Comparative genomics of early-diverging brucella strains reveals a novel lipopolysaccharide biosynthesis pathway

mBio

Volumn 3, Issue 5, 2012, Pages

  Wattam, Alice R ^a   Inzana, Thomas J ^b   Williams, Kelly P ^c   Mane, Shrinivasrao P ^a   Shukla, Maulik ^a   Almeida, Nalvo F ^d   Dickerman, Allan W ^a   Mason, Steven ^a   Moriyón, Ignacio ^e   O'Callaghan, David ^f,g   Whatmore, Adrian M ^h   Sobral, Bruno W ^a   Tiller, Rebekah V ⁱ   Hoffmaster, Alex R ⁱ   Frace, Michael A ⁱ   de Castro, Cristina ^j   Molinaro, Antonio ^j   Boyle, Stephen M ^b   De, Barun K ⁱ   Setubal, João C ^a,k  

^a VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

^b CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^c SANDIA NATIONAL LABORATORIES   (United States)

^d FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

^e UNIVERSITY OF NAVARRA   (Spain)

^f CHU Nîmes   (France)

^g UNIV MONTPELLIER   (France)

^h VETERINARY LABORATORIES AGENCY   (United Kingdom)

ⁱ CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^j UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^k UNIVERSITY OF SÃO PAULO   (Brazil)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; LIPOPOLYSACCHARIDE;

ANIMAL; ARTICLE; BACTERIAL GENOME; BIOLOGY; BIOSYNTHESIS; BRUCELLA; CHEMISTRY; COMPARATIVE STUDY; DNA SEQUENCE; GENETICS; GENOMICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; RODENT; ERROR; PRIORITY JOURNAL;

ANIMALS; BIOSYNTHETIC PATHWAYS; BRUCELLA; COMPUTATIONAL BIOLOGY; DNA, BACTERIAL; GENOME, BACTERIAL; GENOMICS; HUMANS; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; RODENTIA; SEQUENCE ANALYSIS, DNA;

BRUCELLA;

EID: 84872154282     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00246-12     Document Type: Article

References (60)

