C9ORF72 repeat expansions not detected in a group of patients with schizophrenia

Neurobiology of Aging

Volumn 34, Issue 4, 2013, Pages 1309.e9-1309.e10

  Huey, Edward D ^a,b   Nagy, Peter L ^b   Rodriguez Murillo, Laura ^b   Manoochehri, Masood ^a   Goldman, Jill ^a,b   Lieberman, Jeffrey ^b   Karayiorgou, Maria ^b   Mayeux, Richard ^a,b  

^a Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^b NONE   (United States)

Author keywords

C9ORF72 repeat expansion; FTLD; Psychosis; Schizophrenia

Indexed keywords

DNA;

ALLELE; ARTICLE; C9ORF72 GENE; CHROMOSOME 9; CONTROLLED STUDY; DNA SCREENING; GENE; GENETIC ASSOCIATION; GENETIC RISK; HEXANUCLEOTIDE REPEAT; HUMAN; MAJOR CLINICAL STUDY; NUCLEOTIDE REPEAT; OPEN READING FRAME; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA;

EID: 84872301861     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.08.011     Document Type: Article

References (11)

1. Collins J.S., Schwartz C.E. Detecting polymorphisms and mutations in candidate genes. Am. J. Hum. Genet. 2002, 71:1251-1252.
2. DeJesus-Hernandez M., Mackenzie I.R., Boeve B.F., Boxer A.L., Baker M., Rutherford N.J., Nicholson A.M., Finch N.A., Flynn H., Adamson J., Kouri N., Wojtas A., Sengdy P., Hsiung G.Y., Karydas A., Seeley W.W., Josephs K.A., Coppola G., Geschwind D.H., Wszolek Z.K., Feldman H., Knopman D.S., Petersen R.C., Miller B.L., Dickson D.W., Boylan K.B., Graff-Radford N.R., Rademakers R. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72:245-256.
3. Momeni P., DeTucci K., Straub R.E., Weinberger D.R., Davies P., Grafman J., Hardy J., Huey E.D. Progranulin (GRN) in two siblings of a Latino family and in other patients with schizophrenia. Neurocase 2010, 16:273-279.
4. Nurnberger J.I., Blehar M.C., Kaufmann C.A., York-Cooler C., Simpson S.G., Harkavy-Friedman J., Severe J.B., Malaspina D., Reich T. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch. Gen. Psychiatry 1994, 51:849-859. discussion 63-64.
5. Pick A. Ueber primare chronische Demenz (so. Dementia praecox) im jugendlichen Alter. Prager medicinische Wochenschrif 1891, 16:312-315.
6. Rademakers R. C9orf72 repeat expansions in patients with ALS and FTD. Lancet Neurol. 2012, 11:297-298.
7. Renton A.E., Majounie E., Waite A., Simon-Sanchez J., Rollinson S., Gibbs J.R., Schymick J.C., Laaksovirta H., van Swieten J.C., Myllykangas L., Kalimo H., Paetau A., Abramzon Y., Remes A.M., Kaganovich A., Scholz S.W., Duckworth J., Ding J., Harmer D.W., Hernandez D.G., Johnson J.O., Mok K., Ryten M., Trabzuni D., Guerreiro R.J., Orrell R.W., Neal J., Murray A., Pearson J., Jansen I.E., Sondervan D., Seelaar H., Blake D., Young K., Halliwell N., Callister J.B., Toulson G., Richardson A., Gerhard A., Snowden J., Mann D., Neary D., Nalls M.A., Peuralinna T., Jansson L., Isoviita V.M., Kaivorinne A.L., Hölttä-Vuori M., Ikonen E., Sulkava R., Benatar M., Wuu J., Chiò A., Restagno G., Borghero G., Sabatelli M., ITALSGEN Consortium, Heckerman D., Rogaeva E., Zinman L., Rothstein J.D., Sendtner M., Drepper C., Eichler E.E., Alkan C., Abdullaev Z., Pack S.D., Dutra A., Pak E., Hardy J., Singleton A., Williams N.M., Heutink P., Pickering-Brown S., Morris H.R., Tienari P.J., Traynor B.J. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011, 72:257-268.
8. Schoder D., Hannequin D., Martinaud O., Opolczynski G., Guyant-Marechal L., Le Ber I., Campion D. Morbid risk for schizophrenia in first-degree relatives of people with frontotemporal dementia. Br. J. Psychiatry 2010, 197:28-35.
9. Snowden J.S., Rollinson S., Thompson J.C., Harris J.M., Stopford C.L., Richardson A.M., Jones M., Gerhard A., Davidson Y.S., Robinson A., Gibbons L., Hu Q., DuPlessis D., Neary D., Mann D.M., Pickering-Brown S.M. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. Brain 2012, 135:693-708.
10. Velakoulis D., Walterfang M., Mocellin R., Pantelis C., McLean C. Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases. Br. J. Psychiatry 2009, 194:298-305.
11. Ziauddeen H., Dibben C., Kipps C., Hodges J.R., McKenna P.J. Negative schizophrenic symptoms and the frontal lobe syndrome: one and the same?. Eur. Arch. Psychiatry Clin. Neurosci. 2011, 261:59-67.