메뉴 건너뛰기




Volumn 4, Issue 1, 2013, Pages 36-49

Progesterone-Inducible Cytokeratin 5-Positive Cells in Luminal Breast Cancer Exhibit Progenitor Properties

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 5; ESTROGEN RECEPTOR; GESTAGEN; GREEN FLUORESCENT PROTEIN; LUCIFERASE; MESSENGER RNA; PROGESTERONE; PROGESTERONE RECEPTOR; STEROID HORMONE; VIRUS VECTOR;

EID: 84872348736     PISSN: 18688497     EISSN: 18688500     Source Type: Journal    
DOI: 10.1007/s12672-012-0127-5     Document Type: Article
Times cited : (40)

References (63)
  • 1
    • 79951931750 scopus 로고    scopus 로고
    • Breast cancer risk in relation to the interval between menopause and starting hormone therapy
    • Beral V, Reeves G, Bull D, Green J (2011) Breast cancer risk in relation to the interval between menopause and starting hormone therapy. J Natl Cancer Inst 103(4): 296-305.
    • (2011) J Natl Cancer Inst , vol.103 , Issue.4 , pp. 296-305
    • Beral, V.1    Reeves, G.2    Bull, D.3    Green, J.4
  • 2
    • 77958138780 scopus 로고    scopus 로고
    • Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women
    • Chlebowski RT, Anderson GL, Gass M, Lane DS, Aragaki AK, Kuller LH et al (2010) Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA 304(15): 1684-1692.
    • (2010) Jama , vol.304 , Issue.15 , pp. 1684-1692
    • Chlebowski, R.T.1    Anderson, G.L.2    Gass, M.3    Lane, D.S.4    Aragaki, A.K.5    Kuller, L.H.6
  • 3
    • 51649125766 scopus 로고    scopus 로고
    • Progestins in hormone replacement therapies reactivate cancer stem cells in women with preexisting breast cancers: a hypothesis
    • Horwitz KB, Sartorius CA (2008) Progestins in hormone replacement therapies reactivate cancer stem cells in women with preexisting breast cancers: a hypothesis. J Clin Endocrinol Metab 93(9): 3295-3298.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.9 , pp. 3295-3298
    • Horwitz, K.B.1    Sartorius, C.A.2
  • 4
    • 84860331033 scopus 로고    scopus 로고
    • Progesterone regulation of stem and progenitor cells in normal and malignant breast
    • Axlund SD, Sartorius CA (2012) Progesterone regulation of stem and progenitor cells in normal and malignant breast. Mol Cell Endocrinol 357(1-2): 71-79.
    • (2012) Mol Cell Endocrinol , vol.357 , Issue.1-2 , pp. 71-79
    • Axlund, S.D.1    Sartorius, C.A.2
  • 5
    • 27544472561 scopus 로고
    • Extinction of experimental mammary cancer. I. Estradiol-17beta and progesterone
    • Huggins C, Moon RC, Morii S (1962) Extinction of experimental mammary cancer. I. Estradiol-17beta and progesterone. Proc Natl Acad Sci U S A 48: 379-386.
    • (1962) Proc Natl Acad Sci U S A , vol.48 , pp. 379-386
    • Huggins, C.1    Moon, R.C.2    Morii, S.3
  • 6
    • 0029791362 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate accelerates the development and increases the incidence of mouse mammary tumors induced by dimethylbenzanthracene
    • Aldaz CM, Liao QY, LaBate M, Johnston DA (1996) Medroxyprogesterone acetate accelerates the development and increases the incidence of mouse mammary tumors induced by dimethylbenzanthracene. Carcinogenesis 17(9): 2069-2072.
    • (1996) Carcinogenesis , vol.17 , Issue.9 , pp. 2069-2072
    • Aldaz, C.M.1    Liao, Q.Y.2    LaBate, M.3    Johnston, D.A.4
  • 7
    • 0033199889 scopus 로고    scopus 로고
    • Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function
    • Lydon JP, Ge G, Kittrell FS, Medina D, O'Malley BW (1999) Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res 59(17): 4276-4284.
    • (1999) Cancer Res , vol.59 , Issue.17 , pp. 4276-4284
    • Lydon, J.P.1    Ge, G.2    Kittrell, F.S.3    Medina, D.4    O'Malley, B.W.5
  • 10
    • 67649669246 scopus 로고    scopus 로고
    • DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast
    • Graham JD, Mote PA, Salagame U, van Dijk JH, Balleine RL, Huschtscha LI et al (2009) DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast. Endocrinology 150(7): 3318-3326.
