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Volumn 46, Issue 12, 2012, Pages 1627-1636

Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: A multicenter, in vitro study;Efectos de dabigatran en el cociente internacional normalizado, tiempo de tromboplastina parcial activada, tiempo de trombina y fibrinógeno: Estudio multicéntrico, in vitro

Author keywords

Activated partial thromboplastin time; Dabigatran; Fibrinogen; International normalized ratio; Thrombin time

Indexed keywords

DABIGATRAN; FIBRINOGEN; REAGENT;

EID: 84872258441     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1R179     Document Type: Article
Times cited : (97)

References (25)
  • 1
    • 79954456496 scopus 로고    scopus 로고
    • Dabigatran etexilate: A new oral thrombin inhibitor
    • doi: 10.1161/CIRCULATIONAHA.110.004424
    • Hankey GJ, Eikelboom JW. Dabigatran etexilate: a new oral thrombin inhibitor. Circulation 2011;123:1436-50. doi: 10.1161/CIRCULATIONAHA.110.004424
    • (2011) Circulation , vol.123 , pp. 1436-1450
    • Hankey, G.J.1    Eikelboom, J.W.2
  • 2
    • 77952167209 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor
    • doi: 10.1177/1076029609343004
    • Stangier J, Clemens A. Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor. Clin Appl Thromb Hemost 2009;15(suppl 1):9S-16S. doi: 10.1177/1076029609343004
    • (2009) Clin Appl Thromb Hemost , vol.15 , Issue.1 SUPPL.
    • Stangier, J.1    Clemens, A.2
  • 3
    • 70349306707 scopus 로고    scopus 로고
    • RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation
    • doi: 10.1056/NEJMoa0905561
    • Connolly SJ, Ezekowitz MD, Yusuf S, et al.; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361:1139-51. doi: 10.1056/NEJMoa0905561
    • (2009) N Engl J Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 4
    • 77953791161 scopus 로고    scopus 로고
    • RE-MOBILIZE, RE-MODEL, RE-NOVATE Steering Committees. Dabigatran versus enoxaparin for prevention of venous thromboembolism after hip or knee arthroplasty: A pooled analysis of three trials
    • doi: 10.1016/j.thromres.2010.03.021
    • Friedman RJ, Dahl OE, Rosencher N, et al.; RE-MOBILIZE, RE-MODEL, RE-NOVATE Steering Committees. Dabigatran versus enoxaparin for prevention of venous thromboembolism after hip or knee arthroplasty: a pooled analysis of three trials. Thromb Res 2010;126:175-82. doi: 10.1016/j.thromres.2010.03.021
    • (2010) Thromb Res , vol.126 , pp. 175-182
    • Friedman, R.J.1    Dahl, O.E.2    Rosencher, N.3
  • 5
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • RE-COVER Study Group doi: 10.1056/NEJMoa0906598
    • Schulman S, Kearon C, Kakkar AK, et al.; RE-COVER Study Group. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009;361:2342-52. doi: 10.1056/NEJMoa0906598
    • (2009) N Engl J Med , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 6
    • 79958077792 scopus 로고    scopus 로고
    • Drug and dietary interactions of warfarin and novel oral anticoagulants: An update
    • doi: 10.1007/s11239-011-0561-1
    • Nutescu E, Chuatrisorn I, Hellenbart E. Drug and dietary interactions of warfarin and novel oral anticoagulants: an update. J Thromb Thrombolysis 2011;31:326-43. doi: 10.1007/s11239-011-0561-1
    • (2011) J Thromb Thrombolysis , vol.31 , pp. 326-343
    • Nutescu, E.1    Chuatrisorn, I.2    Hellenbart, E.3
  • 7
    • 77952737706 scopus 로고    scopus 로고
    • Drug and dietary interactions of the new and emerging oral anticoagulants
    • doi: 10.1111/j.1742-1241.2009.02286.x
    • Walenga JM, Adiguzel C. Drug and dietary interactions of the new and emerging oral anticoagulants. Int J Clin Pract 2010;64:956-67. doi: 10.1111/j.1742-1241.2009.02286.x
