Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: The PROSPECT study

EuroIntervention

Volumn 8, Issue 8, 2012, Pages 929-938

  Ruiz García, Juan ^a,b   Lerman, Amir ^a   Weisz, Giora ^c   Maehara, Akiko ^c   Mintz, Gary S ^c   Fahy, Martin ^c   Xu, Ke ^c   Lansky, Alexandra J ^d   Cristea, Ecaterina ^c   Farah, Tony G ^e   Teles, Rui ^f   Botker, Hans Erik ^g   Templin, Barry ^h   Zhang, Zhen ^h   De Bruyne, Bernard ⁱ   Serruys, Patrick W ^j   Stone, Gregg W ^c  

^a MAYO CLINIC   (United States)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c NewYork Presbyterian Hospital   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ALLEGHENY GENERAL HOSPITAL   (United States)

^f HOSPITAL DE SANTA CRUZ   (Portugal)

^g AARHUS UNIVERSITY HOSPITAL   (Denmark)

^h ABBOTT VASCULAR   (United States)

ⁱ OLV HOSPITAL   (Belgium)

^j ERASMUS MEDICAL CENTER   (Netherlands)

more..

Author keywords

Acute coronary syndrome; Elderly; Fibroatheroma; Necrotic core; Plaque burden; Women

Indexed keywords

ACUTE CORONARY SYNDROME; ADULT; AGE; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; FEMALE; FOLLOW UP; HEART ARREST; HEART DEATH; HEART INFARCTION; HOSPITAL READMISSION; HUMAN; INTRAVASCULAR ULTRASOUND; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; SEX DIFFERENCE;

ACUTE CORONARY SYNDROME; AGE FACTORS; AGED; CALCINOSIS; CORONARY ANGIOGRAPHY; FEMALE; FIBROSIS; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NECROSIS; PERCUTANEOUS CORONARY INTERVENTION; PLAQUE, ATHEROSCLEROTIC; RISK FACTORS; SEX FACTORS; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 84872149670     PISSN: 1774024X     EISSN: 19696213     Source Type: Journal    
DOI: 10.4244/EIJV8I8A142     Document Type: Article

References (40)

