Isolation and purification of paeoniflorin and albiflorin from radix paeoniae rubra by high-speed counter-current chromatography

Journal of Liquid Chromatography and Related Technologies

Volumn 36, Issue 4, 2013, Pages 419-427

  Huang, Jieyun ^a,b   Xu, Xinjun ^a,b   Xie, Chunyan ^a,b   Xie, Zhisheng ^a,b   Yang, Mei ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangdong Technology Research Center for Advanced Chinese Medicine   (China)

Author keywords

albiflorin; HSCCC; isolation; paeoniflorin; purification; Radix Paeoniae Rubra

Indexed keywords

ALBIFLORIN; HSCCC; ISOLATION; PAEONIFLORIN; RADIX PAEONIAE RUBRA;

ALCOHOLS; CHROMATOGRAPHY;

PURIFICATION;

ACETIC ACID ETHYL ESTER; ALBIFLORIN; BUTANOL; PAEONIA RADIX; PAEONIFLORIN; SOLVENT; WATER;

ARTICLE; CHEMICAL STRUCTURE; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; DRUG PURIFICATION; DRUG PURITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH SPEED COUNTER CURRENT CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET RADIATION;

EID: 84872314069     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2012.657737     Document Type: Article

References (12)

1. Xu, S. J.; Yang, L.; Tian, R. T.; Wang, Z. T.; Liu, Z. J.; Xie, P. S.; Feng, Q. R. Species Differentiation and Quality Assessment of Radix Paeoniae Rubra (Chi-shao) by Means of High-Performance Liquid Chromatographic Fingerprint. J. Chromatogr. A 2009, 1216 (11), 2163-2168.
2. Wang, C. H.; Wang, R.; Cheng, X. M.; He, Y. Q.; Wang, Z. T.; Wu, C.; Cao, J. Comparative Pharmacokinetic Study of Paeoniflorin after Oral Administration of Decoction of Radix Paeoniae Rubra and Radix Paeoniae Alba in Rats. J. Ethnopharmacol 2008, 117 (3), 467-472.
3. Ruan, J. L.; Zhao, Z. X.; Zeng, Q. Z.; Qian, Z. M. Recent Advances in Study of Components and Pharmacological Roles of Radix Paeoniae Rubra. Chinese Pharmacological Bulletin. 2003, 19 (9), 965-970.
4. Ye, J. F.; Duan, H. L.; Yang, X. M.; Yan, W.; Zheng, X. Anti-Thrombosis Effect of Paeoniflorin: Evaluated in a Photochemical Reaction Thrombosis Model In Vivo. Planta Medica. 2001, 67 (8), 766-768.
5. Sun, A. L.; Zhang Y. Q.; Li, A. F.; Meng, Z. L.; Liu, R. M. Extraction and Preparative Purification of Tanshinones from Salvia miltiorrhiza Bunge by High-Speed Counter-Current Chromatography. J. Chromatogr. B. 2011, 879, 1899-1904.
6. Zhang, S. J.; Wang, M. Y.; Wang, C. H. Preparative Separation and Purification of Alkaloids from Rhizoma coptidis by High-Speed Counter-Current Chromatography. Sep. Purif. Technol. 2011, 76, 428-431.
7. Chen, F.; Lu, H. T.; Jiang, Y. Purification of Paeoniflorin from Paeonia lactiflora Pall. by High-Speed Counter-Current Chromatography. J. Chromatogr. A 2004, 1040 (2), 205-208.
8. Li, L.; Tsao, R.; Yang, R.; Liu, C.; Young, J. C.; Zhu, H. Isolation and Purification of Phenylethanoid Glycosides from Cistanche deserticola by High-Speed Counter-Current Chromatography. Food Chem. 2008, 108 (2), 702-710.
9. Ito, Y. Golden Rules and Pitfalls in Selecting Optimum Conditions for High-Speed Counter-Current Chromatography. J. Chromatogr. A. 2005, 1065 (2), 145-168.
10. Zhang, X. Y.; Wang, J. H.; Li, X. A Study on the NMR Spectrum of Monoterpene glucosides from Paeonia lactiflora Pall. J. Shenyang Pharm. U 2001, 18 (1), 27-29.
11. Mkaneda, Y. Iitaka, S. Shibata Chemical Studies on the Oriental Plant Drugs-XXXII the Absolute Structures of Paeoniflorin, Albiflorin, Oxypaeoniflorin and Benzoylpaeoniflorin Isolation from Chinese paeony Root. Tetrahedron. 1972, 28 (16), 4309-4317.
12. Song, Z. H.; Wang, B. D.; Ba, H.; Tong, X. T.; Zhu, D. Y.; Jiang, F. X. Studies on Chemical Constituents in Root of Paeonia sinjiangensis. China J. Chin. Mater. Med. 2004, 29 (8), 748-751.