-
1
-
-
84872171942
-
-
American cancer society's breast cancer resource. Availiable at
-
American cancer society's breast cancer resource. Availiable at: http://www.cancer.org.
-
-
-
-
2
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin, 2011,61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
-
3
-
-
79551513940
-
Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer
-
Radpour R, Barekati Z, Kohler C, et al. Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer. PLoS One, 2011,6:e16080.
-
(2011)
PLoS One
, vol.6
-
-
Radpour, R.1
Barekati, Z.2
Kohler, C.3
-
4
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet, 2007,8:286-298.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
6
-
-
0037068360
-
DNA methylation and breast carcinogenesis
-
Widschwendter M, Jones PA. DNA methylation and breast carcinogenesis. Oncogene, 2002,21:5462-5482.
-
(2002)
Oncogene
, vol.21
, pp. 5462-5482
-
-
Widschwendter, M.1
Jones, P.A.2
-
7
-
-
36048947234
-
Breast cancer: Origins and evolution
-
Polyak K. Breast cancer: origins and evolution. J Clin Invest, 2007,117:3155-3163.
-
(2007)
J Clin Invest
, vol.117
, pp. 3155-3163
-
-
Polyak, K.1
-
8
-
-
0027059186
-
Hormone resistance, invasiveness, and metastatic potential in breast cancer
-
Clarke R, Thompson EW, Leonessa F, et al. Hormone resistance, invasiveness, and metastatic potential in breast cancer. Breast Cancer Res Treat, 1993,24:227-239.
-
(1993)
Breast Cancer Res Treat
, vol.24
, pp. 227-239
-
-
Clarke, R.1
Thompson, E.W.2
Leonessa, F.3
-
9
-
-
77952798832
-
Epigenetic signatures in breast cancer: Clinical perspective
-
Parrella P. Epigenetic signatures in breast cancer: clinical perspective. Breast Care (Basel), 2010,5:66-73.
-
(2010)
Breast Care (Basel)
, vol.5
, pp. 66-73
-
-
Parrella, P.1
-
10
-
-
67449127092
-
CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis
-
Wang Y, Li J, Cui Y, et al. CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Res, 2009, 69:5194-5201.
-
(2009)
Cancer Res
, vol.69
, pp. 5194-5201
-
-
Wang, Y.1
Li, J.2
Cui, Y.3
-
11
-
-
52049115449
-
OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation
-
Cui Y, Ying Y, van Hasselt A, et al. OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation. PLoS One, 2008,3:e2990.
-
(2008)
PLoS One
, vol.3
-
-
Cui, Y.1
Ying, Y.2
van Hasselt, A.3
-
12
-
-
33745634864
-
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer
-
Ai L, Tao Q, Zhong S, et al. Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis, 2006,27: 1341-1348.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1341-1348
-
-
Ai, L.1
Tao, Q.2
Zhong, S.3
-
13
-
-
77957143981
-
PLCD1 is a functional tumor suppressor inducing G (2)/M arrest and frequently methylated in breast cancer
-
Xiang T, Li L, Fan Y, et al. PLCD1 is a functional tumor suppressor inducing G (2)/M arrest and frequently methylated in breast cancer. Cancer Biol Ther, 2010,10:520-527.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 520-527
-
-
Xiang, T.1
Li, L.2
Fan, Y.3
-
14
-
-
35348891510
-
CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines
-
Shao L, Cui Y, Li H, et al. CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines. Clin Cancer Res, 2007,13:5756-5762.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5756-5762
-
-
Shao, L.1
Cui, Y.2
Li, H.3
-
15
-
-
79955466717
-
A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors
-
Low JS, Tao Q, Ng KM, et al. A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors. Oncogene, 2011,30:1923-1935.
-
(2011)
Oncogene
, vol.30
, pp. 1923-1935
-
-
Low, J.S.1
Tao, Q.2
Ng, K.M.3
-
16
-
-
51349083104
-
Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas
-
Lee KY, Geng H, Ng KM, et al. Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. Oncogene, 2008, 27:5267-5276.
-
(2008)
Oncogene
, vol.27
, pp. 5267-5276
-
-
Lee, K.Y.1
Geng, H.2
Ng, K.M.3
-
17
-
-
0035865285
-
Effectiveness of breast cancer surveillance in BRCA1/2 gene mutation carriers and women with high familial risk
-
Brekelmans CT, Seynaeve C, Bartels CC, et al. Effectiveness of breast cancer surveillance in BRCA1/2 gene mutation carriers and women with high familial risk. J Clin Oncol, 2001,19:924-930.
-
(2001)
J Clin Oncol
, vol.19
, pp. 924-930
-
-
Brekelmans, C.T.1
Seynaeve, C.2
Bartels, C.C.3
-
18
-
-
72449138778
-
Methylation of cystatin M promoter is associated with unfavorable prognosis in operable breast cancer
-
Kioulafa M, Balkouranidou I, Sotiropoulou G, et al. Methylation of cystatin M promoter is associated with unfavorable prognosis in operable breast cancer. Int J Cancer, 2009,125: 2887-2892.
-
(2009)
Int J Cancer
, vol.125
, pp. 2887-2892
-
-
Kioulafa, M.1
Balkouranidou, I.2
Sotiropoulou, G.3
-
19
-
-
39449107433
-
Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer
-
Potapova A, Hoffman AM, Godwin AK, et al. Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer. Cancer Res, 2008,68: 998-1002.
