total cholesterol/high-density lipoprotein cholesterol ratios both predict cardiovascular events in the general population independently of nonlipid risk factors, albuminuria and C-reactive protein
    • Kappelle P.J.W.H., Gansevoort R.T., Hillege J.L., Wolffenbuttel B.H., Dullaart R.P.F. Apolipoprotein B/A-I and total cholesterol/high-density lipoprotein cholesterol ratios both predict cardiovascular events in the general population independently of nonlipid risk factors, albuminuria and C-reactive protein. J Intern Med 2011, 269(2):232-242.
    • (2011) J Intern Med , vol.269 , Issue.2 , pp. 232-242
    • Kappelle, P.J.W.H.1    Gansevoort, R.T.2    Hillege, J.L.3    Wolffenbuttel, B.H.4    Dullaart, R.P.F.5
  • 6
    • 0347917086 scopus 로고    scopus 로고
    • Lipid management in the proteinuric patient: do not overlook the importance of proteinuria reduction
    • Vogt L., Laverman G.D., Dullaart R.P., Navis G. Lipid management in the proteinuric patient: do not overlook the importance of proteinuria reduction. Nephrol Dial Transplant 2004, 19(1):5-8.
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.1 , pp. 5-8
    • Vogt, L.1    Laverman, G.D.2    Dullaart, R.P.3    Navis, G.4
  • 7
    • 0027226186 scopus 로고
    • The increased risk of coronary heart disease associated with nephrotic syndrome
    • Ordonez J.D., Hiatt R.A., Killebrew E.J., Fireman B.H. The increased risk of coronary heart disease associated with nephrotic syndrome. Kidney Int 1993, 44(3):638-642.
    • (1993) Kidney Int , vol.44 , Issue.3 , pp. 638-642
    • Ordonez, J.D.1    Hiatt, R.A.2    Killebrew, E.J.3    Fireman, B.H.4
  • 8
    • 0029785877 scopus 로고    scopus 로고
    • Down-regulation of hepatic LDL receptor expression in experimental nephrosis
    • Vaziri N.D., Liang K.H. Down-regulation of hepatic LDL receptor expression in experimental nephrosis. Kidney Int 1996, 50(3):887-893.
    • (1996) Kidney Int , vol.50 , Issue.3 , pp. 887-893
    • Vaziri, N.D.1    Liang, K.H.2
  • 10
    • 0025783752 scopus 로고
    • Metabolism of apolipoprotein B-containing lipoproteins in subjects with nephrotic-range proteinuria
    • Warwick G.L., Packard C.J., Demant T., Bedford D.K., Boulton-Jones J.M., Shepherd J. Metabolism of apolipoprotein B-containing lipoproteins in subjects with nephrotic-range proteinuria. Kidney Int 1991, 40(1):129-138.
    • (1991) Kidney Int , vol.40 , Issue.1 , pp. 129-138
    • Warwick, G.L.1    Packard, C.J.2    Demant, T.3    Bedford, D.K.4    Boulton-Jones, J.M.5    Shepherd, J.6
  • 11
    • 0031979035 scopus 로고    scopus 로고
    • Increased VLDL in nephrotic patients results from a decreased catabolism while increased LDL results from increased synthesis
    • de Sain-van der Velden M.G., Kaysen G.A., Barrett H.A., et al. Increased VLDL in nephrotic patients results from a decreased catabolism while increased LDL results from increased synthesis. Kidney Int 1998, 53(4):994-1001.
    • (1998) Kidney Int , vol.53 , Issue.4 , pp. 994-1001
    • de Sain-van der Velden, M.G.1    Kaysen, G.A.2    Barrett, H.A.3
  • 12
    • 66349126280 scopus 로고    scopus 로고
    • PCSK9: a convertase that coordinates LDL catabolism
    • Horton J.D., Cohen J.C., Hobbs H.H. PCSK9: a convertase that coordinates LDL catabolism. J Lipid Res 2009, (Suppl. 50):S172-S177.
