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Volumn 17, Issue 7 PARTB, 2012, Pages 1415-1422

The challenges of hepatitis C diagnosis and the potential role of Stimmunology™ to address them

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY; VIRUS ANTIGEN;

EID: 84872000450     PISSN: 13596535     EISSN: 20402058     Source Type: Journal    
DOI: 10.3851/IMP2472     Document Type: Review
Times cited : (2)

References (50)
  • 1
    • 84871950595 scopus 로고    scopus 로고
    • Updated 12 April Accessed 5 September 2012. Available from
    • Centers for Disease Control and Prevention. Sexually transmitted diseases; treatment guidelines 2006, hepatitis C. (Updated 12 April 2007. Accessed 5 September 2012.) Available from http://www.cdc.gov/std/treatment/ 2006/hepatitis-c.htm
    • (2007) Sexually Transmitted Diseases; Treatment Guidelines 2006, Hepatitis C
  • 2
    • 23944467250 scopus 로고    scopus 로고
    • Adaptive immune responses in acute and chronic hepatitis C virus infection
    • Bowen DG, Walker CM. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005; 436:946-952.
    • (2005) Nature , vol.436 , pp. 946-952
    • Bowen, D.G.1    Walker, C.M.2
  • 3
    • 15744380197 scopus 로고    scopus 로고
    • Acute-phase hepatitis C virus infection: Implications for research, diagnosis, and treatment
    • Busch MP, Shafer KA. Acute-phase hepatitis C virus infection: implications for research, diagnosis, and treatment. Clin Infect Dis 2005; 40:959-961.
    • (2005) Clin Infect Dis , vol.40 , pp. 959-961
    • Busch, M.P.1    Shafer, K.A.2
  • 4
    • 80051701851 scopus 로고    scopus 로고
    • World Hepatitis Day: A new era for hepatitis control
    • Ward JW, Averhoff FM, Koh HK. World Hepatitis Day: a new era for hepatitis control. Lancet 2011; 378:552-553.
    • (2011) Lancet , vol.378 , pp. 552-553
    • Ward, J.W.1    Averhoff, F.M.2    Koh, H.K.3
  • 5
    • 84871978555 scopus 로고    scopus 로고
    • (Accessed 13 September 2012.) Available from
    • CDC Viral Hepatitis - HCV Symposium, December 2011. (Accessed 13 September 2012.) Available from http://www.cdc.gov/hepatitis/Resources/MtgsConf/ HCVSymposium2011.htm
    • CDC Viral Hepatitis - HCV Symposium, December 2011
  • 6
    • 80054074091 scopus 로고    scopus 로고
    • World Hepatitis Day to tackle viral hepatitis
    • Burki T. World Hepatitis Day to tackle viral hepatitis. Lancet Infect Dis 2011; 11:589-590.
    • (2011) Lancet Infect Dis , vol.11 , pp. 589-590
    • Burki, T.1
  • 7
    • 4143071570 scopus 로고    scopus 로고
    • Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing
    • Stramer SL, Glynn SA, Kleinman SH, et al. Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing. N Engl J Med 2004; 351:760-768.
    • (2004) N Engl J Med , vol.351 , pp. 760-768
    • Stramer, S.L.1    Glynn, S.A.2    Kleinman, S.H.3
  • 8
    • 33645217688 scopus 로고    scopus 로고
    • Estimates of the frequency of HBV, HCV, and HIV infectious donations entering the blood supply in the United Kingdom, 1996 to 2003
    • Soldan K, Davison K, Dow B. Estimates of the frequency of HBV, HCV, and HIV infectious donations entering the blood supply in the United Kingdom, 1996 to 2003. Euro Surveill 2005; 10:17-19.