-
(2008)
Cancer Res
, vol.68
, pp. 998-1002
-
-
Potapova, A.1
Hoffman, A.M.2
Godwin, A.K.3
-
20
-
-
68949125077
-
Clinical significance of epigenetic inactivation of hMLH1 and BRCA1 in Tunisian patients with invasive breast carcinoma
-
Karray-Chouayekh S, Trifa F, Khabir A, et al. Clinical significance of epigenetic inactivation of hMLH1 and BRCA1 in Tunisian patients with invasive breast carcinoma. J Biomed Biotechnol, 2009,2009:369129.
-
(2009)
J Biomed Biotechnol
, vol.2009
, pp. 369129
-
-
Karray-Chouayekh, S.1
Trifa, F.2
Khabir, A.3
-
21
-
-
68349139365
-
Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
-
Veeck J, Wild PJ, Fuchs T, et al. Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer. BMC Cancer, 2009,9:217.
-
(2009)
BMC Cancer
, vol.9
, pp. 217
-
-
Veeck, J.1
Wild, P.J.2
Fuchs, T.3
-
22
-
-
57149145660
-
Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression
-
Tian K, Wang Y, Huang Y, et al. Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression. BMC Cancer, 2008,8:327.
-
(2008)
BMC Cancer
, vol.8
, pp. 327
-
-
Tian, K.1
Wang, Y.2
Huang, Y.3
-
23
-
-
78549283515
-
Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer
-
Ko E, Park SE, Cho EY, et al. Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer. Breast Cancer Res, 2010,12:R100.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Ko, E.1
Park, S.E.2
Cho, E.Y.3
-
25
-
-
18844470774
-
Detection of breast cancer cells in ductal lavage fluid by methylation-s pecific PCR
-
Evron E, Dooley WC, Umbricht CB, et al. Detection of breast cancer cells in ductal lavage fluid by methylation-s pecific PCR. Lancet, 2001,357:1335-1336.
-
(2001)
Lancet
, vol.357
, pp. 1335-1336
-
-
Evron, E.1
Dooley, W.C.2
Umbricht, C.B.3
-
26
-
-
3042825295
-
Quantitative multiplex methylation-s pecific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer
-
Fackler MJ, McVeigh M, Mehrotra J, et al. Quantitative multiplex methylation-s pecific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer. Cancer Res, 2004,64:4442-4452.
-
(2004)
Cancer Res
, vol.64
, pp. 4442-4452
-
-
Fackler, M.J.1
McVeigh, M.2
Mehrotra, J.3
-
27
-
-
33745184403
-
Quantitative multiplex methylation-s pecific PCR analysis doubles detection of tumor cells in breast ductal fluid
-
Fackler MJ, Malone K, Zhang Z, et al. Quantitative multiplex methylation-s pecific PCR analysis doubles detection of tumor cells in breast ductal fluid. Clin Cancer Res, 2006,12:3306-3310.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3306-3310
-
-
Fackler, M.J.1
Malone, K.2
Zhang, Z.3
-
28
-
-
33745026527
-
Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis
-
Veeck J, Niederacher D, An H, et al. Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis. Oncogene, 2006,25:3479-3488.
-
(2006)
Oncogene
, vol.25
, pp. 3479-3488
-
-
Veeck, J.1
Niederacher, D.2
An, H.3
-
29
-
-
33750364352
-
Association of GSTP1 CpG islands hypermethylation with poor prognosis in human breast cancers
-
Arai T, Miyoshi Y, Kim SJ, et al. Association of GSTP1 CpG islands hypermethylation with poor prognosis in human breast cancers. Breast Cancer Res Treat, 2006,100:169-176.
-
(2006)
Breast Cancer Res Treat
, vol.100
, pp. 169-176
-
-
Arai, T.1
Miyoshi, Y.2
Kim, S.J.3
-
30
-
-
0034051419
-
CpG island arrays: An application toward deciphering epigenetic signatures of breast cancer
-
Yan PS, Perry MR, Laux DE, et al. CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer. Clin Cancer Res, 2000,6:1432-1438.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1432-1438
-
-
Yan, P.S.1
Perry, M.R.2
Laux, D.E.3
-
31
-
-
77958540564
-
Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
-
Holm K, Hegardt C, Staaf J, et al. Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns. Breast Cancer Res, 2010,12:R36.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Holm, K.1
Hegardt, C.2
Staaf, J.3
-
32
-
-
33846252747
-
Circulating methylated DNA: A new generation of tumor markers
-
Widschwendter M, Menon U. Circulating methylated DNA: a new generation of tumor markers. Clin Cancer Res, 2006,12: 7205-7208.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7205-7208
-
-
Widschwendter, M.1
Menon, U.2
-
33
-
-
18544406053
-
DNA methylation in serum of breast cancer patients: An independent prognostic marker
-
Muller HM, Widschwendter A, Fiegl H, et al. DNA methylation in serum of breast cancer patients: an independent prognostic marker. Cancer Res, 2003,63:7641-7645.
