Association of interleukin-1 gene polymorphisms with multiple sclerosis: A meta-analysis

Inflammation Research

Volumn 62, Issue 1, 2013, Pages 97-106

  Huang, Jian ^a   Xie, Zi Kang ^a   Lu, Rong Bin ^a   Xie, Zheng Fu ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Interleukin 1; Meta analysis; Multiple sclerosis; Polymorphism

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC RISK; HIGH RISK PATIENT; HOMOZYGOSITY; HUMAN; IMMUNOPATHOGENESIS; INTERLEUKIN 1 GENE; MAJOR CLINICAL STUDY; MULTIPLE SCLEROSIS; ONSET AGE; VARIABLE NUMBER OF TANDEM REPEAT;

HUMANS; INTERLEUKIN-1; MINISATELLITE REPEATS; MULTIPLE SCLEROSIS; POLYMORPHISM, GENETIC;

EID: 84872331843     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-012-0556-1     Document Type: Article

References (32)

1. Matsuda M, Tsukada N, Miyagi K, Yanagisawa N. Increased interleukin-1 production by peripheral blood mononuclear cells in patients with multiple sclerosis. J Neurol Sci. 1991;102:100-4.
2. Imamura K, Suzumura A, Hayashi F, Marunouchi T. Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients. Acta Neurol Scand. 1993;87:281-5.
3. Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol. 1995;37:424-35.
4. Lamkanfi M, Walle LV, Kanneganti TD. Deregulated inflammasome signaling in disease. Immunol Rev. 2011;243:163-73.
5. Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009;27:519-50.
6. Badovinac V, Mostarica-Stojković M, Dinarello CA, Stosić- Grujicić S. Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells. J Neuroimmunol. 1998;85:87-95.
7. Burger D, Molnarfi N, Weber MS, Brandt KJ, Benkhoucha M, Gruaz L, et al. Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis. Proc Natl Acad Sci USA. 2009;106:4355-9.
8. Erbek SS, Yurtcu E, Erbek S, Atac FB, Sahin FI, Cakmak O. Proinflammatory cytokine single nucleotide polymorphisms in nasal polyposis. Arch Otolaryngol Head Neck Surg. 2007;133:705-9.
9. Garcia-González MA, Aisa MA, Strunk M, Benito R, Piazuelo E, Jiménez P, et al. Relevance of IL-1 and TNF gene polymorphisms on interleukin-1beta and tumor necrosis factor-alpha gastric mucosal production. Hum Immunol. 2009;70:935-45.
10. Tarlow JK, Blakemore AI, Lennard A, Solari R, Hughes HN, Steinkasserer A, et al. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Hum Genet. 1993;91:403-4.
11. Crusius JB, Pena AS, Van Oosten BW, Bioque G, Garcia A, Dijkstra CD, et al. Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis. Lancet. 1995;346:979.
12. Huang WX, He B, Hillert J. An interleukin 1-receptor-antagonist gene polymorphism is not associated with multiple sclerosis. J Neuroimmunol. 1996;67:143-4.
13. de la Concha EG, Arroyo R, Crusius JB, Campillo JA, Martin C, Varela de Seijas E, et al. Combined effect of HLA-DRB1*1501 and interleukin-1 receptor antagonist gene allele 2 in susceptibility to relapsing/remitting multiple sclerosis. J Neuroimmunol. 1997;80:172-8.
14. Schrijver HM, Crusius JB, Uitdehaag BM, Garcia González MA, Kostense PJ, Polman CH, et al. Association of interleukin-1beta and interleukin-1 receptor antagonist genes with disease severity in MS. Neurology. 1999;52:595-9.
15. Sciacca FL, Ferri C, Vandenbroeck K, Veglia F, Gobbi C, Martinelli F, et al. Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients. Neurology. 1999;52:1896-8.
16. Kantarci OH, Atkinson EJ, Hebrink DD, McMurray CT, Weinshenker BG. Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis. J Neuroimmunol. 2000;106:220-7.
17. Ferri C, Sciacca FL, Grimaldi LE, Veglia F, Magnani G, Santuccio G, et al. Lack of association between IL-1A and IL-1B promoter polymorphisms and multiple sclerosis. J Neurol Neurosurg Psychiatry. 2000;69:564-5.
18. Luomala M, Lehtima?ki T, Elovaara I, Wang X, Ukkonen M, Mattila K, et al. A study of interleukin-1 cluster genes in susceptibility to and severity of multiple sclerosis. J Neurol Sci. 2001;185:123-7.
19. Niino M, Kikuchi S, Fukazawa T, Yabe I, Sasaki H, Tashiro K. Genetic polymorphisms of IL-1beta and IL-1 receptor antagonist in association with multiple sclerosis in Japanese patients. J Neuroimmunol. 2001;118:295-9.
20. Mann CL, Davies MB, Stevenson VL, Leary SM, Boggild MD, Ko Ko C, et al. Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity. J Neuroimmunol. 2002;129:197-204.
21. Hooper-van Veen T, Schrijver HM, Zwiers A, Crusius JB, Knol DL, Kalkers NF, et al. The interleukin-1 gene family in multiple sclerosis susceptibility and disease course. Mult Scler. 2003;9:535-9.
22. Dincić E, Zivković M, Stanković A, Obradović D, Alavantić D, Kostić V, et al. Association of polymorphisms in CTLA-4, IL-1ra and IL-1beta genes with multiple sclerosis in Serbian population. J Neuroimmunol. 2006;177:146-50.
23. Sarial S, Shokrgozar MA, Amirzargar A, Shokri F, Radfar J, Zohrevand P, et al. IL-1, IL-1R and TNFalpha gene polymorphisms in Iranian patients with multiple sclerosis. Iran J Allergy Asthma Immunol. 2008;7:37-40.
24. Aggelakis K, Zacharaki F, Dardiotis E, Xiromerisiou G, Tsimourtou V, Ralli S, et al. Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms in Greek multiple sclerosis (MS) patients with bout-onset MS. Neurol Sci. 2010;31:253-7.
25. Borzani I, Tola MR, Caniatti L, Collins A, De Santis G, Luiselli D, et al. The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population. Eur J Neurol. 2010;17:930-8.
26. Mirowska-Guzel D, Gromadzka G, Mach A, Czlonkowski A, Czlonkowska A. Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF a polymorphisms with risk and clinical course of multiple sclerosis in a Polish population. J Neuroimmunol. 2011;236:87-92.
27. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983;13:227-31.
28. McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001;50:121-7.
29. Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the ''McDonald Criteria''. Ann Neurol. 2005; 58:840-6.
30. Nikolopoulos GK, Masgala A, Tsiara C, Limitsiou OK, Karnaouri AC, Dimou NL, et al. Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controls. Eur J Neurol. 2011;18:944-51.
31. Han B, Eskin E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am J Hum Genet. 2011;88:586-98.
32. Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes. Eur J Immunol. 1998;28:2598-602.