메뉴 건너뛰기




Volumn 131, Issue 2, 2013, Pages 125-129

The influence of VKORC1 and CYP2C9 gene sequence variants on the stability of maintenance phase warfarin treatment

Author keywords

anticoagulant clinic; INR; pharmacogenetics; warfarin

Indexed keywords

CYTOCHROME P450 2C9; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG; VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1; WARFARIN;

EID: 84872326611     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2012.11.004     Document Type: Article
Times cited : (19)

References (30)
  • 1
    • 77952495872 scopus 로고    scopus 로고
    • Implementing genotype-guided antithrombotic therapy
    • R.L. Seip, J. Duconge, and G. Ruano Implementing genotype-guided antithrombotic therapy Future Cardiol 6 2010 409 424
    • (2010) Future Cardiol , vol.6 , pp. 409-424
    • Seip, R.L.1    Duconge, J.2    Ruano, G.3
  • 2
    • 33750004841 scopus 로고    scopus 로고
    • Warfarin: Almost 60 years old and still causing problems
    • M. Pirmohamed Warfarin: almost 60 years old and still causing problems Br J Clin Pharmacol 62 5 2006 509 511
    • (2006) Br J Clin Pharmacol , vol.62 , Issue.5 , pp. 509-511
    • Pirmohamed, M.1
  • 3
    • 33745206061 scopus 로고    scopus 로고
    • Frequency of CYP2C9 polymorphisms affecting warfarin metabolism in a large anticoagulant clinic cohort
    • M. Moridani, L. Fu, R. Selby, F. Yun, T. Sukovic, and B. Wong Frequency of CYP2C9 polymorphisms affecting warfarin metabolism in a large anticoagulant clinic cohort Clin Biochem 39 6 2006 606 612
    • (2006) Clin Biochem , vol.39 , Issue.6 , pp. 606-612
    • Moridani, M.1    Fu, L.2    Selby, R.3    Yun, F.4    Sukovic, T.5    Wong, B.6
  • 4
    • 27144539568 scopus 로고    scopus 로고
    • VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation
    • C. Geisen, M. Watzka, K. Sittinger, M. Steffens, L. Daugela, and E. Seifried VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation Thromb Haemost 94 4 2005 773 779
    • (2005) Thromb Haemost , vol.94 , Issue.4 , pp. 773-779
    • Geisen, C.1    Watzka, M.2    Sittinger, K.3    Steffens, M.4    Daugela, L.5    Seifried, E.6
  • 5
    • 59649117935 scopus 로고    scopus 로고
    • The largest prospective warfarin-treated cohort supports genetic forecasting
    • M. Wadelius, L.Y. Chen, J.D. Lindh, N. Eriksson, M.J. Ghori, and S. Bumpstead The largest prospective warfarin-treated cohort supports genetic forecasting Blood 113 2009 784 792
    • (2009) Blood , vol.113 , pp. 784-792
    • Wadelius, M.1    Chen, L.Y.2    Lindh, J.D.3    Eriksson, N.4    Ghori, M.J.5    Bumpstead, S.6
  • 6
    • 33846578240 scopus 로고    scopus 로고
    • VKORC1 and CYP2C9 genotypes and phenprocoumon anticoagulation status: Interaction between both genotypes affects dose requirement
    • T. Schalekamp, B.P. Brasse, J.F. Roijers, E. van Meegen, F.J. van der Meer, and E.M. van Wijk VKORC1 and CYP2C9 genotypes and phenprocoumon anticoagulation status: interaction between both genotypes affects dose requirement Clin Pharmacol Ther 81 2007 185 193
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 185-193
    • Schalekamp, T.1    Brasse, B.P.2    Roijers, J.F.3    Van Meegen, E.4    Van Der Meer, F.J.5    Van Wijk, E.M.6
  • 7
    • 22044433685 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity
    • L. Bodin, C. Verstuyft, D.A. Tregouet, A. Robert, L. Dubert, and C. Funck-Brentano Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity Blood 106 2005 135 140
    • (2005) Blood , vol.106 , pp. 135-140
    • Bodin, L.1    Verstuyft, C.2    Tregouet, D.A.3    Robert, A.4    Dubert, L.5    Funck-Brentano, C.6
  • 8
    • 57349097594 scopus 로고    scopus 로고
    • Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon
    • M. Beinema, J.R. Brouwers, T. Schalekamp, and B. Wilffert Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon Thromb Haemost 100 2008 1052 1057
    • (2008) Thromb Haemost , vol.100 , pp. 1052-1057