-
(2003)
Cancer Res
, vol.63
, pp. 7641-7645
-
-
Muller, H.M.1
Widschwendter, A.2
Fiegl, H.3
-
34
-
-
4644297522
-
Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients
-
Dulaimi E, Hillinck J, Ibanez de Caceres I, et al. Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients. Clin Cancer Res, 2004,10:6189-6193.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6189-6193
-
-
Dulaimi, E.1
Hillinck, J.2
de Caceres, I.I.3
-
35
-
-
56149088621
-
Quantitative detection of methylated ESR1 and 14-3-3-si gma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy
-
Martinez-Galan J, Torres B, Del Moral R, et al. Quantitative detection of methylated ESR1 and 14-3-3-si gma gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy. Cancer Biol Ther, 2008,7:958-965.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 958-965
-
-
Martinez-Galan, J.1
Torres, B.2
Del Moral, R.3
-
36
-
-
67349231169
-
Optimizing the yield and utility of circulating cell-free DNA from plasma and serum
-
Xue X, Teare MD, Holen I, et al. Optimizing the yield and utility of circulating cell-free DNA from plasma and serum. Clin Chim Acta, 2009,404:100-104.
-
(2009)
Clin Chim Acta
, vol.404
, pp. 100-104
-
-
Xue, X.1
Teare, M.D.2
Holen, I.3
-
38
-
-
79952122331
-
Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing
-
Sun Z, Asmann YW, Kalari KR, et al. Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing. PLoS One, 2011,6:e17490.
-
(2011)
PLoS One
, vol.6
-
-
Sun, Z.1
Asmann, Y.W.2
Kalari, K.R.3
-
39
-
-
33750596313
-
Epigenetic cancer therapy makes headway
-
Mack GS. Epigenetic cancer therapy makes headway. J Natl Cancer Inst, 2006,98:1443-1444.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1443-1444
-
-
Mack, G.S.1
-
40
-
-
34548414620
-
Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors
-
Appleton K, Mackay HJ, Judson I, et al. Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. J Clin Oncol, 2007,25:4603-4609.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4603-4609
-
-
Appleton, K.1
Mackay, H.J.2
Judson, I.3
-
41
-
-
0032522949
-
Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: A phase II study by the Cancer and Leukemia Group B
-
Samuels BL, Herndon JE, 2nd, Harmon DC, et al. Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. Cancer, 1998,82:1578-1584.
-
(1998)
Cancer
, vol.82
, pp. 1578-1584
-
-
Samuels, B.L.1
Herndon II, J.E.2
Harmon, D.C.3
-
42
-
-
33744484523
-
Epstein-Barr virus (EBV) and its associated human cancers-genetics, epigenetics, pathobiology and novel therapeutics
-
Tao Q, Young LS, Woodman CB, et al. Epstein-Barr virus (EBV) and its associated human cancers-genetics, epigenetics, pathobiology and novel therapeutics. Front Biosci, 2006,11:2672-2713.
-
(2006)
Front Biosci
, vol.11
, pp. 2672-2713
-
-
Tao, Q.1
Young, L.S.2
Woodman, C.B.3
-
44
-
-
77950867869
-
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells
-
Billam M, Sobolewski MD, Davidson NE. Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. Breast Cancer Res Treat, 2010,120:581-592.
-
(2010)
Breast Cancer Res Treat
, vol.120
, pp. 581-592
-
-
Billam, M.1
Sobolewski, M.D.2
Davidson, N.E.3
-
45
-
-
1542787625
-
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines
-
Yan L, Nass SJ, Smith D, et al. Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines. Cancer Biol Ther, 2003,2:552-556.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 552-556
-
-
Yan, L.1
Nass, S.J.2
Smith, D.3
-
46
-
-
65649152375
-
Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors
-
Plummer R, Vidal L, Griffin M, et al. Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors. Clin Cancer Res, 2009,15: 3177-3183.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3177-3183
-
-
Plummer, R.1
Vidal, L.2
Griffin, M.3
-
47
-
-
42249104213
-
A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia
-
Klisovic RB, Stock W, Cataland S, et al. A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia. Clin Cancer Res, 2008,14:2444-2449.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2444-2449
-
-
Klisovic, R.B.1
Stock, W.2
Cataland, S.3
-
48
-
-
22244435605
-
Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases
-
Brueckner B, Garcia Boy R, Siedlecki P, et al. Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases. Cancer Res, 2005,65:6305-6311.
-
(2005)
Cancer Res
, vol.65
, pp. 6305-6311
-
-
Brueckner, B.1
Garcia, B.R.2
Siedlecki, P.3
-
49
-
-
50249091120
-
Chemical regulation of epigenetic modifications: Opportunities for new cancer therapy
-
Zheng YG, Wu J, Chen Z, et al. Chemical regulation of epigenetic modifications: opportunities for new cancer therapy. Med Res Rev, 2008,28:645-687.
-
(2008)
Med Res Rev
, vol.28
, pp. 645-687
-
-
Zheng, Y.G.1
Wu, J.2
Chen, Z.3
-
50
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet, 1999,21: 103-107.
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
-
51
-
-
0035477320
-
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells
-
Yang X, Phillips DL, Ferguson AT, et al. Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. Cancer Res, 2001,61: 7025-7029.
-
(2001)
Cancer Res
, vol.61
, pp. 7025-7029
-
-
Yang, X.1
Phillips, D.L.2
Ferguson, A.T.3
-
52
-
-
1642339046
-
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen
-
Jang ER, Lim SJ, Lee ES, et al. The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen. Oncogene, 2004,23: 1724-1736.