    • (2010) Int J Clin Pract , vol.64 , pp. 956-967
    • Walenga, J.M.1    Adiguzel, C.2
  • 8
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • doi: 10.1160/TH09-11-0758
    • van Ryn J, Stangier J, Haertter S, et al. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010;103: 1116-27. doi: 10.1160/TH09-11-0758
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 9
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
    • doi: 10.1111/j.1365-2125.2007.02899.x
    • Stangier J, Rathgen K, Stähle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007;64:292-303. doi: 10.1111/j.1365-2125.2007.02899.x
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 292-303
    • Stangier, J.1    Rathgen, K.2    Stähle, H.3    Gansser, D.4    Roth, W.5
  • 10
    • 17644400166 scopus 로고    scopus 로고
    • Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
    • doi: 10.1177/0091270005274550
    • Stangier J, Eriksson BI, Dahl OE, et al. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol 2005; 45:555-63. doi: 10.1177/0091270005274550
    • (2005) J Clin Pharmacol , vol.45 , pp. 555-563
    • Stangier, J.1    Eriksson, B.I.2    Dahl, O.E.3
  • 11
    • 84872229284 scopus 로고    scopus 로고
    • FDA, for the September 20, 2010, meeting of the cardiovascular and renal drugs advisory committee, (accessed 2012 Feb 16)
    • FDA. Briefing information, dabigatran etexilate mesylate capsules, for the September 20, 2010, meeting of the cardiovascular and renal drugs advisory committee www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/CardiovascularandRenalDrugsAdvisoryCommittee/UCM247244.pdf (accessed 2012 Feb 16).
    • Briefing Information, Dabigatran Etexilate Mesylate Capsules
  • 12
    • 79851482951 scopus 로고    scopus 로고
    • Expert group on coagulation of the external quality assurance in laboratory medicine in Sweden. Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
    • doi: 10.1160/TH10-06-0342
    • Lindahl TL, Baghaei F, Blixter IF, et al. Expert group on coagulation of the external quality assurance in laboratory medicine in Sweden. Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays. Thromb Haemost 2011;105:371-8. doi: 10.1160/TH10-06-0342
    • (2011) Thromb Haemost , vol.105 , pp. 371-378
    • Lindahl, T.L.1    Baghaei, F.2    Blixter, I.F.3
  • 13
    • 34447522035 scopus 로고    scopus 로고
    • In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
    • doi: 10.1160/TH07-03-0183
    • Wienen W, Stassen JM, Priepke H, Ries UJ, Hauel N. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate. Thromb Haemost 2007;98:155-62. doi: 10.1160/TH07-03-0183
    • (2007) Thromb Haemost , vol.98 , pp. 155-162
    • Wienen, W.1    Stassen, J.M.2    Priepke, H.3    Ries, U.J.4    Hauel, N.5
  • 14
    • 79955480110 scopus 로고    scopus 로고
    • Coagulation parameters in patients receiving dabigatran etexilate or rivaroxaban: Two observational studies in patients undergoing total hip or total knee replacement
    • doi: 10.1016/j.thromres.2011.01.001
    • Freyburger G, Macouillard G, Labrouche S, Sztark F. Coagulation parameters in patients receiving dabigatran etexilate or rivaroxaban: two observational studies in patients undergoing total hip or total knee replacement. Thromb Res 2011;127:457-65. doi: 10.1016/j.thromres.2011.01.001
    • (2011) Thromb Res , vol.127 , pp. 457-465
    • Freyburger, G.1    Macouillard, G.2    Labrouche, S.3    Sztark, F.4
  • 15
    • 77249146517 scopus 로고    scopus 로고
    • Laboratory monitoring of new anticoagulants
    • doi: 10.1002/ajh.21607
    • Castellone DD, Van Cott EM. Laboratory monitoring of new anticoagulants. Am J Hematol 2010;85:185-7. doi: 10.1002/ajh.21607
    • (2010) Am J Hematol , vol.85 , pp. 185-187