    • Beinema, M.1    Brouwers, J.R.2    Schalekamp, T.3    Wilffert, B.4
  • 9
    • 73049117322 scopus 로고    scopus 로고
    • Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy
    • N. Ferder, C.S. Eby, E. Deych, J.K. Harris, P.M. Ridker, and P. Milligan Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy J Thromb Haemost 8 1 2010 95 100
    • (2010) J Thromb Haemost , vol.8 , Issue.1 , pp. 95-100
    • Ferder, N.1    Eby, C.S.2    Deych, E.3    Harris, J.K.4    Ridker, P.M.5    Milligan, P.6
  • 10
    • 84863012482 scopus 로고    scopus 로고
    • Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy
    • B.D. Horne, P.A. Lenzini, M. Wadelius, A.L. Jorgensen, S.E. Kimmel, and P.M. Ridker Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy Thromb Haemost 107 2012 232 240
    • (2012) Thromb Haemost , vol.107 , pp. 232-240
    • Horne, B.D.1    Lenzini, P.A.2    Wadelius, M.3    Jorgensen, A.L.4    Kimmel, S.E.5    Ridker, P.M.6
  • 11
    • 47949086046 scopus 로고    scopus 로고
    • Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
    • B.F. Gage, C. Eby, J.A. Johnson, E. Deych, M.J. Rieder, and P.M. Ridker Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin Clin Pharmacol Ther 84 2008 326 331
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 326-331
    • Gage, B.F.1    Eby, C.2    Johnson, J.A.3    Deych, E.4    Rieder, M.J.5    Ridker, P.M.6
  • 13
    • 67349185332 scopus 로고    scopus 로고
    • Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin
    • K.N. Kangelaris, S. Bent, R.L. Nussbaum, D.A. Garcia, and J.A. Tice Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin J Gen Intern Med 24 2009 656 664
    • (2009) J Gen Intern Med , vol.24 , pp. 656-664
    • Kangelaris, K.N.1    Bent, S.2    Nussbaum, R.L.3    Garcia, D.A.4    Tice, J.A.5
  • 15
    • 84862777241 scopus 로고    scopus 로고
    • A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II)
    • J.L. Anderson, B.D. Horne, S.M. Stevens, S.C. Woller, K.M. Samuelson, and J.W. Mansfield A randomized and clinical effectiveness trial comparing two pharmacogenetic algorithms and standard care for individualizing warfarin dosing (CoumaGen-II) Circulation 125 2012 1997 2005
    • (2012) Circulation , vol.125 , pp. 1997-2005
    • Anderson, J.L.1    Horne, B.D.2    Stevens, S.M.3    Woller, S.C.4    Samuelson, K.M.5    Mansfield, J.W.6
  • 17
    • 3543028046 scopus 로고    scopus 로고
    • The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
    • L.E. Visser, R.H. van Schaik, M. van Vliet, P.H. Trienekens, P.A. De Smet, and A.G. Vulto The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon Thromb Haemost 92 2004 61 66
    • (2004) Thromb Haemost , vol.92 , pp. 61-66
    • Visser, L.E.1    Van Schaik, R.H.2    Van Vliet, M.3    Trienekens, P.H.4    De Smet, P.A.5    Vulto, A.G.6
  • 18
    • 62549128661 scopus 로고    scopus 로고
    • A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program
    • L. Poller, M. Keown, S. Ibrahim, G. Lowe, M. Moia, and A.G. Turpie A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program Thromb Haemost 101 2009 487 494
    • (2009) Thromb Haemost , vol.101 , pp. 487-494
    • Poller, L.1    Keown, M.2    Ibrahim, S.3    Lowe, G.4    Moia, M.5    Turpie, A.G.6
  • 19
    • 62549165827 scopus 로고    scopus 로고
    • Software support for 'doing the right thing right'
    • J.L. Dorsey Software support for 'doing the right thing right' Thromb Haemost 101 2009 413 414
    • (2009) Thromb Haemost , vol.101 , pp. 413-414
    • Dorsey, J.L.1
  • 20
    • 84865832599 scopus 로고    scopus 로고
    • Perceived stress predicts the stability of vitamin K-antagonist treatment of anticoagulant clinic patients
    • J. Skov, A. Leppin, E.M. Bladbjerg, J. Sidelmann, and J. Gram Perceived stress predicts the stability of vitamin K-antagonist treatment of anticoagulant clinic patients Thromb Haemost 108 2012 581 582
    • (2012) Thromb Haemost , vol.108 , pp. 581-582
    • Skov, J.1    Leppin, A.2    Bladbjerg, E.M.3    Sidelmann, J.4    Gram, J.5