    • (2009) Endocrinology , vol.150 , Issue.7 , pp. 3318-3326
    • Graham, J.D.1    Mote, P.A.2    Salagame, U.3    van Dijk, J.H.4    Balleine, R.L.5    Huschtscha, L.I.6
  • 11
    • 44449142900 scopus 로고    scopus 로고
    • Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts
    • Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA (2008) Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A 105(15): 5774-5779.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.15 , pp. 5774-5779
    • Horwitz, K.B.1    Dye, W.W.2    Harrell, J.C.3    Kabos, P.4    Sartorius, C.A.5
  • 12
    • 78149284767 scopus 로고    scopus 로고
    • RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
    • Gonzalez-Suarez E, Jacob AP, Jones J, Miller R, Roudier-Meyer MP, Erwert R et al (2010) RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature 468(7320): 103-107.
    • (2010) Nature , vol.468 , Issue.7320 , pp. 103-107
    • Gonzalez-Suarez, E.1    Jacob, A.P.2    Jones, J.3    Miller, R.4    Roudier-Meyer, M.P.5    Erwert, R.6
  • 13
    • 78149284013 scopus 로고    scopus 로고
    • Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
    • Schramek D, Leibbrandt A, Sigl V, Kenner L, Pospisilik JA, Lee HJ et al (2010) Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 468(7320): 98-102.
    • (2010) Nature , vol.468 , Issue.7320 , pp. 98-102
    • Schramek, D.1    Leibbrandt, A.2    Sigl, V.3    Kenner, L.4    Pospisilik, J.A.5    Lee, H.J.6
  • 14
    • 84860328986 scopus 로고    scopus 로고
    • The biology of progesterone receptor in the normal mammary gland and in breast cancer
    • Obr AE, Edwards DP (2012) The biology of progesterone receptor in the normal mammary gland and in breast cancer. Mol Cell Endocrinol 357(1-2): 4-17.
    • (2012) Mol Cell Endocrinol , vol.357 , Issue.1-2 , pp. 4-17
    • Obr, A.E.1    Edwards, D.P.2
  • 15
    • 79959213451 scopus 로고    scopus 로고
    • Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers
    • Kabos P, Haughian JM, Wang X, Dye WW, Finlayson C, Elias A et al (2011) Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers. Breast Cancer Res Treat 128(1): 45-55.
    • (2011) Breast Cancer Res Treat , vol.128 , Issue.1 , pp. 45-55
    • Kabos, P.1    Haughian, J.M.2    Wang, X.3    Dye, W.W.4    Finlayson, C.5    Elias, A.6
  • 16
    • 84878017599 scopus 로고    scopus 로고
    • Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4
    • doi:10.1038/onc.2012.275
    • Cittelly DM, Finlay-Schultz J, Howe EN, Spoelstra NS, Axlund SD, Hendricks P, et al (2012) Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. Oncogene. doi: 10. 1038/onc. 2012. 275.
    • (2012) Oncogene
    • Cittelly, D.M.1    Finlay-Schultz, J.2    Howe, E.N.3    Spoelstra, N.S.4    Axlund, S.D.5    Hendricks, P.6
  • 17
    • 58849100464 scopus 로고    scopus 로고
    • Do 'basal-like' breast cancers really exist?
    • Gusterson B (2009) Do 'basal-like' breast cancers really exist? Nat Rev Cancer 9(2): 128-134.
    • (2009) Nat Rev Cancer , vol.9 , Issue.2 , pp. 128-134
    • Gusterson, B.1
  • 18
    • 21044455192 scopus 로고    scopus 로고
    • Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer
    • Gusterson BA, Ross DT, Heath VJ, Stein T (2005) Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer. Breast Cancer Res 7(4): 143-148.
    • (2005) Breast Cancer Res , vol.7 , Issue.4 , pp. 143-148
    • Gusterson, B.A.1    Ross, D.T.2    Heath, V.J.3    Stein, T.4
  • 19
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH et al (2009) Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 15(8): 907-913.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3    Forrest, N.C.4    Pal, B.5    Hart, A.H.6
  • 20
    • 0036278690 scopus 로고    scopus 로고
    • Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept
    • Boecker W, Moll R, Poremba C, Holland R, van Diest PJ, Dervan P et al (2002) Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept. Lab Invest 82(6): 737-746.
    • (2002) Lab Invest , vol.82 , Issue.6 , pp. 737-746
    • Boecker, W.1    Moll, R.2    Poremba, C.3    Holland, R.4    van Diest, P.J.5    Dervan, P.6
  • 25
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 Is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M et al (2007) ALDH1 Is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1(5): 555-567.
