Differentiated umbilical cord matrix stem cells as a new in vitro model to study early events during hepatitis B virus infection

Hepatology

Volumn 57, Issue 1, 2013, Pages 59-69

  Paganelli, Massimiliano ^a   Dallmeier, Kai ^a   Nyabi, Omar ^a   Scheers, Isabelle ^a   Kabamba, Benoît ^b   Neyts, Johan ^a   Goubau, Patrick ^b   Najimi, Mustapha ^a   Sokal, Etienne M ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; CYTOCHROME P450 3A4; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; TENOFOVIR; VIRUS RNA;

ANTIVIRAL THERAPY; ARTICLE; CELL DIFFERENTIATION; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; PRIORITY JOURNAL; STEM CELL; UMBILICAL CORD MATRIX STEM CELL; UPREGULATION; VIRUS REPLICATION;

ASIALOGLYCOPROTEIN RECEPTOR; CELL DIFFERENTIATION; CELLS, CULTURED; FETAL STEM CELLS; GENES, VIRAL; HEPATITIS B VIRUS; HEPATOCYTES; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, BIOLOGICAL; UMBILICAL CORD; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84872139932     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26006     Document Type: Article

References (33)

1. Quasdorff M, Protzer U. Control of hepatitis B virus at the level of transcription. J Viral Hep 2010; 17: 527-536.
2. Tang H, McLachlan A. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism. Proc Natl Acad Sci U S A 2001; 98: 1841-1846.
3. Quasdorff M, Hösel M, Odenthal M, Zedler U, Bohne F, Gripon P, et al. A concerted action of HNF4α and HNF1α links hepatitis B virus replication to hepatocyte differentiation. Cell Microbiol 2008; 10: 1478-1490.
4. Sells MA, Zelent AZ, Shvartsman M, Acs G. Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions. J Virol 1988; 62: 2836-2844.
5. Sun D, Nassal M. Stable HepG2- and Huh7-based human hepatoma cell lines for efficient regulated expression of infectious hepatitis B virus. J Hepatol 2006; 45: 636-645.
6. Rabe B, Glebe D, Kann M. Lipid-mediated introduction of hepatitis B virus capsids into nonsusceptible cells allows highly efficient replication and facilitates the study of early infection events. J Virol 2006; 80: 5465-5473.
7. Glebe D, Urban S. Viral and cellular determinants involved in hepadnaviral entry. World J Gastroenterol 2007; 13: 22-38.
8. Treichel U, Meyer zum Büschenfelde KH, Stockert RJ, Poralla T, Gerken G. The asialoglycoprotein receptor mediates hepatic binding and uptake of natural hepatitis B virus particles derived from viraemic carriers. J Gen Virol 1994; 75: 3021-3029.
9. Owada T, Matsubayashi H, Sakata H, Ihara S, Sato K, Ikebuchi et al. Interaction between desialylated hepatitis B virus and asialoglycoprotein receptor on hepatocytes may be indispensable for viral binding and entry. J Viral Hepat 2006; 13: 11-18.
10. Yang J, Bo XC, Ding XR, Dai JM, Zhang ML, Wang XH, et al. Antisense oligonucleotides targeted against asialoglycoprotein receptor 1 block human hepatitis B virus replication. J Viral Hepat 2006; 13: 158-165.
11. Mabit H, Vons C, Dubanchet S, Capel F, Franco D, Petit MA. Primary cultured normal human hepatocytes for hepatitis B virus receptor studies. J Hepatol 1996; 24: 403-412.
12. Walter E, Keist R, Niederöst B, Pult I, Blum HE. Hepatitis B virus infection of tupaia hepatocytes in vitro and in vivo. Hepatology 1996; 24: 1-5.
13. Köck J, Nassal M, MacNelly S, Baumert TF, Blum HE, Weizsäcker von F. Efficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virus. J Virol 2001; 75: 5084-5089.