-
(2004)
Oncogene
, vol.23
, pp. 1724-1736
-
-
Jang, E.R.1
Lim, S.J.2
Lee, E.S.3
-
53
-
-
24344473755
-
Activity of suberoylanilide hydroxamic acid against human breast cancer cells with amplification of her-2
-
Bali P, Pranpat M, Swaby R, et al. Activity of suberoylanilide hydroxamic acid against human breast cancer cells with amplification of her-2. Clin Cancer Res, 2005, 11: 6382-6389.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6382-6389
-
-
Bali, P.1
Pranpat, M.2
Swaby, R.3
-
54
-
-
1642490813
-
Histone deacetylase inhibitor LAQ824 down-re gulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B
-
Fuino L, Bali P, Wittmann S, et al. Histone deacetylase inhibitor LAQ824 down-re gulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B. Mol Cancer Ther, 2003,2:971-984.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 971-984
-
-
Fuino, L.1
Bali, P.2
Wittmann, S.3
-
55
-
-
1542299085
-
Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines
-
Hurtubise A, Momparler RL. Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines. Anticancer Drugs, 2004,15:161-167.
-
(2004)
Anticancer Drugs
, vol.15
, pp. 161-167
-
-
Hurtubise, A.1
Momparler, R.L.2
-
56
-
-
77957784810
-
Synergistic epigenetic reactivation of estrogen receptor-alpha (ERalpha) by combined green tea polyphenol and histone deacetylase inhibitor in ERalpha-negative breast cancer cells
-
Li Y, Yuan YY, Meeran SM, et al. Synergistic epigenetic reactivation of estrogen receptor-alpha (ERalpha) by combined green tea polyphenol and histone deacetylase inhibitor in ERalpha-negative breast cancer cells. Mol Cancer, 2010,9:274.
-
(2010)
Mol Cancer
, vol.9
, pp. 274
-
-
Li, Y.1
Yuan, Y.Y.2
Meeran, S.M.3
-
57
-
-
77955352742
-
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
-
Meeran SM, Patel SN, Tollefsbol TO. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One, 2010,5:e11457.
-
(2010)
PLoS One
, vol.5
-
-
Meeran, S.M.1
Patel, S.N.2
Tollefsbol, T.O.3
-
58
-
-
74849127193
-
Epigenetic therapy: Histone acetylation, DNA methylation and anti-cancer drug discovery
-
Ganesan A, Nolan L, Crabb SJ, et al. Epigenetic therapy: histone acetylation, DNA methylation and anti-cancer drug discovery. Curr Cancer Drug Targets, 2009,9:963-981.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 963-981
-
-
Ganesan, A.1
Nolan, L.2
Crabb, S.J.3
-
59
-
-
34249937594
-
Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: A clinical and translational study
-
Munster P, Marchion D, Bicaku E, et al. Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study. J Clin Oncol, 2007,25:1979-1985.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1979-1985
-
-
Munster, P.1
Marchion, D.2
Bicaku, E.3
-
60
-
-
11244335534
-
The ATM gene is a target for epigenetic silencing in locally advanced breast cancer
-
Vo QN, Kim WJ, Cvitanovic L, et al. The ATM gene is a target for epigenetic silencing in locally advanced breast cancer. Oncogene, 2004,23:9432-9437.
-
(2004)
Oncogene
, vol.23
, pp. 9432-9437
-
-
Vo, Q.N.1
Kim, W.J.2
Cvitanovic, L.3
-
61
-
-
8444224421
-
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: Changes in chromatin structure induced by treatment with 5-A za-cytidine
-
David GL, Yegnasubramanian S, Kumar A, et al. MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-A za-cytidine. Cancer Biol Ther, 2004,3:540-548.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 540-548
-
-
David, G.L.1
Yegnasubramanian, S.2
Kumar, A.3
-
62
-
-
77952248685
-
DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
-
Dejeux E, Ronneberg JA, Solvang H, et al. DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response. Mol Cancer, 2010,9:68.
-
(2010)
Mol Cancer
, vol.9
, pp. 68
-
-
Dejeux, E.1
Ronneberg, J.A.2
Solvang, H.3
-
63
-
-
0034772312
-
Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas
-
Virmani AK, Rathi A, Sathyanarayana UG, et al. Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas. Clin Cancer Res, 2001,7:1998-2004.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1998-2004
-
-
Virmani, A.K.1
Rathi, A.2
Sathyanarayana, U.G.3
-
64
-
-
0035816342
-
Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers
-
Jin Z, Tamura G, Tsuchiya T, et al. Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers. Br J Cancer, 2001,85:69-73.
-
(2001)
Br J Cancer
, vol.85
, pp. 69-73
-
-
Jin, Z.1
Tamura, G.2
Tsuchiya, T.3
-
65
-
-
77952272127
-
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
-
Li Z, Chen B, Wu Y, et al. Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. BMC Cancer, 2010,10:98.
-
(2010)
BMC Cancer
, vol.10
, pp. 98
-
-
Li, Z.1
Chen, B.2
Wu, Y.3
-
66
-
-
34249812700
-
Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer
-
Kuznetsova EB, Kekeeva TV, Larin SS, et al. Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer. J Carcinog, 2007,6:9.
-
(2007)
J Carcinog
, vol.6
, pp. 9
-
-
Kuznetsova, E.B.1
Kekeeva, T.V.2
Larin, S.S.3
-
67
-
-
49249136904
-
Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
-
Tapia T, Smalley SV, Kohen P, et al. Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors. Epigenetics, 2008,3:157-163.