    • (2007) Cell Stem Cell , vol.1 , Issue.5 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3    Monville, F.4    Dutcher, J.5    Brown, M.6
  • 26
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P et al (2009) Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 69(4): 1302-1313.
    • (2009) Cancer Res , vol.69 , Issue.4 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3    Wicinski, J.4    Cervera, N.5    Finetti, P.6
  • 28
    • 33846581488 scopus 로고    scopus 로고
    • The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle
    • Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP (2007) The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol 21(2): 359-375.
    • (2007) Mol Endocrinol , vol.21 , Issue.2 , pp. 359-375
    • Boonyaratanakornkit, V.1    McGowan, E.2    Sherman, L.3    Mancini, M.A.4    Cheskis, B.J.5    Edwards, D.P.6
  • 29
    • 0029844145 scopus 로고    scopus 로고
    • Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation
    • Pink JJ, Bilimoria MM, Assikis J, Jordan VC (1996) Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation. Br J Cancer 74(8): 1227-1236.
    • (1996) Br J Cancer , vol.74 , Issue.8 , pp. 1227-1236
    • Pink, J.J.1    Bilimoria, M.M.2    Assikis, J.3    Jordan, V.C.4
  • 30
    • 0027269672 scopus 로고
    • Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice
    • Byrne C, Fuchs E (1993) Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice. Mol Cell Biol 13(6): 3176-3190.
    • (1993) Mol Cell Biol , vol.13 , Issue.6 , pp. 3176-3190
    • Byrne, C.1    Fuchs, E.2
  • 31
    • 0033304672 scopus 로고    scopus 로고
    • Cloning of the mouse somatostatin receptor subtype 5 gene: promoter structure and function
    • Gordon DF, Woodmansee WW, Lewis SR, James RA, Wood WM, Ridgway EC (1999) Cloning of the mouse somatostatin receptor subtype 5 gene: promoter structure and function. Endocrinology 140(12): 5598-5608.
    • (1999) Endocrinology , vol.140 , Issue.12 , pp. 5598-5608
    • Gordon, D.F.1    Woodmansee, W.W.2    Lewis, S.R.3    James, R.A.4    Wood, W.M.5    Ridgway, E.C.6
  • 32
    • 84866427443 scopus 로고    scopus 로고
    • A High-Content Assay to Identify Small-Molecule Modulators of a Cancer Stem Cell Population in Luminal Breast Cancer
    • Yoo BH, Axlund SD, Kabos P, Reid BG, Schaack J, Sartorius CA, et al (2012) A High-Content Assay to Identify Small-Molecule Modulators of a Cancer Stem Cell Population in Luminal Breast Cancer. J Biomol Screen 17(9): 1211-1220.
    • (2012) J Biomol Screen , vol.17 , Issue.9 , pp. 1211-1220
    • Yoo, B.H.1    Axlund, S.D.2    Kabos, P.3    Reid, B.G.4    Schaack, J.5    Sartorius, C.A.6
  • 33
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3(6): 1101-1108.
    • (2008) Nat Protoc , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 35
    • 0035726623 scopus 로고    scopus 로고
    • Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294
    • Shen T, Horwitz KB, Lange CA (2001) Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. Mol Cell Biol 21(18): 6122-6131.
    • (2001) Mol Cell Biol , vol.21 , Issue.18 , pp. 6122-6131
    • Shen, T.1    Horwitz, K.B.2    Lange, C.A.3
  • 36
    • 0017686818 scopus 로고
    • Binding of methyltrienolone (R1881) to a progesterone receptor-like component of human prostatic cytosol
    • Cowan RA, Cowan SK, Grant JK (1977) Binding of methyltrienolone (R1881) to a progesterone receptor-like component of human prostatic cytosol. J Endocrinol 74(2): 281-289.
    • (1977) J Endocrinol , vol.74 , Issue.2 , pp. 281-289
    • Cowan, R.A.1    Cowan, S.K.2    Grant, J.K.3
  • 37
    • 0024309127 scopus 로고
    • A quantitative comparison of dual control of a hormone response element by progestins and glucocorticoids in the same cell line
    • Nordeen SK, Kuhnel B, Lawler-Heavner J, Barber DA, Edwards DP (1989) A quantitative comparison of dual control of a hormone response element by progestins and glucocorticoids in the same cell line. Mol Endocrinol 3(8): 1270-1278.
