메뉴 건너뛰기




Volumn 199, Issue 7, 2012, Pages 1025-1035

Mitotic spindle (DIS)orientation and DISease: Cause or consequence?

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHECKPOINT KINASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STATHMIN; UBIQUITIN PROTEIN LIGASE E3; VON HIPPEL LINDAU PROTEIN;

EID: 84871976995     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201209015     Document Type: Review
Times cited : (78)

References (154)
  • 1
    • 33845352555 scopus 로고    scopus 로고
    • Wnt signalling and the actin cytoskeleton
    • Akiyama, T., and Y. Kawasaki. 2006. Wnt signalling and the actin cytoskeleton. Oncogene. 25:7538-7544. http://dx.doi.org/10.1038/sj.onc.1210063
    • (2006) Oncogene , vol.25 , pp. 7538-7544
    • Akiyama, T.1    Kawasaki, Y.2
  • 2
    • 77953704592 scopus 로고    scopus 로고
    • Novel CENPJ mutation causes Seckel syndrome
    • Al-Dosari, M.S., R. Shaheen, D. Colak, and F.S. Alkuraya. 2010. Novel CENPJ mutation causes Seckel syndrome. J. Med. Genet. 47:411-414. http://dx.doi.org/10.1136/jmg.2009.076646
    • (2010) J. Med. Genet. , vol.47 , pp. 411-414
    • Al-Dosari, M.S.1    Shaheen, R.2    Colak, D.3    Alkuraya, F.S.4
  • 4
    • 0026042011 scopus 로고
    • Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia
    • Aplan, P.D., D.P. Lombardi, and I.R. Kirsch. 1991. Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia. Mol. Cell. Biol. 11:5462-5469.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5462-5469
    • Aplan, P.D.1    Lombardi, D.P.2    Kirsch, I.R.3
  • 5
    • 75349104314 scopus 로고    scopus 로고
    • Role of APC and its binding partners in regulating microtubules in mitosis
    • Bahmanyar, S., W.J. Nelson, and A.I. Barth. 2009. Role of APC and its binding partners in regulating microtubules in mitosis. Adv. Exp. Med. Biol. 656:65-74. http://dx.doi.org/10.1007/978-1-4419-1145-2_6
    • (2009) Adv. Exp. Med. Biol. , vol.656 , pp. 65-74
    • Bahmanyar, S.1    Nelson, W.J.2    Barth, A.I.3
  • 7
    • 77950566340 scopus 로고    scopus 로고
    • CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response
    • Barr, A.R., J.V. Kilmartin, and F. Gergely. 2010. CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. J. Cell Biol. 189:23-39. http://dx.doi.org/10.1083/jcb.200912163
    • (2010) J. Cell Biol. , vol.189 , pp. 23-39
    • Barr, A.R.1    Kilmartin, J.V.2    Gergely, F.3
  • 11
    • 0030048731 scopus 로고    scopus 로고
    • Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
    • Belmont, L.D., and T.J. Mitchison. 1996. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell. 84:623-631. http://dx.doi.org/10.1016/S0092-8674(00)81037-5
    • (1996) Cell , vol.84 , pp. 623-631
    • Belmont, L.D.1    Mitchison, T.J.2
  • 14
    • 84871986000 scopus 로고    scopus 로고
    • WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression
    • Bogoyevitch, M.A., Y.Y. Yeap, Z. Qu, K.R. Ngoei, Y.Y. Yip, T.T. Zhao, J.I. Heng, and D.C. Ng. 2012. WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression. J. Cell Sci.
    • (2012) J. Cell Sci.
    • Bogoyevitch, M.A.1    Yeap, Y.Y.2    Qu, Z.3    Ngoei, K.R.4    Yip, Y.Y.5    Zhao, T.T.6    Heng, J.I.7    Ng, D.C.8
  • 17
    • 84856290771 scopus 로고    scopus 로고
    • The centrosome in cells and organisms
    • Bornens, M. 2012. The centrosome in cells and organisms. Science. 335:422-426. http://dx.doi.org/10.1126/science.1209037
    • (2012) Science , vol.335 , pp. 422-426
    • Bornens, M.1
  • 18
    • 33751282353 scopus 로고    scopus 로고
    • Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies
    • Borrell-Pagès, M., D. Zala, S. Humbert, and F. Saudou. 2006. Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. Cell. Mol. Life Sci. 63:2642-2660. http://dx.doi.org/10.1007/s00018-006-6242-0
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 2642-2660
    • Borrell-pagès, M.1    Zala, D.2    Humbert, S.3    Saudou, F.4
  • 19
    • 84857691732 scopus 로고    scopus 로고
    • Deconstructing the centriole: structure and number control
    • Brito, D.A., S.M. Gouveia, and M. Bettencourt-Dias. 2012. Deconstructing the centriole: structure and number control. Curr. Opin. Cell Biol. 24:4-13. http://dx.doi.org/10.1016/j.ceb.2012.01.003
    • (2012) Curr. Opin. Cell Biol. , vol.24 , pp. 4-13
    • Brito, D.A.1    Gouveia, S.M.2    Bettencourt-dias, M.3
  • 20
    • 34748818856 scopus 로고    scopus 로고
    • APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice
    • Caldwell, C.M., R.A. Green, and K.B. Kaplan. 2007. APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J. Cell Biol. 178:1109-1120. http://dx.doi.org/10.1083/jcb.200703186
    • (2007) J. Cell Biol. , vol.178 , pp. 1109-1120
    • Caldwell, C.M.1    Green, R.A.2    Kaplan, K.B.3
  • 21
    • 80054793879 scopus 로고    scopus 로고
    • Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis
    • Capalbo, L., P.P. D'Avino, V. Archambault, and D.M. Glover. 2011. Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis. Proc. Natl. Acad. Sci. USA. 108:17343-17348. http://dx.doi.org/10.1073/pnas.1103720108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 17343-17348
    • Capalbo, L.1    D'avino, P.P.2    Archambault, V.3    Glover, D.M.4
  • 22
    • 82555187911 scopus 로고    scopus 로고
    • Oriented cell division in vertebrate embryogenesis
    • Castanon, I., and M. González-Gaitán. 2011. Oriented cell division in vertebrate embryogenesis. Curr. Opin. Cell Biol. 23:697-704. http://dx.doi .org/10.1016/j.ceb.2011.09.009
    • (2011) Curr. Opin. Cell Biol. , vol.23 , pp. 697-704
    • Castanon, I.1    González-gaitán, M.2
  • 23
    • 49649092093 scopus 로고    scopus 로고
    • Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability
    • Castellanos, E., P. Dominguez, and C. Gonzalez. 2008. Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. Curr. Biol. 18:1209-1214. http://dx.doi.org/10.1016/j.cub.2008.07.029
