The riddle of protein diagnostics: Future bleak or bright?

Clinical Chemistry

Volumn 59, Issue 1, 2013, Pages 194-197

  Anderson, N Leigh ^a   Ptolemy, Adam S ^b,c   Rifai, Nader ^c,d  

^a The Plasma Proteome Institute   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

ACCURACY; CANCER DIAGNOSIS; CANCER PATIENT; HUMAN; MOLECULAR DIAGNOSTICS; NOTE; VALIDITY;

HUMANS; NEOPLASMS; PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 84872008110     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2012.184705     Document Type: Note

References (6)

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2. Ptolemy AS, Rifai N. What is a biomarker? Research investments and lack of clinical integration necessitate a review of biomarker terminology and validation schema. Scand J Clin Lab Invest 2010;70:6-14.
3. NIH Research Portfolio Online Reporting Tools (RePORT). http://report.nih.gov/ (Accessed June 2012).
4. Lee BTK, Liew L, Lim J, Tan JKL, Lee TC, Veladandi PS, et al. Candidate List of yoUr Biomarker (CLUB): a web-based platform to aid cancer biomarker research. Biomark Insights 2008;3:65-71. (Pubitemid 351279847)
5. Rifai N, Gillette MA, Carr SA. Protein biomarker discovery and validation: the long and uncertain path to clinical utility. Nat Biotechnol 2006;24:971-83. (Pubitemid 44215392)
6. Anderson, L. Within sight of a rational pipeline for development of protein diagnostics. Clin Chem 2011;58:28-30.