Analysis of a novel erm(T)- and cadDX-carrying plasmid from methicillin-susceptible staphylococcus aureus ST398-t571 of human origin

Journal of Antimicrobial Chemotherapy

Volumn 68, Issue 2, 2013, Pages 471-473

  Gómez sanz, Elena ^a   Kadlec, Kristina ^b   Feßler, Andrea T ^b   Billerbeck, Carmen ^b   Zarazaga, Myriam ^a   Schwarz, Stefan ^b   Torres, Carmen ^a  

^a UNIVERSITY OF LA RIOJA   (Spain)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

Antimicrobial resistance; Horizontal gene transfer; Insertion sequences; Macrolide lincosamide resistance

Indexed keywords

ERYTHROMYCIN;

ADULT; ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CONTROLLED STUDY; ERM GENE; ESCHERICHIA COLI; GENE DOSAGE; GENE INSERTION SEQUENCE; GENETIC ANALYSIS; HUMAN; LETTER; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; RECOMBINANT PLASMID; STAPHYLOCOCCUS SAPROPHYTICUS;

ANTI-BACTERIAL AGENTS; CADMIUM; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ERYTHROMYCIN; GENES, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PLASMIDS; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84872386744     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks411     Document Type: Letter

References (13)

1. Kadlec K, Feßler AT, Hauschild Tet al. Novel and uncommon antimicrobial resistance genes inlivestock-associatedmethicillin-resistant Staphylococcus aureus. Clin Microbiol Infect 2012; 18: 745-55.
2. Kadlec K, Schwarz S. Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Antimicrob Agents Chemother 2010; 54: 915-8.
3. Uhlemann AC, Porcella SF, Trivedi S et al. Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties. mBio 2012; 3: e00027-12.
4. Vandendriessche S, Kadlec K, Schwarz S et al. Methicillin-susceptible Staphylococcus aureus ST398-t571 harbouring the macrolide-lincosamidestreptogramin B resistance gene erm(T) in Belgian hospitals. J Antimicrob Chemother 2011; 66: 2455-9.
5. Gómez-Sanz E, Torres C, Lozano C et al. High diversity of Staphylococcus aureus and Staphylococcus pseudintermedius lineages and toxigenic traits in healthy pet-owning household members. Understanding normal household contact? Comp Immunol Microbiol Infect Dis 2012; in press.
6. Kuroda M, Yamashita A, Hirakawa H et al. Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection. Proc Natl Acad Sci USA 2005; 102: 13272-7.
7. Chen YY, Feng CW, Chiu CF et al. cadDX operon of Streptococcus salivarius 57.I. Appl Environ Microbiol 2008; 74: 1642-5.
8. Crupper SS, Worrell V, Stewart GC et al. Cloning and expression of cadD, a new cadmium resistance gene of Staphylococcus aureus. J Bacteriol 1999; 181: 4071-5.
9. Schwarz S, Feßler AT, Hauschild T et al. Plasmid-mediated resistance to protein biosynthesis inhibitors in staphylococci. Ann N Y Acad Sci 2011; 1241: 82-103.
10. Lozano C, Gómez-Sanz E, Benito D et al. Staphylococcus aureus nasal carriage, virulence traits, antibiotic resistance mechanisms, and genetic lineages in healthy humans in Spain, with detection of CC398 and CC97 strains. Int J Med Microbiol 2011; 301: 500-5.
11. Lozano C, Rezusta A, Gómez P et al. High prevalence of spa types associated with the clonal lineage CC398 among tetracycline-resistant methicillin-resistant Staphylococcus aureus strains in a Spanish hospital. J Antimicrob Chemother 2012; 67: 330-4.
12. Gómez-Sanz E, Torres C, Lozano C et al. Detection, molecular characterization, and clonal diversity of methicillin-resistant Staphylococcus aureus CC398 and CC97 in Spanish slaughter pigs of different age groups. Foodborne Pathog Dis 2010; 7: 1269-77.
13. Price LB, Stegger M, Hasman H et al. Staphylococcus aureus CC398: host adaptation and emergence of methicillin resistance in livestock. mBio 2012; 3: e00305-11.