    • (2008) Curr. Biol. , vol.18 , pp. 1209-1214
    • Castellanos, E.1    Dominguez, P.2    Gonzalez, C.3
  • 24
    • 27144555447 scopus 로고    scopus 로고
    • Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
    • Caussinus, E., and C. Gonzalez. 2005. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat. Genet. 37:1125-1129. http://dx.doi.org/10.1038/ng1632
    • (2005) Nat. Genet. , vol.37 , pp. 1125-1129
    • Caussinus, E.1    Gonzalez, C.2
  • 28
    • 33947104197 scopus 로고    scopus 로고
    • A single type of progenitor cell maintains normal epidermis
    • Clayton, E., D.P. Doupé, A.M. Klein, D.J. Winton, B.D. Simons, and P.H. Jones. 2007. A single type of progenitor cell maintains normal epidermis. Nature. 446:185-189. http://dx.doi.org/10.1038/nature05574
    • (2007) Nature , vol.446 , pp. 185-189
    • Clayton, E.1    Doupé, D.P.2    Klein, A.M.3    Winton, D.J.4    Simons, B.D.5    Jones, P.H.6
  • 29
    • 5444222543 scopus 로고    scopus 로고
    • lis-1 is required for dyneindependent cell division processes in C. elegans embryos
    • Cockell, M.M., K. Baumer, and P. Gönczy. 2004. lis-1 is required for dyneindependent cell division processes in C. elegans embryos. J. Cell Sci. 117:4571-4582. http://dx.doi.org/10.1242/jcs.01344
    • (2004) J. Cell Sci. , vol.117 , pp. 4571-4582
    • Cockell, M.M.1    Baumer, K.2    Gönczy, P.3
  • 30
    • 0034805050 scopus 로고    scopus 로고
    • Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans
    • Dawe, A.L., K.A. Caldwell, P.M. Harris, N.R. Morris, and G.A. Caldwell. 2001. Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans. Dev. Genes Evol. 211:434-441. http://dx.doi.org/10.1007/s004270100176
    • (2001) Dev. Genes Evol. , vol.211 , pp. 434-441
    • Dawe, A.L.1    Caldwell, K.A.2    Harris, P.M.3    Morris, N.R.4    Caldwell, G.A.5
  • 31
    • 79953326597 scopus 로고    scopus 로고
    • The cilia protein IFT88 is required for spindle orientation in mitosis
    • Delaval, B., A. Bright, N.D. Lawson, and S. Doxsey. 2011. The cilia protein IFT88 is required for spindle orientation in mitosis. Nat. Cell Biol. 13:461-468. http://dx.doi.org/10.1038/ncb2202
    • (2011) Nat. Cell Biol. , vol.13 , pp. 461-468
    • Delaval, B.1    Bright, A.2    Lawson, N.D.3    Doxsey, S.4
  • 32
    • 17444444915 scopus 로고    scopus 로고
    • A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome
    • des Portes, V., J.M. Pinard, P. Billuart, M.C. Vinet, A. Koulakoff, A. Carrié, A. Gelot, E. Dupuis, J. Motte, Y. Berwald-Netter, et al. 1998. A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. Cell. 92:51-61. http://dx.doi.org/10.1016/S0092-8674(00)80898-3
    • (1998) Cell , vol.92 , pp. 51-61
    • Des Portes, V.1    Pinard, J.M.2    Billuart, P.3    Vinet, M.C.4    Koulakoff, A.5    Carrié, A.6    Gelot, A.7    Dupuis, E.8    Motte, J.9    Berwald-netter, Y.10
  • 34
    • 84865222310 scopus 로고    scopus 로고
    • Defining the mode of tumour growth by clonal analysis
    • Driessens, G., B. Beck, A. Caauwe, B.D. Simons, and C. Blanpain. 2012. Defining the mode of tumour growth by clonal analysis. Nature. 488:527-530. http://dx.doi.org/10.1038/nature11344
    • (2012) Nature , vol.88 , pp. 527-530
    • Driessens, G.1    Beck, B.2    Caauwe, A.3    Simons, B.D.4    Blanpain, C.5
  • 35
    • 0035205087 scopus 로고    scopus 로고
    • A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
    • Du, Q., P.T. Stukenberg, and I.G. Macara. 2001. A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat. Cell Biol. 3:1069-1075. http://dx.doi.org/10.1038/ncb1201-1069
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1069-1075
    • Du, Q.1    Stukenberg, P.T.2    Macara, I.G.3
  • 36
    • 0035812719 scopus 로고    scopus 로고
    • Guidance of cell migration by the Drosophila PDGF/VEGF receptor
    • Duchek, P., K. Somogyi, G. Jékely, S. Beccari, and P. Rørth. 2001. Guidance of cell migration by the Drosophila PDGF/VEGF receptor. Cell. 107:17-26. http://dx.doi.org/10.1016/S0092-8674(01)00502-5
    • (2001) Cell , vol.107 , pp. 17-26
    • Duchek, P.1    Somogyi, K.2    Jékely, G.3    Beccari, S.4    Rørth, P.5
  • 37
    • 77951219416 scopus 로고    scopus 로고
    • Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability
    • Duchi, S., L. Fagnocchi, V. Cavaliere, A. Hsouna, G. Gargiulo, and T. Hsu. 2010. Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability. Development. 137:1493-1503. http://dx.doi.org/10.1242/dev.042804
    • (2010) Development. , vol.137 , pp. 1493-1503
    • Duchi, S.1    Fagnocchi, L.2    Cavaliere, V.3    Hsouna, A.4    Gargiulo, G.5    Hsu, T.6
  • 39
    • 5144222593 scopus 로고    scopus 로고
    • Mitotic spindle regulation by Nde1 controls cerebral cortical size
    • Feng, Y., and C.A. Walsh. 2004. Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron. 44:279-293. http://dx.doi.org/10.1016/j.neuron.2004.09.023
    • (2004) Neuron , vol.44 , pp. 279-293
    • Feng, Y.1    Walsh, C.A.2
  • 40
    • 0036985699 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications
    • Ferrara, N. 2002. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin. Oncol. 29(6, Suppl 16):10-14. http://dx.doi.org/10.1016/S0093-7754(02)70064-X
    • (2002) Semin. Oncol. , vol.29 , Issue.6 SUPPL. 16 , pp. 10-14
    • Ferrara, N.1
  • 43
    • 33745883798 scopus 로고    scopus 로고
    • Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells
    • Fish, J.L., Y. Kosodo, W. Enard, S. Pääbo, and W.B. Huttner. 2006. Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells. Proc. Natl. Acad. Sci. USA. 103:10438-10443. http://dx.doi.org/10.1073/pnas.0604066103
    • (2006) Proc. Natl. Acad. Sci. USA. , vol.103 , pp. 10438-10443