14. Gripon P, Rumin S, Urban S, Le Seyec J, Glaise D, Cannie I, et al. Infection of a human hepatoma cell line by hepatitis B virus. Proc Natl Acad Sci U S A 2002; 99: 15655-15660.
15. Najimi M, Khuu DN, Lysy PA, Jazouli N, Abarca J, Sempoux C, et al. Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes? Cell Transplant 2007; 16: 717-728.
16. Campard D, Lysy PA, Najimi M, Sokal EM. Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells. Gastroenterology 2008; 134: 833-848.
17. Lysy PA, Smets F, Sibille C, Najimi M, Sokal EM. Human skin fibroblasts: From mesodermal to hepatocyte-like differentiation. Hepatology 2007; 46: 1574-1585.
18. Sokal EM, Smets F, Bourgois A, van Maldergem L, Buts J-P, Reding R, et al. Hepatocyte transplantation in a 4-year-old girl with peroxisomal biogenesis disease: technique, safety, and metabolic follow-up. Transplantation 2003; 76: 735-738.
19. Ladner SK, Otto MJ, Barker CS, Zaifert K, Wang GH, Guo JT, et al. Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication. Antimicrob Agents Chemother 1997; 41: 1715-1720.
20. Gripon P, Diot C, Guguen-Guillouzo C. Reproducible high level infection of cultured adult human hepatocytes by hepatitis B virus: effect of polyethylene glycol on adsorption and penetration. Virology 1993; 192: 534-540.
21. Saunier B, Triyatni M, Ulianich L, Maruvada P, Yen P, Kohn LD. Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes. J Virol 2003; 77: 546-559.
22. Offensperger WB, Offensperger S, Walter E, Blum HE, Gerok W. Suramin prevents duck hepatitis B virus infection in vivo. Antimicrob Agents Chemother 1993; 37: 1539-1542.
23. Schulze A, Gripon P, Urban S. Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans. Hepatology 2007; 46: 1759-1768.
24. Werle-Lapostolle B, Bowden S, Locarnini S, Wursthorn K, Petersen J, Lau G, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004; 126: 1750-1758.
25. Ying C, de Clercq E, Nicholson W, Furman P, Neyts J. Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir. J Viral Hepat 2000; 7: 161-165.
26. Leistner CM, Gruen-Bernhard S, Glebe D. Role of glycosaminoglycans for binding and infection of hepatitis B virus. Cell Microbiol 2008; 10: 122-133.
27. Spiess M. The asialoglycoprotein receptor: a model for endocytic transport receptors. Biochemistry 1990; 29: 10009-10018.
28. Rong Q, Zhang L, Su E, Li J, Liu Z, Huang Z, et al. Bone marrow-derived mesenchymal stem cells are capable of mediating hepatitis B virus infection in injured tissues. J Viral Hepat 2008; 15: 607-614.
29. Xie C, Zheng Y-B, Zhu H-P, Peng L, Gao Z-L. Human bone marrow mesenchymal stem cells are resistant to HBV infection during differentiation into hepatocytes in vivo and in vitro. Cell Biol Int 2009; 33: 493-500.
30. Elaut G, Henkens T, Papeleu P, Snykers S, Vinken M, Vanhaecke T, et al. Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. Curr Drug Metab 2006; 7: 629-660.
31. Schulze A, Mills K, Weiss TS, Urban S. Hepatocyte polarization is essential for the productive entry of the hepatitis B virus. Hepatology 2012; 55: 373-383.
32. Basma H, Soto-Gutiérrez A, Yannam GR, Liu L, Ito R, Yamamoto T, et al. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology 2009; 136: 990-999.
33. Ochiya T, Tsurimoto T, Ueda K, Okubo K, Shiozawa M, Matsubara K. An in vitro system for infection with hepatitis B virus that uses primary human fetal hepatocytes. Proc Natl Acad Sci U S A 1989; 86: 1875-1879.