  • 21
    • 80054741465 scopus 로고    scopus 로고
    • Plenty of pills: Polypharmacy prevails in patients of a Danish anticoagulant clinic
    • J. Skov, E.M. Bladbjerg, J. Sidelmann, M. Vamosi, and J. Jespersen Plenty of pills: polypharmacy prevails in patients of a Danish anticoagulant clinic Eur J Clin Pharmacol 67 2011 1169 1174
    • (2011) Eur J Clin Pharmacol , vol.67 , pp. 1169-1174
    • Skov, J.1    Bladbjerg, E.M.2    Sidelmann, J.3    Vamosi, M.4    Jespersen, J.5
  • 23
    • 84855979826 scopus 로고    scopus 로고
    • Genetic, clinical and behavioral determinants of vitamin K-antagonist dose - Explored through multivariable modelling and visualization
    • J. Skov, E.M. Bladbjerg, M.A. Rasmussen, J.J. Sidelmann, A. Leppin, and J. Jespersen Genetic, clinical and behavioral determinants of vitamin K-antagonist dose - explored through multivariable modelling and visualization Basic Clin Pharmacol Toxicol 110 2012 193 198
    • (2012) Basic Clin Pharmacol Toxicol , vol.110 , pp. 193-198
    • Skov, J.1    Bladbjerg, E.M.2    Rasmussen, M.A.3    Sidelmann, J.J.4    Leppin, A.5    Jespersen, J.6
  • 24
    • 33645635421 scopus 로고    scopus 로고
    • A rapid genotyping method for the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene
    • E. Hatch, E.A. Sconce, A.K. Daly, and F. Kamali A rapid genotyping method for the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene J Thromb Haemost 4 2006 1158 1159
    • (2006) J Thromb Haemost , vol.4 , pp. 1158-1159
    • Hatch, E.1    Sconce, E.A.2    Daly, A.K.3    Kamali, F.4
  • 26
    • 23044505564 scopus 로고    scopus 로고
    • Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
    • S. Schulman, and C. Kearon Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients J Thromb Haemost 3 2005 692 694
    • (2005) J Thromb Haemost , vol.3 , pp. 692-694
    • Schulman, S.1    Kearon, C.2
  • 27
    • 84860431509 scopus 로고    scopus 로고
    • An evaluation of gene-gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol
    • R.M. van Schie, A.M. Babajeff, T. Schalekamp, J.A. Wessels, S. le Cessie, and A. de Boer An evaluation of gene-gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol J Thromb Haemost 10 2012 767 772
    • (2012) J Thromb Haemost , vol.10 , pp. 767-772
    • Van Schie, R.M.1    Babajeff, A.M.2    Schalekamp, T.3    Wessels, J.A.4    Le Cessie, S.5    De Boer, A.6
  • 28
    • 78649342646 scopus 로고    scopus 로고
    • Patient characteristics associated with oral anticoagulation control: Results of the Veterans AffaiRs Study to Improve Anticoagulation (VARIA)
    • A.J. Rose, E.M. Hylek, A. Ozonoff, A.S. Ash, J.I. Reisman, and D.R. Berlowitz Patient characteristics associated with oral anticoagulation control: results of the Veterans AffaiRs Study to Improve Anticoagulation (VARIA) J Thromb Haemost 8 2010 2182 2191
    • (2010) J Thromb Haemost , vol.8 , pp. 2182-2191
    • Rose, A.J.1    Hylek, E.M.2    Ozonoff, A.3    Ash, A.S.4    Reisman, J.I.5    Berlowitz, D.R.6
  • 29
    • 77956977472 scopus 로고    scopus 로고
    • Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the RE-LY trial
    • L. Wallentin, S. Yusuf, M.D. Ezekowitz, M. Alings, M. Flather, and M.G. Franzosi Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial Lancet 376 2010 975 983
    • (2010) Lancet , vol.376 , pp. 975-983
    • Wallentin, L.1    Yusuf, S.2    Ezekowitz, M.D.3    Alings, M.4    Flather, M.5    Franzosi, M.G.6
  • 30
    • 33847006936 scopus 로고    scopus 로고
    • Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: Results from SPORTIF III and v
    • H.D. White, M. Gruber, J. Feyzi, S. Kaatz, H.F. Tse, and S. Husted Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: results from SPORTIF III and V Arch Intern Med 167 2007 239 245
    • (2007) Arch Intern Med , vol.167 , pp. 239-245
    • White, H.D.1    Gruber, M.2    Feyzi, J.3    Kaatz, S.4    Tse, H.F.5    Husted, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.