The utility of lung epithelium specific biomarkers in cardiac surgery: A comparison of biomarker profiles in on- and off-pump coronary bypass surgery

Journal of Cardiothoracic Surgery

Volumn 8, Issue 1, 2013, Pages

  Engels, Gerwin E ^a   Gu, Y John ^b   van Oeveren, Willem ^a,b   Rakhorst, Gerhard ^b   Mariani, Massimo A ^b   Erasmus, Michiel E ^b  

^a HaemoScan   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

CABG; Cardiopulmonary bypass; Clara cell 16 kD protein; Off pump; Surfactant protein D

Indexed keywords

BIOLOGICAL MARKER; OXYGEN; PANCREATIC ELASTASE; PEROXIDASE; SCGB1A1 PROTEIN, HUMAN; SURFACTANT PROTEIN D; UTEROGLOBIN;

AGED; ANALYSIS OF VARIANCE; ARTICLE; BLOOD; CARDIOPULMONARY BYPASS; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; FEMALE; HUMAN; LUNG; LUNG FUNCTION TEST; LUNG INJURY; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; OXIMETRY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT MUCOSA;

AGED; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CARDIOPULMONARY BYPASS; CORONARY ARTERY BYPASS; FEMALE; HUMANS; LUNG; LUNG INJURY; MALE; MIDDLE AGED; OXIMETRY; OXYGEN; PANCREATIC ELASTASE; PEROXIDASE; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; RESPIRATORY FUNCTION TESTS; RESPIRATORY MUCOSA; UTEROGLOBIN;

MLCS; MLOWN;

EID: 84872016885     PISSN: None     EISSN: 17498090     Source Type: Journal    
DOI: 10.1186/1749-8090-8-4     Document Type: Article

References (28)