-
(2008)
Epigenetics
, vol.3
, pp. 157-163
-
-
Tapia, T.1
Smalley, S.V.2
Kohen, P.3
-
68
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst, 2000,92:564-569.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
69
-
-
77951551352
-
Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression
-
Si J, Yu X, Zhang Y, et al. Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression. Mol Cancer, 2010,9:92.
-
(2010)
Mol Cancer
, vol.9
, pp. 92
-
-
Si, J.1
Yu, X.2
Zhang, Y.3
-
70
-
-
64549090667
-
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells
-
Yang X, Karuturi RK, Sun F, et al. CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS One, 2009, 4: e5011.
-
(2009)
PLoS One
, vol.4
-
-
Yang, X.1
Karuturi, R.K.2
Sun, F.3
-
71
-
-
34548249665
-
Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions
-
Rivenbark AG, Livasy CA, Boyd CE, et al. Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions. Exp Mol Pathol, 2007,83:188-197.
-
(2007)
Exp Mol Pathol
, vol.83
, pp. 188-197
-
-
Rivenbark, A.G.1
Livasy, C.A.2
Boyd, C.E.3
-
72
-
-
33748041100
-
Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression
-
Ai L, Kim WJ, Kim TY, et al. Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. Cancer Res, 2006,66:7899-7909.
-
(2006)
Cancer Res
, vol.66
, pp. 7899-7909
-
-
Ai, L.1
Kim, W.J.2
Kim, T.Y.3
-
73
-
-
23844489449
-
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation
-
Paredes J, Albergaria A, Oliveira JT, et al. P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. Clin Cancer Res, 2005,11:5869-5877.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5869-5877
-
-
Paredes, J.1
Albergaria, A.2
Oliveira, J.T.3
-
74
-
-
0035360824
-
Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas
-
Toyooka KO, Toyooka S, Virmani AK, et al. Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas. Cancer Res, 2001, 61:4556-4560.
-
(2001)
Cancer Res
, vol.61
, pp. 4556-4560
-
-
Toyooka, K.O.1
Toyooka, S.2
Virmani, A.K.3
-
75
-
-
78049371701
-
Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis
-
Loo WT, Jin L, Cheung MN, et al. Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis. J Transl Med, 2010,8:110.
-
(2010)
J Transl Med
, vol.8
, pp. 110
-
-
Loo, W.T.1
Jin, L.2
Cheung, M.N.3
-
76
-
-
77952804730
-
CDO1 promoter methylation is a biomarker for outcome prediction of anthracycline treated, estrogen receptor-positive, lymph node-positive breast cancer patients
-
Dietrich D, Krispin M, Dietrich J, et al. CDO1 promoter methylation is a biomarker for outcome prediction of anthracycline treated, estrogen receptor-positive, lymph node-positive breast cancer patients. BMC Cancer, 2010,10:247.
-
(2010)
BMC Cancer
, vol.10
, pp. 247
-
-
Dietrich, D.1
Krispin, M.2
Dietrich, J.3
-
77
-
-
77950536708
-
Identification of 5 novel genes methylated in breast and other epithelial cancers
-
Hill VK, Hesson LB, Dansranjavin T, et al. Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer, 2010,9:51.
-
(2010)
Mol Cancer
, vol.9
, pp. 51
-
-
Hill, V.K.1
Hesson, L.B.2
Dansranjavin, T.3
-
78
-
-
0035866809
-
Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation
-
Evron E, Umbricht CB, Korz D, et al. Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation. Cancer Res, 2001, 61: 2782-2787.
-
(2001)
Cancer Res
, vol.61
, pp. 2782-2787
-
-
Evron, E.1
Umbricht, C.B.2
Korz, D.3
-
79
-
-
77949463477
-
Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
-
Van der Auwera I, Bovie C, Svensson C, et al. Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients. BMC Cancer, 2010,10:97.
-
(2010)
BMC Cancer
, vol.10
, pp. 97
-
-
van der, A.I.1
Bovie, C.2
Svensson, C.3
-
80
-
-
40849116461
-
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
-
Suzuki H, Toyota M, Carraway H, et al. Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer, 2008,98:1147-1156.
-
(2008)
Br J Cancer
, vol.98
, pp. 1147-1156
-
-
Suzuki, H.1
Toyota, M.2
Carraway, H.3
-
81
-
-
59449089531
-
Wnt signalling in human breast cancer: Expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours
-
Veeck J, Bektas N, Hartmann A, et al. Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours. Breast Cancer Res, 2008,10:R82.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Veeck, J.1
Bektas, N.2
Hartmann, A.3
-
82
-
-
33846941189
-
The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation
-
Seng TJ, Low JS, Li H, et al. The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. Oncogene, 2007,26:934-944.
-
(2007)
Oncogene
, vol.26
, pp. 934-944
-
-
Seng, T.J.1
Low, J.S.2
Li, H.3
-
83
-
-
0034662645
-
Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer
-
Nass SJ, Herman JG, Gabrielson E, et al. Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer. Cancer Res, 2000,60:4346-4348.
-
(2000)
Cancer Res
, vol.60
, pp. 4346-4348
-
-
Nass, S.J.1
Herman, J.G.2
Gabrielson, E.3
-
84
-
-
0028318783
-
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
-
Ottaviano YL, Issa JP, Parl FF, et al. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res, 1994,54:2552-2555.