    • Fish, J.L.1    Kosodo, Y.2    Enard, W.3    Pääbo, S.4    Huttner, W.B.5
  • 46
    • 0034902674 scopus 로고    scopus 로고
    • Disease model: familial adenomatous polyposis
    • Fodde, R., and R. Smits. 2001. Disease model: familial adenomatous polyposis. Trends Mol. Med. 7:369-373. http://dx.doi.org/10.1016/S1471-4914(01)02050-0
    • (2001) Trends Mol. Med. , vol.7 , pp. 369-373
    • Fodde, R.1    Smits, R.2
  • 47
    • 36749102487 scopus 로고    scopus 로고
    • Multitasking by pVHL in tumour suppression
    • Frew, I.J., and W. Krek. 2007. Multitasking by pVHL in tumour suppression. Curr. Opin. Cell Biol. 19:685-690. http://dx.doi.org/10.1016\j.ceb.2007.10.001
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 685-690
    • Frew, I.J.1    Krek, W.2
  • 48
    • 47049090632 scopus 로고    scopus 로고
    • pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
    • Frew, I.J., C.R. Thoma, S. Georgiev, A. Minola, M. Hitz, M. Montani, H. Moch, and W. Krek. 2008. pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation. EMBO J. 27:1747-1757. http://dx.doi.org/10.1038/emboj.2008.96
    • (2008) EMBO J. , vol.27 , pp. 1747-1757
    • Frew, I.J.1    Thoma, C.R.2    Georgiev, S.3    Minola, A.4    Hitz, M.5    Montani, M.6    Moch, H.7    Krek, W.8
  • 49
    • 74749103945 scopus 로고    scopus 로고
    • UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration
    • Fridolfsson, H.N., N. Ly, M. Meyerzon, and D.A. Starr. 2010. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev. Biol. 338:237-250. http://dx.doi.org/10.1016/j.ydbio.2009.12.004
    • (2010) Dev. Biol. , vol.338 , pp. 237-250
    • Fridolfsson, H.N.1    Ly, N.2    Meyerzon, M.3    Starr, D.A.4
  • 50
    • 0032498306 scopus 로고    scopus 로고
    • Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein
    • Gleeson, J.G., K.M. Allen, J.W. Fox, E.D. Lamperti, S. Berkovic, I. Scheffer, E.C. Cooper, W.B. Dobyns, S.R. Minnerath, M.E. Ross, and C.A. Walsh. 1998. Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein. Cell. 92:63-72. http://dx.doi.org/10.1016/S0092-8674(00)80899-5
    • (1998) Cell , vol.92 , pp. 63-72
    • Gleeson, J.G.1    Allen, K.M.2    Fox, J.W.3    Lamperti, E.D.4    Berkovic, S.5    Scheffer, I.6    Cooper, E.C.7    Dobyns, W.B.8    Minnerath, S.R.9    Ross, M.E.10    Walsh, C.A.11
  • 51
    • 79955884502 scopus 로고    scopus 로고
    • Mitotic spindle: focus on the function of huntingtin
    • Godin, J.D., and S. Humbert. 2011. Mitotic spindle: focus on the function of huntingtin. Int. J. Biochem. Cell Biol. 43:852-856. http://dx.doi.org/10.1016/j.biocel.2011.03.009
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 852-856
    • Godin, J.D.1    Humbert, S.2
  • 53
    • 0035462443 scopus 로고    scopus 로고
    • zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly
    • Gönczy, P., J.M. Bellanger, M. Kirkham, A. Pozniakowski, K. Baumer, J.B. Phillips, and A.A. Hyman. 2001. zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly. Dev. Cell. 1:363-375. http://dx.doi.org/10.1016/S1534-5807(01)00046-6
    • (2001) Dev. Cell. , vol.1 , pp. 363-375
    • Gönczy, P.1    Bellanger, J.M.2    Kirkham, M.3    Pozniakowski, A.4    Baumer, K.5    Phillips, J.B.6    Hyman, A.A.7
  • 54
    • 0346849717 scopus 로고    scopus 로고
    • Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
    • Green, R.A., and K.B. Kaplan. 2003. Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J. Cell Biol. 163:949-961. http://dx.doi.org/10.1083/jcb.200307070
    • (2003) J. Cell Biol. , vol.163 , pp. 949-961
    • Green, R.A.1    Kaplan, K.B.2
  • 55
    • 80455177095 scopus 로고    scopus 로고
    • MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway
    • Gruber, R., Z. Zhou, M. Sukchev, T. Joerss, P.O. Frappart, and Z.Q. Wang. 2011. MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat. Cell Biol. 13:1325-1334. http://dx.doi.org/10.1038/ncb2342
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1325-1334
    • Gruber, R.1    Zhou, Z.2    Sukchev, M.3    Joerss, T.4    Frappart, P.O.5    Wang, Z.Q.6
  • 58
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., and R.A. Weinberg. 2000. The hallmarks of cancer. Cell. 100:57-70. http://dx.doi.org/10.1016/S0092-8674(00)81683-9
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 59
    • 77950076985 scopus 로고    scopus 로고
    • Neurogenic radial glia in the outer subventricular zone of human neocortex
    • Hansen, D.V., J.H. Lui, P.R. Parker, and A.R. Kriegstein. 2010. Neurogenic radial glia in the outer subventricular zone of human neocortex. Nature. 464:554-561. http://dx.doi.org/10.1038/nature08845
    • (2010) Nature , vol.464 , pp. 554-561
    • Hansen, D.V.1    Lui, J.H.2    Parker, P.R.3    Kriegstein, A.R.4
  • 60
    • 0033230616 scopus 로고    scopus 로고
    • Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
    • Harada, N., Y. Tamai, T. Ishikawa, B. Sauer, K. Takaku, M. Oshima, and M.M. Taketo. 1999. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 18:5931-5942. http://dx.doi.org/10.1093/emboj/18.21.5931
    • (1999) EMBO J , vol.18 , pp. 5931-5942
    • Harada, N.1    Tamai, Y.2    Ishikawa, T.3    Sauer, B.4    Takaku, K.5    Oshima, M.6    Taketo, M.M.7
  • 61
    • 0037418320 scopus 로고    scopus 로고
    • Mitotic spindle rotation and mode of cell division in the developing telencephalon
    • Haydar, T.F., E. Ang Jr., and P. Rakic. 2003. Mitotic spindle rotation and mode of cell division in the developing telencephalon. Proc. Natl. Acad. Sci. USA. 100:2890-2895. http://dx.doi.org/10.1073/pnas.0437969100
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2890-2895
    • Haydar, T.F.1    Ang Jr., E.2    Rakic, P.3
  • 62
    • 0037223823 scopus 로고    scopus 로고
    • Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