    • (2005) Euro Surveill , vol.10 , pp. 17-19
    • Soldan, K.1    Davison, K.2    Dow, B.3
  • 9
    • 33845896269 scopus 로고    scopus 로고
    • Impaired hepatitis C virus-specific T-cell responses and recurrent hepatitis C virus in HIV coinfection
    • Kim AY, Schulze zur Wiesch J, Kuntzen T, et al. Impaired hepatitis C virus-specific T-cell responses and recurrent hepatitis C virus in HIV coinfection. PLoS Med 2006; 3:e492.
    • (2006) PLoS Med , vol.3
    • Kim, A.Y.1    Schulze Zur Wiesch, J.2    Kuntzen, T.3
  • 10
    • 10044230829 scopus 로고    scopus 로고
    • Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in China
    • Zhang L, Chen Z, Cao Y, et al. Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in China. J Virol 2004; 78:13591-13599.
    • (2004) J Virol , vol.78 , pp. 13591-13599
    • Zhang, L.1    Chen, Z.2    Cao, Y.3
  • 11
    • 55449083234 scopus 로고    scopus 로고
    • Hepatitis C virus infection in Guinea-Bissau: A sexually transmitted genotype 2 with parenteral amplification?
    • Plamondon M, Labbé AC, Frost E, et al. Hepatitis C virus infection in Guinea-Bissau: a sexually transmitted genotype 2 with parenteral amplification? PLoS ONE 2007; 2:e372.
    • (2007) PLoS ONE , vol.2
    • Plamondon, M.1    Labbé, A.C.2    Frost, E.3
  • 12
    • 0012539580 scopus 로고    scopus 로고
    • (Updated 13 August 2012. Accessed 5 September 2012.) Available from
    • CDC. Sexually transmitted diseases treatment guidelines, 2010. (Updated 13 August 2012. Accessed 5 September 2012.) Available from http://www.cdc.gov/ std/treatment/2010/
    • (2010) Sexually Transmitted Diseases Treatment Guidelines
  • 13
    • 84855244456 scopus 로고    scopus 로고
    • Boceprevir and telaprevir for the treatment of chronic hepatitis C: Safety management in clinical practice
    • Hézode C. Boceprevir and telaprevir for the treatment of chronic hepatitis C: safety management in clinical practice. Liver Int 2012; 32 Suppl 1:32-38.
    • (2012) Liver Int , vol.32 , Issue.SUPPL. 1 , pp. 32-38
    • Hézode, C.1
  • 14
    • 84871972555 scopus 로고    scopus 로고
    • Two protease inhibitors for HCV. Victrelis, Incivek
    • Two protease inhibitors for HCV. Victrelis, Incivek. Pharmacy and Therapeutics 2011; 36:320-331.
    • (2011) Pharmacy and Therapeutics , vol.36 , pp. 320-331
  • 15
    • 84857474172 scopus 로고    scopus 로고
    • A viral dynamic model for treatment regimens with direct-acting antivirals for chronic hepatitis C infection
    • Adiwijaya BS, Kieffer TL, Henshaw J, et al. A viral dynamic model for treatment regimens with direct-acting antivirals for chronic hepatitis C infection. PLoS Comput Biol 2012; 8:e1002339.
    • (2012) PLoS Comput Biol , vol.8
    • Adiwijaya, B.S.1    Kieffer, T.L.2    Henshaw, J.3
  • 16
    • 80051687993 scopus 로고    scopus 로고
    • New hepatitis C therapies in clinical development
    • Vermehren J, Sarrazin C. New hepatitis C therapies in clinical development. Eur J Med Res 2011; 16:303-314.
    • (2011) Eur J Med Res , vol.16 , pp. 303-314
    • Vermehren, J.1    Sarrazin, C.2
  • 18
    • 33646895462 scopus 로고    scopus 로고
    • Efficacy of early treatment of acute hepatitis C infection with pegylated interferon and ribavirin in HIV-infected patients
    • Dominguez S, Ghosn J, Valantin MA, et al. Efficacy of early treatment of acute hepatitis C infection with pegylated interferon and ribavirin in HIV-infected patients. AIDS 2006; 20:1157-1161.