-
(1994)
Cancer Res
, vol.54
, pp. 2552-2555
-
-
Ottaviano, Y.L.1
Issa, J.P.2
Parl, F.F.3
-
85
-
-
0032526094
-
Mapping of ER gene CpG island methylation-s pecific polymerase chain reaction
-
Lapidus RG, Nass SJ, Butash KA, et al. Mapping of ER gene CpG island methylation-s pecific polymerase chain reaction. Cancer Res, 1998,58:2515-2519.
-
(1998)
Cancer Res
, vol.58
, pp. 2515-2519
-
-
Lapidus, R.G.1
Nass, S.J.2
Butash, K.A.3
-
86
-
-
0028849277
-
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas
-
Graff JR, Herman JG, Lapidus RG, et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res, 1995,55:5195-5199.
-
(1995)
Cancer Res
, vol.55
, pp. 5195-5199
-
-
Graff, J.R.1
Herman, J.G.2
Lapidus, R.G.3
-
87
-
-
74049135484
-
Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer
-
Wiesmann F, Veeck J, Galm O, et al. Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer. Breast Cancer Res, 2009,11:R34.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Wiesmann, F.1
Veeck, J.2
Galm, O.3
-
88
-
-
71249098177
-
Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer
-
Fu DY, Wang ZM, Wang BL, et al. Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. Hum Pathol, 2010,41:48-58.
-
(2010)
Hum Pathol
, vol.41
, pp. 48-58
-
-
Fu, D.Y.1
Wang, Z.M.2
Wang, B.L.3
-
89
-
-
22244479985
-
Identification of 20 genes aberrantly methylated in human breast cancers
-
Miyamoto K, Fukutomi T, Akashi-Tanaka S, et al. Identification of 20 genes aberrantly methylated in human breast cancers. Int J Cancer, 2005,116:407-414.
-
(2005)
Int J Cancer
, vol.116
, pp. 407-414
-
-
Miyamoto, K.1
Fukutomi, T.2
Akashi-Tanaka, S.3
-
90
-
-
78649494384
-
Inactivation of FBXW7/hCDC4-beta expression by promoter hypermethy-lation is associated with favorable prognosis in primary breast cancer
-
Akhoondi S, Lindstrom L, Widschwendter M, et al. Inactivation of FBXW7/hCDC4-beta expression by promoter hypermethy-lation is associated with favorable prognosis in primary breast cancer. Breast Cancer Res, 2010,12:R105.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Akhoondi, S.1
Lindstrom, L.2
Widschwendter, M.3
-
91
-
-
17844395749
-
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer
-
Wang W, Huper G, Guo Y, et al. Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene, 2005,24:2705-2714.
-
(2005)
Oncogene
, vol.24
, pp. 2705-2714
-
-
Wang, W.1
Huper, G.2
Guo, Y.3
-
92
-
-
0032532092
-
Inactivation of glutathione S-transferase P1 gene by promoter hyper-methylation in human neoplasia
-
Esteller M, Corn PG, Urena JM, et al. Inactivation of glutathione S-transferase P1 gene by promoter hyper-methylation in human neoplasia. Cancer Res, 1998,58:4515-4518.
-
(1998)
Cancer Res
, vol.58
, pp. 4515-4518
-
-
Esteller, M.1
Corn, P.G.2
Urena, J.M.3
-
93
-
-
77956945027
-
Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells
-
Das PM, Thor AD, Edgerton SM, et al. Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells. Oncogene, 2010,29:5214-5219.
-
(2010)
Oncogene
, vol.29
, pp. 5214-5219
-
-
Das, P.M.1
Thor, A.D.2
Edgerton, S.M.3
-
94
-
-
0029014425
-
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
-
Wales MM, Biel MA, El Deiry W, et al. p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med, 1995,1:570-577.
-
(1995)
Nat Med
, vol.1
, pp. 570-577
-
-
Wales, M.M.1
Biel, M.A.2
El, D.W.3
-
95
-
-
0242677806
-
DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma
-
Fackler MJ, McVeigh M, Evron E, et al. DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Int J Cancer, 2003,107:970-975.
-
(2003)
Int J Cancer
, vol.107
, pp. 970-975
-
-
Fackler, M.J.1
McVeigh, M.2
Evron, E.3
-
96
-
-
0035859831
-
HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells
-
Krop IE, Sgroi D, Porter DA, et al. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proc Natl Acad Sci U S A, 2001, 98:9796-9801.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9796-9801
-
-
Krop, I.E.1
Sgroi, D.2
Porter, D.A.3
-
97
-
-
0034702232
-
Compromised HOXA5 function can limit p53 expression in human breast tumours
-
Raman V, Martensen SA, Reisman D, et al. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature, 2000,405:974-978.
-
(2000)
Nature
, vol.405
, pp. 974-978
-
-
Raman, V.1
Martensen, S.A.2
Reisman, D.3
-
98
-
-
0029976873
-
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
-
Issa JP, Vertino PM, Boehm CD, et al. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proc Natl Acad Sci U S A, 1996,93:11757-11762.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 11757-11762
-
-
Issa, J.P.1
Vertino, P.M.2
Boehm, C.D.3
-
99
-
-
68949088285
-
Deregulation of 2 potassium channels in pancreas adenocarcinomas: Implication of KV1.3 gene promoter methylation
-
Brevet M, Fucks D, Chatelain D, et al. Deregulation of 2 potassium channels in pancreas adenocarcinomas: implication of KV1.3 gene promoter methylation. Pancreas, 2009,38:649-654.
