Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis.

PloS one

Volumn 7, Issue 11, 2012, Pages

  Puri, Sumant ^a   Kumar, Rohitashw ^b   Chadha, Sonia ^b   Tati, Swetha ^b   Conti, Heather R ^b   Hube, Bernhard ^b   Cullen, Paul J ^b   Edgerton, Mira ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; BETA GLUCAN; CEK1 PROTEIN, CANDIDA ALBICANS; FUNGAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPSTATIN;

ANIMAL; ARTICLE; BIOFILM; BIOLOGICAL MODEL; CANDIDA ALBICANS; CANDIDIASIS; CELL MEMBRANE; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; ENVIRONMENT; ENZYME ACTIVATION; ENZYMOLOGY; FUNGUS HYPHAE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; MOUSE; MOUTH DISEASE; MUTATION; PATHOLOGY; PHARYNX DISEASE; PHOSPHORYLATION; PHYSIOLOGY; PLANKTON; PROTEIN DEGRADATION; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

ANIMALS; ASPARTIC ACID PROTEASES; BETA-GLUCANS; BIOFILMS; CANDIDA ALBICANS; CANDIDIASIS; CELL MEMBRANE; CULTURE MEDIA; ENVIRONMENT; ENZYME ACTIVATION; FUNGAL PROTEINS; HYPHAE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; MOUTH DISEASES; MUTATION; PEPSTATINS; PHARYNGEAL DISEASES; PHOSPHORYLATION; PLANKTON; PROTEOLYSIS;

EID: 84872050716     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046020     Document Type: Article

References (0)