    • (2009) J Lipid Res , Issue.SUPPL. 50
    • Horton, J.D.1    Cohen, J.C.2    Hobbs, H.H.3
  • 13
    • 34248366942 scopus 로고    scopus 로고
    • Unravelling the functional significance of PCSK9
    • Lambert G. Unravelling the functional significance of PCSK9. Curr Opin Lipidol 2007, 18(3):304-309.
    • (2007) Curr Opin Lipidol , vol.18 , Issue.3 , pp. 304-309
    • Lambert, G.1
  • 14
    • 70449732531 scopus 로고    scopus 로고
    • Plasma proprotein convertase subtilisin/kexin type 9: a marker of LDL apolipoprotein B-100 catabolism?
    • Chan D.C., Lambert G., Barrett P.H., Rye K.A., Ooi E.M., Watts G.F. Plasma proprotein convertase subtilisin/kexin type 9: a marker of LDL apolipoprotein B-100 catabolism?. Clin Chem 2009, 55(11):2049-2052.
    • (2009) Clin Chem , vol.55 , Issue.11 , pp. 2049-2052
    • Chan, D.C.1    Lambert, G.2    Barrett, P.H.3    Rye, K.A.4    Ooi, E.M.5    Watts, G.F.6
  • 15
    • 79151476997 scopus 로고    scopus 로고
    • Relationship of plasma apolipoprotein M with proprotein convertase subtilisin-kexin type 9 levels in non-diabetic subjects
    • Kappelle P.J.W.H., Lambert G., Dahlback B., Nielsen L.B., Dullaart R.P. Relationship of plasma apolipoprotein M with proprotein convertase subtilisin-kexin type 9 levels in non-diabetic subjects. Atherosclerosis 2011, 214(2):492-494.
    • (2011) Atherosclerosis , vol.214 , Issue.2 , pp. 492-494
    • Kappelle, P.J.W.H.1    Lambert, G.2    Dahlback, B.3    Nielsen, L.B.4    Dullaart, R.P.5
  • 17
    • 44849086762 scopus 로고    scopus 로고
    • Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment
    • Lambert G., Ancellin N., Charlton F., et al. Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment. Clin Chem 2008, 54(6):1038-1045.
    • (2008) Clin Chem , vol.54 , Issue.6 , pp. 1038-1045
    • Lambert, G.1    Ancellin, N.2    Charlton, F.3
  • 19
    • 79961214888 scopus 로고    scopus 로고
    • Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial
    • Slagman M.C., Waanders F., Hemmelder M.H., et al. Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial. BMJ 2011, 343:d4366.
    • (2011) BMJ , vol.343
    • Slagman, M.C.1    Waanders, F.2    Hemmelder, M.H.3
  • 20
    • 65649142017 scopus 로고    scopus 로고
    • A new equation to estimate glomerular filtration rate
    • Levey A.S., Stevens L.A., Schmid C.H., et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009, 150(9):604-612.
    • (2009) Ann Intern Med , vol.150 , Issue.9 , pp. 604-612
    • Levey, A.S.1    Stevens, L.A.2    Schmid, C.H.3
  • 21
    • 84860735288 scopus 로고    scopus 로고
    • Plasma PCSK9 levels and clinical outcomes in the TNT (treating to new targets) trial: a nested case-control study
    • Huijgen R., Boekholdt S.M., Arsenault B.J., et al. Plasma PCSK9 levels and clinical outcomes in the TNT (treating to new targets) trial: a nested case-control study. J Am Coll Cardiol 2012, 59(20):1778-1784.
    • (2012) J Am Coll Cardiol , vol.59 , Issue.20 , pp. 1778-1784
    • Huijgen, R.1    Boekholdt, S.M.2    Arsenault, B.J.3
  • 22
    • 44049101711 scopus 로고    scopus 로고
    • Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan
    • Vogt L., Waanders F., Boomsma F., de Zeeuw D., Navis G. Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan. J Am Soc Nephrol 2008, 19(5):999-1007.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.5 , pp. 999-1007
    • Vogt, L.1    Waanders, F.2    Boomsma, F.3    de Zeeuw, D.4    Navis, G.5
  • 23
    • 0036419739 scopus 로고    scopus 로고
    • Dual renin-angiotensin system blockade at optimal doses for proteinuria
    • Laverman G.D., Navis G., Henning R.H., de Jong P.E., de Zeeuw D. Dual renin-angiotensin system blockade at optimal doses for proteinuria. Kidney Int 2002, 62(3):1020-1025.
