Management and risk factors for mortality in very elderly patients with acute myocardial infarction

Geriatrics and Gerontology International

Volumn 13, Issue 1, 2013, Pages 146-151

  Renilla, Alfredo ^a   Barreiro, Manuel ^a   Barriales, Vicente ^a   Torres, Francisco ^a   Alvarez, Paloma ^a   Lambert, Jose L ^a  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

Author keywords

Aged; Angioplasty; Fibrinolysis; Heart failure; Myocardial infarction

Indexed keywords

AGED; ANGIOPLASTY; ARTICLE; BLEEDING; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; FEMALE; FIBRINOLYSIS; HEART ARRHYTHMIA; HEART FAILURE; HEART MUSCLE REPERFUSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK MANAGEMENT; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; VERY ELDERLY;

AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; COMORBIDITY; FEMALE; HUMANS; MALE; MYOCARDIAL INFARCTION; RISK FACTORS; SPAIN; TREATMENT OUTCOME;

EID: 84871991711     PISSN: 14441586     EISSN: 14470594     Source Type: Journal    
DOI: 10.1111/j.1447-0594.2012.00876.x     Document Type: Article

References (31)

1. Sahyoun NR, Lentzner H, Hoyert D, Robinson KN. Trends in causes of death among the elderly. Aging Trends 2001; 1: 1-10.
2. Alexander KP, Roe MT, Chen AY etal. Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative. J Am Coll Cardiol 2005; 46: 1479-1487.
3. White HD, Barbash GI, Califf RM etal. Age and outcome with contemporary thrombolytic therapy. Results from the GUSTO-I trial. Global Utilization of Streptokinase and TPA for Occluded coronary arteries trial. Circulation 1996; 94: 1826-1833.
4. Yarzebski J, Goldberg RJ, Gore JM, Alpert JS. Temporal trends and factors associated with extent of delay to hospital arrival in patients with acute myocardial infarction: the Worcester Heart Attack Study. Am Heart J 1994; 128: 255-263.
5. Van de Werf F, Bax J, Betriu A etal. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation. Eur Heart J 2008; 29: 2909-2945.
6. Timoteo AT, Ramos R, Toste A etal. Impact of age on treatment and outcomes after acute myocardial infarction, particularly in very elderly patients. Rev Port Cardiol 2011; 30: 897-903.
7. Lee PY, Alexander KP, Hammill BG, Pasquali SK, Peterson ED. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA 2001; 286: 708-713.
8. Killip T, Kimball JT. Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. Am J Cardiol 1967; 20: 457-464.
9. Nagamine M, Jiang HJ, Merrill CT. Trends in Elderly Hospitalizations, 1997-2004: statistical Brief #14. 2006.
10. Shiraki T, Saito D. Clinical features of acute myocardial infarction in elderly patients. Acta Med Okayama 2011; 65: 379-385.
11. Puria S, Kalia M, Mangat C etal. Profile Of Diabetes Mellitus In Elderly. The Internet Journal of Geriatrics and Gerontology 2008; 4: 1937-1941.
12. Avezum A, Makdisse M, Spencer F etal. Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2005; 149: 67-73.
13. Maggioni AP, Maseri A, Fresco C etal. Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. The Investigators of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2). N Engl J Med 1993; 329: 1442-1448.
14. Boersma E, Maas AC, Deckers JW, Simoons ML. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet 1996; 348: 771-775.
15. Berger PB, Ellis SG, Holmes DR Jr. etal. Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the global use of strategies to open occluded arteries in Acute Coronary Syndromes (GUSTO-IIb) trial. Circulation 1999; 100: 14-20.
16. Rittger H, Rieber J, Breithardt OA etal. Influence of age on pain perception in acute myocardial ischemia: a possible cause for delayed treatment in elderly patients. Int J Cardiol 2011; 149: 63-67.
17. Rogers WJ, Bowlby LJ, Chandra NC etal. Treatment of myocardial infarction in the United States (1990 to 1993). Observations from the National Registry of Myocardial Infarction. Circulation 1994; 90: 2103-2014.
18. Gheorghiade M, Bonow RO. Chronic heart failure in the United States: a manifestation of coronary artery disease. Circulation 1998; 97: 282-289.
19. Topalian S, Ginsberg F, Parrillo JE. Cardiogenic shock. Crit Care Med 2008; 36: S66-S74.
20. Steg PG, Dabbous OH, Feldman LJ etal. Determinants and prognostic impact of heart failure complicating acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE). Circulation 2004; 109: 494-499.
21. Holmes DR Jr. Cardiogenic shock: a lethal complication of acute myocardial infarction. Rev Cardiovasc Med 2003; 4: 131-135.
22. Danzi GB, Centola M, Pomidossi GA etal. Usefulness of primary angioplasty in nonagenarians with acute myocardial infarction. Am J Cardiol 2010; 106: 770-773.
23. De Luca G, van 't Hof AW, Ottervanger JP etal. Ageing, impaired myocardial perfusion, and mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty. Eur Heart J 2005; 26: 662-666.
24. White HD. Thrombolytic therapy in the elderly. Lancet 2000; 356: 2028-2030.
25. Thiemann DR, Coresh J, Schulman SP, Gerstenblith G, Oetgen WJ, Powe NR. Lack of benefit for intravenous thrombolysis in patients with myocardial infarction who are older than 75years. Circulation 2000; 101: 2239-2246.
26. Berger AK, Schulman KA, Gersh BJ etal. Primary coronary angioplasty vs thrombolysis for the management of acute myocardial infarction in elderly patients. JAMA 1999; 282: 341-348.
27. Bardaji A, Bueno H, Fernandez-Ortiz A, Cequier A, Auge JM, Heras M. Type of treatment and short-term outcome in elderly patients with acute myocardial infarction admitted to hospitals with a primary coronary angioplasty facility. The TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) Registry. Rev Esp Cardiol 2005; 58: 351-358.
28. Sakai K, Nagayama S, Ihara K etal. Primary percutaneous coronary intervention for acute myocardial infarction in the elderly aged ≥75years. Catheter Cardiovasc Interv 2011; 79: 50-56.
29. Bueno H, Betriu A, Heras M etal. Primary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies. Eur Heart J 2011; 32: 51-60.
30. Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J 2006; 27: 779-788.
31. Alexander KP, Newby LK, Armstrong PW etal. Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology. Circulation 2007; 115: 2570-2589.