    • (2006) AIDS , vol.20 , pp. 1157-1161
    • Dominguez, S.1    Ghosn, J.2    Valantin, M.A.3
  • 19
    • 3142723140 scopus 로고    scopus 로고
    • Treatment of acute hepatitis C with interferon alpha-2b: Early initiation of treatment is the most effective predictive factor of sustained viral response
    • Delwaide J, Bourgeois N, Gérard C, et al. Treatment of acute hepatitis C with interferon alpha-2b: early initiation of treatment is the most effective predictive factor of sustained viral response. Aliment Pharmacol Ther 2004; 20:15-22.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 15-22
    • Delwaide, J.1    Bourgeois, N.2    Gérard, C.3
  • 20
    • 0032538246 scopus 로고    scopus 로고
    • Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease
    • CDC
    • CDC. Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease. MMWR Recomm Rep 1998; 47 RR-19:1-39.
    • (1998) MMWR Recomm Rep , vol.47 , Issue.RR-19 , pp. 1-39
  • 21
    • 84871971117 scopus 로고    scopus 로고
    • CDC releases revised HIV testing recommendations in healthcare settings
    • Updated September Accessed 5 September 2012. Available from
    • CDC HIV/AIDS Science Facts. CDC releases revised HIV testing recommendations in healthcare settings. (Updated September 2006. Accessed 5 September 2012.) Available from http://www.cdc.gov/hiv/topics/testing/resources/ factsheets/pdf/healthcare.pdf
    • (2006) CDC HIV/AIDS Science Facts
  • 22
    • 66249106683 scopus 로고    scopus 로고
    • Long-term effectiveness and cost-effectiveness of screening for hepatitis C virus infection
    • Sroczynski G, Esteban E, Conrads-Frank A, et al. Long-term effectiveness and cost-effectiveness of screening for hepatitis C virus infection. Eur J Public Health 2009; 19:245-253.
    • (2009) Eur J Public Health , vol.19 , pp. 245-253
    • Sroczynski, G.1    Esteban, E.2    Conrads-Frank, A.3
  • 23
    • 84871980606 scopus 로고    scopus 로고
    • (Accessed 6 September 2007.) Available from
    • WHO. Hepatitis C virus. (Accessed 6 September 2007.) Available from http://www.who.int/vaccine-research/diseases/viral-cancers/en/index2.html
    • Hepatitis C Virus
  • 24
    • 0002619532 scopus 로고
    • Analysis of the role of hepatitis C virus in transfusion associated hepatitis
    • Hollinger FB, Margolis H (Editors). Baltimore: Williams & Williams
    • Alter H, Jett B, Polito A. Analysis of the role of hepatitis C virus in transfusion associated hepatitis. In Hollinger FB, Margolis H (Editors). Viral hepatitis and liver disease. Baltimore: Williams & Williams 1991; pp. 396-402.
    • (1991) Viral Hepatitis and Liver Disease , pp. 396-402
    • Alter, H.1    Jett, B.2    Polito, A.3
  • 25
    • 1942435217 scopus 로고    scopus 로고
    • First report of human immunodeficiency virus transmission via an RNA-screened blood donation
    • Delwart EL, Kalmin ND, Jones TS, et al. First report of human immunodeficiency virus transmission via an RNA-screened blood donation. Vox Sang 2004; 86:171-177.
    • (2004) Vox Sang , vol.86 , pp. 171-177
    • Delwart, E.L.1    Kalmin, N.D.2    Jones, T.S.3
  • 26
    • 0036652785 scopus 로고    scopus 로고
    • Yield of HCV and HIV-1 NAT after screening of 3.6 million blood donations in central Europe
    • Roth WK, Weber M, Buhr S, et al. Yield of HCV and HIV-1 NAT after screening of 3.6 million blood donations in central Europe. Transfusion 2002; 42:862-868.