1. Lakatta EG, Levy D. Arterial and cardiac aging: major share-holders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation. 2003;107:139-46.
2. Burke AP, Farb A, Pestaner J, Malcom GT, Zieske A, Kutys R, Smialek J, Virmani R. Traditional risk factors and the incidence of sudden coronary death with and without coronary thrombosis in blacks. Circulation. 2002;105:419-24.
3. Garcia-Garcia HM, Serruys PW, Mintz GS, Saito S, Klaus V, Margolis P, Carlier S, Goedhart D, Schwartz R. Synergistic effect of cardiovascular risk factors on necrotic core in coronary arteries: a report from the global intravascular radiofrequency data analysis registry. JACC Cardiovasc Imaging. 2009;2:629-36.
4. Piro M, Della Bona R, Abbate A, Biasucci LM, Crea F. Sexrelated differences in myocardial remodeling. J Am Coll Cardiol. 2010;55:1057-65.
5. Lam CS, Xanthakis V, Sullivan LM, Lieb W, Aragam J, Redfield MM, Mitchell GF, Benjamin EJ, Vasan RS. Aortic root remodeling over the adult life course: longitudinal data from the Framingham Heart Study. Circulation. 2010;122:884-90.
6. Kajstura J, Gurusamy N, Ogorek B, Goichberg P, Clavo-Rondon C, Hosoda T, D'Amario D, Bardelli S, Beltrami AP, Cesselli D, Bussani R, del Monte F, Quaini F, Rota M, Beltrami CA, Buchholz BA, Leri A, Anversa P. Myocyte turnover in the aging human heart. Circ Res. 2010;107:1374-86.
7. Parker BA, Kalasky MJ, Proctor DN. Evidence for sex differences in cardiovascular aging and adaptive responses to physical activity. Eur J Appl Physiol. 2010;110:235-46.
8. Roger VL, Weston SA, Killian JM, Pfeifer EA, Belau PG, Kottke TE, Frye RL, Bailey KR, Jacobsen SJ. Time trends in the prevalence of atherosclerosis: a population-based autopsy study. Am J Med. 2001;110:267-73.
9. Nemetz PN, Roger VL, Ransom JE, Bailey KR, Edwards WD, Leibson CL. Recent trends in the prevalence of coronary disease: a population-based autopsy study of nonnatural deaths. Arch Intern Med. 2008;168:264-70.
10. Burke AP, Farb A, Malcom G, Virmani R. Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis. Am Heart J. 2001;141:S58-62.
11. Mautner SL, Lin F, Mautner GC, Roberts WC. Comparison in women versus men of composition of atherosclerotic plaques in native coronary arteries and in saphenous veins used as aortocoronary conduits. J Am Coll Cardiol. 1993;21:1312-18.
12. Vaccarino V, Parsons L, Every NR, Barron HV, Krumholz HM. Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. N Engl J Med. 1999;341:217-25.
13. Vaccarino V, Krumholz HM, Yarzebski J, Gore JM, Goldberg RJ. Sex differences in 2-year mortality after hospital discharge for myocardial infarction. Ann Intern Med. 2001;134:173-81.
14. Champney KP, Frederick PD, Bueno H, Parashar S, Foody J, Merz CN, Canto JG, Lichtman JH, Vaccarino V, Investigators N. The joint contribution of sex, age and type of myocardial infarction on hospital mortality following acute myocardial infarction. Heart. 2009;95:895-9.
15. Lawesson SS, Stenestrand U, Lagerqvist B, Wallentin L, Swahn E. Gender perspective on risk factors, coronary lesions and long-term outcome in young patients with ST-elevation myocardial infarction. Heart. 2010;96:453-9.
16. Glaser R, Selzer F, Faxon DP, Laskey WK, Cohen HA, Slater J, Detre KM, Wilensky RL. Clinical progression of incidental, asymptomatic lesions discovered during culprit vessel coronary intervention. Circulation. 2005;111:143-9.
17. Vaccarino V. Ischemic heart disease in women: many questions, few facts. Circ Cardiovasc Qual Outcomes. 2010;3:111-5.
18. Garcia-Garcia HM, Mintz GS, Lerman A, Vince DG, Margolis MP, van Es GA, Morel MA, Nair A, Virmani R, Burke AP, Stone GW, Serruys PW. Tissue characterisation using intravascular radiofrequency data analysis: recommendations for acquisition, analysis, interpretation and reporting. EuroIntervention. 2009;5:177-89.
19. Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW, Investigators P. A prospective natural-history study of coronary atherosclerosis. N Engl J Med. 2011;364:226-35.
20. Wu X, Maehara A, Mintz GS, Kubo T, Xu K, Choi SY, He Y, Guo N, Moses JW, Leon MB, De Bruyne B, Serruys PW, Stone GW. Virtual histology intravascular ultrasound analysis of non-culprit attenuated plaques detected by grayscale intravascular ultrasound in patients with acute coronary syndromes. Am J Cardiol. 2010;105:48-53.
21. van Oostrom O, Velema E, Schoneveld AH, de Vries JP, de Bruin P, Seldenrijk CA, de Kleijn DP, Busser E, Moll FL, Verheijen JH, Virmani R, Pasterkamp G. Age-related changes in plaque composition: a study in patients suffering from carotid artery stenosis. Cardiovasc Pathol. 2005;14:126-34.
22. Hong YJ, Jeong MH, Ahn Y, Sim DS, Chung JW, Cho JS, Yoon NS, Yoon HJ, Moon JY, Kim KH, Park HW, Kim JH, Cho JG, Park JC, Kang JC. Age-related differences in intravascular ultrasound findings in 1,009 coronary artery disease patients. Circ J. 2008;72:1270-5.
23. McClelland RL, Chung H, Detrano R, Post W, Kronmal RA. Distribution of coronary artery calcium by race, gender, and age: Results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2006;113:30-7.