    • (2002) Kidney Int , vol.62 , Issue.3 , pp. 1020-1025
    • Laverman, G.D.1    Navis, G.2    Henning, R.H.3    de Jong, P.E.4    de Zeeuw, D.5
  • 24
    • 77956230636 scopus 로고    scopus 로고
    • Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients
    • Costet P., Hoffmann M.M., Cariou B., Guyomarc'h D.B., Konrad T., Winkler K. Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients. Atherosclerosis 2010, 212(1):246-251.
    • (2010) Atherosclerosis , vol.212 , Issue.1 , pp. 246-251
    • Costet, P.1    Hoffmann, M.M.2    Cariou, B.3    Guyomarc'h, D.B.4    Konrad, T.5    Winkler, K.6
  • 25
    • 38949109659 scopus 로고    scopus 로고
    • Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9
    • Careskey H.E., Davis R.A., Alborn W.E., Troutt J.S., Cao G., Konrad R.J. Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9. J Lipid Res 2008, 49(2):394-398.
    • (2008) J Lipid Res , vol.49 , Issue.2 , pp. 394-398
    • Careskey, H.E.1    Davis, R.A.2    Alborn, W.E.3    Troutt, J.S.4    Cao, G.5    Konrad, R.J.6
  • 26
    • 84859229819 scopus 로고    scopus 로고
    • Plasma lipoprotein-associated phospholipase A(2) is inversely correlated with proprotein convertase subtilisin-kexin type 9
    • Constantinides A., Kappelle P.J.W.H., Lambert G., Dullaart R.P.F. Plasma lipoprotein-associated phospholipase A(2) is inversely correlated with proprotein convertase subtilisin-kexin type 9. Arch Med Res 2012, 43(1):11-14.
    • (2012) Arch Med Res , vol.43 , Issue.1 , pp. 11-14
    • Constantinides, A.1    Kappelle, P.J.W.H.2    Lambert, G.3    Dullaart, R.P.F.4
  • 27
    • 22344458137 scopus 로고    scopus 로고
    • Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis
    • Wanner C., Krane V., Marz W., et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 2005, 353(3):238-248.
    • (2005) N Engl J Med , vol.353 , Issue.3 , pp. 238-248
    • Wanner, C.1    Krane, V.2    Marz, W.3
  • 28
    • 63849163945 scopus 로고    scopus 로고
    • Rosuvastatin and cardiovascular events in patients undergoing hemodialysis
    • Fellstrom B.C., Jardine A.G., Schmieder R.E., et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 2009, 360(14):1395-1407.
    • (2009) N Engl J Med , vol.360 , Issue.14 , pp. 1395-1407
    • Fellstrom, B.C.1    Jardine, A.G.2    Schmieder, R.E.3
  • 29
    • 79959746706 scopus 로고    scopus 로고
    • The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
    • Baigent C., Landray M.J., Reith C., et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet 2011, 377(9784):2181-2192.
    • (2011) Lancet , vol.377 , Issue.9784 , pp. 2181-2192
    • Baigent, C.1    Landray, M.J.2    Reith, C.3
  • 30
    • 84858638369 scopus 로고    scopus 로고
    • Effect of a monoclonal antibody to PCSK9 on LDL cholesterol
    • Stein E.A., Mellis S., Yancopoulos G.D., et al. Effect of a monoclonal antibody to PCSK9 on LDL cholesterol. N Engl J Med 2012, 366(12):1108-1118.
    • (2012) N Engl J Med , vol.366 , Issue.12 , pp. 1108-1118
    • Stein, E.A.1    Mellis, S.2    Yancopoulos, G.D.3


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