    • (2002) Transfusion , vol.42 , pp. 862-868
    • Roth, W.K.1    Weber, M.2    Buhr, S.3
  • 27
    • 34247373550 scopus 로고    scopus 로고
    • First case of hepatitis C virus transmission by a red blood cell concentrate after introduction of nucleic acid amplification technique screening in Germany: A comparative study with various assays
    • Kretzschmar E, Chudy M, Nübling CM, et al. First case of hepatitis C virus transmission by a red blood cell concentrate after introduction of nucleic acid amplification technique screening in Germany: a comparative study with various assays. Vox Sang 2007; 92:297-301.
    • (2007) Vox Sang , vol.92 , pp. 297-301
    • Kretzschmar, E.1    Chudy, M.2    Nübling, C.M.3
  • 28
    • 0036246184 scopus 로고    scopus 로고
    • Significant closure of the human immunodeficiency virus type 1 and hepatitis C virus preseroconversion detection windows with a transcription-mediated-amplification-driven assay
    • Kolk DP, Dockter J, Linnen J, et al. Significant closure of the human immunodeficiency virus type 1 and hepatitis C virus preseroconversion detection windows with a transcription-mediated-amplification-driven assay. J Clin Microbiol 2002; 40:1761-1766.
    • (2002) J Clin Microbiol , vol.40 , pp. 1761-1766
    • Kolk, D.P.1    Dockter, J.2    Linnen, J.3
  • 29
    • 0034823832 scopus 로고    scopus 로고
    • Novel approach to reduce the hepatitis C virus (HCV) window period: Clinical evaluation of a new enzyme-linked immunosorbent assay for HCV core antigen
    • Icardi G, Ansaldi F, Bruzzone BM, et al. Novel approach to reduce the hepatitis C virus (HCV) window period: clinical evaluation of a new enzyme-linked immunosorbent assay for HCV core antigen. J Clin Microbiol 2001; 39:3110-3114.
    • (2001) J Clin Microbiol , vol.39 , pp. 3110-3114
    • Icardi, G.1    Ansaldi, F.2    Bruzzone, B.M.3
  • 30
    • 41949121712 scopus 로고    scopus 로고
    • Diagnostic utility of hepatitis C virus core antigen in hemodialysis patients
    • Medhi S, Potukuchi SK, Polipalli SK, et al. Diagnostic utility of hepatitis C virus core antigen in hemodialysis patients. Clin Biochem 2008; 41:447-452.
    • (2008) Clin Biochem , vol.41 , pp. 447-452
    • Medhi, S.1    Potukuchi, S.K.2    Polipalli, S.K.3
  • 31
    • 23844449379 scopus 로고    scopus 로고
    • Humoral immune response in acute hepatitis C virus infection
    • Netski DM, Mosbruger T, Depla E, et al. Humoral immune response in acute hepatitis C virus infection. Clin Infect Dis 2005; 41:667-675.
    • (2005) Clin Infect Dis , vol.41 , pp. 667-675
    • Netski, D.M.1    Mosbruger, T.2    Depla, E.3
  • 32
    • 79955040575 scopus 로고    scopus 로고
    • Novel evolved immunoglobulin (Ig)-binding molecules enhance the detection of IgM against hepatitis C virus
    • Cao J, Chen Q, Zhang H, et al. Novel evolved immunoglobulin (Ig)-binding molecules enhance the detection of IgM against hepatitis C virus. PLoS ONE 2011; 6:e18477.
    • (2011) PLoS ONE , vol.6
    • Cao, J.1    Chen, Q.2    Zhang, H.3
  • 33
    • 0035957964 scopus 로고    scopus 로고
    • Recommendations for preventing transmission of infections among chronic hemodialysis patients
    • CDC. Hemodialysis and Viral Hepatitis. Hepatitis C Testing. Centers for Disease Control and Prevention
    • CDC. Hemodialysis and Viral Hepatitis. Hepatitis C Testing. Centers for Disease Control and Prevention. Recommendations for preventing transmission of infections among chronic hemodialysis patients. MMWR Recomm Rep 2001; 50 RR-5:1-63.
