Arterial stiffness: Detection and consequences in cognitive impairment and dementia of the elderly

Journal of Alzheimer's Disease

Volumn 32, Issue 3, 2012, Pages 541-549

  Rabkin, Simon W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alzheimer's disease; arterial stiffness; cognitive impairment; dementia

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; COLLAGEN; CREATININE; DIHYDROPYRIDINE; DIURETIC AGENT; ELASTIN; FIBRONECTIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTEOGLYCAN;

AEROBIC EXERCISE; AGE DISTRIBUTION; AGING; ARTERIAL STIFFNESS; BODY MASS; BRAIN DISEASE; DAILY LIFE ACTIVITY; DEMENTIA; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; EDUCATIONAL STATUS; ELDERLY CARE; HUMAN; HYPERTENSION; MEAN ARTERIAL PRESSURE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULSE WAVE; REVIEW; VASOCONSTRICTION;

EID: 84872257634     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120757     Document Type: Review

References (64)

1. de la Torre JC (2004) Is alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics. Lancet Neurol 3, 184-190. (Pubitemid 38232669)
2. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson I, Struijker-Boudier H, European Network for Non-invasive Investigation of Large A (2006) Expert consensus document on arterial stiffness: Methodological issues and clinical applications. Eur Heart J 27, 2588-2605. (Pubitemid 44627304)
3. Adji A, O'RourkeMF, NamasivayamM(2011) Arterial stiffness, its assessment, prognostic value, and implications for treatment. Am J Hypertens 24, 5-17.
4. NicholsWW, O'Rouke MF, Vlackopoulos C (2011) McDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles, Hodder Arnold, London
5. Tanaka H, Munakata M, Kawano Y, Ohishi M, Shoji T, Sugawara J, Tomiyama H, Yamashina A, Yasuda H, Sawayama T, Ozawa T (2009) Comparison between carotid-femoral and brachial-Ankle pulse wave velocity as measures of arterial stiffness. J Hypertens 27, 2022-2027.
6. O'Rourke MF, Hashimoto J (2007) Mechanical factors in arterial aging: A clinical perspective. J Am Col Cardiol 50, 1-13. (Pubitemid 46963521)
7. Lakatta EG (2003) Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part III: Cellular and molecular clues to heart and arterial aging. Circulation 107, 490-497. (Pubitemid 36158054)
8. Lakatta EG, Levy D (2003) Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part I: Aging arteries: A "set up" for vascular disease. Circulation 107, 139-146. (Pubitemid 36070946)
9. Rabkin SW, Jarvie G (2011) Comparison of vascular stiffness in vascular dementia, alzheimer dementia and cognitive impairment. Blood Pressure 20, 274-283.
10. Nagai K, Akishita M, Machida A, Sonohara K, Ohni M, Toba K (2004) Correlation between pulse wave velocity and cognitive function in nonvascular dementia. J Am Geriatrics Soc 52, 1037-1038. (Pubitemid 38789091)
11. Scuteri A, Brancati AM, GianniW, Assisi A, VolpeM(2005) Arterial stiffness is an independent risk factor for cognitive impairment in the elderly:Apilot study. J Hypertens 23, 1211-1216. (Pubitemid 40862725)
12. Hanon O, Haulon S, Lenoir H, Seux ML, Rigaud AS, Safar M, Girerd X, Forette F (2005) Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss. Stroke 36, 2193-2197. (Pubitemid 41429244)
13. Abbatecola AM, Barbieri M, Rizzo MR, Grella R, LaietaMT, Quaranta E, Molinari AM, Cioffi M, Fioretto P, Paolisso G (2008) Arterial stiffness and cognition in elderly persons with impaired glucose tolerance and microalbuminuria. J Gerontol Series A Biol Sci Med Sci 63, 991-996.
14. Sugawara N, Yasui-Furukori N, Umeda T, Kaneda A, Sato Y, Takahashi I, Matsuzaka M, Danjo K, Nakaji S, Kaneko S (2010) Comparison of ankle-Brachial pressure index and pulse wave velocity as markers of cognitive function in a community-Dwelling population. BMC Psych 10, 46.