    • Hergovich, A., J. Lisztwan, R. Barry, P. Ballschmieter, and W. Krek. 2003. Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nat. Cell Biol. 5:64-70. http://dx.doi.org/10.1038/ncb899
    • (2003) Nat. Cell Biol. , vol.5 , pp. 64-70
    • Hergovich, A.1    Lisztwan, J.2    Barry, R.3    Ballschmieter, P.4    Krek, W.5
  • 64
    • 79953038262 scopus 로고    scopus 로고
    • PTEN loss in the continuum of common cancers, rare syndromes and mouse models
    • Hollander, M.C., G.M. Blumenthal, and P.A. Dennis. 2011. PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat. Rev. Cancer. 11:289-301. http://dx.doi.org/10.1038/nrc3037
    • (2011) Nat. Rev. Cancer. , vol.11 , pp. 289-301
    • Hollander, M.C.1    Blumenthal, G.M.2    Dennis, P.A.3
  • 65
    • 84861356212 scopus 로고    scopus 로고
    • Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms
    • Hsu, T. 2012. Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms. Oncogene. 31:2247-2257. http://dx.doi.org/10.1038/onc.2011.442
    • (2012) Oncogene , vol.31 , pp. 2247-2257
    • Hsu, T.1
  • 66
    • 84865679752 scopus 로고    scopus 로고
    • Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor
    • Huang, J., A.J. Roberts, A.E. Leschziner, and S.L. Reck-Peterson. 2012. Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor. Cell. 150:975-986. http://dx.doi.org/10.1016/j.cell.2012.07.022
    • (2012) Cell , vol.150 , pp. 975-986
    • Huang, J.1    Roberts, A.J.2    Leschziner, A.E.3    Reck-peterson, S.L.4
  • 67
    • 0031058652 scopus 로고    scopus 로고
    • Asymmetric division and polarity of neuroepithelial cells
    • Huttner, W.B., and M. Brand. 1997. Asymmetric division and polarity of neuroepithelial cells. Curr. Opin. Neurobiol. 7:29-39. http://dx.doi.org/10.1016/S0959-4388(97)80117-1
    • (1997) Curr. Opin. Neurobiol. , vol.7 , pp. 29-39
    • Huttner, W.B.1    Brand, M.2
  • 69
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
    • Kaelin, W.G. Jr. 2008. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat. Rev. Cancer. 8:865-873. http://dx.doi.org/10.1038/nrc2502
    • (2008) Nat. Rev. Cancer. , vol.8 , pp. 865-873
    • Kaelin, W.G.Jr.1
  • 71
  • 72
    • 0035890258 scopus 로고    scopus 로고
    • Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex
    • Kataoka, N., M.D. Diem, V.N. Kim, J. Yong, and G. Dreyfuss. 2001. Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. EMBO J. 20:6424-6433. http://dx.doi.org/10.1093/emboj/20.22.6424
    • (2001) EMBO J , vol.20 , pp. 6424-6433
    • Kataoka, N.1    Diem, M.D.2    Kim, V.N.3    Yong, J.4    Dreyfuss, G.5
  • 73
    • 84856770762 scopus 로고    scopus 로고
    • Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL
    • Kitagawa, D., G. Kohlmaier, D. Keller, P. Strnad, F.R. Balestra, I. Flückiger, and P. Gönczy. 2011. Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL. J. Cell Sci. 124:3884-3893. http://dx.doi.org/10.1242/jcs.089888
    • (2011) J. Cell Sci. , vol.124 , pp. 3884-3893
    • Kitagawa, D.1    Kohlmaier, G.2    Keller, D.3    Strnad, P.4    Balestra, F.R.5    Flückiger, I.6    Gönczy, P.7
  • 74
    • 84863573069 scopus 로고    scopus 로고
    • Errorprone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension
    • Kolano, A., S. Brunet, A.D. Silk, D.W. Cleveland, and M.H. Verlhac. 2012. Errorprone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proc. Natl. Acad. Sci. USA. 109:E1858-E1867. http://dx.doi.org/10.1073/pnas.1204686109
    • (2012) Proc. Natl. Acad. Sci. USA. , vol.109
    • Kolano, A.1    Brunet, S.2    Silk, A.D.3    Cleveland, D.W.4    Verlhac, M.H.5
  • 75
    • 37749022460 scopus 로고    scopus 로고
    • Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis
    • Konno, D., G. Shioi, A. Shitamukai, A. Mori, H. Kiyonari, T. Miyata, and F. Matsuzaki. 2008. Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat. Cell Biol. 10:93-101. http://dx.doi.org/10.1038/ncb1673
    • (2008) Nat. Cell Biol. , vol.10 , pp. 93-101
    • Konno, D.1    Shioi, G.2    Shitamukai, A.3    Mori, A.4    Kiyonari, H.5    Miyata, T.6    Matsuzaki, F.7
  • 76
    • 3042541528 scopus 로고    scopus 로고
    • Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells
    • Kosodo, Y., K. Röper, W. Haubensak, A.M. Marzesco, D. Corbeil, and W.B. Huttner. 2004. Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. EMBO J. 23:2314-2324. http://dx.doi.org/10.1038/sj.emboj.7600223
    • (2004) EMBO J , vol.23 , pp. 2314-2324
    • Kosodo, Y.1    Röper, K.2    Haubensak, W.3    Marzesco, A.M.4    Corbeil, D.5    Huttner, W.B.6
  • 79
    • 62649118818 scopus 로고    scopus 로고
    • Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly
    • Kumar, A., S.C. Girimaji, M.R. Duvvari, and S.H. Blanton. 2009. Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly. Am. J. Hum. Genet. 84:286-290. http://dx.doi.org/10.1016/j.ajhg.2009.01.017
    • (2009) Am. J. Hum. Genet. , vol.84 , pp. 286-290
    • Kumar, A.1    Girimaji, S.C.2    Duvvari, M.R.3    Blanton, S.H.4
  • 80
    • 39149089317 scopus 로고    scopus 로고
    • Structural insights into the exon junction complex
    • Le Hir, H., and G.R. Andersen. 2008. Structural insights into the exon junction complex. Curr. Opin. Struct. Biol. 18:112-119. http://dx.doi.org/10.1016/j.sbi.2007.11.002
    • (2008) Curr. Opin. Struct. Biol. , vol.18 , pp. 112-119
    • Le Hir, H.1    Andersen, G.R.2
  • 81
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler, T., and E. Fuchs. 2005. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature. 437:275-280. http://dx.doi.org/10.1038/nature03922
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 82
    • 24144463731 scopus 로고    scopus 로고
    • Centrosome duplication and nematodes: recent insights from an old relationship
    • Leidel, S., and P. Gönczy. 2005. Centrosome duplication and nematodes: recent insights from an old relationship. Dev. Cell. 9:317-325. http://dx.doi.org/10.1016/j.devcel.2005.08.004
