Coupling to the surface of liposomes alters the immunogenicity of hepatitis C virus-derived peptides and confers sterile immunity

Biochemical and Biophysical Research Communications

Volumn 430, Issue 1, 2013, Pages 183-189

  Takagi, Akira ^a   Kobayashi, Nobuharu ^a   Taneichi, Maiko ^b   Uchida, Tetsuya ^b   Akatsuka, Toshitaka ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

CTL; Hepatitis C virus; Immunogenicity; Liposome; Peptides; Vaccine

Indexed keywords

FREUND ADJUVANT; GAMMA INTERFERON; HEPATITIS B VIRUS CORE 128-140; HEPATITIS C VACCINE; HLA A ANTIGEN; LIP 603; LIPOSOME; P 603; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG EFFICACY; EMULSION; ENZYME LINKED IMMUNOSPOT ASSAY; HEPATITIS C; HEPATITIS C VIRUS; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; LIPOSOMAL DELIVERY; LONG TERM MEMORY; LYMPHOMA CELL LINE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; SURFACE PROPERTY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD4; EPITOPES, T-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C ANTIGENS; HLA-A2 ANTIGEN; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; LIPOSOMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDE FRAGMENTS; T-LYMPHOCYTES, CYTOTOXIC; VIRAL HEPATITIS VACCINES;

HEPATITIS C VIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS; VACCINIA VIRUS;

EID: 84872371056     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.028     Document Type: Article

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