15. Kim YS, Kim DH, Choi BH, Sohn EH, Lee AY (2009) Relationship between brachial-Ankle pulse wave velocity and cognitive function in an elderly community-Dwelling population with metabolic syndrome. Arch Gerontol Geriatr 49, 176-179.
16. Komai N, Ohishi M, Kaibe M, Jinno T, Katsuya T, Higaki J, Rakugi H, Inoue T, Ogihara T (2002) Arterial pulse wave velocity in elderly patients with dementia. Geriatr Gerontol Int 2, 193-198.
17. Mitchell GF, van Buchem MA, Sigurdsson S, Gotal JD, Jonsdottir MK, Kjartansson O, Garcia M, Aspelund T, Harris TB, Gudnason V, Launer LJ (2011) Arterial stiffness, pressure and flow pulsatility and brain structure and function: The Age, Gene/Environment Susceptibility-Reykjavik study. Brain 134, 3398-3407.
18. Watson NL, Sutton-Tyrrell K, Rosano C, Boudreau RM, Hardy SE, Simonsick EM, Najjar SS, Launer LJ, Yaffe K, Atkinson HH, Satterfield S, Newman AB (2011) Arterial stiffness and cognitive decline in well-functioning older adults. J Gerontol Series A Biol Sci Med Sci 66, 1336-1342.
19. Waldstein SR, Rice SC, Thayer JF, Najjar SS, Scuteri A, Zonderman AB (2008) Pulse pressure and pulse wave velocity are related to cognitive decline in the Baltimore Longitudinal Study of Aging. Hypertension 51, 99-104. (Pubitemid 350307110)
20. Elias MF, Robbins MA, Budge MM, Abhayaratna WP, Dore GA, Elias PK (2009) Arterial pulse wave velocity and cognition with advancing age. Hypertension 53, 668-673.
21. PoelsMM,van Oijen M, Mattace-Raso FU, Hofman A,Koudstaal PJ,Witteman JC, BretelerMM(2007) Arterial stiffness, cognitive decline, and risk of dementia: The rotterdam study. Stroke 38, 888-892. (Pubitemid 46568448)
22. Muller M, Grobbee DE, Aleman A, Bots M, van der Schouw YT (2007) Cardiovascular disease and cognitive performance in middle-Aged and elderly men. Atherosclerosis 190, 143-149. (Pubitemid 44908308)
23. Triantafyllidi H, Arvaniti C, Lekakis J, Ikonomidis I, Siafakas N, Tzortzis S, Trivilou P, Zerva L, Stamboulis E, Kremastinos DT (2009) Cognitive impairment is related to increased arterial stiffness and microvascular damage in patients with never-Treated essential hypertension. Am J Hypertension 22, 525-530.
24. Kearney-Schwartz A, Rossignol P, Bracard S, Felblinger J, Fay R, Boivin JM, Lecompte T, Lacolley P, Benetos A, Zannad F (2009) Vascular structure and function is correlated to cognitive performance and white matter hyperintensities in older hypertensive patients with subjective memory complaints. Stroke 40, 1229-1236.
25. Benetos A, Watfa G, Hanon O, Salvi P, Fantin F, Toulza O, Manckoundia P, Agnoletti D, Labat C, Gautier S, PARTAGE Study I (2012) Pulse wave velocity is associated with 1-year cognitive decline in the elderly older than 80 years: The PARTAGE study. J Am Med Directors Assoc 13, 239-243.
26. Scuteri A, Tesauro M, Appolloni S, Preziosi F, Brancati AM, Volpe M (2007) Arterial stiffness as an independent predictor of longitudinal changes in cognitive function in the older individual. J Hypertension 25, 1035-1040. (Pubitemid 46573123)
27. Henskens LH, Kroon AA, van Oostenbrugge RJ, Gronenschild EH, Fuss-Lejeune MM, Hofman PA, Lodder J, de Leeuw PW (2008) Increased aortic pulse wave velocity is associated with silent cerebral small-Vessel disease in hypertensive patients. Hypertension 52, 1120-1126.
28. Ohmine T, Miwa Y, Yao H, Yuzuriha T, Takashima Y, Uchino A, Takahashi-Yanaga F, Morimoto S, Maehara Y, Sasaguri T (2008) Association between arterial stiffness and cerebral white matter lesions in community-Dwelling elderly subjects. Hypertens Res Clin Exp 31, 75-81. (Pubitemid 351325618)