    • (2005) Dev. Cell. , vol.9 , pp. 317-325
    • Leidel, S.1    Gönczy, P.2
  • 83
    • 77954952965 scopus 로고    scopus 로고
    • Neural stem cells: the need for a proper orientation
    • Lesage, B., I. Gutierrez, E. Martí, and C. Gonzalez. 2010. Neural stem cells: the need for a proper orientation. Curr. Opin. Genet. Dev. 20:438-442. http://dx.doi.org/10.1016/j.gde.2010.04.013
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 438-442
    • Lesage, B.1    Gutierrez, I.2    Martí, E.3    Gonzalez, C.4
  • 84
    • 0034652033 scopus 로고    scopus 로고
    • mag-1, a homolog of Drosophila mago nashi, regulates hermaphrodite germ-line sex determination in Caenorhabditis elegans
    • Li, W., R. Boswell, and W.B. Wood. 2000. mag-1, a homolog of Drosophila mago nashi, regulates hermaphrodite germ-line sex determination in Caenorhabditis elegans. Dev. Biol. 218:172-182. http://dx.doi.org/10.1006/dbio.1999.9593
    • (2000) Dev. Biol. , vol.218 , pp. 172-182
    • Li, W.1    Boswell, R.2    Wood, W.B.3
  • 85
    • 51049115975 scopus 로고    scopus 로고
    • ASPM is a novel marker for vascular invasion, early recurrence, and poor prognosis of hepatocellular carcinoma
    • Lin, S.Y., H.W. Pan, S.H. Liu, Y.M. Jeng, F.C. Hu, S.Y. Peng, P.L. Lai, and H.C. Hsu. 2008. ASPM is a novel marker for vascular invasion, early recurrence, and poor prognosis of hepatocellular carcinoma. Clin. Cancer Res. 14:4814-4820. http://dx.doi.org/10.1158/1078-0432.CCR-07-5262
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4814-4820
    • Lin, S.Y.1    Pan, H.W.2    Liu, S.H.3    Jeng, Y.M.4    Hu, F.C.5    Peng, S.Y.6    Lai, P.L.7    Hsu, H.C.8
  • 87
    • 0031040866 scopus 로고    scopus 로고
    • Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome
    • Lo Nigro, C., C.S. Chong, A.C. Smith, W.B. Dobyns, R. Carrozzo, and D.H. Ledbetter. 1997. Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome. Hum. Mol. Genet. 6:157-164. http://dx.doi.org/10.1093/hmg/6.2.157
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 157-164
    • Lo Nigro, C.1    Chong, C.S.2    Smith, A.C.3    Dobyns, W.B.4    Carrozzo, R.5    Ledbetter, D.H.6
  • 88
  • 89
    • 79952758980 scopus 로고    scopus 로고
    • Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance
    • Löffler, H., A. Fechter, M. Matuszewska, R. Saffrich, M. Mistrik, J. Marhold, C. Hornung, F. Westermann, J. Bartek, and A. Krämer. 2011. Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance. Cancer Res. 71:2129-2139. http://dx.doi.org/10.1158/0008-5472.CAN-10-2684
    • (2011) Cancer Res. , vol.71 , pp. 2129-2139
    • Löffler, H.1    Fechter, A.2    Matuszewska, M.3    Saffrich, R.4    Mistrik, M.5    Marhold, J.6    Hornung, C.7    Westermann, F.8    Bartek, J.9    Krämer, A.10
  • 90
    • 0034627760 scopus 로고    scopus 로고
    • LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans
    • Lorson, M.A., H.R. Horvitz, and S. van den Heuvel. 2000. LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J. Cell Biol. 148:73-86. http://dx.doi.org/10.1083/jcb.148.1.73
    • (2000) J. Cell Biol. , vol.148 , pp. 73-86
    • Lorson, M.A.1    Horvitz, H.R.2    van den Heuvel, S.3
  • 91
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: impact, heterogeneity, and uncertainty
    • Magee, J.A., E. Piskounova, and S.J. Morrison. 2012. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell. 21:283-296. http://dx.doi.org/10.1016/j.ccr.2012.03.003
    • (2012) Cancer Cell. , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 92
    • 77956903803 scopus 로고    scopus 로고
    • Tumor-host interactions: a far-reaching relationship
    • McAllister, S.S., and R.A. Weinberg. 2010. Tumor-host interactions: a far-reaching relationship. J. Clin. Oncol. 28:4022-4028. http://dx.doi.org/10.1200/JCO.2010.28.4257
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4022-4028
    • Mcallister, S.S.1    Weinberg, R.A.2
  • 93
    • 41549117418 scopus 로고    scopus 로고
    • Cell regulation by the Apc protein Apc as master regulator of epithelia
    • McCartney, B.M., and I.S. Näthke. 2008. Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr. Opin. Cell Biol. 20:186-193. http://dx.doi.org/10.1016/j.ceb.2008.02.001
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 186-193
    • Mccartney, B.M.1    Näthke, I.S.2
  • 94
    • 0034789121 scopus 로고    scopus 로고
    • Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
    • McCartney, B.M., D.G. McEwen, E. Grevengoed, P. Maddox, A. Bejsovec, and M. Peifer. 2001. Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nat. Cell Biol. 3:933-938. http://dx.doi.org/10.1038/ncb1001-933
    • (2001) Nat. Cell Biol. , vol.3 , pp. 933-938
    • Mccartney, B.M.1    Mcewen, D.G.2    Grevengoed, E.3    Maddox, P.4    Bejsovec, A.5    Peifer, M.6
  • 95
    • 77951701022 scopus 로고    scopus 로고
    • LIS1 and NudE induce a persistent dynein force-producing state
    • McKenney, R.J., M. Vershinin, A. Kunwar, R.B. Vallee, and S.P. Gross. 2010. LIS1 and NudE induce a persistent dynein force-producing state. Cell. 141:304-314. http://dx.doi.org/10.1016/j.cell.2010.02.035
    • (2010) Cell , vol.141 , pp. 304-314
    • Mckenney, R.J.1    Vershinin, M.2    Kunwar, A.3    Vallee, R.B.4    Gross, S.P.5
  • 96
    • 79960921403 scopus 로고    scopus 로고
    • Cdk5rap2 exposes the centrosomal root of microcephaly syndromes
    • Megraw, T.L., J.T. Sharkey, and R.S. Nowakowski. 2011. Cdk5rap2 exposes the centrosomal root of microcephaly syndromes. Trends Cell Biol. 21:470-480. http://dx.doi.org/10.1016/j.tcb.2011.04.007
    • (2011) Trends Cell Biol. , vol.21 , pp. 470-480
    • Megraw, T.L.1    Sharkey, J.T.2    Nowakowski, R.S.3
  • 97
    • 80052028694 scopus 로고    scopus 로고
    • Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?
