메뉴 건너뛰기




Volumn 73, Issue 1, 2013, Pages 385-394

E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; MESSENGER RNA; PROTEIN P21; PROTEIN RNF126; SMALL INTERFERING RNA; SULFORHODAMINE B; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84871989736     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0562     Document Type: Article
Times cited : (62)

References (36)
  • 1
    • 1842486790 scopus 로고    scopus 로고
    • Ubiquitin and breast cancer
    • Ohta T, Fukuda M. Ubiquitin and breast cancer. Oncogene 2004;23:2079-88.
    • (2004) Oncogene , vol.23 , pp. 2079-2088
    • Ohta, T.1    Fukuda, M.2
  • 2
    • 3042538418 scopus 로고    scopus 로고
    • The ubiquitin system: From basic mechanisms to the patient bed
    • Ciechanover A, Iwai K. The ubiquitin system: from basic mechanisms to the patient bed. IUBMB Life 2004;56:193-201.
    • (2004) IUBMB Life , vol.56 , pp. 193-201
    • Ciechanover, A.1    Iwai, K.2
  • 4
    • 41649102468 scopus 로고    scopus 로고
    • Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
    • Shangary S, Qin D, McEachern D, Liu M, Miller RS, Qiu S, et al. Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc Natl Acad Sci U S A 2008;105:3933-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3933-3938
    • Shangary, S.1    Qin, D.2    McEachern, D.3    Liu, M.4    Miller, R.S.5    Qiu, S.6
  • 6
    • 67449119401 scopus 로고    scopus 로고
    • Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer
    • Soucy TA, Smith PG, Rolfe M. Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer. Clin Cancer Res 2009;15:3912-6.
    • (2009) Clin Cancer Res , vol.15 , pp. 3912-3916
    • Soucy, T.A.1    Smith, P.G.2    Rolfe, M.3
  • 7
    • 80051733972 scopus 로고    scopus 로고
    • Ubiquitination of E3 ligases: Self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms
    • de Bie P, Ciechanover A. Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms. Cell Death Differ 2011;18:1393-402.
    • (2011) Cell Death Differ , vol.18 , pp. 1393-1402
    • De Bie, P.1    Ciechanover, A.2
  • 8
    • 54749113690 scopus 로고    scopus 로고
    • Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2
    • Zheng M, Morgan-Lappe SE, Yang J, Bockbrader KM, Pamarthy D, Thomas D, et al. Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. Cancer Res 2008;68:7570-8.
    • (2008) Cancer Res , vol.68 , pp. 7570-7578
    • Zheng, M.1    Morgan-Lappe, S.E.2    Yang, J.3    Bockbrader, K.M.4    Pamarthy, D.5    Thomas, D.6
  • 9
    • 33748570421 scopus 로고    scopus 로고
    • Novel RING E3 ubiquitin ligases in breast cancer
    • Burger A, Amemiya Y, Kitching R, Seth AK. Novel RING E3 ubiquitin ligases in breast cancer. Neoplasia 2006;8:689-95.
    • (2006) Neoplasia , vol.8 , pp. 689-695
    • Burger, A.1    Amemiya, Y.2    Kitching, R.3    Seth, A.K.4
  • 10
    • 28544431575 scopus 로고    scopus 로고
    • A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer
    • Burger AM, Gao Y, Amemiya Y, Kahn HJ, Kitching R, Yang Y, et al. A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer. Cancer Res 2005;65:10401-12.
    • (2005) Cancer Res , vol.65 , pp. 10401-10412
    • Burger, A.M.1    Gao, Y.2    Amemiya, Y.3    Kahn, H.J.4    Kitching, R.5    Yang, Y.6
  • 11
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: Intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 2009;9:400-14.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 12
    • 77951985216 scopus 로고    scopus 로고
    • Examination of the expanding pathways for the regulation of p21 expression and activity
    • Jung YS, Qian Y, Chen X. Examination of the expanding pathways for the regulation of p21 expression and activity. Cell Signal 2010;22:1003-12.
    • (2010) Cell Signal , vol.22 , pp. 1003-1012
    • Jung, Y.S.1    Qian, Y.2    Chen, X.3
  • 13
    • 0032530151 scopus 로고    scopus 로고
    • Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins
    • Yu ZK, Gervais JL, Zhang H. Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins. Proc Natl Acad Sci U S A 1998;95:11324-9.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11324-11329
    • Yu, Z.K.1    Gervais, J.L.2    Zhang, H.3
  • 14
    • 51949098691 scopus 로고    scopus 로고
    • PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex
    • Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev 2008;22:2496-506.