1. Ng CSH, Wan S, Yim APC, Arifi AA. Pulmonary dysfunction after cardiac surgery. Chest 2002, 121:1269-1277. 10.1378/chest.121.4.1269, 11948063.
2. Wan S, LeClerc J-L, Vincent J-L. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest 1997, 112:676-692. 10.1378/chest.112.3.676, 9315800.
3. Hermans C, Bernard A. Lung epithelium-specific proteins: characteristics and potential applications as markers. Am J Respir Crit Care Med 1999, 159:646-678.
4. Sorensen GL, Husby S, Holmskov U. Surfactant protein A and surfactant protein D variation in pulmonary disease. Immunobiology 2007, 212:381-416. 10.1016/j.imbio.2007.01.003, 17544823.
5. Agostoni P, Banfi C, Brioschi M, Magrì D, Sciomer S, Berna G, et al. Surfactant protein B and RAGE increases in the plasma during cardiopulmonary bypass: a pilot study. Eur Respir J 2011, 37:841-847. 10.1183/09031936.00045910, 20650982.
6. Pilette C, Godding V, Kiss R, Delos M, Verbeken E, Decaestecker C, et al. Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001, 163:185-194.
7. Diamond JM, Kawut SM, Lederer DJ, Ahya VN, Kohl B, Sonett J, et al. Elevated plasma clara cell secretory protein concentration is associated with high-grade primary graft dysfunction. Am J Transplant 2011, 11:561-567. 10.1111/j.1600-6143.2010.03431.x, 3079443, 21299834.
8. Determann RM, Millo JL, Waddy S, Lutter R, Garrard CS, Schultz MJ. Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study. BMC Pulm Med 2009, 9:49. 10.1186/1471-2466-9-49, 2794841, 19958527.
9. e Silva AMRP, Saad R, Stirbulov R, Rivetti LA. Off-pump versus on-pump coronary artery revascularization: effects on pulmonary function. Interact Cardiovasc Thorac Surg 2010, 11:42-45. 10.1510/icvts.2009.229617, 20403972.
10. Gu YJ, Graaff R, de Hoog E, Veeger NJGM, Panday G, Boonstra PW, et al. Influence of hemodilution of plasma proteins on erythrocyte aggregability: an in vivo study in patients undergoing cardiopulmonary bypass. Clin Hemorheol Microcirc 2005, 33:95-107.
11. van Boven W-JP, Gerritsen WBM, Zanen P, Grutters JC, van Dongen HPA, Bernard A, et al. Pneumoproteins as a lung-specific biomarker of alveolar permeability in conventional on-pump coronary artery bypass graft surgery vs mini-extracorporeal circuit: a pilot study. Chest 2005, 127:1190-1195. 10.1378/chest.127.4.1190, 15821194.
12. Lakind JS, Holgate ST, Ownby DR, Mansur AH, Helms PJ, Pyatt D, et al. A critical review of the use of clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects. Biomarkers 2007, 12:445-467. 10.1080/13547500701359327, 17701745.
13. Miller BE, Levy JH. The inflammatory response to cardiopulmonary bypass. J Cardiothorac Vasc Anesth 1997, 11:355-366. 10.1016/S1053-0770(97)90106-3, 9161905.
14. Ginzberg HH, Cherapanov V, Dong Q, Cantin A, McCulloch CA, Shannon PT, et al. Neutrophil-mediated epithelial injury during transmigration: role of elastase. Am J Physiol Gastrointest Liver Physiol 2001, 281:G705-G717.
15. Arnhold J, Flemmig J. Human myeloperoxidase in innate and acquired immunity. Arch Biochem Biophys 2010, 500:92-106. 10.1016/j.abb.2010.04.008, 20399194.
16. Usatyuk PV, Natarajan V. Regulation of reactive oxygen species-induced endothelial cell-cell and cell-matrix contacts by focal adhesion kinase and adherens junction proteins. Am J Physiol Lung Cell Mol Physiol 2005, 289:L999-L1010. 10.1152/ajplung.00211.2005, 16040628.
17. Friedrich B, Schmidt R, Reiss I, Günther A, Seeger W, Müller M, et al. Changes in biochemical and biophysical surfactant properties with cardiopulmonary bypass in children. Crit Care Med 2003, 31:284-290. 10.1097/00003246-200301000-00045, 12545030.
18. Determann RM, Wolthuis EK, Choi G, Bresser P, Bernard A, Lutter R, et al. Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury. Am J Physiol Lung Cell Mol Physio 2008, 294:L344-L350.
19. Elmistekawy E, Chan V, Bourke ME, Dupuis J-Y, Rubens FD, Mesana TG, et al. Off-pump coronary artery bypass grafting does not preserve renal function better than on-pump coronary artery bypass grafting: results of a case-matched study. J Thorac Cardiovasc Surg 2012, 143:85-92. 10.1016/j.jtcvs.2011.09.035, 22036259.
20. Nesher N, Frolkis I, Vardi M, Sheinberg N, Bakir I, Caselman F, et al. Higher levels of serum cytokines and myocardial tissue markers during on-pump versus off-pump coronary artery bypass surgery. J Card Surg 2006, 21:395-402. 10.1111/j.1540-8191.2006.00272.x, 16846420.
21. Greilich PE, Brouse CF, Rinder HM, Jessen ME, Rinder CS, Eberhart RC, et al. Monocyte activation in on-pump versus off-pump coronary artery bypass surgery. J Cardiothorac Vasc Anesth 2008, 22:361-368. 10.1053/j.jvca.2007.08.009, 18503922.
22. Staton GW, Williams WH, Mahoney EM, Hu J, Chu H, Duke PG, et al. Pulmonary outcomes of off-pump vs on-pump coronary artery bypass surgery in a randomized trial. Chest 2005, 127:892-901. 10.1378/chest.127.3.892, 15764773.
23. Groeneveld ABJ, Jansen EK, Verheij J. Mechanisms of pulmonary dysfunction after on-pump and off-pump cardiac surgery: a prospective cohort study. J Cardiothorac Surg 2007, 2:11. 10.1186/1749-8090-2-11, 1802750, 17300720.
24. Montes FR, Maldonado JD, Paez S, Ariza F. Off-pump versus on-pump coronary artery bypass surgery and postoperative pulmonary dysfunction. J Cardiothorac Vasc Anesth 2004, 18:698-703. 10.1053/j.jvca.2004.08.004, 15650976.
25. Cimen S, Ozkul V, Ketenci B, Yurtseven N, Günay R, Ketenci B, et al. Daily comparison of respiratory functions between on-pump and off-pump patients undergoing CABG. Eur J Cardiothorac Surg 2003, 23:589-594. 10.1016/S1010-7940(03)00023-X, 12694781.
26. Kerendi F, Halkos ME, Puskas JD, Lattouf OM, Kilgo P, Guyton RA, et al. Impact of off-pump coronary artery bypass graft surgery on postoperative pulmonary complications in patients with chronic lung disease. Ann Thorac Surg 2011, 91:8-15. 10.1016/j.athoracsur.2010.08.003, 21172475.
27. Quaniers JM, Leruth J, Albert A, Limet RR, Defraigne J-O. Comparison of inflammatory responses after off-pump and on-pump coronary surgery using surface modifying additives circuit. Ann Thorac Surg 2006, 81:1683-1690. 10.1016/j.athoracsur.2005.11.059, 16631656.
28. Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, et al. Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase. Circulation 2006, 113:1871-1878. 10.1161/CIRCULATIONAHA.105.590083, 16606792.