Treatments and prescriptions in advanced dementia patients residing in long-term care institutions and at home

Journal of Palliative Medicine

Volumn 16, Issue 1, 2013, Pages 31-37

  Toscani, Franco ^a   Di Giulio, Paola ^a,b   Villani, Daniele ^c   Giunco, Fabrizio ^d   Brunelli, Cinzia ^a   Gentile, Simona ^e   Finetti, Silvia ^a   Charrier, Lorena ^b   Monti, Massimo ^f   Van Der Steen, T ^g  

^a Istituto di Ricerca in Medicina Palliativa   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Neuro rehabilitation and Alzheimer's Disease Evaluation Unit   (Italy)

^d Geriatric Polifunctional Center S Pietro of Monza   (Italy)

^e Ancelle della Carita Hospital   (Italy)

^f Pio Albergo Trivulzio Geriatric Institute   (Italy)

^g VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIDIARRHEAL AGENT; ANTIEMETIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTITHYROID AGENT; ANTIVIRUS AGENT; ANXIOLYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRONCHODILATING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; CORTICOSTEROID; DIURETIC AGENT; EXPECTORANT AGENT; EYE DROPS; GLYCERYL TRINITRATE; HISTAMINE H2 RECEPTOR ANTAGONIST; INSULIN; LAXATIVE; LIDOCAINE; NARCOTIC AGENT; ORAL ANTIDIABETIC AGENT; PRESCRIPTION DRUG; PROTON PUMP INHIBITOR; THYROID HORMONE; UNINDEXED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; DEMENTIA; DIFFUSE LEWY BODY DISEASE; DRUG CLASSIFICATION; FEMALE; FRONTOTEMPORAL DEMENTIA; HOME CARE; HUMAN; INSTITUTIONAL CARE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MIXED DEPRESSION AND DEMENTIA; MULTIINFARCT DEMENTIA; PRESCRIPTION;

AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; ANTIPSYCHOTIC AGENTS; CROSS-SECTIONAL STUDIES; DEMENTIA; DRUG UTILIZATION REVIEW; FEMALE; HOME CARE SERVICES; HUMANS; INAPPROPRIATE PRESCRIBING; ITALY; LOGISTIC MODELS; MALE; NURSING HOMES; PAIN MANAGEMENT; PALLIATIVE CARE; PROSPECTIVE STUDIES; QUALITY OF LIFE;

EID: 84872379337     PISSN: 10966218     EISSN: 15577740     Source Type: Journal    
DOI: 10.1089/jpm.2012.0165     Document Type: Article

References (29)

