Sodium citrate 4% versus heparin as a lock solution in hemodialysis patients with central venous catheters

American Journal of Health-System Pharmacy

Volumn 70, Issue 2, 2013, Pages 131-136

  Yon, Calantha K ^a,b   Low, Chai L ^b,c  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VASD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SODIUM; HEPARIN;

ADULT; AGED; ARTICLE; BLEEDING; BLOOD CLOTTING; CATHETER INFECTION; CATHETER THROMBOSIS; CENTRAL VENOUS CATHETER; DRUG EFFECT; FEMALE; HEMODIALYSIS PATIENT; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

EID: 84872360669     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp120300     Document Type: Article

References (13)

1. National Kidney Foundation. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for 2006 Updates: hemodialysis adequacy, peritoneal dialysis adequacy and vascular access. Am J Kidney Disease. 2006; 48(suppl 1): S1-322.
2. Rayner HC, Besarab A, Brown WW et al. Vascular access results from the Dialysis Outcomes and Practice Patterns Study (DOPPS): performance against Kidney Disease Outcomes Quality Initiative (K/DOQI) Clinical Practice Guidelines. Am J Kidney Dis. 2004; 44(suppl 3):22-6.
3. U.S. Renal Data System. USRDS 2009 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. www.usrds.org/atlas09.aspx (accessed 2012 Aug 30).
4. Weijmer MC, van den Dorpel MA, Van de Ven PJ et al. Randomized, clinical trial comparison of trisodium citrate 30% and heparin as catheter-locking solution in hemodialysis patients. J Am Soc Nephrol. 2005; 16:2769-77.
5. Agharazii M, Plamondon I, Lebel M et al. Estimation of heparin leak into the systemic circulation after central venous catheter heparin lock. Nephrol Dial Transplant. 2005; 20:1238-40. (Pubitemid 40862117)
6. Karaaslan H, Peyronnet P, Benevent D et al. Risk of heparin lock-related bleeding when using indwelling venous catheter in hemodialysis. Nephrol Dial Transplant. 2001; 16:2072-4. (Pubitemid 32970572)
7. Ash SR, Mankus RA, Sutton JM et al. Concentrated sodium citrate (23%) for catheter lock. Hemodial Int. 2000; 4:22-31.
8. Grudzinski L, Quinan P, Kwok S et al. Sodium citrate 4% locking solution for central venous dialysis catheters - an effective, more cost-effective alternative to heparin. Nephrol Dial Transplant. 2007; 22:471-6. (Pubitemid 46189891)
9. Lok CE, Appleton D, Bhola C et al. Trisodium citrate 4% - an alternative to heparin capping of hemodialysis catheters. Nephrol Dial Transplant. 2007; 22:477-83. (Pubitemid 46189892)
10. Shanks RM, Sargent JL, Martinez RM et al. Catheter lock solutions influence staphylococcal biofilm formation on abiotic surfaces. Nephrol Dial Transplant. 2006; 21:2247-55. (Pubitemid 44295052)
11. Weijmer MC, Debetss-Ossenkopp YJ, Van de Vondervoort FJ et al. Superior antimicrobial activity of trisodium citrate over heparin for catheter locking. Nephrol Dial Transplant. 2002; 17:2189-95. (Pubitemid 35446677)
12. FDA issues warning on triCitrasol dialysis catheter anticoagulant. FDA talk paper T00-16. Rockville, MD: Food and Drug Administration; 2000.
13. Power A, Duncan N, Singh SK et al. Sodium citrate versus heparin catheter locks for cuffed central venous catheters: a single-center randomized controlled trial. Am J Kidney Dis. 2009; 53:1034-41.