Control of three-dimensional substrate stiffness to manipulate mesenchymal stem cell fate toward neuronal or glial lineages

Acta Biomaterialia

Volumn 9, Issue 2, 2013, Pages 5170-5180

  Her, Goh Jih ^a   Wu, Hsi Chin ^b   Chen, Ming Hong ^a,c   Chen, Ming Yi ^d   Chang, Shun Chih ^d   Wang, Tzu Wei ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b TATUNG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

3 D scaffold; Mechanical property; Mesenchymal stem cell; Nerve tissue engineering; Substrate stiffness

Indexed keywords

BIOMECHANICS; BIOMIMETICS; CELL ENGINEERING; CELL SIGNALING; CROSSLINKING; ENZYME ACTIVITY; HYALURONIC ACID; NEURONS; SCAFFOLDS (BIOLOGY); STEM CELLS; STIFFNESS; STIFFNESS MATRIX; SUBSTRATES; TISSUE;

3D SCAFFOLDS; CELL-FATE; HUMAN MESENCHYMAL STEM CELLS; MATRIX; MESENCHYMAL STEM CELL; NERVE TISSUE ENGINEERING; SELF RENEWAL; STEM-CELL; SUBSTRATE STIFFNESS; THREE-DIMENSIONAL SUBSTRATES;

CELL CULTURE;

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; COLLAGEN TYPE 1; HYALURONIC ACID; MOLECULAR SCAFFOLD;

ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL MANIPULATION; CELL MEMBRANE; CELL PROLIFERATION; CELL RENEWAL; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CROSS LINKING; GLIA CELL; MESENCHYMAL STEM CELL; MOLECULAR SIZE; NERVE CELL; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIGIDITY; YOUNG MODULUS;

EID: 84872073873     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.10.012     Document Type: Article

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