29. Matsumoto M, Inoue K, Moriki A (2007) Associations of brachial-Ankle pulsewave velocity and carotid atherosclerotic lesions with silent cerebral lesions. Hypertension Res Clin Exp 30, 767-773. (Pubitemid 47578237)
30. Tarumi T, Shah F, Tanaka H, Haley AP (2011) Association between central elastic artery stiffness and cerebral perfusion in deep subcortical gray and white matter. Am J Hypertens 24, 1108-1113.
31. Ikeda M, Hokoishi K, Maki N, Nebu A, Tachibana N, Komori K, Shigenobu K, Fukuhara R, Tanabe H (2001) Increased prevalence of vascular dementia in Japan: A communitybased epidemiological study. Neurology 57, 839-844. (Pubitemid 32845505)
32. Fratiglioni L, Launer LJ, Andersen K, BretelerMM,Copeland JR, Dartigues JF, Lobo A, Martinez-Lage J, Soininen H, Hofman A (2000) Incidence of dementia and major subtypes in Europe: A collaborative study of population-Based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 54, S10-S15. (Pubitemid 30390599)
33. Dhoat S, Ali K, Bulpitt CJ, Rajkumar C (2008) Vascular compliance is reduced in vascular dementia and not in alzheimer's disease. Age Ageing 37, 653-659.
34. Mizushima Y, Oobasawa H, Yoshida S, Irie H, Urata T, Shimoda H (2003) Pulse wave velocity in persons with vascular dementia. J Am Geriatrics Soc 51, 1329-1330. (Pubitemid 37093591)
35. Sparks DL, Scheff SW, Liu H, Landers TM, Coyne CM, Hunsaker JC III (1995) Increased incidence of neurofibrillary tangles (NFT) in non-Demented individuals with hypertension. J Neurol Sci 131, 162-169.
36. Staekenborg SS, van Straaten EC, van der Flier WM, Lane R, Barkhof F, Scheltens P (2008) Small vessel versus large vessel vascular dementia: Risk factors and MRI findings. J Neurol 255, 1644-1651.
37. Sharp SI, Aarsland D, Day S, Sonnesyn H, alzheimer's Society Vascular Dementia Systematic Review G, Ballard C (2011) Hypertension is a potential risk factor for vascular dementia: Systematic review. Int J Geriatr Psych 26, 661-669.
38. Barnes DE, Yaffe K (2011) The projected effect of risk factor reduction on alzheimer's disease prevalence. Lancet Neurol 10, 819-828.
39. Power MC, Weuve J, Gagne JJ, McQueen MB, Viswanathan A, Blacker D (2011) The association between blood pressure and incident alzheimer disease:Asystematic reviewand meta-Analysis. Epidemiology 22, 646-659.
40. Skoog I, Lernfelt B, Landahl S, Palmertz B, Andreasson LA, Nilsson L, Persson G, Oden A, Svanborg A (1996) 15-year longitudinal study of blood pressure and dementia. Lancet 347, 1141-1145. (Pubitemid 126512042)
41. den Heijer T, Launer LJ, Prins ND, van Dijk EJ, Vermeer SE, Hofman A, Koudstaal PJ, Breteler MM (2005) Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe. Neurology 64, 263-267.
42. McGuinness B, Todd S, Passmore P, Bullock R (2009) Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database Syst Rev, CD004034.
43. Duron E, Hanon O (2010) Antihypertensive treatments, cognitive decline, and dementia. J Alzheimers Dis 20, 903-914.
44. Prince MJ, Bird AS, Blizard RA, Mann AH (1996) Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council's trial of hypertension in older adults. BMJ 312, 801-805. (Pubitemid 26099297)
45. Forette F, Seux ML, Staessen JA, Thijs L, Birkenhager WH, Babarskiene MR, Babeanu S, Bossini A, Gil-Extremera B, Girerd X, Laks T, Lilov E, Moisseyev V, Tuomilehto J, Vanhanen H, Webster J, Yodfat Y, Fagard R (1998) Prevention of dementia in randomised double-Blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 352, 1347-1351. (Pubitemid 28510916)
46. De Cesaris R, Ranieri G, Filitti V, Andriani A (1992) Large artery compliance in essential hypertension. Effects of calcium antagonism and beta-Blocking. Am J Hypertens 5, 624-628.
