Differences in sexual desire between women with clinical versus biochemical signs of hyperandrogenism in polycystic ovarian syndrome

Hormones and Behavior

Volumn 63, Issue 1, 2013, Pages 65-71

  Rellini, A H ^a   Stratton, N ^b   Tonani, S ^c   Santamaria, V ^c   Brambilla, E ^c,d   Nappi, R E ^c,d  

^a UNIVERSITY OF VERMONT   (United States)

^b Gina Cody School of Engineering and Computer Science   (Canada)

^c IRCCS   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

Androgens; Female sexuality; Free testosterone; PCOS; Sexual desire

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; PRASTERONE SULFATE; TESTOSTERONE;

ACNE; ADULT; ALOPECIA; ARTICLE; ASSOCIATION; CONTROLLED STUDY; CUES OF SEXUAL DESIRE SCALE; FEMALE; HIRSUTISM; HUMAN; HUMAN RELATION; HYPERANDROGENISM; LIBIDO; MAJOR CLINICAL STUDY; MATE CHOICE; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE;

ADOLESCENT; ADULT; ANDROGENS; FEMALE; HUMANS; HYPERANDROGENISM; LIBIDO; POLYCYSTIC OVARY SYNDROME; SEXUAL BEHAVIOR;

EID: 84871935831     PISSN: 0018506X     EISSN: 10956867     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2012.10.013     Document Type: Article

References (40)

