Large-scale evaluation of the immuno-mycologics lateral flow and enzyme-linked immunoassays for detection of cryptococcal antigen in serum and cerebrospinal fluid

Clinical and Vaccine Immunology

Volumn 20, Issue 1, 2013, Pages 52-55

  Hansen, Jessica ^a   Slechta, E Susan ^a   Gates Hollingsworth, Marcellene A ^b   Neary, Brandon ^c   Barker, Adam P ^d   Bauman, Sean ^c   Kozel, Thomas R ^b   Hanson, Kimberly E ^d  

^a ARUP LABORATORIES   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^c Immuno Mycologics Inc   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOCOCCAL ANTIGEN; EPITOPE; FUNGUS ANTIGEN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN DETECTION; ARTICLE; BACTERIAL STRAIN; BLOOD ANALYSIS; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; CRYPTOCOCCOSIS; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME IMMUNOASSAY; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; INTERMETHOD COMPARISON; LATERAL FLOW ASSAY; LATEX AGGLUTINATION TEST; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEROTYPE;

ANTIGENS, FUNGAL; CEREBROSPINAL FLUID; CLINICAL LABORATORY TECHNIQUES; CRYPTOCOCCOSIS; CRYPTOCOCCUS GATTII; CRYPTOCOCCUS NEOFORMANS; HUMANS; IMMUNOASSAY; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SERUM;

EID: 84872246593     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00536-12     Document Type: Article

References (21)

1. Bloomfield N, Gordon MA, Elmendorf DF, Jr. 1963. Detection of Cryptococcus neoformans antigen in body fluids by latex particle agglutination. Proc. Soc. Exp. Biol. Med. 114:64-67.
2. Babady NE, Bestrom JE, Jespersen DJ, Jones MF, Beito EM, Binnicker MJ, Wengenack NL. 2009. Evaluation of three commercial latex agglutination kits and a commercial enzyme immunoassay for the detection of cryptococcal antigen. Med. Mycol. 47:336-338.
3. Jarvis JN, Percival A, Bauman S, Pelfrey J, Meintjes G, Williams GN, Longley N, Harrison TS, Kozel TR. 2011. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin. Infect. Dis. 53:1019-1023.
4. Tanner DC, Weinstein MP, Fedorciw B, Joho KL, Thorpe JJ, Reller L. 1994. Comparison of commercial kits for detection of cryptococcal antigen. J. Clin. Microbiol. 32:1680-1684. (Pubitemid 24189556)
5. Ikeda R, Nishikawa A, Shinoda T, Fukazawa Y. 1985. Chemical characterization of capsular polysaccharide from Cryptococcus neoformans serotype A-D. Microbiol. Immunol. 29:981-991. (Pubitemid 16257513)
6. Wilson DE, Bennett JE, Bailey JW. 1968. Serologic grouping of Cryptococcus neoformans. Proc. Soc. Exp. Biol. Med. 127:820-823.
7. Byrnes EJ, 3rd, Bartlett KH, Perfect JR, Heitman J. 2011. Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals. Microbes Infect. 13:895-907.
8. Percival A, Thorkildson P, Kozel TR. 2011. Monoclonal antibodies specific for immunorecessive epitopes of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, reduce serotype bias in an immunoassay for cryptococcal antigen. Clin. Vaccine Immunol. 18:1292-1296.
9. Lindsley MD, Mekha N, Baggett HC, Surinthong Y, Autthateinchai R, Sawatwong P, Harris JR, Park BJ, Chiller T, Balajee SA, Poonwan N. 2011. Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis. Clin. Infect. Dis. 53:321-325.
10. Belay T, Cherniak R, Kozel TR, Casadevall A. 1997. Reactivity patterns and epitope specificities of anti-Cryptococcus neoformans monoclonal antibodies by enzyme-linked immunosorbent assay and dot enzyme assay. Infect. Immun. 65:718-728. (Pubitemid 27053245)
11. Brandt S, Thorkildson P, Kozel TR. 2003. Monoclonal antibodies reactive with immunorecessive epitopes of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans. Clin. Diagn. Lab. Immunol. 10:903-909. (Pubitemid 37129507)
12. Eckert TF, Kozel TR. 1987. Production and characterization of monoclonal antibodies specific for Cryptococcus neoformans capsular polysaccharide. Infect. Immun. 55:1895-1899.
13. Gates-Hollingsworth MA, Kozel TR. 2009. Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule. Mol. Microbiol. 74:126-138.
14. Netski D, Kozel TR. 2002. Fc-dependent and Fc-independent opsonization of Cryptococcus neoformans by anticapsular monoclonal antibodies: importance of epitope specificity. Infect. Immun. 70:2812-2819. (Pubitemid 34564136)
15. Spiropulu C, Eppard RA, Otteson E, Kozel TR. 1989. Antigenic variation within serotypes of Cryptococcus neoformans detected by monoclonal antibodies specific for the capsular polysaccharide. Infect. Immun. 57:3240-3242. (Pubitemid 19240102)
16. Clarke S, Gibb R. 2012. Evaluation of the IMMY CrAg lateral flow assay for detection of cryptococcal antigen [abstract]. Aust. Soc. Microbiol. 2012 Annu. Sci. Meet., Brisbane, Australia.
17. Litvintseva AP, Thakur R, Reller LB, Mitchell TG. 2005. Prevalence of clinical isolates of Cryptococcus gattii serotype C among patients with AIDS in sub-Saharan Africa. J. Infect. Dis. 192:888-892. (Pubitemid 41193087)
18. Karstaedt AS, Crewe-Brown HH, Dromer F. 2002. Cryptococcal meningitis caused by Cryptococcus neoformans var. gattii, serotype C, in AIDS patients in Soweto, South Africa. Med. Mycol. 40:7-11. (Pubitemid 34168302)
19. Cogliati M, Chandrashekar N, Esposto MC, Chandramuki A, Petrini B, Viviani MA. 2012. Cryptococcus gattii serotype-C strains isolated in Bangalore, Karnataka, India. Mycoses 55:262-268.
20. Perez C, Dolande M, Moya M, Rosello A, de Capriles CR, Landaeta ME, Mata-Essayag S. 2008. Cryptococcus neoformans, Cryptococcus gattii: serotypes in Venezuela. Mycopathologia 166:149-153.
21. Trilles L, Lazera Mdos S, Wanke B, Oliveira RV, Barbosa GG, Nishikawa MM, Morales BP, Meyer W. 2008. Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil. Mem. Inst. Oswaldo Cruz 103:455-462.