1. Xie J, Brayne C, Matthews FE, and the Medical Research Council Cognitive Function and Ageing Study collaborators: Survival times in people with dementia: Analysis from population based cohort study with 14 year follow-up. BMJ 2008;336:258-262.
2. van der Steen, JT: Dying with dementia: What we know after more than a decade of research? J Alzheimers Dis 2010;22:37-55.
3. Gill TM, Gahbauer EA, Han L, et al.: Trajectories of disability in the last year of life. N Engl J Med 2010;362:1173-1180.
4. Davies E, Higginson IJ (eds): Better palliative care for older people. WHO Regional Office for Europe. 2004. www.euro .who.int/document/E82933.pdf. (Last accessed June 2009.)
5. Lau DT, Kasper JD, Potter DEB, et al.: Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly Nursing Home residents. Arch Intern Med 2005;165:68-74.
6. Holmes HM, Hayley DC, Alexander GC, et al.: Reconsidering medication appropriateness for patients late in life. Arch Intern Med 2006;166:605-609.
7. Mitchell SL, Teno JM, Miller SC, et al.: A national study of the location of death for older persons with dementia. J Am Geriatr Soc 2005;53:299-305.
8. Fialová D, Topinková E, Gambassi G, et al.: Potentially inappropriate medications among elderly home care patients in Europe. JAMA 2005;293:1348-1358.
9. Blass DM, Black BS, Phillips H, et al.: Medication use in nursing home residents with advanced dementia. Int J Geriatr Psychiatry 2008;23:490-496.
10. Directory of the Regione Lombardia RSAs. www.famiglia .regione.lombardia.it/shared/ccurl/111/206/elenco + RSA + 20.03.09.xls. (Last accessed March 2011.)
11. Directory of the Regione Emilia-Romagna RSAs. www .emiliaromagnasociale. it/emiliaromagnasociale/sips/ricerca-go.asp. (Last accessed March 2011.)
12. Sclan SG, Reisberg B: Functional assessment staging (FAST) in Alzheimer's disease: Reliability, validity, and ordinality. Int Psychogeriatr 1992;4:55-69.
13. WHO Collaborating Centre for Drug Statistics Methodology, Guidelines for ATC Classification and DDD Assignment 2010. www.whocc.no/atc-ddd-index. (Last accessed December 2009.)
14. National Pressure Ulcer Advisory Panel (NPUAP) Staging System. www.npuap.org/pr2.htm. (Last accessed December 2010.)
15. Holmes HM, Sachs GA, Shega JW, et al.: Integrating palliative medicine into the care of persons with advanced dementia: Identifying appropriate medications use. J Am Geriatr Soc 2008;56:1306-1311.
16. Johnell K, Fastbom J: Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700,000 elderly. Scand J Prim Health Care 2008;26:86-91.
17. Tjia J, Rothman MR, Kiely DK, et al.: Daily medication use in nursing home residents with advanced dementia. J Am Geriatr Soc 2010;58:880-888.
18. Elseviers MM, Vancer Stichele RR, Van Bortel L: Drug utilization in Belgian Nursing Homes: Impact of residents' and institutional characteristics. Pharmacoepidemiol Drug Saf 2010;19:1041-1048.
19. Zwakhalen SM, Koopmans RT, Geels PJ, et al.: The prevalence of pain in nursing home residents with dementia measured using an observational pain scale. Eur J Pain 2009;13:89-93.
20. Williams CS, Zimmerman S, Sloane PD, et al.: Characteristics associated with pain in long-term care residents with dementia. Gerontologist 2005;45:68-73.
21. Toscani F, Di Giulio P, Brunelli C, et al.: End-of-Life Observatory Group. How people die in hospital general wards: A descriptive study. J Pain Symptom Manage 2005;30:33-40.
22. Lopez RP, Amella EJ, Strumpf NE, et al.: The influence of nursing home culture on the use of feeding tubes. Arch Intern Med 2010;170:83-88.
23. Luchetti M: Eluana Englaro, chronicle of a death foretold: Ethical considerations on the recent right-to-die case in Italy. J Med Ethics 2010;36:333-335.
24. Sacred Congregation for the Doctrine of the Faith. Declaration on Euthanasia "Jura et Bona," May 5, 1980. www.rc.net/manila/safe/7- Gospel%20of%20Life/CDF-Declaration%20on%20Euthanasia.doc. (Last accessed September 2010.)
25. Meyer G, Kopke S, Haastert B, et al.: Restraint use among nursing home residents: Cross sectional study and prospective cohort study. J Clin Nurs 2009;18:981-990.
26. Rochon PA, Normand S, Gomes T, et al.: Antipsychotic therapy and short-term serious events in older adults with dementia. Arch Intern Med 2008;168:1090-1096.
27. Mitchell SL, Teno JM, Kiely DK, et al.: The clinical course of advanced dementia. N Engl J Med 2009;361:1529-1538.
28. UK Department of Health. End of Life Care Strategy: Promoting High Quality Care for All Adults at the End of Life. 2008. www.dh.gov.uk/prod-consum- dh/groups/dh-digitalassets/@dh/@en/documents/digitalasset/dh-086345.pdf. (Last accessed March 2010.)
29. Glare P, Virik K, Jones M, et al.: A systematic review of physicians' survival predictions in terminally ill cancer patients. BMJ 2003;327:195-198.