    • (2001) MMWR Recomm Rep , vol.50 , Issue.RR-5 , pp. 1-63
  • 34
    • 57249086419 scopus 로고    scopus 로고
    • Very low hepatitis C antibody levels predict false-positive results and avoid supplemental testing
    • Contreras AM, Tornero-Romo CM, Toribio JG, et al. Very low hepatitis C antibody levels predict false-positive results and avoid supplemental testing. Transfusion 2008; 48:2540-2548.
    • (2008) Transfusion , vol.48 , pp. 2540-2548
    • Contreras, A.M.1    Tornero-Romo, C.M.2    Toribio, J.G.3
  • 35
    • 34249286242 scopus 로고    scopus 로고
    • Evaluation of the Ortho-Clinical Diagnostics Vitros ECi Anti-HCV test: Comparison with three other methods
    • Watterson JM, Stallcup P, Escamilla D, Chernay P, Reyes A, Trevino SC. Evaluation of the Ortho-Clinical Diagnostics Vitros ECi Anti-HCV test: comparison with three other methods. J Clin Lab Anal 2007; 21:162-166.
    • (2007) J Clin Lab Anal , vol.21 , pp. 162-166
    • Watterson, J.M.1    Stallcup, P.2    Escamilla, D.3    Chernay, P.4    Reyes, A.5    Trevino, S.C.6
  • 36
    • 63049138955 scopus 로고    scopus 로고
    • Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan
    • Kita M, Deguchi M, Kagita M, et al. Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan. Clin Lab 2009; 55:9-22.
    • (2009) Clin Lab , vol.55 , pp. 9-22
    • Kita, M.1    Deguchi, M.2    Kagita, M.3
  • 37
    • 0038575483 scopus 로고    scopus 로고
    • Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
    • Gerlach JT, Diepolder HM, Zachoval R, et al. Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance. Gastroenterology 2003; 125:80-88.
    • (2003) Gastroenterology , vol.125 , pp. 80-88
    • Gerlach, J.T.1    Diepolder, H.M.2    Zachoval, R.3
  • 38
    • 13844270879 scopus 로고    scopus 로고
    • Efficacy of a 24-week course of PEG-interferon alpha-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance
    • Santantonio T, Fasano M, Sinisi E, et al. Efficacy of a 24-week course of PEG-interferon alpha-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance. J Hepatol 2005; 42:329-333.
    • (2005) J Hepatol , vol.42 , pp. 329-333
    • Santantonio, T.1    Fasano, M.2    Sinisi, E.3
  • 39
    • 20144368978 scopus 로고    scopus 로고
    • Prospective evaluation of community-acquired acute-phase hepatitis C virus infection
    • Cox AL, Netski DM, Mosbruger T, et al. Prospective evaluation of community-acquired acute-phase hepatitis C virus infection. Clin Infect Dis 2005; 40:951-958.
    • (2005) Clin Infect Dis , vol.40 , pp. 951-958
    • Cox, A.L.1    Netski, D.M.2    Mosbruger, T.3
  • 40
    • 0036788580 scopus 로고    scopus 로고
    • Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies
    • Larghi A, Zuin M, Crosignani A, et al. Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies. Hepatology 2002; 36:993-1000.
    • (2002) Hepatology , vol.36 , pp. 993-1000
    • Larghi, A.1    Zuin, M.2    Crosignani, A.3
  • 41
    • 4644229225 scopus 로고    scopus 로고
    • Clearance of hepatitis C virus after newly acquired infection in injection drug users
    • Jauncey M, Micallef J, Gilmour S, et al. Clearance of hepatitis C virus after newly acquired infection in injection drug users. J Infect Dis 2004; 190:1270-1274.