    • (2008) Genes Dev , vol.22 , pp. 2496-2506
    • Abbas, T.1    Sivaprasad, U.2    Terai, K.3    Amador, V.4    Pagano, M.5    Dutta, A.6
  • 15
    • 34547174700 scopus 로고    scopus 로고
    • APC/C (Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase
    • Amador V, Ge S, Santamaria PG, Guardavaccaro D, Pagano M. APC/C (Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Mol Cell 2007;27:462-73.
    • (2007) Mol Cell , vol.27 , pp. 462-473
    • Amador, V.1    Ge, S.2    Santamaria, P.G.3    Guardavaccaro, D.4    Pagano, M.5
  • 16
    • 67651154117 scopus 로고    scopus 로고
    • Differential regulation of p53 and p21 byMKRN1E3 ligase controls cell cycle arrest and apoptosis
    • Lee EW, Lee MS, Camus S, Ghim J, Yang MR, Oh W, et al. Differential regulation of p53 and p21 byMKRN1E3 ligase controls cell cycle arrest and apoptosis. EMBO J 2009;28:2100-13.
    • (2009) EMBO J , vol.28 , pp. 2100-2113
    • Lee, E.W.1    Lee, M.S.2    Camus, S.3    Ghim, J.4    Yang, M.R.5    Oh, W.6
  • 18
    • 33750590972 scopus 로고    scopus 로고
    • Genetic and expression aberrations of e3 ubiquitin ligases in human breast cancer
    • Chen C, Seth AK, Aplin AE. Genetic and expression aberrations of e3 ubiquitin ligases in human breast cancer. Mol Cancer Res 2006;4:695-707.
    • (2006) Mol Cancer Res , vol.4 , pp. 695-707
    • Chen, C.1    Seth, A.K.2    Aplin, A.E.3
  • 19
    • 34248546185 scopus 로고    scopus 로고
    • Theamplified WWP1 gene is a potential molecular target in breast cancer
    • Chen C, Zhou Z, Ross JS, Zhou W, Dong JT. Theamplified WWP1 gene is a potential molecular target in breast cancer. Int J Cancer 2007;121:2834-41.
    • (2007) Int J Cancer , vol.121 , pp. 2834-2841
    • Chen, C.1    Zhou, Z.2    Ross, J.S.3    Zhou, W.4    Dong, J.T.5
  • 20
    • 29244464672 scopus 로고    scopus 로고
    • Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells
    • Chen C, Sun X, Guo P, Dong XY, Sethi P, Cheng X, et al. Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells. J Biol Chem 2005;280:41553-61.
    • (2005) J Biol Chem , vol.280 , pp. 41553-41561
    • Chen, C.1    Sun, X.2    Guo, P.3    Dong, X.Y.4    Sethi, P.5    Cheng, X.6
  • 21
    • 56349108922 scopus 로고    scopus 로고
    • WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis
    • Li Y, Zhou Z, Chen C. WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis. Cell Death Differ 2008;15:1941-51.
    • (2008) Cell Death Differ , vol.15 , pp. 1941-1951
    • Li, Y.1    Zhou, Z.2    Chen, C.3
  • 22
    • 77953158826 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation
    • Zhao D, Zheng HQ, Zhou Z, Chen C. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation. Cancer Res 2010;70:4728-38.
    • (2010) Cancer Res , vol.70 , pp. 4728-4738
    • Zhao, D.1    Zheng, H.Q.2    Zhou, Z.3    Chen, C.4
  • 23
    • 33644559042 scopus 로고    scopus 로고
    • KLF5 promotes cell proliferation and tumorigenesis through gene regulationin the TSU-Pr1 human bladder cancer cell line
    • Chen C, Benjamin MS, Sun X, Otto KB, Guo P, Dong XY, et al. KLF5 promotes cell proliferation and tumorigenesis through gene regulationin the TSU-Pr1 human bladder cancer cell line. Int J Cancer 2006;118:1346-55.
    • (2006) Int J Cancer , vol.118 , pp. 1346-1355
    • Chen, C.1    Benjamin, M.S.2    Sun, X.3    Otto, K.B.4    Guo, P.5    Dong, X.Y.6
  • 24
    • 34248216452 scopus 로고    scopus 로고
    • Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C
    • Di Fiore B, Pines J. Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C. J Cell Biol 2007;177:425-37.