47. Tzourio C, Anderson C, Chapman N, Woodward M, Neal B, MacMahon S, Chalmers J, PROGRESS Collaborative G (2003) Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch Intern Med 163, 1069-1075. (Pubitemid 36548935)
48. Saxby BK, Harrington F,Wesnes KA, McKeith IG, Ford GA (2008) Candesartan and cognitive decline in older patients with hypertension: A substudy of the SCOPE trial. Neurology 70, 1858-1866. (Pubitemid 351653953)
49. Asmar RG, London GM, O'Rourke ME, Safar ME, REASON Project Coordinators and I (2001) Improvement in blood pressure, arterial stiffness and wave reflections with a very-Low-Dose perindopril/indapamide combination in hypertensive patient:Acomparison with atenolol. Hypertension 38, 922-926. (Pubitemid 34258694)
50. Mackenzie IS, McEniery CM, Dhakam Z, Brown MJ, Cockcroft JR, Wilkinson IB (2009) Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension. Hypertension 54, 409-413.
51. Pannier BM, Guerin AP, Marchais SJ, London GM (2001) Different aortic reflection wave responses following long-Term angiotensin-converting enzyme inhibition and beta-Blocker in essential hypertension. Clin Exp Pharm Physiol 28, 1074-1077. (Pubitemid 34053527)
52. Mahmud A, Feely J (2002) Effect of angiotensin ii receptor blockade on arterial stiffness: Beyond blood pressure reduction. Am J Hypertens 15, 1092-1095. (Pubitemid 35397544)
53. Liebetrau M, Burggraf D, Buscher C, Linz W, Hamann GF (2005) Ramipril prevents extracellular matrix accumulation in cerebral microvessels. Neurol Res 27, 477-482. (Pubitemid 41040833)
54. Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV,Williams B, Ford GA (2006) Lifestyle interventions to reduce raised blood pressure: A systematic review of randomized controlled trials. J Hypertens 24, 215-233.
55. Madden KM, Lockhart C, Cuff D, Potter TF, Meneilly GS (2009) Short-Term aerobic exercise reduces arterial stiffness in older adults with type 2 diabetes, hypertension, and hypercholesterolemia. Diabetes Care 32, 1531-1535.
56. Collier SR, Kanaley JA, Carhart R Jr, Frechette V, Tobin MM, Hall AK, Luckenbaugh AN, Fernhall B (2008) Effect of 4 weeks of aerobic or resistance exercise training on arterial stiffness, blood flow and blood pressure in pre- And stage-1 hypertensives. J Human Hypertens 22, 678-686.
57. Sofi F, Valecchi D, Bacci D, Abbate R, Gensini GF, Casini A, Macchi C (2011) Physical activity and risk of cognitive decline: A meta-Analysis of prospective studies. J Intern Med 269, 107-117.
58. O'Rourke MF, Safar ME (2005) Relationship between aortic stiffening and microvascular disease in brain and kidney: Cause and logic of therapy. Hypertension 46, 200-204. (Pubitemid 40946514)
59. Russell RW (1975) How does blood pressure cause stroke. Lancet 306, 1283-1285.
60. Byrom FB (1974) The evolution of acute hypertensive arterial disease. Prog Cardiovasc Dis 17, 31-37.
61. Mitchell GF (2008) Effects of central arterial aging on the structure and function of the peripheral vasculature: Implications for end-organ damage. J Appl Physiol 105, 1652-1660.
62. Liao D, Wong TY, Klein R, Jones D, Hubbard L, Sharrett AR (2004) Relationship between carotid artery stiffness and retinal arteriolar narrowing in healthy middle-Aged persons. Stroke 35, 837-842. (Pubitemid 38419788)
63. MitchellGF,Vita JA, LarsonMG,Parise H,Keyes MJ,Warner E, Vasan RS, Levy D, Benjamin EJ (2005) Cross-Sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: The Framingham Heart Study. Circulation 112, 3722-3728. (Pubitemid 43739512)
64. Roman GC (2004) Brain hypoperfusion: A critical factor in vascular dementia. Neurol Res 26, 454-458. (Pubitemid 38879227)