Inter-observer variance with the diagnosis of myelodysplastic syndromes (MDS) following the 2008 WHO classification

Annals of Hematology

Volumn 92, Issue 1, 2013, Pages 19-24

  Font, P ^a   Loscertales, J ^b   Benavente, C ^c   Bermejo, A ^d   Callejas, M ^e   Garcia Alonso, L ^f   Garcia Marcilla, A ^g   Gil, S ^h   Lopez Rubio, M ^e   Martin, E ^g   Munoz C ⁱ   Ricard, P ^j   Soto, C ^k   Balsalobre, P ^a   Villegas, A ^c  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^c HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^d HOSPITAL UNIVERSITARIO DE FUENLABRADA   (Spain)

^e HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

^f HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^g HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^h HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

ⁱ HOSPITAL UNIVERSITARIO INFANTA LEONOR   (Spain)

^j HOSPITAL UNIVERSITARIO FUNDACIÓN ALCORCÓN   (Spain)

^k Hospital UniversitarioFundación Jiménez Díaz   (Spain)

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Author keywords

Morphology; Myelodysplastic syndromes (MDS); WHO classification

Indexed keywords

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE CLASSIFICATION; HUMAN; HUMAN CELL; INTERRATER RELIABILITY; MAJOR CLINICAL STUDY; MORPHOLOGY; MYELODYSPLASTIC SYNDROME; OBSERVER VARIATION; PRIORITY JOURNAL; REFRACTORY ANEMIA WITH EXCESS BLASTS; REFRACTORY ANEMIA WITH RINGED SIDEROBLASTS; REFRACTORY CYTOPENIA WITH MULTILINEAGE DYSPLASIA; REFRACTORY CYTOPENIA WITH UNILINEAGE DYSPLASIA; REPRODUCIBILITY; WORLD HEALTH ORGANIZATION;

ANEMIA, REFRACTORY, WITH EXCESS OF BLASTS; BIOPSY; BONE MARROW; BONE MARROW EXAMINATION; CELL LINEAGE; CHROMOSOME ABERRATIONS; CYTOGENETIC ANALYSIS; HEMATOLOGY; HUMANS; LABORATORIES, HOSPITAL; LABORATORY PROFICIENCY TESTING; MYELODYSPLASTIC SYNDROMES; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; SINGLE-BLIND METHOD; SPAIN; WORLD HEALTH ORGANIZATION;

EID: 84872320058     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-012-1565-4     Document Type: Article

References (16)

1. Tefferi A, Vardiman JW (2009) Myelodysplastic syndromes. N Engl J Med 361:1872-1885
2. Brunning RD, Orazi A, Germing U, Le Beau MM, Porwit A, Baumann I, Vardiman JW, Hellstrom-Lindberg E (2008) Myelodysplastic syndromes/neoplasms, overview. In: Swerdlow SH, Campo E, Harris NL et al (eds) World Health Organization classification of tumours of haematopoietic and lymphoid tissues, 4th edn. IARC, Lyon, pp 88-93
3. Brunning RD, Bennett JM, Flandrin G, Matutes E, Head D, Vardiman JW, Harris NL (2001) Myelodysplastic syndromes. Introduction. In: Jaffe ES, Harris NL, Stein H, Vardiman JW (eds) World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. IARC, Lyon, pp 63-67
4. Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A et al (2009) The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 114:937-951
5. Howe RB, Porwit-MacDonald A, Wanat R, Tehranchi R, Hellström- Lindberg E (2004) The WHO classification of MDS does make a difference. Blood 103:3265-3270
6. Naqvi K, Jabbour E, Bueso-Ramos C, Pierce S, Borthakur G, Estrov Z et al (2011) Implications of discrepancy in morphologic diagnosis of myelodysplastic syndrome between referral and tertiary care centers. Blood 118:4690-4693
7. Greenberg P, Cox C, LeBeau MM, Fenaux P, Morel P, Sanz G et al (1997) International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 89:2079-2088
8. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, Sultan C (1982) French-American-British (FAB) Cooperative Group. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51:189-199
9. Verburgh E, Achten R, Louw VJ, Brusselmans C, Delforge M, Boogaerts M et al (2007) A new disease categorization of low-grade myelodysplastic syndromes based on the expression of cytopenia and dysplasia in one versus more than one lineage improves on the WHO classification. Leukemia 21:668-677
10. Mufti GJ, Bennett JM, Goasguen J, Bain BJ, Baumann I, Brunning R et al (2008) Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts. Haematologica 93:1712-1717
11. Malcovati L, Germing U, Kuendgen A, Della Porta MG, Pascutto C, Invernizzi R et al (2007) Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes. J Clin Oncol 25:3503-3510
12. Matsuda A, Germing U, Jinnai I, Iwanaga M, Misumi M, Kuendgen A et al (2007) Improvement of criteria for refractory cytopenia with multilineage dysplasia according to the WHO classification based on prognostic significance of morphological features in patients with refractory anemia according to the FAB classification. Leukemia 21:678-686
13. Germing U, Gattermann N, Strupp C, Aivado M, Aul C (2000) Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients. Leuk Res 24:983-992
14. Germing U, Strupp C, Kuendgen A, Isa S, Knipp S, Hildebrandt B et al (2006) Prospective validation of the WHO proposals for the classification of myelodysplastic syndromes. Haematologica 91:1596-1604
15. Patnaik MM, Hanson CA, Sulai NH, Hodnefield JM, Knudson RA, Ketterling RP et al (2012) Prognostic irrelevance of ring sideroblast percentage in World Health Organization defined myelodysplastic syndromes without excess blasts. Blood 119:5674-5677
16. Kantarjian H, O'Brien S, Ravandi F, Cortes J, Shan J, Bennett JM et al (2008) Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System. Cancer 113:1351-1361