    • (1989) Mol Endocrinol , vol.3 , Issue.8 , pp. 1270-1278
    • Nordeen, S.K.1    Kuhnel, B.2    Lawler-Heavner, J.3    Barber, D.A.4    Edwards, D.P.5
  • 38
    • 36748998921 scopus 로고    scopus 로고
    • Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen
    • Ariazi EA, Leitao A, Oprea TI, Chen B, Louis T, Bertucci AM et al (2007) Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen. Mol Cancer Ther 6(11): 2817-2827.
    • (2007) Mol Cancer Ther , vol.6 , Issue.11 , pp. 2817-2827
    • Ariazi, E.A.1    Leitao, A.2    Oprea, T.I.3    Chen, B.4    Louis, T.5    Bertucci, A.M.6
  • 39
    • 0037570621 scopus 로고    scopus 로고
    • Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification
    • Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW (2003) Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol 23(11): 3763-3773.
    • (2003) Mol Cell Biol , vol.23 , Issue.11 , pp. 3763-3773
    • Li, X.1    Wong, J.2    Tsai, S.Y.3    Tsai, M.J.4    O'Malley, B.W.5
  • 40
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H (2011) The cancer stem cell: premises, promises and challenges. Nat Med 17(3): 313-319.
    • (2011) Nat Med , vol.17 , Issue.3 , pp. 313-319
    • Clevers, H.1
  • 41
    • 0026051580 scopus 로고
    • Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes
    • Musgrove EA, Lee CS, Sutherland RL (1991) Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes. Mol Cell Biol 11(10): 5032-5043.
    • (1991) Mol Cell Biol , vol.11 , Issue.10 , pp. 5032-5043
    • Musgrove, E.A.1    Lee, C.S.2    Sutherland, R.L.3
  • 42
    • 77954860302 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer
    • Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani SA et al (2010) Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia 15(2): 235-252.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 235-252
    • Blick, T.1    Hugo, H.2    Widodo, E.3    Waltham, M.4    Pinto, C.5    Mani, S.A.6
  • 43
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ et al (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17(10): 1253-1270.
    • (2003) Genes Dev , vol.17 , Issue.10 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6
  • 44
    • 40949121882 scopus 로고    scopus 로고
    • Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
    • Cheang MC, Voduc D, Bajdik C, Leung S, McKinney S, Chia SK et al (2008) Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res 14(5): 1368-1376.
    • (2008) Clin Cancer Res , vol.14 , Issue.5 , pp. 1368-1376
    • Cheang, M.C.1    Voduc, D.2    Bajdik, C.3    Leung, S.4    McKinney, S.5    Chia, S.K.6
  • 45
    • 0348134978 scopus 로고    scopus 로고
    • Evidence of progenitor cells of glandular and myoepithelial cell lineages in the human adult female breast epithelium: a new progenitor (adult stem) cell concept
    • Boecker W, Buerger H (2003) Evidence of progenitor cells of glandular and myoepithelial cell lineages in the human adult female breast epithelium: a new progenitor (adult stem) cell concept. Cell Prolif 36(Suppl 1): 73-84.
    • (2003) Cell Prolif , vol.36 , Issue.SUPPL. 1 , pp. 73-84
    • Boecker, W.1    Buerger, H.2
  • 46
    • 0036928732 scopus 로고    scopus 로고
    • Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells
    • Tran CP, Lin C, Yamashiro J, Reiter RE (2002) Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells. Mol Cancer Res 1(2): 113-121.
    • (2002) Mol Cancer Res , vol.1 , Issue.2 , pp. 113-121
    • Tran, C.P.1    Lin, C.2    Yamashiro, J.3    Reiter, R.E.4
  • 47
    • 3242743136 scopus 로고    scopus 로고
    • In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue
    • Uzgare AR, Xu Y, Isaacs JT (2004) In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue. J Cell Biochem 91(1): 196-205.
    • (2004) J Cell Biochem , vol.91 , Issue.1 , pp. 196-205
    • Uzgare, A.R.1    Xu, Y.2    Isaacs, J.T.3
  • 50
    • 79952121979 scopus 로고    scopus 로고
    • Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
    • Iliopoulos D, Hirsch HA, Wang G, Struhl K (2011) Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci U S A 108(4): 1397-1402.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.4 , pp. 1397-1402
    • Iliopoulos, D.1    Hirsch, H.A.2    Wang, G.3    Struhl, K.4
  • 54
    • 0026079509 scopus 로고
    • Direct transcriptional regulation of the progesterone receptor by retinoic acid diminishes progestin responsiveness in the breast cancer cell line T-47D
    • Clarke CL, Graham J, Roman SD, Sutherland RL (1991) Direct transcriptional regulation of the progesterone receptor by retinoic acid diminishes progestin responsiveness in the breast cancer cell line T-47D. J Biol Chem 266(28): 18969-18975.