    • Minde, D.P., Z. Anvarian, S.G. Rüdiger, and M.M. Maurice. 2011. Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer? Mol. Cancer. 10:101. http://dx.doi.org/10.1186/1476-4598-10-101
    • (2011) Mol. Cancer. , vol.10 , pp. 101
    • Minde, D.P.1    Anvarian, Z.2    Rüdiger, S.G.3    Maurice, M.M.4
  • 98
    • 35248832664 scopus 로고    scopus 로고
    • Two betas or not two betas: regulation of asymmetric division by beta-catenin
    • Mizumoto, K., and H. Sawa. 2007. Two betas or not two betas: regulation of asymmetric division by beta-catenin. Trends Cell Biol. 17:465-473. http://dx.doi.org/10.1016/j.tcb.2007.08.004
    • (2007) Trends Cell Biol. , vol.17 , pp. 465-473
    • Mizumoto, K.1    Sawa, H.2
  • 99
    • 79960207659 scopus 로고    scopus 로고
    • Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development
    • Morin, X., and Y. Bellaïche. 2011. Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development. Dev. Cell. 21:102-119. http://dx.doi.org/10.1016/j.devcel.2011.06.012
    • (2011) Dev. Cell. , vol.21 , pp. 102-119
    • Morin, X.1    Bellaïche, Y.2
  • 100
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison, S.J., and J. Kimble. 2006. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature. 441:1068-1074. http://dx.doi.org/10.1038/nature04956
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 101
    • 33845234807 scopus 로고    scopus 로고
    • Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC
    • Näthke, I. 2006. Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. Nat. Rev. Cancer. 6:967-974. http://dx.doi.org/10.1038/nrc2010
    • (2006) Nat. Rev. Cancer. , vol.6 , pp. 967-974
    • Näthke, I.1
  • 103
    • 42149188826 scopus 로고    scopus 로고
    • Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis
    • Noctor, S.C., V. Martínez-Cerdeño, and A.R. Kriegstein. 2008. Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis. J. Comp. Neurol. 508:28-44. http://dx.doi.org/10.1002/cne.21669
    • (2008) J. Comp. Neurol. , vol.508 , pp. 28-44
    • Noctor, S.C.1    Martínez-cerdeño, V.2    Kriegstein, A.R.3
  • 104
    • 0032238299 scopus 로고    scopus 로고
    • The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
    • Ogg, S., and G. Ruvkun. 1998. The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Mol. Cell. 2:887-893. http://dx.doi.org/10.1016/S1097-2765(00)80303-2
    • (1998) Mol. Cell. , vol.2 , pp. 887-893
    • Ogg, S.1    Ruvkun, G.2
  • 105
    • 0037154327 scopus 로고    scopus 로고
    • RNA processing: splicing and the cytoplasmic localisation of mRNA
    • Palacios, I.M. 2002. RNA processing: splicing and the cytoplasmic localisation of mRNA. Curr. Biol. 12:R50-R52. http://dx.doi.org/10.1016/S0960-9822(01)00671-6
    • (2002) Curr. Biol. , vol.12
    • Palacios, I.M.1
  • 106
    • 79953156769 scopus 로고    scopus 로고
    • Mitotic spindle misorientation in cancer- out of alignment and into the fire
    • Pease, J.C., and J.S. Tirnauer. 2011. Mitotic spindle misorientation in cancer- out of alignment and into the fire. J. Cell Sci. 124:1007-1016. http://dx.doi.org/10.1242/jcs.081406
    • (2011) J. Cell Sci. , vol.124 , pp. 1007-1016
    • Pease, J.C.1    Tirnauer, J.S.2
  • 107
    • 84860228903 scopus 로고    scopus 로고
    • An oblique view on the role of spindle orientation in vertebrate neurogenesis
    • Peyre, E., and X. Morin. 2012. An oblique view on the role of spindle orientation in vertebrate neurogenesis. Dev. Growth Differ. 54:287-305. http://dx.doi.org/10.1111/j.1440-169X.2012.01350.x
    • (2012) Dev. Growth Differ. , vol.54 , pp. 287-305
    • Peyre, E.1    Morin, X.2
  • 108
    • 80054841867 scopus 로고    scopus 로고
    • Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex
    • Postiglione, M.P., C. Jüschke, Y. Xie, G.A. Haas, C. Charalambous, and J.A. Knoblich. 2011. Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 72:269-284. http://dx.doi.org/10.1016/j.neuron.2011.09.022
    • (2011) Neuron , vol.72 , pp. 269-284
    • Postiglione, M.P.1    Jüschke, C.2    Xie, Y.3    Haas, G.A.4    Charalambous, C.5    Knoblich, J.A.6
  • 109
    • 77649134493 scopus 로고    scopus 로고
    • Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction
    • Pramparo, T., Y.H. Youn, J. Yingling, S. Hirotsune, and A. Wynshaw-Boris. 2010. Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction. J. Neurosci. 30:3002-3012. http://dx.doi.org/10.1523/JNEUROSCI.4851-09.2010
    • (2010) J. Neurosci. , vol.30 , pp. 3002-3012
    • Pramparo, T.1    Youn, Y.H.2    Yingling, J.3    Hirotsune, S.4    Wynshaw-boris, A.5
  • 112
    • 77950858612 scopus 로고    scopus 로고
    • NuMA after 30 years: the matrix revisited
    • Radulescu, A.E., and D.W. Cleveland. 2010. NuMA after 30 years: the matrix revisited. Trends Cell Biol. 20:214-222. http://dx.doi.org/10.1016/j.tcb.2010.01.003
    • (2010) Trends Cell Biol. , vol.20 , pp. 214-222
    • Radulescu, A.E.1    Cleveland, D.W.2
  • 113
    • 0027176708 scopus 로고
    • Isolation of a Miller-Diekerlissencephaly gene containing G protein beta-subunit-like repeats
    • Reiner, O., R. Carrozzo, Y. Shen, M. Wehnert, F. Faustinella, W.B. Dobyns, C.T. Caskey, and D.H. Ledbetter. 1993. Isolation of a Miller-Diekerlissencephaly gene containing G protein beta-subunit-like repeats. Nature. 364:717-721. http://dx.doi.org/10.1038/364717a0
    • (1993) Nature , vol.364 , pp. 717-721
    • Reiner, O.1    Carrozzo, R.2    Shen, Y.3    Wehnert, M.4    Faustinella, F.5    Dobyns, W.B.6    Caskey, C.T.7    Ledbetter, D.H.8
  • 114
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya, T., and H. Clevers. 2005. Wnt signalling in stem cells and cancer. Nature. 434:843-850. http://dx.doi.org/10.1038/nature03319
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 115
    • 55949096455 scopus 로고    scopus 로고
    • Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?
