A reliable synthesis of 3-amino-5-alkyl and 5-amino-3-alkyl isoxazoles

Synthesis (Germany)

Volumn 45, Issue 2, 2013, Pages 171-173

  Johnson, Leland ^a   Powers, James ^a   Ma, Fupeng ^a   Jendza, Keith ^a   Wang, Bing ^a   Meredith, Erik ^a   Mainolfi, Nello ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

condensation; heterocycles; imines; medicinal chemistry; regioselectivity

Indexed keywords

HETEROCYCLES; IMINES; ISOXAZOLES; MEDICINAL CHEMISTRY; REACTION TEMPERATURE;

CHEMISTRY; CONDENSATION; SPEECH SYNTHESIS;

REGIOSELECTIVITY;

3 (1 METHYLCYCLOPROPYL)ISOXAZOL 5 YLAMINE; 3 ISOPROPYLISOXAZOL 5 YLAMINE; 3 OXO 3 [1 (TRIFLUOROMETHYL)CYCLOPROPYL]PROPANENITRILE; 5 (1 METHYLCYCLOPROPYL)ISOXAZOL 3 YLAMINE; 5 [1 (TRIFLUOROMETHYL)CYCLOPROPYL]ISOXAZOL 3 AMINE; 5 CYCLOBUTYLISOXAZOL 3 YLAMINE; 5 CYCLOPROPYLISOXAZOL 3 YLAMINE; 5 ISOBUTYLISOXAZOL 3 YLAMINE; 5 ISOPROPYLISOXAZOL 3 YLAMINE; ISOXAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; ISOMERISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; REACTION ANALYSIS; TEMPERATURE SENSITIVITY;

EID: 84872107425     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0032-1317935     Document Type: Article

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