    • (1991) J Biol Chem , vol.266 , Issue.28 , pp. 18969-18975
    • Clarke, C.L.1    Graham, J.2    Roman, S.D.3    Sutherland, R.L.4
  • 55
    • 0026762673 scopus 로고
    • Expression and regulation of retinoic acid receptors in human breast cancer cells
    • Roman SD, Clarke CL, Hall RE, Alexander IE, Sutherland RL (1992) Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res 52(8): 2236-2242.
    • (1992) Cancer Res , vol.52 , Issue.8 , pp. 2236-2242
    • Roman, S.D.1    Clarke, C.L.2    Hall, R.E.3    Alexander, I.E.4    Sutherland, R.L.5
  • 56
    • 78649646015 scopus 로고    scopus 로고
    • Retinoids regulate stem cell differentiation
    • Gudas LJ, Wagner JA (2011) Retinoids regulate stem cell differentiation. J Cell Physiol 226(2): 322-330.
    • (2011) J Cell Physiol , vol.226 , Issue.2 , pp. 322-330
    • Gudas, L.J.1    Wagner, J.A.2
  • 57
    • 0037221180 scopus 로고    scopus 로고
    • All-trans retinoic acid induces differentiation of ducts and endocrine cells by mesenchymal/epithelial interactions in embryonic pancreas
    • Tulachan SS, Doi R, Kawaguchi Y, Tsuji S, Nakajima S, Masui T et al (2003) All-trans retinoic acid induces differentiation of ducts and endocrine cells by mesenchymal/epithelial interactions in embryonic pancreas. Diabetes 52(1): 76-84.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 76-84
    • Tulachan, S.S.1    Doi, R.2    Kawaguchi, Y.3    Tsuji, S.4    Nakajima, S.5    Masui, T.6
  • 58
    • 0033764652 scopus 로고    scopus 로고
    • Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27
    • Baldassarre G, Boccia A, Bruni P, Sandomenico C, Barone MV, Pepe S et al (2000) Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. Cell Growth Differ 11(10): 517-526.
    • (2000) Cell Growth Differ , vol.11 , Issue.10 , pp. 517-526
    • Baldassarre, G.1    Boccia, A.2    Bruni, P.3    Sandomenico, C.4    Barone, M.V.5    Pepe, S.6
  • 59
    • 78649668597 scopus 로고    scopus 로고
    • Retinoids, retinoic acid receptors, and cancer
    • Tang XH, Gudas LJ (2011) Retinoids, retinoic acid receptors, and cancer. Annu Rev Pathol 6: 345-364.
    • (2011) Annu Rev Pathol , vol.6 , pp. 345-364
    • Tang, X.H.1    Gudas, L.J.2
  • 60
    • 78649682080 scopus 로고    scopus 로고
    • Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations
    • Koay DC, Zerillo C, Narayan M, Harris LN, DiGiovanna MP (2010) Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations. Breast Cancer Res 12(4): R62.
    • (2010) Breast Cancer Res , vol.12 , Issue.4
    • Koay, D.C.1    Zerillo, C.2    Narayan, M.3    Harris, L.N.4    DiGiovanna, M.P.5
  • 62
    • 84866557855 scopus 로고    scopus 로고
    • Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen dependent gene signatures
    • Kabos P, Finlay-Schultz J, Li C, Kline E, Finlayson C, Wisell J, et al (2012) Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen dependent gene signatures. Breast Cancer Res Treat 135(2): 415-432.
    • (2012) Breast Cancer Res Treat , vol.135 , Issue.2 , pp. 415-432
    • Kabos, P.1    Finlay-Schultz, J.2    Li, C.3    Kline, E.4    Finlayson, C.5    Wisell, J.6
  • 63
    • 84863602985 scopus 로고    scopus 로고
    • Modeling of the growth kinetics of occult breast tumors: role in interpretation of studies of prevention and menopausal hormone therapy
    • Santen RJ, Yue W, Heitjan DF (2012) Modeling of the growth kinetics of occult breast tumors: role in interpretation of studies of prevention and menopausal hormone therapy. Cancer Epidemiol Biomark Prev 21(7): 1038-1048.
    • (2012) Cancer Epidemiol Biomark Prev , vol.21 , Issue.7 , pp. 1038-1048
    • Santen, R.J.1    Yue, W.2    Heitjan, D.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.