    • Castellone, D.D.1    van Cott, E.M.2
  • 16
    • 79954534386 scopus 로고    scopus 로고
    • Laboratory assessment of new anticoagulants
    • doi: 10.1515/CCLM.2011.134
    • Samama MM, Guinet C. Laboratory assessment of new anticoagulants. Clin Chem Lab Med 2011;49:761-72. doi: 10.1515/CCLM.2011.134
    • (2011) Clin Chem Lab Med , vol.49 , pp. 761-772
    • Samama, M.M.1    Guinet, C.2
  • 17
    • 77952005024 scopus 로고    scopus 로고
    • Anesthetic concerns for patients with coagulopathy
    • doi: 10.1097/ACO.0b013e328339480a
    • Levy JH, Azran M. Anesthetic concerns for patients with coagulopathy. Curr Opin Anaesthesiol 2010;23:400-5. doi: 10.1097/ACO.0b013e328339480a
    • (2010) Curr Opin Anaesthesiol , vol.23 , pp. 400-405
    • Levy, J.H.1    Azran, M.2
  • 18
    • 79960798870 scopus 로고    scopus 로고
    • Potential inaccuracy of point-of-care INR in dabigatran- treated patients
    • doi: 10.1345/aph.1Q105
    • Baruch L, Sherman O. Potential inaccuracy of point-of-care INR in dabigatran- treated patients. Ann Pharmacother 2011;45:e40. doi: 10.1345/aph.1Q105
    • (2011) Ann Pharmacother , vol.45
    • Baruch, L.1    Sherman, O.2
  • 19
    • 84863811351 scopus 로고    scopus 로고
    • Dabigatran falsely elevates point of care international normalized ratio results
    • doi:10.1016/j.amjmed.2011.02.009
    • Deremer CE, Gujral JS, Thornton JW, Sorrentino RA. Dabigatran falsely elevates point of care international normalized ratio results. Am J Med 2011;124:e5-6. doi:10.1016/j.amjmed.2011.02.009
    • (2011) Am J Med , vol.124
    • Deremer, C.E.1    Gujral, J.S.2    Thornton, J.W.3    Sorrentino, R.A.4
  • 21
    • 84858966373 scopus 로고    scopus 로고
    • Interpretation of point-of-care INR results in patients treated with dabigatran
    • doi: 10.1016/j.amjmed.2011.10.017
    • van Ryn J, Baruch L, Clemens A. Interpretation of point-of-care INR results in patients treated with dabigatran. Am J Med 2012;125:417-20. doi: 10.1016/j.amjmed.2011.10.017
    • (2012) Am J Med , vol.125 , pp. 417-420
    • van Ryn, J.1    Baruch, L.2    Clemens, A.3
  • 23
    • 34447503698 scopus 로고    scopus 로고
    • Monitoring direct thrombin inhibitors with a plasma diluted thrombin time
    • doi: 10.1160/TH06-10-0607
    • Love JE, Ferrell C, Chandler WL. Monitoring direct thrombin inhibitors with a plasma diluted thrombin time. Thromb Haemost 2007;98:234-42. doi: 10.1160/TH06-10-0607
    • (2007) Thromb Haemost , vol.98 , pp. 234-242
    • Love, J.E.1    Ferrell, C.2    Chandler, W.L.3
  • 24
    • 84856593171 scopus 로고    scopus 로고
    • Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
    • doi: 10.1097/MBC.0b013e32834f1b0c
    • Stangier J, Feuring M. Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran. Blood Coagul Fibrinolysis 2012;23:138-43. doi: 10.1097/MBC.0b013e32834f1b0c
    • (2012) Blood Coagul Fibrinolysis , vol.23 , pp. 138-143
    • Stangier, J.1    Feuring, M.2
  • 25
    • 46949089593 scopus 로고    scopus 로고
    • The use of ecarin chromogenic assay and prothrombinase induced clotting time in the monitoring of lepirudin for the treatment of heparin-induced thrombocytopenia
    • doi: 10.1111/j.1365-2141.2008.07204.x
    • Guy S, Kitchen S, Laidlaw S, Cooper P, Woolley A, Maclean R. The use of ecarin chromogenic assay and prothrombinase induced clotting time in the monitoring of lepirudin for the treatment of heparin-induced thrombocytopenia. Br J Haematol 2008;142:466-8. doi: 10.1111/j.1365-2141.2008.07204.x
    • (2008) Br J Haematol , vol.142 , pp. 466-468
    • Guy, S.1    Kitchen, S.2    Laidlaw, S.3    Cooper, P.4    Woolley, A.5    Maclean, R.6


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