Prescription acetaminophen ingestions associated with hepatic injury and death

Journal of Community Health

Volumn 37, Issue 6, 2012, Pages 1249-1252

  Martinez, Richard M ^a   Nordt, Sean Patrick ^b   Cantrell, F Lee ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c California Poison Control Center   (United States)

Author keywords

Acetaminophen; Poisoning; Prescription

Indexed keywords

PARACETAMOL; PRESCRIPTION DRUG;

ADULT; AGED; ARTICLE; CHEMISTRY; DEATH; FACTUAL DATABASE; FEMALE; HUMAN; MALE; MIDDLE AGED; POISON CENTER; RETROSPECTIVE STUDY; TOXIC HEPATITIS; UNITED STATES;

ACETAMINOPHEN; ADULT; AGED; AGED, 80 AND OVER; CALIFORNIA; DATABASES, FACTUAL; DEATH; DRUG-INDUCED LIVER INJURY; FEMALE; HUMANS; MALE; MIDDLE AGED; POISON CONTROL CENTERS; PRESCRIPTION DRUGS; RETROSPECTIVE STUDIES;

EID: 84872268262     PISSN: 00945145     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10900-012-9563-y     Document Type: Article

References (13)

1. Black, M. (1984). Acetaminophen hepatoxicity. Annual Review of Medicine, 35, 577-593.
2. Schiodt, F. V., Rochling, F. A., Casey, D. L., et al. (1997). Acetaminophen toxicity in an urban county hospital. New England Journal of Medicine, 337, 1112-1117.
3. Larson, A. M., Polson, J., Fontana, R. J., et al. (2005). Acet-aminophen-induced acute liver failure: results of a United States multicenter, prospective study. Hepatology, 42(6), 1364-1372.
4. Craig, D. G., Bates, C. M., Davidson, J. S., Martin, K. G., Hayes, P. C., & Simpson, K. J. (2011). Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity. British Journal of Clinical Pharmacology, 71(2), 273-282.
5. United States Food and Drug Administration. FDA Drug Safety Communication: Prescription Acetaminophen Products to be Limited to 325 mg Per Dosage Unit. http://www.fda.gov/Drugs/DrugSafety/ucm239821.htm (accessed 2011 Oct 20).
6. Green, T. J., Sivilotti, M. L., Langmann, C., et al. (2010). When do the aminotransferases rise after acute acetaminophen overdose? Clinical toxicology, 48(8), 787-792.
7. th Annual Report. Clinical toxicology, 47(10), 911-1084.
8. Drug Topics. Drug Topics releases top branded and generic drug lists. http://drugtopics.modernmedicine.com/drugtopics/article/articleDetail.jsp?id= 727261 (accessed 2011 Oct 20).
9. Dart, R. C., Erdman, A. R., Olson, K. R., et al. (2006). Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management. Clinical toxicology (Philadelphia, Pa.), 44(1), 1-18.
10. Harrison, P. M., Keays, R., Bray, G. P., et al. (1990). Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet, 335, 1572-1573.
11. Keays, R., Harrison, P. M., Wendon, J. A., et al. (1991). Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trail. BMJ, 303(6809), 1026-1029.
12. Hornsby, L. B., Whitley, H. P., Hester, E. K., et al. (2010). Survey of patient knowledge related to acetaminophen recognition, dosing, and toxicity. Journal American Pharmacists Association, 50(4), 485-492.
13. Fosnocht, D., Taylor, J. R., & Caravati, E. M. (2008). Emergency department knowledge concerning acetaminophen (paracetamol) in over-The-counter and prescription analgesics. Emergency Medical Journal, 25(4), 213-216.