1. Morgan WJ, Corbel MJ. 1976. Recommendations for the description of species and biotypes of the genus Brucella. Dev. Biol. Stand. 31:27-37.
2. Palva ET, Mäkelä PH. 1980. Lipopolysaccharide heterogeneity in Salmonella typhimurium analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis. Eur. J. Biochem. 107:137-143.
3. Boschiroli ML, Foulongne V, O'Callaghan D. 2001. Brucellosis: a worldwide zoonosis. Curr. Opin. Microbiol. 4:58-64.
4. Corbel MJ. 1997. Brucellosis: an overview. Emerg. Infect. Dis. 3:213-221.
5. El-Olemy GM, Atta AA, Mahmoud WH, Hamzah EG. 1984. Brucellosis in man-II. Isolation of the causative organisms with special reference to blood picture and urine constituents. Dev. Biol. Stand. 56:573-578.
6. Pappas G, Akritidis N, Bosilkovski M, Tsianos E. 2005. Medical progress: brucellosis. N Engl J. Med. 352:2325-2336.
7. Foster G, Osterman BS, Godfroid J, Jacques I, Cloeckaert A. 2007. Brucella ceti sp. nov. and Brucella pinnipedialis sp. nov. for Brucella strains with cetaceans and seals as their preferred hosts. Int. J. Syst. Evol. Micro-biol. 57:2688-2693.
8. Jahans KL, Foster G, Broughton ES. 1997. The characterisation of Bru-cella strains isolated from marine mammals. Vet. Microbiol. 57:373-382.
9. Jiménez de Bagüés MP, et al. 2010. The new species Brucella microti replicatesin macrophages and causes death inmurine modelsof infection. J. Infect. Dis. 202:3-10.
10. Audic S, Lescot M, Claverie JM, Scholz HC. 2009. Brucella microti: the genome sequence of an emerging pathogen. BMC Genomics 10:352.
11. Hubálek Z, et al. 2007. Brucellosis of the common vole (Microtus arvalis). Vector-Borne Zoonotic Dis. 7:679-687.
12. Le Flèche P, et al. 2006. Evaluation and selection of tandem repeat loci for a Brucella MLVA typing assay. BMC Microbiol. 6:9.
13. Maquart M, et al. 2009. MLVA-16 typing of 295 marine mammal Brucella isolates from different animal and geographic origins identifies 7 major groups within Brucella ceti and Brucella pinnipedialis. BMC Microbiol. 9:145.
14. Scholz HC, et al. 2008. Brucella microti sp. nov., isolated from the common vole Microtus arvalis. Int. J. Syst. Evol. Microbiol. 58:375-382.
15. De BK, et al. 2008. Novel Brucella strain (BO1) associated with a prosthetic breast implant infection. J. Clin. Microbiol. 46:43-49.
16. Tiller RV, et al. 2010. Identification of an unusual Brucella strain (BO2) from a lung biopsy in a 52 year-old patient with chronic destructive pneumonia. BMC Microbiol. 10:23.
17. Scholz HC, et al. 2010. Brucella inopinata sp. nov., isolated from a breast implant infection. Int. J. Syst. Evol. Microbiol. 60:801-808.
18. Paquet JY, et al. 2001. Molecular, antigenic, and functional analyses of Omp2b porin size variants of Brucella spp. J. Bacteriol. 183:4839-4847.
19. Cook I, Campbell RW, Barrow G. 1966. Brucellosis in North Queensland rodents. Aust. Vet. J. 42:5-8.
20. Tiller RV, et al. 2010. Characterization of novel Brucella strains originating from wild native rodent species in North Queensland, Australia. Appl. Environ. Microbiol. 76:5837-5845.
21. Scholz HC, et al. 2008. Genetic diversity and phylogenetic relationships of bacteria belonging to the Ochrobactrum-Brucella group by recA and 16S rRNA gene-based comparative sequence analysis. Syst. Appl. Microbiol. 31:1-16.
22. Conde-Álvarez R, et al. 2012. The lipopolysaccharide core of Brucella abortus acts as ashield against innate immunity recognition. PLoS Pathog. 8:e1002675.
23. Paulsen IT, et al. 2002. The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts. Proc. Natl. Acad. Sci. U. S. A. 99:13148-13153.
24. Mackiewicz P, Zakrzewska-Czerwinska J, Zawilak A, Dudek MR, Cebrat S. 2004. Where does bacterial replication start? Rules for predicting the oriC region. Nucleic Acids Res. 32:3781-3791.
25. Velasco J, et al. 1998. Evaluation of the relatedness of Brucella spp. and Ochrobactrum anthropi and description of Ochrobactrum intermedium sp. nov., a new species with a closer relationship to Brucella spp. Int. J. Syst. Bacteriol. 48:-759-768.
26. Wattam AR, et al. 2009. Analysis of ten Brucella genomes reveals evidence for horizontal gene transfer despite a preferred intracellular lifestyle. J. Bacteriol. 191:3569-3579.
27. Díaz E, Ferrández A, Prieto MA, García JL. 2001. Biodegradation of aromatic compounds by Escherichia coli. Microbiol. Mol. Biol. Rev. 65: 523-569.
28. Giraud MF, Naismith JH. 2000. The rhamnose pathway. Curr. Opin. Struct. Biol. 10:687-696.
29. Godfroid F, et al. 2000. Genetic organisation of the lipopolysaccharide O-antigen biosynthesis region of Brucella melitensis 16M (wbk). Res. Mi-crobiol. 151:655-668.
