The impact of the site of blood sampling on pharmacokinetic parameters following sublingual dosing to dogs

Journal of Pharmacological and Toxicological Methods

Volumn 67, Issue 1, 2013, Pages 1-4

  Sohlberg, E ^a   Halldin, M M ^a   Annas, A ^a   Konigsson K ^a   Jansson, B ^a   Pehrson, R ^b   Borg, N ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Absorption; Bioavailability; Jugular vein; Plasma concentrations; Safety margins; Transmucosal

Indexed keywords

COMPOUND A; DRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BLOOD SAMPLING SITE; CENTRIFUGATION; COMPARTMENT MODEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EXPOSURE; DRUG HALF LIFE; FEMALE; JUGULAR VEIN; LEG VEIN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PRECIPITATION; SAPHENOUS VEIN; SINGLE DRUG DOSE;

ANIMALIA; CANIS FAMILIARIS;

EID: 84872380650     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2012.10.004     Document Type: Article

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