-
(2009)
Pancreas
, vol.38
, pp. 649-654
-
-
Brevet, M.1
Fucks, D.2
Chatelain, D.3
-
100
-
-
66149118937
-
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer
-
Shah R, Smith P, Purdie C, et al. The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. Br J Cancer, 2009,100:1687-1696.
-
(2009)
Br J Cancer
, vol.100
, pp. 1687-1696
-
-
Shah, R.1
Smith, P.2
Purdie, C.3
-
101
-
-
0029934262
-
Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors
-
Lapidus RG, Ferguson AT, Ottaviano YL, et al. Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors. Clin Cancer Res, 1996,2: 805-810.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 805-810
-
-
Lapidus, R.G.1
Ferguson, A.T.2
Ottaviano, Y.L.3
-
102
-
-
22344439580
-
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells
-
Keen JC, Garrett-Mayer E, Pettit C, et al. Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. Cancer Biol Ther, 2004,3:1304-1312.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 1304-1312
-
-
Keen, J.C.1
Garrett-Mayer, E.2
Pettit, C.3
-
103
-
-
0028845142
-
Inactivation of the CDKN2/ p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/ p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res, 1995,55:4525-4530.
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
-
104
-
-
54949134514
-
Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer
-
Suijkerbuijk KP, Fackler MJ, Sukumar S, et al. Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer. Ann Oncol, 2008,19:1870-1874.
-
(2008)
Ann Oncol
, vol.19
, pp. 1870-1874
-
-
Suijkerbuijk, K.P.1
Fackler, M.J.2
Sukumar, S.3
-
105
-
-
18244388241
-
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
-
Esteller M, Fraga MF, Guo M, et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet, 2001,10:3001-3007.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 3001-3007
-
-
Esteller, M.1
Fraga, M.F.2
Guo, M.3
-
106
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller M, Corn PG, Baylin SB, et al. A gene hypermethylation profile of human cancer. Cancer Res, 2001,61:3225-3229.
-
(2001)
Cancer Res
, vol.61
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
-
107
-
-
0036170908
-
Quantitative assessment of promoter hypermethylation during breast cancer development
-
Lehmann U, Langer F, Feist H, et al. Quantitative assessment of promoter hypermethylation during breast cancer development. Am J Pathol, 2002,160:605-612.
-
(2002)
Am J Pathol
, vol.160
, pp. 605-612
-
-
Lehmann, U.1
Langer, F.2
Feist, H.3
-
108
-
-
20044394366
-
p16 (INK4a) promoter methylation and protein expression in breast fibroadenoma and carcinoma
-
Di Vinci A, Perdelli L, Banelli B, et al. p16 (INK4a) promoter methylation and protein expression in breast fibroadenoma and carcinoma. Int J Cancer, 2005,114:414-421.
-
(2005)
Int J Cancer
, vol.114
, pp. 414-421
-
-
Di Vinci, A.1
Perdelli, L.2
Banelli, B.3
-
109
-
-
4143138570
-
Promoter methylation of the PTEN gene is a common molecular change in breast cancer
-
Garcia JM, Silva J, Pena C, et al. Promoter methylation of the PTEN gene is a common molecular change in breast cancer. Genes Chromosomes Cancer, 2004,41:117-124.
-
(2004)
Genes Chromosomes Cancer
, vol.41
, pp. 117-124
-
-
Garcia, J.M.1
Silva, J.2
Pena, C.3
-
110
-
-
0034679027
-
Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer
-
Widschwendter M, Berger J, Hermann M, et al. Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer. J Natl Cancer Inst, 2000,92:826-832.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 826-832
-
-
Widschwendter, M.1
Berger, J.2
Hermann, M.3
-
111
-
-
0036558155
-
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer
-
Sirchia SM, Ren M, Pili R, et al. Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. Cancer Res, 2002,62:2455-2461.
-
(2002)
Cancer Res
, vol.62
, pp. 2455-2461
-
-
Sirchia, S.M.1
Ren, M.2
Pili, R.3
-
112
-
-
0035890771
-
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
-
Du Y, Carling T, Fang W, et al. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res, 2001,61:8094-8099.
-
(2001)
Cancer Res
, vol.61
, pp. 8094-8099
-
-
Du, Y.1
Carling, T.2
Fang, W.3
-
113
-
-
0035300429
-
Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers
-
Dammann R, Yang G, Pfeifer GP. Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res, 2001,61:3105-3109.
-
(2001)
Cancer Res
, vol.61
, pp. 3105-3109
-
-
Dammann, R.1
Yang, G.2
Pfeifer, G.P.3
-
114
-
-
17844362997
-
High frequency of promoter hypermethylation of RASSF1A in tumorous and non-tu mourous tissue of breast cancer
-
Yeo W, Wong WL, Wong N, et al. High frequency of promoter hypermethylation of RASSF1A in tumorous and non-tu mourous tissue of breast cancer. Pathology, 2005,37:125-130.