    • (2007) J Cell Biol , vol.177 , pp. 425-437
    • Di Fiore, B.1    Pines, J.2
  • 25
    • 0032125559 scopus 로고    scopus 로고
    • Perturbation of TSG101 protein affects cell cycle progression
    • Zhong Q, Chen Y, Jones D, Lee WH. Perturbation of TSG101 protein affects cell cycle progression. Cancer Res 1998;58:2699-702.
    • (1998) Cancer Res , vol.58 , pp. 2699-2702
    • Zhong, Q.1    Chen, Y.2    Jones, D.3    Lee, W.H.4
  • 27
    • 57049133181 scopus 로고    scopus 로고
    • CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation
    • Nishitani H, Shiomi Y, Iida H, Michishita M, Takami T, Tsurimoto T.CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J Biol Chem 2008;283:29045-52.
    • (2008) J Biol Chem , vol.283 , pp. 29045-29052
    • Nishitani, H.1    Shiomi, Y.2    Iida, H.3    Michishita, M.4    Takami, T.5    Tsurimoto, T.6
  • 28
    • 0344688165 scopus 로고    scopus 로고
    • Analysis of a high-throughput yeast two-hybrid systemand its use to predict the function of intracellular proteins encoded within the human MHC class III region
    • Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM. Analysis of a high-throughput yeast two-hybrid systemand its use to predict the function of intracellular proteins encoded within the human MHC class III region. Genomics 2004;83:153-67.
    • (2004) Genomics , vol.83 , pp. 153-167
    • Lehner, B.1    Semple, J.I.2    Brown, S.E.3    Counsell, D.4    Campbell, R.D.5    Sanderson, C.M.6
  • 30
    • 58149307943 scopus 로고    scopus 로고
    • Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma
    • Tsukahara T, Kimura S, Ichimiya S, Torigoe T, Kawaguchi S, Wada T, et al. Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma. Cancer Sci 2009;100:47-53.
    • (2009) Cancer Sci , vol.100 , pp. 47-53
    • Tsukahara, T.1    Kimura, S.2    Ichimiya, S.3    Torigoe, T.4    Kawaguchi, S.5    Wada, T.6
  • 31
    • 34347385478 scopus 로고    scopus 로고
    • The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway
    • Yamasaki S, Yagishita N, Nishioka K, Nakajima T. The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway. Cell Cycle 2007;6:1319-23.
    • (2007) Cell Cycle , vol.6 , pp. 1319-1323
    • Yamasaki, S.1    Yagishita, N.2    Nishioka, K.3    Nakajima, T.4
  • 32
    • 70449729362 scopus 로고    scopus 로고
    • Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: Crosstalk between E3s in the endoplasmic reticulum
    • Shmueli A, Tsai YC, Yang M, Braun MA, Weissman AM. Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: crosstalk between E3s in the endoplasmic reticulum. Biochem Biophys Res Commun 2009;390:758-62.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 758-762
    • Shmueli, A.1    Tsai, Y.C.2    Yang, M.3    Braun, M.A.4    Weissman, A.M.5
  • 33
    • 46349101680 scopus 로고    scopus 로고
    • Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells
    • Kaulfuss S, Grzmil M, Hemmerlein B, Thelen P, Schweyer S, Neesen J, et al. Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells. Mol Endocrinol 2008;22:1606-21.
    • (2008) Mol Endocrinol , vol.22 , pp. 1606-1621
    • Kaulfuss, S.1    Grzmil, M.2    Hemmerlein, B.3    Thelen, P.4    Schweyer, S.5    Neesen, J.6
  • 34
    • 70449640172 scopus 로고    scopus 로고
    • Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression
    • Kaulfuss S, von Hardenberg S, Schweyer S, Herr AM, Laccone F, Wolf S, et al. Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression. Oncogene 2009;28:3971-82.
    • (2009) Oncogene , vol.28 , pp. 3971-3982
    • Kaulfuss, S.1    Von Hardenberg, S.2    Schweyer, S.3    Herr, A.M.4    Laccone, F.5    Wolf, S.6
  • 36
    • 82755190610 scopus 로고    scopus 로고
    • Tripartite motif 8 (TRIM8) modulates TNFalpha- and IL-1beta-triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination
    • Li Q, Yan J,MaoAP, Li C, Ran Y, Shu HB, et al. Tripartite motif 8 (TRIM8) modulates TNFalpha- and IL-1beta-triggered NF-kappaB activation by targeting TAK1 for K63-linked polyubiquitination. Proc Natl Acad Sci U S A 2011;108:19341-6.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 19341-19346
    • Li, Q.1    Yan, J.2    Mao, A.P.3    Li, C.4    Ran, Y.5    Shu, H.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.