Identification of altered RHD and RHCE alleles: A comparison of manual and automated molecular methods

BeadChip Molecular Immunohematology: Toward Routine Donor and Patient Antigen Profiling by DNA Analysis

Volumn , Issue , 2011, Pages 121-131

  Vege, Sunitha ^a   Westhoff, Connie M ^a  

^a Molecular Blood Group and Platelet Testing Laboratory   (United States)

Author keywords

Blood groups; DNA array; Human erythrocyte antigen; RH; RHCE; RHD

Indexed keywords

EID: 84872235863     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-7512-6_11     Document Type: Chapter

References (19)

1. Wagner FF, Flegel WA (2010) The Rhesus site. http://wwwuni-ulmde/ ~fwagner/RH/RBhtm. Accessed July 2010
2. Blumenfeld OO, Patnaik SK (2004) Allelic genes of blood group antigens: a source of human mutations and cSNPs documented in the Blood Group Antigen Gene Mutation Database. Hum Mutat 23:8-16
3. Schmidt PJ, Morrison EC, Shohl J (1962) The antigenicity of the Rho (Du) blood factor. Blood 20:196-202
4. Wagner T, Kormoczi GF, Buchta C et al. (2005) Anti-D immunization by DEL red blood cells. Transfusion 45:520-526
5. Vege S, Thomas N and Westhoff CM (2010) A screening method to find rare hrB-donors by large-scale screening. Transfusion 50S:150A
6. Noizat-Pirenne F, Lee K, Pennec PY et al. (2002) Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety. Blood 100:4223-4231
7. Daniels GL, Faas BH, Green CA et al. (1998) The VS and V blood group polymorphisms in Africans: a serologic and molecular analysis. Transfusion 38:951-958
8. Vege S, Wolfe J, Marks C et al. (2010) RH alleles associated with donor RhD typing discrepancies. Transfusion 50S:150A
9. Westhoff CM, Vege S, Halter-Hipsky C et al. (2010) DIIIa and DIII type 5 are encoded by the same allele and are associated with altered RHCE*ce alleles: clinical implications. Transfusion 50:1303-1311
10. Shapiro M, Le Roux M, Brink S (1972) Serology and genetics of a new blood factor: hr B. Haematologia (Budap) 6:121-128
11. Moores P (1994) Rh18 and hrS blood groups and antibodies. Vox Sang 66:225-230
12. Hashmi G, Shariff T, Zhang Y et al. (2007) Determination of 24 minor red blood cell antigens for more than 2000 blood donors by high-throughput DNA analysis. Transfusion 47:736-747
13. Avent ND (2007) Large scale blood group genotyping. Transfus Clin Biol 14:10-15
14. Singleton BK, Green CA, Avent ND et al. (2000) The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotype. Blood 95:12-18
15. Chiu RW, Murphy MF, Fidler C et al. (2001) Determination of RhD zygosity: comparison of a double amplification refractory mutation system approach and a multiplex real-time quantitative PCR approach. Clin Chem 47:667-672
16. Vege S, Nickle P, Shirey R et al. (2009) A novel 254G>C (Ala85Gly) change associated with partial Rhe and alloanti-e. Transfusion 49S:15A
17. Rouillac C, Gane P, Cartron J et al. (1996) Molecular basis of the altered antigenic expression of RhD in weak D(Du) and RhC/e in RN phenotypes. Blood 87:4853-4861
18. Westhoff CM, Vege S, Hue-Roye K et al. (2010) Frequency of RHCE*ce(254G>C) in African-American patients and donors. Transfusion 50S:145A
19. Reid ME, Lomas-Francis C (2004) The blood group antigen facts book, 2nd edn. Academic Press, San Diego