    • Rusan, N.M., K. Akong, and M. Peifer. 2008. Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting? J. Cell Biol. 183:203-212. http://dx.doi.org/10.1083/jcb.200807079
    • (2008) J Cell Biol. , vol.183 , pp. 203-212
    • Rusan, N.M.1    Akong, K.2    Peifer, M.3
  • 116
    • 22144436963 scopus 로고    scopus 로고
    • G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors
    • Sanada, K., and L.H. Tsai. 2005. G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors. Cell. 122:119-131. http://dx.doi.org/10.1016/j.cell.2005.05.009
    • (2005) Cell , vol.122 , pp. 119-131
    • Sanada, K.1    Tsai, L.H.2
  • 117
    • 15444361369 scopus 로고    scopus 로고
    • The Drosophila gene abnormal spindle encodes a novel microtubuleassociated protein that associates with the polar regions of the mitotic spindle
    • Saunders, R.D., M.C. Avides, T. Howard, C. Gonzalez, and D.M. Glover. 1997. The Drosophila gene abnormal spindle encodes a novel microtubuleassociated protein that associates with the polar regions of the mitotic spindle. J. Cell Biol. 137:881-890. http://dx.doi.org/10.1083/jcb.137.4.881
    • (1997) J. Cell Biol. , vol.137 , pp. 881-890
    • Saunders, R.D.1    Avides, M.C.2    Howard, T.3    Gonzalez, C.4    Glover, D.M.5
  • 118
    • 15844416222 scopus 로고    scopus 로고
    • Normal development of mice lacking metablastin (P19), a phosphoprotein implicated in cell cycle regulation
    • Schubart, U.K., J. Yu, J.A. Amat, Z. Wang, M.K. Hoffmann, and W. Edelmann. 1996. Normal development of mice lacking metablastin (P19), a phosphoprotein implicated in cell cycle regulation. J. Biol. Chem. 271:14062-14066. http://dx.doi.org/10.1074/jbc.271.24.14062
    • (1996) J. Biol. Chem. , vol.271 , pp. 14062-14066
    • Schubart, U.K.1    Yu, J.2    Amat, J.A.3    Wang, Z.4    Hoffmann, M.K.5    Edelmann, W.6
  • 119
    • 84860244323 scopus 로고    scopus 로고
    • Control of asymmetric cell division of mammalian neural progenitors
    • Shitamukai, A., and F. Matsuzaki. 2012. Control of asymmetric cell division of mammalian neural progenitors. Dev. Growth Differ. 54:277-286. http://dx.doi.org/10.1111/j.1440-169X.2012.01345.x
    • (2012) Dev. Growth Differ. , vol.54 , pp. 277-286
    • Shitamukai, A.1    Matsuzaki, F.2
  • 121
    • 44749092645 scopus 로고    scopus 로고
    • Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts
    • Siller, K.H., and C.Q. Doe. 2008. Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts. Dev. Biol. 319:1-9. http://dx.doi.org/10.1016/j.ydbio.2008.03.018
    • (2008) Dev. Biol. , vol.319 , pp. 1-9
    • Siller, K.H.1    Doe, C.Q.2
  • 122
    • 64049088018 scopus 로고    scopus 로고
    • Spindle orientation during asymmetric cell division
    • Siller, K.H., and C.Q. Doe. 2009. Spindle orientation during asymmetric cell division. Nat. Cell Biol. 11:365-374. http://dx.doi.org/10.1038/ncb0409-365
    • (2009) Nat. Cell Biol. , vol.11 , pp. 365-374
    • Siller, K.H.1    Doe, C.Q.2
  • 125
    • 84860130221 scopus 로고    scopus 로고
    • Anti-VEGF/VEGFR therapy for cancer: reassessing the target
    • Sitohy, B., J.A. Nagy, and H.F. Dvorak. 2012. Anti-VEGF/VEGFR therapy for cancer: reassessing the target. Cancer Res. 72:1909-1914. http://dx.doi.org/10.1158/0008-5472.CAN-11-3406
    • (2012) Cancer Res. , vol.72 , pp. 1909-1914
    • Sitohy, B.1    Nagy, J.A.2    Dvorak, H.F.3
  • 126
    • 0033769717 scopus 로고    scopus 로고
    • Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1
    • Smith, D.S., M. Niethammer, R. Ayala, Y. Zhou, M.J. Gambello, A. Wynshaw- Boris, and L.H. Tsai. 2000. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat. Cell Biol. 2:767-775. http://dx.doi.org/10.1038/35041000
    • (2000) Nat. Cell Biol. , vol.2 , pp. 767-775
    • Smith, D.S.1    Niethammer, M.2    Ayala, R.3    Zhou, Y.4    Gambello, M.J.5    Wynshaw-boris, A.6    Tsai, L.H.7
  • 129
    • 0037948857 scopus 로고    scopus 로고
    • A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans
    • Srinivasan, D.G., R.M. Fisk, H. Xu, and S. van den Heuvel. 2003. A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans. Genes Dev. 17:1225-1239. http://dx.doi.org/10 .1101/gad.1081203
    • (2003) Genes Dev. , vol.17 , pp. 1225-1239
    • Srinivasan, D.G.1    Fisk, R.M.2    Xu, H.3    van den Heuvel, S.4
  • 130
    • 0033851340 scopus 로고    scopus 로고
    • Genetic control of cell size
    • Stocker, H., and E. Hafen. 2000. Genetic control of cell size. Curr. Opin. Genet. Dev. 10:529-535. http://dx.doi.org/10.1016/S0959-437X(00)00123-4
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 529-535
    • Stocker, H.1    Hafen, E.2
  • 133
    • 0033224241 scopus 로고    scopus 로고
    • Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning
    • Swan, A., T. Nguyen, and B. Suter. 1999. Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning. Nat. Cell Biol. 1:444-449. http://dx.doi.org/10.1038/15680
    • (1999) Nat. Cell Biol. , vol.1 , pp. 444-449
    • Swan, A.1    Nguyen, T.2    Suter, B.3
  • 134
    • 33644907734 scopus 로고    scopus 로고
    • The C. elegans pvf-1 gene encodes a PDGF/VEGF-like factor able to bind mammalian VEGF receptors and to induce angiogenesis. FASEB J.
    • Tarsitano, M., S. De Falco, V. Colonna, J.D. McGhee, and M.G. Persico. 2006. The C. elegans pvf-1 gene encodes a PDGF/VEGF-like factor able to bind mammalian VEGF receptors and to induce angiogenesis. FASEB J. 20:227-233. http://dx.doi.org/10.1096/fj.05-4147com
    • (2006) , vol.20 , pp. 227-233
    • Tarsitano, M.1    Falco, S.D.2    Colonna, V.3    Mcghee, J.D.4    Persico, M.G.5
  • 135
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington'sdisease chromosomes
    • The Huntington's Disease Collaborative Research Group.
    • The Huntington's Disease Collaborative Research Group. 1993. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington'sdisease chromosomes. Cell. 72:971-983. http://dx.doi.org/10.1016/0092-8674(93)90585-E
    • (1993) Cell , vol.72 , pp. 971-983
  • 136
    • 34247863920 scopus 로고    scopus 로고
    • pVHL and GSK3beta are components of a primary cilium-maintenance signalling network
    • Thoma, C.R., I.J. Frew, C.R. Hoerner, M. Montani, H. Moch, and W. Krek. 2007. pVHL and GSK3beta are components of a primary cilium-maintenance signalling network. Nat. Cell Biol. 9:588-595. http://dx.doi.org/10.1038/ncb1579
    • (2007) Nat. Cell Biol. , vol.9 , pp. 588-595
    • Thoma, C.R.1    Frew, I.J.2    Hoerner, C.R.3    Montani, M.4    Moch, H.5    Krek, W.6
  • 138
    • 70350228242 scopus 로고    scopus 로고
    • Primary microcephaly: do all roads lead to Rome?