    • (2004) J Infect Dis , vol.190 , pp. 1270-1274
    • Jauncey, M.1    Micallef, J.2    Gilmour, S.3
  • 42
    • 0034030136 scopus 로고    scopus 로고
    • Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
    • Takaki A, Wiese M, Maertens G, et al. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat Med 2000; 6:578-582.
    • (2000) Nat Med , vol.6 , pp. 578-582
    • Takaki, A.1    Wiese, M.2    Maertens, G.3
  • 43
    • 17144417208 scopus 로고    scopus 로고
    • Hepatitis C viral clearance in an intravenous drug-using cohort in the Dublin area
    • Keating S, Coughlan S, Connell J, Sweeney B, Keenan E. Hepatitis C viral clearance in an intravenous drug-using cohort in the Dublin area. Ir J Med Sci 2005; 174:37-41.
    • (2005) Ir J Med Sci , vol.174 , pp. 37-41
    • Keating, S.1    Coughlan, S.2    Connell, J.3    Sweeney, B.4    Keenan, E.5
  • 44
    • 0034046181 scopus 로고    scopus 로고
    • Regulation of antibody responses via antibodies, complement and Fc receptors
    • Heyman B. Regulation of antibody responses via antibodies, complement and Fc receptors. Annu Rev Immunol 2000; 18:709-737.
    • (2000) Annu Rev Immunol , vol.18 , pp. 709-737
    • Heyman, B.1
  • 45
    • 80054910166 scopus 로고    scopus 로고
    • Update on hepatitis C virus-specific immunity
    • Ciuffreda D, Kim AY. Update on hepatitis C virus-specific immunity. Curr Opin HIV AIDS 2011; 6:559-565.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 559-565
    • Ciuffreda, D.1    Kim, A.Y.2
  • 46
    • 84871952314 scopus 로고    scopus 로고
    • The HIV seronegative window period: Diagnostic challenges and solutions
    • Tang Y-W (Editor). Rijeka, Croatia: InTech
    • Jehuda-Cohen T. The HIV seronegative window period: diagnostic challenges and solutions. In Tang Y-W (Editor). Recent translational research in HIV/AIDS. Rijeka, Croatia: InTech 2011; pp. 179-202.
    • (2011) Recent Translational Research in HIV/AIDS , pp. 179-202
    • Jehuda-Cohen, T.1
  • 47
    • 60849085220 scopus 로고    scopus 로고
    • HIV Type 1 infection among Ethiopian immigrants to Israel: Enhanced in vitro antibody stimulation for estimating the length of the window period
    • Novikov I, Jehuda-Cohen T. HIV Type 1 infection among Ethiopian immigrants to Israel: enhanced in vitro antibody stimulation for estimating the length of the window period. AIDS Res Hum Retroviruses 2009; 25:165-174.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , pp. 165-174
    • Novikov, I.1    Jehuda-Cohen, T.2
  • 48
    • 68149175258 scopus 로고    scopus 로고
    • Detecting seronegative-early HIV infections among adult versus student Kenyan blood donors, by using Stimmunology
    • Mumo J, Vansover A, Jehuda-Cohen T. Detecting seronegative-early HIV infections among adult versus student Kenyan blood donors, by using Stimmunology. Exp Biol Med (Maywood) 2009; 234:931-939.
    • (2009) Exp Biol Med (Maywood) , vol.234 , pp. 931-939
    • Mumo, J.1    Vansover, A.2    Jehuda-Cohen, T.3
  • 50
    • 84871966215 scopus 로고    scopus 로고
    • Use of Smartube in determination of antibodies by ELISA method for the diagnosis of HIV and HCV infections
    • Turkish
    • Durmaz N, Sener B, Gumusluoglu B, et al. [Use of Smartube in determination of antibodies by ELISA method for the diagnosis of HIV and HCV infections]. Turk HIV/AIDS Dergisi 2006; 9:112-116. Turkish.
    • (2006) Turk HIV/AIDS Dergisi , vol.9 , pp. 112-116
    • Durmaz, N.1    Sener, B.2    Gumusluoglu, B.3


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