Brain magnetic resonance in experimental acute-on-chronic liver failure

Liver International

Volumn 33, Issue 2, 2013, Pages 294-300

  Chavarria, Laia ^a,b,c   Oria, Marc ^a,b,c   Romero Giménez, Jordi ^a   Alonso, Juli ^a,b   Lope Piedrafita, Silvia ^c,d   Cordoba, Juan ^a,b,c  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

Bile duct ligation; Cirrhosis; Diffusion imaging; Gravimetry; Proton spectroscopy

Indexed keywords

CHOLINE; GLUTAMINE; INOSITOL; LIPOPOLYSACCHARIDE;

ACUTE ON CHRONIC LIVER FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BRAIN EDEMA; BRAIN WATER; CONTROLLED STUDY; DISEASE COURSE; GRAVIMETRY; IN VIVO STUDY; MALE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSMOSIS; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BILE DUCTS; BRAIN EDEMA; LIGATION; LIPOPOLYSACCHARIDES; LIVER FAILURE, ACUTE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84872140657     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12032     Document Type: Article

References (29)

1. Chavarria L, Alonso J, Rovira A, Cordoba J. Neuroimaging in acute liver failure. Neurochem Int 2011; 59: 1175-80.
2. Schaefer PW, Grant PE, Gonzalez RG. Diffusion-weighted MR imaging of the brain. Radiology 2000; 217: 331-45.
3. Schwarcz A, Ursprung Z, Berente Z, et al. In vivo brain edema classification: new insight offered by large b-value diffusion-weighted MR imaging. J Magn Reson Imaging 2007; 25: 26-31.
4. Chavarria L, Oria M, Romero-Gimenez J, et al. Diffusion tensor imaging supports the cytotoxic origin of brain edema in a rat model of acute liver failure. Gastroenterology 2010; 138: 1566-73.
5. Cauli O, Lopez-Larrubia P, Rodrigo R, et al. Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats. Gastroenterology 2011; 140: 638-45.
6. Cordoba J, Gottstein J, Blei AT. Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: implications for ammonia-induced brain edema. Hepatology 1996; 24: 919-23.
7. Rai V, Nath K, Saraswat VA, et al. Measurement of cytotoxic and interstitial components of cerebral edema in acute hepatic failure by diffusion tensor imaging. J Magn Reson Imaging 2008; 28: 334-41.
8. Nath K, Saraswat VA, Krishna YR, et al. Quantification of cerebral edema on diffusion tensor imaging in acute-on-chronic liver failure. NMR Biomed 2008; 21: 713-22.
9. Lodi R, Tonon C, Stracciari A, et al. Diffusion MRI shows increased water apparent diffusion coefficient in the brains of cirrhotics. Neurology 2004; 62: 762-6.
10. Bosoi CR, Yang X, Huynh J, et al. Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure. Free Radic Biol Med 2012; 52: 1228-35.
11. Wright G, Davies NA, Shawcross DL, et al. Endotoxemia produces coma and brain swelling in bile duct ligated rats. Hepatology 2007; 45: 1517-26.
12. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993; 30: 672-9.
13. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000; 13: 129-53.
14. Marmarou A, Poll W, Shulman K, Bhagavan H. A simple gravimetric technique for measurement of cerebral edema. J Neurosurg 1978; 49: 530-7.
15. Butterworth RF, Norenberg MD, Felipo V, et al. Experimental models of hepatic encephalopathy: ISHEN guidelines. Liver Int 2009; 29: 783-8.
16. LeBihan D. The 'wet mind': water and functional neuroimaging. Phys Med Biol 2007; 52: R57-R90.
17. Jover R, Rodrigo R, Felipo V, et al. Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: a model of hepatic encephalopathy in cirrhosis. Hepatology 2006; 43: 1257-66.
18. Cordoba J, Blei AT. Brain edema and hepatic encephalopathy. Semin Liver Dis 1996; 16: 271-80.
19. Clemmesen JO, Larsen FS, Kondrup J, Hansen BA, Ott P. Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology 1999; 29: 648-53.
20. Wright G, Soper R, Brooks HF, et al. Role of aquaporin-4 in the development of brain oedema in liver failure. J Hepatol 2010; 53: 91-7.
21. Douglass A, Al MH, Record C. Amino acid challenge in patients with cirrhosis: a model for the assessment of treatments for hepatic encephalopathy. J Hepatol 2001; 34: 658-64.
22. Albrecht J, Norenberg MD. Glutamine: a Trojan horse in ammonia neurotoxicity. Hepatology 2006; 44: 788-94.
23. Chatauret N, Zwingmann C, Rose C, Leibfritz D, Butterworth RF. Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study. Gastroenterology 2003; 125: 815-24.
24. Tofteng F, Larsen FS. Monitoring extracellular concentrations of lactate, glutamate, and glycerol by in vivo microdialysis in the brain during liver transplantation in acute liver failure. Liver Transpl 2002; 8: 302-5.
25. Preuss M. An energy-failure based brain edema concept. Med Hypotheses. 2012; 79 259-60.
26. Zwingmann C, Butterworth R. An update on the role of brain glutamine synthesis and its relation to cell-specific energy metabolism in the hyperammonemic brain: further studies using NMR spectroscopy. Neurochem Int 2005; 47: 19-30.
27. Barba I, Chatauret N, Garcia-Dorado D, Cordoba J. A 1H nuclear magnetic resonance-based metabonomic approach for grading hepatic encephalopathy and monitoring the effects of therapeutic hypothermia in rats. Liver Int 2008; 28: 1141-8.
28. Garcia-Martinez R, Rovira A, Alonso J, et al. Hepatic encephalopathy is associated with posttransplant cognitive function and brain volume. Liver Transpl 2011; 17: 38-46.
29. Brugieres P, Thomas P, Maraval A, et al. Water diffusion compartmentation at high b values in ischemic human brain. AJNR Am J Neuroradiol 2004; 25: 692-8.