    • Thornton, G.K., and C.G. Woods. 2009. Primary microcephaly: do all roads lead to Rome? Trends Genet. 25:501-510. http://dx.doi.org/10.1016/j.tig.2009.09.011
    • (2009) Trends Genet , vol.25 , pp. 501-510
    • Thornton, G.K.1    Woods, C.G.2
  • 139
    • 13444261036 scopus 로고    scopus 로고
    • Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability
    • Tighe, A., V.L. Johnson, and S.S. Taylor. 2004. Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability. J. Cell Sci. 117:6339-6353. http://dx.doi.org/10.1242/jcs.01556
    • (2004) J. Cell Sci. , vol.117 , pp. 6339-6353
    • Tighe, A.1    Johnson, V.L.2    Taylor, S.S.3
  • 140
    • 36448980590 scopus 로고    scopus 로고
    • PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells
    • Toyoshima, F., S. Matsumura, H. Morimoto, M. Mitsushima, and E. Nishida. 2007. PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells. Dev. Cell. 13:796-811. http://dx.doi.org/10.1016/j.devcel.2007.10.014
    • (2007) Dev. Cell. , vol.13 , pp. 796-811
    • Toyoshima, F.1    Matsumura, S.2    Morimoto, H.3    Mitsushima, M.4    Nishida, E.5
  • 141
    • 61849114654 scopus 로고    scopus 로고
    • NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha
    • van der Voet, M., C.W. Berends, A. Perreault, T. Nguyen-Ngoc, P. Gönczy, M. Vidal, M. Boxem, and S. van den Heuvel. 2009. NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha. Nat. Cell Biol. 11:269-277. http://dx.doi.org/10.1038/ncb1834
    • (2009) Nat. Cell Biol. , vol.11 , pp. 269-277
    • van der Voet, M.1    Berends, C.W.2    Perreault, A.3    Nguyen-ngoc, T.4    Gönczy, P.5    Vidal, M.6    Boxem, M.7    van den Heuvel, S.8
  • 142
    • 8544263424 scopus 로고    scopus 로고
    • Functional role of centrosomes in spindle assembly and organization
    • Varmark, H. 2004. Functional role of centrosomes in spindle assembly and organization. J. Cell. Biochem. 91:904-914. http://dx.doi.org/10.1002/jcb.20013
    • (2004) J. Cell. Biochem. , vol.91 , pp. 904-914
    • Varmark, H.1
  • 143
    • 17744386543 scopus 로고    scopus 로고
    • Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling
    • von Stein, W., A. Ramrath, A. Grimm, M. Müller-Borg, and A. Wodarz. 2005. Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. Development. 132:1675-1686. http://dx.doi.org/10.1242/dev.01720
    • (2005) Development , vol.132 , pp. 1675-1686
    • von Stein, W.1    Ramrath, A.2    Grimm, A.3    Müller-borg, M.4    Wodarz, A.5
  • 144
    • 69449100241 scopus 로고    scopus 로고
    • Roles of the Drosophila NudE protein in kinetochore function and centrosome migration
    • Wainman, A., J. Creque, B. Williams, E.V. Williams, S. Bonaccorsi, M. Gatti, and M.L. Goldberg. 2009. Roles of the Drosophila NudE protein in kinetochore function and centrosome migration. J. Cell Sci. 122:1747-1758. http://dx.doi.org/10.1242/jcs.041798
    • (2009) J. Cell Sci. , vol.122 , pp. 1747-1758
    • Wainman, A.1    Creque, J.2    Williams, B.3    Williams, E.V.4    Bonaccorsi, S.5    Gatti, M.6    Goldberg, M.L.7
  • 145
    • 77955084820 scopus 로고    scopus 로고
    • Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82
    • Walsh, T., H. Shahin, T. Elkan-Miller, M.K. Lee, A.M. Thornton, W. Roeb, A. Abu Rayyan, S. Loulus, K.B. Avraham, M.C. King, and M. Kanaan. 2010. Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. Am. J. Hum. Genet. 87:90-94. http://dx.doi.org/10.1016/j.ajhg.2010.05.010
    • (2010) Am. J. Hum. Genet. , vol.87 , pp. 90-94
    • Walsh, T.1    Shahin, H.2    Elkan-miller, T.3    Lee, M.K.4    Thornton, A.M.5    Roeb, W.6    Abu Rayyan, A.7    Loulus, S.8    Avraham, K.B.9    King, M.C.10    Kanaan, M.11
  • 147
    • 67449119410 scopus 로고    scopus 로고
    • The role of aneuploidy in promoting and suppressing tumors
    • Weaver, B.A., and D.W. Cleveland. 2009. The role of aneuploidy in promoting and suppressing tumors. J. Cell Biol. 185:935-937. http://dx.doi.org/10.1083/jcb.200905098
    • (2009) J. Cell Biol. , vol.85 , pp. 935-937
    • Weaver, B.A.1    Cleveland, D.W.2
  • 148
    • 0030771192 scopus 로고    scopus 로고
    • Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia
    • Wells, R.A., C. Catzavelos, and S. Kamel-Reid. 1997. Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nat. Genet. 17:109-113. http://dx.doi.org/10.1038/ng0997-109
    • (1997) Nat. Genet. , vol.17 , pp. 109-113
    • Wells, R.A.1    Catzavelos, C.2    Kamel-reid, S.3
  • 149
    • 79951784680 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote Notch-dependent epidermal differentiation
    • Williams, S.E., S. Beronja, H.A. Pasolli, and E. Fuchs. 2011. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature. 470:353-358. http://dx.doi.org/10.1038/nature09793
    • (2011) Nature. , vol.470 , pp. 353-358
    • Williams, S.E.1    Beronja, S.2    Pasolli, H.A.3    Fuchs, E.4
  • 150
    • 78049276672 scopus 로고    scopus 로고
    • Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies
    • Wynshaw-Boris, A., T. Pramparo, Y.H. Youn, and S. Hirotsune. 2010. Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies. Semin. Cell Dev. Biol. 21:823-830. http://dx.doi.org/10.1016/j.semcdb.2010.07.008
    • (2010) Semin. Cell Dev. Biol. , vol.21 , pp. 823-830
    • Wynshaw-boris, A.1    Pramparo, T.2    Youn, Y.H.3    Hirotsune, S.4
  • 151
    • 0141483737 scopus 로고    scopus 로고
    • Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome
    • Yamashita, Y.M., D.L. Jones, and M.T. Fuller. 2003. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science. 301:1547-1550. http://dx.doi.org/10.1126/science.1087795
    • (2003) Science. , vol.301 , pp. 1547-1550
    • Yamashita, Y.M.1    Jones, D.L.2    Fuller, M.T.3
  • 152
    • 38849091345 scopus 로고    scopus 로고
    • Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division
    • Yingling, J., Y.H. Youn, D. Darling, K. Toyo-Oka, T. Pramparo, S. Hirotsune, and A. Wynshaw-Boris. 2008. Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell. 132:474-486. http://dx.doi.org/10.1016/j.cell.2008.01.026
    • (2008) Cell , vol.132 , pp. 474-486
    • Yingling, J.1    Youn, Y.H.2    Darling, D.3    Toyo-oka, K.4    Pramparo, T.5    Hirotsune, S.6    Wynshaw-boris, A.7
  • 153
  • 154
    • 77951174042 scopus 로고    scopus 로고
    • LGN regulates mitotic spindle orientation during epithelial morphogenesis
    • Zheng, Z., H. Zhu, Q. Wan, J. Liu, Z. Xiao, D.P. Siderovski, and Q. Du. 2010. LGN regulates mitotic spindle orientation during epithelial morphogenesis. J. Cell Biol. 189:275-288. http://dx.doi.org/10.1083/jcb.200910021
    • (2010) J. Cell Biol. , vol.189 , pp. 275-288
    • Zheng, Z.1    Zhu, H.2    Wan, Q.3    Liu, J.4    Xiao, Z.5    Siderovski, D.P.6    Du, Q.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.