30. González D, et al. 2008. Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PLoS One 3:e2760.
31. Zygmunt MS, Blasco JM, Letesson JJ, Cloeckaert A, Moriyón I. 2009. DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers. BMC Microbiol. 9:92.
32. Cardoso PG, Macedo GC, Azevedo V, Oliveira SC. 2006. Brucella spp noncanonical LPS: structure, biosynthesis, and interaction with host immune system. Microb. Cell Fact. 5:13.
33. Tsukioka Y, Yamashita Y, Oho T, Nakano Y, Koga T. 1997. Biological function of the dTDP-rhamnose synthesis pathway in Streptococcus mu-tans. J. Bacteriol. 179:1126-1134.
34. Reeves P. 1993. Evolution of Salmonella O antigen variation by interspecific gene transfer on a large scale. Trends Genet. 9:17-22.
35. Velasco J, Moll H, Vinogradov EV, Moriyón I, Zähringer U. 1996. Determination of the O-specific polysaccharide structure in the lipopoly-saccharide of Ochrobactrum anthropi LMG 3331. Carbohydr. Res. 287: 123-126.
36. Raetz CRH, Whitfield C. 2002. Lipopolysaccharide endotoxins. Annu. Rev. Biochem. 71:635-700.
37. Gil-Ramirez Y. 2011. El lipopolisacárido de Brucella: análisis genético de un factor de virulencia. Ph.D. thesis. Universidad de Navarra, Navarra, Spain.
38. Iriarte M, et al. 2004. Brucella lipopolysaccharide: structure, biosynthesis and genetics, p 159-191. Horizon Bioscience, Wymondham, Norfolk, UK.
39. Zygmunt MS, Jacques I, Bernardet N, Cloeckaert A. 3 July 2012. Lipopolysaccharide heterogeneity in the atypical group of novel emerging Brucella species. Clin. Vaccine Immunol.
40. Caroff M, Bundle DR, Perry MB. 1984. Structure of the O-chain of the phenol-phase soluble cellular lipopolysaccharide of Yersinia enterocolitica serotype O:9. Eur. J. Biochem. 139:195-200.
41. Perry MB, Bundle DR. 1990. Lipopolysaccharide antigens and carbohydrates of Brucella, p 76-88. In Adams LG (ed), Advances in brucellosis research. Texas A & M University Press, College Station, TX.
42. Moreno E, Speth SL, Jones LM, Berman DT. 1981. Immunochemical characterization of Brucella lipopolysaccharides and polysaccharides. Infect. Immun. 31:214-222.
43. Lapaque N, Moriyon I, Moreno E, Gorvel JP. 2005. Brucella lipopoly-saccharide acts as a virulence factor. Curr. Opin. Microbiol. 8:60-66.
44. Porte F, Naroeni A, Ouahrani-Bettache S, Liautard JP. 2003. Role of the Brucella suis lipopolysaccharide O antigen in phagosomal genesis and in inhibitionof phagosome-lysosome fusioninmurine macrophages. Infect. Immun. 71:1481-1490.
45. Ficht T. 2010. Brucella taxonomy and evolution. Future Microbiol. 5:859-866.
46. Aziz RK, et al. 2008. The RAST server: rapid annotations using subsystems technology. BMC Genomics 9:75.
47. Altschul SF, et al. 1997. Gapped BLAST and psi-blast: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
48. Castresana J. 2000. Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol. Biol. Evol. 17:540-552.
49. Stamatakis A. 2006. RAxML-VI-HPC: maximum likelihood-based phy-logenetic analyses with thousandsoftaxa and mixed models. Bioinformat-ics 22:2688-2690.
50. Li J, et al. 2007. Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS. Microbiology 153: 3141-3153.
51. Inzana TJ. 1983. Electrophoretic heterogeneity and interstrain variation of the lipopolysaccharide of Haemophilus influenzae. J. Infect. Dis. 148: 492-499.
52. Tsai CM, Frasch CE. 1982. A sensitive silver stain for detecting lipopoly-saccharides in polyacrylamide gels. Anal. Biochem. 119:115-119.
53. Inzana TJ, Mathison B. 1987. Serotype specificity and immunogenicity of the capsular polymer of Haemophilus pleuropneumoniaeserotype 5. Infect. Immun. 55:1580-1587.
54. Schurig GG, Hammerberg C, Finkler BR. 1984. Monoclonal antibodies toBrucellasurface antigens associated with the smooth lipopolysaccharide complex. Am. J. Vet. Res. 45:967-971.
55. De Castro C, Parrilli M, Holst O, Molinaro A. 2010. Microbe-associated molecular patterns in innate immunity: extraction and chemical analysis of gram-negative bacterial lipopolysaccharides. Methods Enzymol. 480: 89-115.
56. Whatmore AM. 2009. Current understanding of the genetic diversity of Brucella, an expanding genus of zoonotic pathogens. Infect. Genet. Evol. 9:1168-1184.
57. Snyder EE, et al. 2007. PATRIC: the VBI PathoSystems Resource Integration Center. Nucleic Acids Res. 35:D401-D406.
58. Gillespie JJ, et al. 2011. PATRIC: the comprehensive bacterial bioinfor-matics resource with a focus on human pathogenic species. Infect. Im-mun. 79:4286-4298.
59. Li L, Stoeckert CJ, Roos DS. 2003. OrthoMCL: identification of ortholog groups for eukaryotic genomes. Genome Res. 13:2178-2189.
60. Edgar RC. 2004. MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5:1-19.