-
(2005)
Pathology
, vol.37
, pp. 125-130
-
-
Yeo, W.1
Wong, W.L.2
Wong, N.3
-
115
-
-
18144411303
-
Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
-
Agathanggelou A, Cooper WN, Latif F. Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. Cancer Res, 2005,65:3497-3508.
-
(2005)
Cancer Res
, vol.65
, pp. 3497-3508
-
-
Agathanggelou, A.1
Cooper, W.N.2
Latif, F.3
-
116
-
-
68549133226
-
Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers
-
Yang ZQ, Liu G, Bollig-Fischer A, et al. Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers. Int J Cancer, 2009,125:1613-1621.
-
(2009)
Int J Cancer
, vol.125
, pp. 1613-1621
-
-
Yang, Z.Q.1
Liu, G.2
Bollig-Fischer, A.3
-
117
-
-
38449112647
-
Epigenetic inactivation of the WNT antagonist SFRP1 in breast cancer
-
Dahl E, Veeck J, An H, et al. Epigenetic inactivation of the WNT antagonist SFRP1 in breast cancer. Verh Dtsch Ges Pathol, 2005,89:169-177.
-
(2005)
Verh Dtsch Ges Pathol
, vol.89
, pp. 169-177
-
-
Dahl, E.1
Veeck, J.2
An, H.3
-
118
-
-
47249164378
-
Epigenetic inactivation of the secreted frizzled-re lated protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis
-
Veeck J, Geisler C, Noetzel E, et al. Epigenetic inactivation of the secreted frizzled-re lated protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis. Carcinogenesis, 2008,29:991-998.
-
(2008)
Carcinogenesis
, vol.29
, pp. 991-998
-
-
Veeck, J.1
Geisler, C.2
Noetzel, E.3
-
119
-
-
74849121190
-
Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer
-
Fu DY, Wang ZM, Li C, et al. Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer. Breast Cancer Res Treat, 2010,119: 601-612.
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 601-612
-
-
Fu, D.Y.1
Wang, Z.M.2
Li, C.3
-
120
-
-
0035503031
-
Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers
-
Xu XL, Wu LC, Du F, et al. Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res, 2001,61:7943-7949.
-
(2001)
Cancer Res
, vol.61
, pp. 7943-7949
-
-
Xu, X.L.1
Wu, L.C.2
Du, F.3
-
121
-
-
0035879017
-
Hypermethylation leads to silencing of the SYK gene in human breast cancer
-
Yuan Y, Mendez R, Sahin A, et al. Hypermethylation leads to silencing of the SYK gene in human breast cancer. Cancer Res, 2001,61:5558-5561.
-
(2001)
Cancer Res
, vol.61
, pp. 5558-5561
-
-
Yuan, Y.1
Mendez, R.2
Sahin, A.3
-
122
-
-
0033558192
-
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
-
Bachman KE, Herman JG, Corn PG, et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res, 1999,59:798-802.
-
(1999)
Cancer Res
, vol.59
, pp. 798-802
-
-
Bachman, K.E.1
Herman, J.G.2
Corn, P.G.3
-
123
-
-
74549180973
-
Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers
-
Antill YC, Mitchell G, Johnson SA, et al. Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev, 2010,19:265-274.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 265-274
-
-
Antill, Y.C.1
Mitchell, G.2
Johnson, S.A.3
-
124
-
-
0033676843
-
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-in duced gene silencing in human breast cancers
-
Conway KE, McConnell BB, Bowring CE, et al. TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-in duced gene silencing in human breast cancers. Cancer Res, 2000,60:6236-6242.
-
(2000)
Cancer Res
, vol.60
, pp. 6236-6242
-
-
Conway, K.E.1
McConnell, B.B.2
Bowring, C.E.3
-
125
-
-
40949114150
-
The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer
-
Ai L, Kim WJ, Demircan B, et al. The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer. Carcinogenesis, 2008,29:510-518.
-
(2008)
Carcinogenesis
, vol.29
, pp. 510-518
-
-
Ai, L.1
Kim, W.J.2
Demircan, B.3
-
126
-
-
79551647934
-
Functional characterization of Trip10 in cancer cell growth and survival
-
Hsu CC, Leu YW, Tseng MJ, et al. Functional characterization of Trip10 in cancer cell growth and survival. J Biomed Sci, 2011,18:12.
-
(2011)
J Biomed Sci
, vol.18
, pp. 12
-
-
Hsu, C.C.1
Leu, Y.W.2
Tseng, M.J.3
-
127
-
-
0036531824
-
Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer
-
Li Z, Meng ZH, Chandrasekaran R, et al. Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer. Cancer Res, 2002,62:1939-1943.
-
(2002)
Cancer Res
, vol.62
, pp. 1939-1943
-
-
Li, Z.1
Meng, Z.H.2
Chandrasekaran, R.3
-
128
-
-
12944275670
-
High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer
-
Ferguson AT, Evron E, Umbricht CB, et al. High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proc Natl Acad Sci U S A, 2000,97: 6049-6054.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6049-6054
-
-
Ferguson, A.T.1
Evron, E.2
Umbricht, C.B.3
-
129
-
-
0035821727
-
Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer
-
Umbricht CB, Evron E, Gabrielson E, et al. Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. Oncogene, 2001,20:3348-3353.
-
(2001)
Oncogene
, vol.20
, pp. 3348-3353
-
-
Umbricht, C.B.1
Evron, E.2
Gabrielson, E.3
|