1. Bachmann G., Bancroft J., Braunstein G., Burger H., Davis S., Dennerstein, et al. Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment. Fertil. Steril. 2002, 77:660-665.
2. Bancroft J. Androgens and sexual function in men and women. Androgens in Health and Disease 2003, 259-290. Humana Press, Totowa, New Jersey. C.J. Bagatell, W.J. Bremner (Eds.).
3. Basson R. Androgen replacement for women. Can. Fam. Physician 1999, 45:2100-2107.
4. Basson R. Hormones and sexuality: current complexities and future directions. Maturitas 2007, 57:66-70.
5. Battaglia C., Nappi R.E., Mancini F., Cianciosi A., Persico N., Busacchi P., Facchinetti F., Sisti G. PCOS, sexuality, and clitoral vascularisation: a pilot study. J. Sex Med. 2008, 5:2886-2894. 10.1111/j.1743-6109.2008.01010.x.
6. Bullivant S.B., Sellergren S.A., Stern K., Spencer N.A., Jacob S., Mennella J.A., McClintock M.K. Women's sexual experience during the menstrual cycle: identification of the sexual phase by non invasive measurement of luteinizing hormone. J. Sex. Res. 2004, 41:82-93.
7. Buss D.M. Sex differences in human mate preferences: evolutionary hypotheses tested in 37 cultures. Behav. Brain Sci. 1989, 12:1-49.
8. Cooper M.L., Shapiro C.M., Powers A.M. Motivations for sex and risky sexual behaviour among adolescents and young adults: a functional perspective. J. Pers. Soc. Psychol. 1998, 75:1528-1558.
9. Davis S., Tran J. Testosterone influences libido and well being in women. Trends Endocrinol. Metab. 2001, 12:33-37.
10. Davis S.R., McCloud P., Strauss B.J.G., Burger H. Testosterone enhances estradiol's effects on post-menopausal bone density and sexuality. Maturitas 1995, 21:227-236.
11. Davis S.R., Davison S.L., Donath S., Bell R.J. Circulating androgen levels and self-reported sexual function in women. J. Am. Med. Assoc. 2005, 294:91-96. 10.1001/jama.294.1.91.
12. Polycystic Ovary Syndrome: Current Controversies, from Ovary to the Pancreas 2008, Humana Press, Totowa, NJ. A. Dunaif, R.J. Chang, S. Franks, R.S. Legro (Eds.).
13. Flöter A.R. Testosterone treatment in women: an overview. Curr. Womens Health Rev. 2009, 5(29-43):29.
14. Flöter A.R. Testosterone Treatment in Women: An overview. Current Women's Health Reviews 2009, 5:29-43.
15. Fruzzetti F., Perini D., Lazzarini V., Parrini D., Genazzani A.R. Adolescent girls with polycystic ovary syndrome showing different phenotypes have a different metabolic profile associated with increasing androgen levels. Fertil. Steril. 2009, 92:626-634.
16. Graham C.A., Bancroft J., Doll H.A., Greco T., Tanner A. Does oral contraceptive-induced reduction in free testosterone adversely affect the sexuality or mood of women?. Psychoneuroendocrinology 2007, 32:246-255.
17. Janssen O.E., Hahn S., Tan S., Benson S., Elsenbruch S. Mood and sexual function in polycystic ovary syndrome. Semin. Reprod. Med. 2008, 26:45-52.
18. Knapp R., Neff B.D. Steroid hormones in bluegill, a species with male alternative reproductive tactics including female mimicry. Biol. Lett. 2007, 3:628-631. 10.1098/rsbl.2007.0379.
19. Levine S. Reexploring the concept of sexual desire. J. Sex Marital Ther. 2002, 28:39-51.
20. Levine S. The nature of sexual desire, a clinician's perspective. Arch. Sex. Behav. 2003, 32:279-285.
21. Lukaszewski A.W., Roney J.R. Estimated hormones predict women's mate preferences for dominant personality traits. Pers. Indiv. Differ. 2009, 47:191-196.
22. McCall K., Meston C. Cues resulting in desire for sexual activity in women. J. Sex Med. 2006, 3:838-852. 10.1111/j.1743-6109.2006.00301.x.
23. McCall K., Meston C. Differences between pre- and postmenopausal women in cues for sexual desire. J. Sex. Med. 2007, 4:364-371.
24. Meston C.M., Buss D.M. Why humans have sex. Arch. Sex. Behav. 2007, 36:477-507. 10.1007/s10508-007-9175-2.
25. Nestler J.E. Errors in the measurement of plasma free testosterone - Author's response. Journal of Clinical Endocrinology and Metabolism 2007, 82:2015.
26. Norman R.J., Dewailly D., Legro R.S., Hickey T.E. Polycystic ovary syndrome. Lancet 2007, 370:685-697.
27. Pfaus J.G. Pathways of sexual desire. J. Sex. Med. 2009, 6:1506-1533. 10.1111/j.1743-6109.2009.01309.x.
28. Rivera-Woll L.M., Papalia M., Davis S.R., Burge H.G. Androgen insufficiency in women: diagnostic and therapeutic implications. Hum. Reprod. Update 2004, 10:421-432.
29. Rotterdam ESHRE/ASRM-Sponsored PCOS ConsensusWorkshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil. Steril. 2004, 8:19-25.
30. Rosner W. Errors in the measurement of plasma free testosterone. Journal of Clinical Endocrinology and Metabolism 2007, 82:2014-2015.
31. Santoro N., Torren J., Crawford S., Allsworth J.E., Finkelstein J.S., Gold E.B., et al. Correlates of circulating androgens in mid-life women: the study of women's health across the nation. J. Clin. Endocrinol. Metab. 2005, 90:4836-4845. 10.1210/jc.2004-2063.
32. Tuiten A., Van Honk J., Koppeschaar H., Bernaards C., Thijssen J., Verbaten R. Time course of effects of testosterone administration on sexual arousal in women. Arch. Gen. Psychiatry 2000, 57:149-153.
33. Tuiten A., van Honk J., Verbaten R., Laan E., Everaerd W., Stam H. Can sublingual testosterone increase subjective and physiological measures of laboratory induced sexual arousal?. Arch. Gen. Psychiatry 2002, 59:465-466.
34. van Anders S.M., Goldey K.L. Testosterone and partnering are linked via relationship status for women and 'relationship orientation' for men. Horm. Behav. 2010, 58:820-826.
35. van Anders S.M., Watson N.V. Relationship status and testosterone in North American heterosexual and non-heterosexual men and women: cross-sectional and longitudinal data. Psychoneuroendocrinology 2006, 31:715-723.
36. van Anders S.M., Watson N.V. Testosterone levels in women and men who are single, in long-distance relationships, or same-city relationships. Horm. Behav. 2007, 51:286-291.
37. van Anders S.M., Hamilton L.D., Watson N.V. Multiple partners are associated with higher testosterone in North American men and women. Horm. Behav. 2007, 51:454-459.
38. van Anders S.M., Brotto L., Farrell J., Yule M. Associations among physiological and subjective sexual response, sexual desire, and salivary steroid hormones in healthy premenopausal women. J. Sex. Med 2009, 6:739-751. 10.1111/j.1743-6109.2008.01123.x.
39. Wierman M.E., Nappi R.E., Avis N., Davis S., Labrie F., Rosner W., Shifren J.L. Endocrine aspects of women's sexual function. J. Sex. Med. 2010, 7:561-585.
40. Wingfield J.C., Lynn S.E., Soma K.K. Avoiding the 'costs' of testosterone: ecological bases of hormone-behavior interactions. Brain Behav. Evol. 2001, 57:239-251.