Modulation of drug release by utilizing pH-independent matrix system comprising water soluble drug verapamil hydrochloride

Pakistan Journal of Pharmaceutical Sciences

Volumn 26, Issue 1, 2013, Pages 137-144

  Baviskar, Dheeraj ^a   Sharma, Rajesh ^b   Jain, Dinesh ^c  

^a Institute of Pharmaceutical Education   (India)

^b DEVI AHILYA UNIVERSITY   (India)

^c Rajendra Nagar   (India)

Author keywords

Eudragit RSPO; HPMC K 15M; In vitro drug release; In vivo evaluation; Matrix tablets; Optimization; Verapamil HCl

Indexed keywords

EUDRAGIT; HYDROXYLPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; METHYLCELLULOSE; POVIDONE; UNCLASSIFIED DRUG; VERAPAMIL;

ADULT; AREA UNDER THE CURVE; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG EFFICACY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HUMAN; HUMAN EXPERIMENT; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MATRIX TABLET; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PATIENT COMPLIANCE; PH; REPRODUCIBILITY; SUSTAINED RELEASE FORMULATION; TABLET COMPRESSION; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ADMINISTRATION, ORAL; ADULT; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MALE; METHYLCELLULOSE; MODELS, CHEMICAL; POLYMERS; POLYMETHACRYLIC ACIDS; POVIDONE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS; TECHNOLOGY, PHARMACEUTICAL; VERAPAMIL; WATER; X-RAY DIFFRACTION; YOUNG ADULT;

EID: 84872189884     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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