Genome-wide association studies in psychiatry: What have we learned?

British Journal of Psychiatry

Volumn 202, Issue 1, 2013, Pages 1-4

  Collins, Ann L ^a   Sullivan, Patrick F ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; CYTOCHROME P450 2A6; MICRORNA;

ALCOHOL CONSUMPTION; BIPOLAR DISORDER; CALCIUM SIGNALING; CHOLESTEROL METABOLISM; COPY NUMBER VARIATION; ENTERITIS; ENVIRONMENTAL FACTOR; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEREDITY; HUMAN; INNATE IMMUNITY; KNOWLEDGE; MAJOR DEPRESSION; MENTAL DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; PSYCHIATRY; REVIEW; RISK FACTOR; SCHIZOPHRENIA;

GENOME-WIDE ASSOCIATION STUDY; HUMANS; MENTAL DISORDERS; PSYCHIATRY;

EID: 84872168060     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.112.117002     Document Type: Review

References (9)

1. Corvin A, Craddock N, Sullivan PF. Genome-wide association studies: a primer. Psychol Med 2010; 40: 1063-77.
2. National Human Genome Reseach Institute. A Catalog of Published Genome-Wide Association Studies. National Human Genome Reseach Institute, no date (http://www.genome.gov/26525384).
3. Psychiatric GWAS Consortium. A framework for interpreting genomewide association studies of psychiatric disorders. Mol Psychiatry 2009; 14: 10-7.
4. Sullivan P, de Geus E, Willemsen G, James MR, Smit JH, Zandbelt T, et al. Genomewide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry 2009; 14: 359-75.
5. Major Depressive Disorder Working Group of the PGC. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry 2012; April 3 (Epub ahead of print).
6. Sullivan PF, Daly MJ, O'Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet 2012; 13: 537-51.
7. Collins AL, Kim Y, Sklar P, O'Donovan MC, Sullivan PF. Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results. Psychol Med 2012; 42: 607-16.
8. Visscher PM, Brown MA, McCarthy MI, Yang J. Five years of GWAS discovery. Am J Hum Genet 2012; 90: 7-24.
9. Sullivan PF. Schizophrenia as a pathway disease. Nat Med 2012; 18: 210-1.