24. Bamberg F, Dannemann N, Shapiro MD, Seneviratne SK, Ferencik M, Butler J, Koenig W, Nasir K, Cury RC, Tawakol A, Achenbach S, Brady TJ, Hoffmann U. Association between cardiovascular risk profiles and the presence and extent of different types of coronary atherosclerotic plaque as detected by multidetector computed tomography. Arterioscler Thromb Vasc Biol. 2008;28:568-74.
25. Dey S, Flather MD, Devlin G, Brieger D, Gurfinkel EP, Steg PG, Fitzgerald G, Jackson EA, Eagle KA; Global Registry of Acute Coronary Events investigators. Sex-related differences in the presentation, treatment and outcomes among patients with acute coronary syndromes: the Global Registry of Acute Coronary Events. Heart. 2009;95:20-6.
26. Vaccarino V, Parsons L, Peterson ED, Rogers WJ, Kiefe CI, Canto J. Sex differences in mortality after acute myocardial infarction: changes from 1994 to 2006. Arch Intern Med. 2009;169:1767-74.
27. Shaw LJ, Bugiardini R, Merz CN. Women and ischemic heart disease: evolving knowledge. J Am Coll Cardiol. 2009;54:1561-75.
28. Gurfinkel E, Vigliano C, Janavel JV, Fornoni D, Caponi G, Meckert PC, Bertolotti A, Favaloro R, Laguens R. Presence of vulnerable coronary plaques in middle-aged individuals who suffered a brain death. Eur Heart J. 2009;30:2845-53.
29. Nicholls SJ, Wolski K, Sipahi I, Schoenhagen P, Crowe T, Kapadia SR, Hazen SL, Tuzcu EM, Nissen SE. Rate of progression of coronary atherosclerotic plaque in women. J Am Coll Cardiol. 2007;49:1546-51.
30. Han SH, Bae JH, Holmes DR Jr, Lennon RJ, Eeckhout E, Barsness GW, Rihal CS, Lerman A. Sex differences in atheroma burden and endothelial function in patients with early coronary atherosclerosis. Eur Heart J. 2008;29:1359-69.
31. Pundziute G, Schuijf JD, van Velzen JE, Jukema JW, van Werkhoven JM, Nucifora G, van der Kley F, Kroft LJ, de Roos A, Boersma E, Reiber JH, Schalij MJ, van der Wall EE, Bax JJ. Assessment with multi-slice computed tomography and gray-scale and virtual histology intravascular ultrasound of gender-specific differences in extent and composition of coronary atherosclerotic plaques in relation to age. Am J Cardiol. 2010;105:480-6.
32. Kubo T, Maehara A, Mintz GS, Doi H, Tsujita K, Choi SY, Katoh O, Nasu K, Koenig A, Pieper M, Rogers JH, Wijns W, Bose D, Margolis MP, Moses JW, Stone GW, Leon MB. The dynamic nature of coronary artery lesion morphology assessed by serial virtual histology intravascular ultrasound tissue characterization. J Am Coll Cardiol. 2010;55:1590-7.
33. Qian J, Maehara A, Mintz GS, Margolis MP, Lerman A, Rogers J, Banai S, Kazziha S, Castellanos C, Dani L, Fahy M, Stone GW, Leon MB. Impact of gender and age on in vivo virtual histology-intravascular ultrasound imaging plaque characterization (from the global virtual histology intravascular ultrasound [VH-IVUS] registry). Am J Cardiol. 2009;103:1210-4.
34. Shaw LJ, Bairey Merz CN, Pepine CJ, Reis SE, Bittner V, Kelsey SF, Olson M, Johnson BD, Mankad S, Sharaf BL, Rogers WJ, Wessel TR, Arant CB, Pohost GM, Lerman A, Quyyumi AA, Sopko G; WISE Investigators. Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: Gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J Am Coll Cardiol. 2006;47:S4-S20.
35. Bairey Merz CN, Shaw LJ, Reis SE, Bittner V, Kelsey SF, Olson M, Johnson BD, Pepine CJ, Mankad S, Sharaf BL, Rogers WJ, Pohost GM, Lerman A, Quyyumi AA, Sopko G; WISE Investigators. Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: Gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular coronary disease. J Am Coll Cardiol. 2006;47:S21-9.
36. Nicholls SJ, Tuzcu EM, Crowe T, Sipahi I, Schoenhagen P, Kapadia S, Hazen SL, Wun CC, Norton M, Ntanios F, Nissen SE. Relationship between cardiovascular risk factors and atherosclerotic disease burden measured by intravascular ultrasound. J Am Coll Cardiol. 2006;47:1967-75.
37. Philipp S, Bose D, Wijns W, Marso SP, Schwartz RS, Konig A, Lerman A, Garcia-Garcia HM, Serruys PW, Erbel R. Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry. Eur Heart J. 2010;31:196-202.
38. Zimmermann S, Ruthrof S, Nowak K, Alff A, Klinghammer L, Schneider R, Ludwig J, Pfahlberg AB, Daniel WG, Flachskampf FA. Short-term prognosis of contemporary interventional therapy of ST-elevation myocardial infarction: does gender matter? Clin Res Cardiol. 2009;98:709-15.
39. Duvernoy CS, Smith DE, Manohar P, Schaefer A, Kline-Rogers E, Share D, McNamara R, Gurm HS, Moscucci M. Gender differences in adverse outcomes after contemporary percutaneous coronary intervention: an analysis from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) percutaneous coronary intervention registry. Am Heart J. 2010;159:677-83.
40. Sheiban I, La Spina C, Cavallero E, Biondi-Zoccai G, Colombo F, Palmerini T, Marzocchi A, Tamburino C, Margheri M, Vecchi G, Sangiorgi G, Santarelli A, Bartorelli AL, Briguori C, Vignali L, di Pede F, Ramondo A, Fantoni C, de Carlo M, Falsini G, Benassi A, Palmieri C, Filippone V, Sangiorgi D, de Servi S. Sex-related differences in patients undergoing percutaneous unprotected left main stenting. EuroIntervention. 2010;5: 795-800.