Brain damage in methylmalonic aciduria: 2-methylcitrate induces cerebral ammonium accumulation and apoptosis in 3D organotypic brain cell cultures.

Orphanet journal of rare diseases

Volumn 8, Issue , 2013, Pages

  Jafari, Paris ^a   Braissant, Olivier ^b   Zavadakova, Petra ^b   Henry, Hugues ^b   Bonafé, Luisa ^b   Ballhausen, Diana ^b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLCITRIC ACID; 2-METHYLCITRIC ACID; CASPASE 3; CITRIC ACID; METHYLMALONIC ACID; QUATERNARY AMMONIUM DERIVATIVE;

ANIMAL; APOPTOSIS; ARTICLE; BRAIN; CELL CULTURE; CULTURE MEDIUM; DISORDERS OF AMINO ACID AND PROTEIN METABOLISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; PREGNANCY; RAT; SPRAGUE DAWLEY RAT; URINE; WESTERN BLOTTING;

AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CASPASE 3; CELLS, CULTURED; CITRATES; CULTURE MEDIA; FEMALE; IMMUNOHISTOCHEMISTRY; METHYLMALONIC ACID; PREGNANCY; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84871955800     PISSN: None     EISSN: 17501172     Source Type: None    
DOI: 10.1186/1750-1172-8-4     Document Type: Article

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